arXiv subjects

Yash Sharma

Publications and source records attributed to Yash Sharma.

At least 19 recordsLinked to original sources

arXiv2026

High-redshift GRB 140304A at z = 5.282 with flaring activity: A multi-wavelength study

Context. This article presents a detailed multi-wavelength analysis of GRB 140304A at z = 5.282, having uncommon late-time flaring features. The aim is to study GRB 140304A and other similar bursts to understand stellar evolution and formation processes at high-z. Aims. GRBs at high-z, possible flaring activities at different frequencies seen at relatively late-times, help to constrain temporal correlation among contemporaneous flares. In the present study, we plan to constrain such a temporal and spectral study for a sample of high-z bursts, including GRB 140304A. Methods. We use Swift, Fermi, and ground-based observations to constrain the temporal and spectral properties of the prompt and afterglow emissions. Using the cross-correlation function, we calculate the spectral lag in the light curves observed in two energy bands of Swift's Burst Alert Telescope (BAT) and X-ray Telescope (XRT). Results. Parameter evolution of the prompt emission analysis reveals a hard-to-soft evolution of the spectral peak energy (Ep) and the magnetic field strength (B), consistent with the typical population of long GRBs. For GRB 140304A, a rare pattern of spectral lag evolution having positive lag in the early BAT light curves, but no lag is observed in the XRT light curves. We have also observed systematic time delays among the peak times of flares in three different bands, but the optical flares exhibit a morphological correspondence with X-ray or gamma-ray flares. Conclusions. Our analysis shows that the observed positive spectral lag in GRB 140304A is closely related to the hard-to-soft spectral evolution during the prompt emission phase, as seen in some of the other long GRBs. Additionally, there is a clear connection between gamma-ray, X-ray and optical flares with prompt emission, which are produced through synchrotron radiation during rapid bulk acceleration within the emitting region.

astro-ph.HE↗

arXiv2026

MALTopic: Multi-Agent LLM Topic Modeling Framework

Topic modeling is a crucial technique for extracting latent themes from unstructured text data, particularly valuable in analyzing survey responses. However, traditional methods often only consider free-text responses and do not natively incorporate structured or categorical survey responses for topic modeling. And they produce abstract topics, requiring extensive human interpretation. To address these limitations, we propose the Multi-Agent LLM Topic Modeling Framework (MALTopic). This framework decomposes topic modeling into specialized tasks executed by individual LLM agents: an enrichment agent leverages structured data to enhance textual responses, a topic modeling agent extracts latent themes, and a deduplication agent refines the results. Comparative analysis on a survey dataset demonstrates that MALTopic significantly improves topic coherence, diversity, and interpretability compared to LDA and BERTopic. By integrating structured data and employing a multi-agent approach, MALTopic generates human-readable topics with enhanced contextual relevance, offering a more effective solution for analyzing complex survey data.

cs.CL↗

arXiv2025

Nephrobase Cell+: Multimodal Single-Cell Foundation Model for Decoding Kidney Biology

Background: Large foundation models have revolutionized single-cell analysis, yet no kidney-specific model currently exists, and it remains unclear whether organ-focused models can outperform generalized models. The kidney's complex cellular architecture further complicate integration of large-scale omics data, where current frameworks trained on limited datasets struggle to correct batch effects, capture cross-modality variation, and generalize across species. Methods: We developed Nephrobase Cell+, the first kidney-focused large foundation model, pretrained on ~100 billion tokens from ~39.5 million single-cell and single-nucleus profiles across 4,319 samples. Nephrobase Cell+ uses a transformer-based encoder-decoder architecture with gene-token cross-attention and a mixture-of-experts module for scalable representation learning. Results: Nephrobase Cell+ sets a new benchmark for kidney single-cell analysis. It produces tightly clustered, biologically coherent embeddings in human and mouse kidneys, far surpassing previous foundation models such as Geneformer, scGPT, and UCE, as well as traditional methods such as PCA and autoencoders. It achieves the highest cluster concordance and batch-mixing scores, effectively removing donor/assay batch effects while preserving cell-type structure. Cross-species evaluation shows superior alignment of homologous cell types and >90% zero-shot annotation accuracy for major kidney lineages in both human and mouse. Even its 1B-parameter and 500M variants consistently outperform all existing models. Conclusions: Nephrobase Cell+ delivers a unified, high-fidelity representation of kidney biology that is robust, cross-species transferable, and unmatched by current single-cell foundation models, offering a powerful resource for kidney genomics and disease research.

