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Yaqing Xu

Publications and source records attributed to Yaqing Xu.

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Shaping the Evolutionary Dynamics of Robot Morphology via Adaptive Control Learning

Robot co-design via bi-level optimization couples within-lifetime controller learning for fitness evaluation with cross-generational morphological evolution. Prior work has established that well-adapted morphology facilitates faster control learning, a property termed morphological intelligence. Yet how control learning reciprocally shapes morphological evolution remains unexplored. This paper examines both directions for a holistic account of brain-body interplay. We first show that morphological contributions to control learning decouple into two orthogonal dimensions. We formalize the convergence speed as morphological intelligence and identify the performance ceiling as a complementary quantity termed true potential. A concise functional relation is then established to jointly characterize both quantities from individual learning curves, which, when aggregated at the population level, capture evolutionary profiles. Through extensive experiments on simulated voxel-based soft robots, we reveal that premature fitness evaluation systematically underestimates true potential and biases selection towards fast learners. This restricts design space exploration, compromising both optimization efficiency and morphological diversity. Notably, the widely recognized morphological Baldwin effect emerges as an artifact of this bias rather than a general evolutionary tendency. We therefore propose AdaControl, which monitors disproportionate selection for morphological intelligence during evolution and allocates minimally sufficient control learning for unbiased fitness evaluation. With AdaControl, a simple genetic algorithm rivals state-of-the-art generative-model-based co-design methods in discovering diverse high-performing designs while cutting computation by up to 80% versus exhaustive control.

cs.RO

Multidimensional molecular changes-environment interaction analysis for disease outcomes

For the outcomes and phenotypes of complex diseases, multiple types of molecular (genetic, genomic, epigenetic, etc.) changes, environmental risk factors, and their interactions have been found to have important contributions. In each of the existing studies, only the interactions between one type of molecular changes and environmental risk factors have been analyzed. In recent biomedical studies, multidimensional profiling, under which data on multiple types of molecular changes is collected on the same subjects, is becoming popular. A myriad of recent studies have shown that collectively analyzing multiple types of molecular changes is not only biologically sensible but also leads to improved estimation and prediction. In this study, we conduct M-E interaction analysis, with M standing for multidimensional molecular changes and E standing for environmental risk factors, which can accommodate multiple types of molecular measurements and sufficiently account for their overlapping information (attributable to regulations) as well as independent information. The proposed approach is based on the penalization technique, has a solid statistical ground, and can be effectively realized. Extensive simulation shows that it outperforms multiple closely relevant alternatives. In the analysis of TCGA (The Cancer Genome Atlas) data on lung adenocarcinoma and cutaneous melanoma, sensible findings with superior stability and prediction are made.

stat.ME