q-bio.GN↗

arXiv2025

Towards physician-centered oversight of conversational diagnostic AI

Recent work has demonstrated the promise of conversational AI systems for diagnostic dialogue. However, real-world assurance of patient safety means that providing individual diagnoses and treatment plans is considered a regulated activity by licensed professionals. Furthermore, physicians commonly oversee other team members in such activities, including nurse practitioners (NPs) or physician assistants/associates (PAs). Inspired by this, we propose a framework for effective, asynchronous oversight of the Articulate Medical Intelligence Explorer (AMIE) AI system. We propose guardrailed-AMIE (g-AMIE), a multi-agent system that performs history taking within guardrails, abstaining from individualized medical advice. Afterwards, g-AMIE conveys assessments to an overseeing primary care physician (PCP) in a clinician cockpit interface. The PCP provides oversight and retains accountability of the clinical decision. This effectively decouples oversight from intake and can thus happen asynchronously. In a randomized, blinded virtual Objective Structured Clinical Examination (OSCE) of text consultations with asynchronous oversight, we compared g-AMIE to NPs/PAs or a group of PCPs under the same guardrails. Across 60 scenarios, g-AMIE outperformed both groups in performing high-quality intake, summarizing cases, and proposing diagnoses and management plans for the overseeing PCP to review. This resulted in higher quality composite decisions. PCP oversight of g-AMIE was also more time-efficient than standalone PCP consultations in prior work. While our study does not replicate existing clinical practices and likely underestimates clinicians' capabilities, our results demonstrate the promise of asynchronous oversight as a feasible paradigm for diagnostic AI systems to operate under expert human oversight for enhancing real-world care.

cs.AI↗

arXiv2025

Advancing Conversational Diagnostic AI with Multimodal Reasoning

Large Language Models (LLMs) have demonstrated great potential for conducting diagnostic conversations but evaluation has been largely limited to language-only interactions, deviating from the real-world requirements of remote care delivery. Instant messaging platforms permit clinicians and patients to upload and discuss multimodal medical artifacts seamlessly in medical consultation, but the ability of LLMs to reason over such data while preserving other attributes of competent diagnostic conversation remains unknown. Here we advance the conversational diagnosis and management performance of the Articulate Medical Intelligence Explorer (AMIE) through a new capability to gather and interpret multimodal data, and reason about this precisely during consultations. Leveraging Gemini 2.0 Flash, our system implements a state-aware dialogue framework, where conversation flow is dynamically controlled by intermediate model outputs reflecting patient states and evolving diagnoses. Follow-up questions are strategically directed by uncertainty in such patient states, leading to a more structured multimodal history-taking process that emulates experienced clinicians. We compared AMIE to primary care physicians (PCPs) in a randomized, blinded, OSCE-style study of chat-based consultations with patient actors. We constructed 105 evaluation scenarios using artifacts like smartphone skin photos, ECGs, and PDFs of clinical documents across diverse conditions and demographics. Our rubric assessed multimodal capabilities and other clinically meaningful axes like history-taking, diagnostic accuracy, management reasoning, communication, and empathy. Specialist evaluation showed AMIE to be superior to PCPs on 7/9 multimodal and 29/32 non-multimodal axes (including diagnostic accuracy). The results show clear progress in multimodal conversational diagnostic AI, but real-world translation needs further research.

cs.CL↗

arXiv2025

CorrNetDroid: Android Malware Detector leveraging a Correlation-based Feature Selection for Network Traffic features

Copious mobile operating systems exist in the market, but Android remains the user's choice. Meanwhile, its growing popularity has also attracted malware developers. Researchers have proposed various static solutions for Android malware detection. However, stealthier malware evade static analysis. This raises the need for a robust Android malware detection system capable of dealing with advanced threats and overcoming the shortcomings of static analysis. Hence, this work proposes a dynamic analysis-based Android malware detection system, CorrNetDroid, that works over network traffic flows. Many traffic features exhibit overlapping ranges in normal and malware datasets. Therefore, we first rank the features using two statistical measures, crRelevance and Normalized Mean Residue Similarity (NMRS), to assess feature-class and feature-feature correlations. Thereafter, we introduce a novel correlation-based feature selection algorithm that applies NMRS on crRelevance rankings to identify the optimal feature subset for Android malware detection. Experimental results highlight that our model effectively reduces the feature set while detecting Android malware with 99.50 percent accuracy when considering only two network traffic features. Furthermore, our experiments demonstrate that the NMRS-based algorithm on crRelevance rankings outperforms statistical tests such as chi-square, ANOVA, Mann-Whitney U test, and Kruskal-Wallis test. In addition, our model surpasses various state-of-the-art Android malware detection techniques in terms of detection accuracy.

cs.CR↗

arXiv2025

Pretraining Frequency Predicts Compositional Generalization of CLIP on Real-World Tasks

We investigate the success conditions for compositional generalization of CLIP models on real-world data through performance prediction. Prior work shows that CLIP requires exponentially more pretraining data for linear performance gains on individual concepts. This sample-inefficient scaling could be mitigated if CLIP systematically understood new inputs as compositions of learned components, allowing rare observation to be mapped to common concepts. To explore CLIP's compositional generalization ability, we filter retrieval corpora for samples with object combinations not present in the pretraining corpus. We show that CLIP's performance on these samples can be accurately predicted from the pretraining frequencies of individual objects. Our findings demonstrate that CLIP learns to disentangle objects observed in its pretraining data and can recompose them straightforwardly. Additionally, we are the first to show how this ability scales with pretraining data. For data curation in practice, our results suggest that balancing object occurrences improves generalization, which should benefit CLIP's efficiency and accuracy without scaling data volume.

cs.LG↗

arXiv2024

Influence of superconductor dirtiness on the SNSPD sensitivity-bandwidth trade-off

Practical superconducting nanowire single photon detectors (SNSPDs) demonstrate a strong trade-off between detection sensitivity and the reset time. Often, there are wide variations in sensitivity and response times from SNSPDs of the same superconducting material. Here, using detailed physical models, we show that the dirtiness in a superconductor enforces a sensitivity and bandwidth trade-off in all practical devices. More importantly, a certain degree of dirtiness is a necessary requirement for achieving single photon detection. Under typical bias conditions close to the transition setpoints, the minimum number of photons required to register a voltage pulse decreases by the dirtiness parameter (Ioffe-Regel parameter) and the reset time of SNSPD increases by the same dirtiness parameter, thereby giving a constant value for the sensitivity-bandwidth product. The constant is weakly modified by biasing current and the temperature. Since dirtiness in the superconducting nanowire is a physically controllable parameter with an important bearing on the final response of an SNSPD, this work opens new opportunities to develop SNSPD devices with engineered sensitivity-bandwidth setpoint as dictated by an application.

cond-mat.supr-con↗

arXiv2024

No "Zero-Shot" Without Exponential Data: Pretraining Concept Frequency Determines Multimodal Model Performance

Web-crawled pretraining datasets underlie the impressive "zero-shot" evaluation performance of multimodal models, such as CLIP for classification/retrieval and Stable-Diffusion for image generation. However, it is unclear how meaningful the notion of "zero-shot" generalization is for such multimodal models, as it is not known to what extent their pretraining datasets encompass the downstream concepts targeted for during "zero-shot" evaluation. In this work, we ask: How is the performance of multimodal models on downstream concepts influenced by the frequency of these concepts in their pretraining datasets? We comprehensively investigate this question across 34 models and five standard pretraining datasets (CC-3M, CC-12M, YFCC-15M, LAION-400M, LAION-Aesthetics), generating over 300GB of data artifacts. We consistently find that, far from exhibiting "zero-shot" generalization, multimodal models require exponentially more data to achieve linear improvements in downstream "zero-shot" performance, following a sample inefficient log-linear scaling trend. This trend persists even when controlling for sample-level similarity between pretraining and downstream datasets, and testing on purely synthetic data distributions. Furthermore, upon benchmarking models on long-tailed data sampled based on our analysis, we demonstrate that multimodal models across the board perform poorly. We contribute this long-tail test set as the "Let it Wag!" benchmark to further research in this direction. Taken together, our study reveals an exponential need for training data which implies that the key to "zero-shot" generalization capabilities under large-scale training paradigms remains to be found.

cs.CV↗

arXiv2024

Gujarati-English Code-Switching Speech Recognition using ensemble prediction of spoken language

An important and difficult task in code-switched speech recognition is to recognize the language, as lots of words in two languages can sound similar, especially in some accents. We focus on improving performance of end-to-end Automatic Speech Recognition models by conditioning transformer layers on language ID of words and character in the output in an per layer supervised manner. To this end, we propose two methods of introducing language specific parameters and explainability in the multi-head attention mechanism, and implement a Temporal Loss that helps maintain continuity in input alignment. Despite being unable to reduce WER significantly, our method shows promise in predicting the correct language from just spoken data. We introduce regularization in the language prediction by dropping LID in the sequence, which helps align long repeated output sequences.

cs.CL↗

arXiv2024

MOSAIC: Modular Foundation Models for Assistive and Interactive Cooking

We present MOSAIC, a modular architecture for coordinating multiple robots to (a) interact with users using natural language and (b) manipulate an open vocabulary of everyday objects. MOSAIC employs modularity at several levels: it leverages multiple large-scale pre-trained models for high-level tasks like language and image recognition, while using streamlined modules designed for low-level task-specific control. This decomposition allows us to reap the complementary benefits of foundation models as well as precise, more specialized models. Pieced together, our system is able to scale to complex tasks that involve coordinating multiple robots and humans. First, we unit-test individual modules with 180 episodes of visuomotor picking, 60 episodes of human motion forecasting, and 46 online user evaluations of the task planner. We then extensively evaluate MOSAIC with 60 end-to-end trials. We discuss crucial design decisions, limitations of the current system, and open challenges in this domain. The project's website is at https://portal-cornell.github.io/MOSAIC/

cs.RO↗

arXiv2024

Nonparametric Partial Disentanglement via Mechanism Sparsity: Sparse Actions, Interventions and Sparse Temporal Dependencies

This work introduces a novel principle for disentanglement we call mechanism sparsity regularization, which applies when the latent factors of interest depend sparsely on observed auxiliary variables and/or past latent factors. We propose a representation learning method that induces disentanglement by simultaneously learning the latent factors and the sparse causal graphical model that explains them. We develop a nonparametric identifiability theory that formalizes this principle and shows that the latent factors can be recovered by regularizing the learned causal graph to be sparse, under some assumptions such as the absence of instantaneous causal effects between latent factors. More precisely, we show identifiability up to a novel equivalence relation we call consistency, which allows some latent factors to remain entangled (hence the term partial disentanglement). To describe the structure of this entanglement, we introduce the notions of entanglement graphs and graph preserving functions. We further provide a graphical criterion which guarantees complete disentanglement, that is identifiability up to permutations and element-wise transformations. We demonstrate the scope of the mechanism sparsity principle as well as the assumptions it relies on with several worked out examples. For instance, the framework shows how one can leverage multi-node interventions with unknown targets on the latent factors to disentangle them. We further draw connections between our nonparametric results and the now popular exponential family assumption. Lastly, we propose an estimation procedure based on variational autoencoders and a sparsity constraint and demonstrate it on various synthetic datasets. This work is meant to be a significantly extended version of a work published at CLeaR 2022.

stat.ML↗

arXiv2023

Towards Accurate Differential Diagnosis with Large Language Models

An accurate differential diagnosis (DDx) is a cornerstone of medical care, often reached through an iterative process of interpretation that combines clinical history, physical examination, investigations and procedures. Interactive interfaces powered by Large Language Models (LLMs) present new opportunities to both assist and automate aspects of this process. In this study, we introduce an LLM optimized for diagnostic reasoning, and evaluate its ability to generate a DDx alone or as an aid to clinicians. 20 clinicians evaluated 302 challenging, real-world medical cases sourced from the New England Journal of Medicine (NEJM) case reports. Each case report was read by two clinicians, who were randomized to one of two assistive conditions: either assistance from search engines and standard medical resources, or LLM assistance in addition to these tools. All clinicians provided a baseline, unassisted DDx prior to using the respective assistive tools. Our LLM for DDx exhibited standalone performance that exceeded that of unassisted clinicians (top-10 accuracy 59.1% vs 33.6%, [p = 0.04]). Comparing the two assisted study arms, the DDx quality score was higher for clinicians assisted by our LLM (top-10 accuracy 51.7%) compared to clinicians without its assistance (36.1%) (McNemar's Test: 45.7, p < 0.01) and clinicians with search (44.4%) (4.75, p = 0.03). Further, clinicians assisted by our LLM arrived at more comprehensive differential lists than those without its assistance. Our study suggests that our LLM for DDx has potential to improve clinicians' diagnostic reasoning and accuracy in challenging cases, meriting further real-world evaluation for its ability to empower physicians and widen patients' access to specialist-level expertise.

cs.CY↗

arXiv2023

Attribute Diversity Determines the Systematicity Gap in VQA

Although modern neural networks often generalize to new combinations of familiar concepts, the conditions that enable such compositionality have long been an open question. In this work, we study the systematicity gap in visual question answering: the performance difference between reasoning on previously seen and unseen combinations of object attributes. To test, we introduce a novel diagnostic dataset, CLEVR-HOPE. We find that the systematicity gap is not reduced by increasing the quantity of training data, but is reduced by increasing the diversity of training data. In particular, our experiments suggest that the more distinct attribute type combinations are seen during training, the more systematic we can expect the resulting model to be.

cs.LG↗

arXiv2023

Demo2Code: From Summarizing Demonstrations to Synthesizing Code via Extended Chain-of-Thought

Language instructions and demonstrations are two natural ways for users to teach robots personalized tasks. Recent progress in Large Language Models (LLMs) has shown impressive performance in translating language instructions into code for robotic tasks. However, translating demonstrations into task code continues to be a challenge due to the length and complexity of both demonstrations and code, making learning a direct mapping intractable. This paper presents Demo2Code, a novel framework that generates robot task code from demonstrations via an extended chain-of-thought and defines a common latent specification to connect the two. Our framework employs a robust two-stage process: (1) a recursive summarization technique that condenses demonstrations into concise specifications, and (2) a code synthesis approach that expands each function recursively from the generated specifications. We conduct extensive evaluation on various robot task benchmarks, including a novel game benchmark Robotouille, designed to simulate diverse cooking tasks in a kitchen environment. The project's website is available at https://portal-cornell.github.io/demo2code/

cs.RO↗

arXiv2023

On Transfer of Adversarial Robustness from Pretraining to Downstream Tasks

As large-scale training regimes have gained popularity, the use of pretrained models for downstream tasks has become common practice in machine learning. While pretraining has been shown to enhance the performance of models in practice, the transfer of robustness properties from pretraining to downstream tasks remains poorly understood. In this study, we demonstrate that the robustness of a linear predictor on downstream tasks can be constrained by the robustness of its underlying representation, regardless of the protocol used for pretraining. We prove (i) a bound on the loss that holds independent of any downstream task, as well as (ii) a criterion for robust classification in particular. We validate our theoretical results in practical applications, show how our results can be used for calibrating expectations of downstream robustness, and when our results are useful for optimal transfer learning. Taken together, our results offer an initial step towards characterizing the requirements of the representation function for reliable post-adaptation performance.

cs.LG↗

arXiv2023

The intersection of video capsule endoscopy and artificial intelligence: addressing unique challenges using machine learning

Introduction: Technical burdens and time-intensive review processes limit the practical utility of video capsule endoscopy (VCE). Artificial intelligence (AI) is poised to address these limitations, but the intersection of AI and VCE reveals challenges that must first be overcome. We identified five challenges to address. Challenge #1: VCE data are stochastic and contains significant artifact. Challenge #2: VCE interpretation is cost-intensive. Challenge #3: VCE data are inherently imbalanced. Challenge #4: Existing VCE AIMLT are computationally cumbersome. Challenge #5: Clinicians are hesitant to accept AIMLT that cannot explain their process. Methods: An anatomic landmark detection model was used to test the application of convolutional neural networks (CNNs) to the task of classifying VCE data. We also created a tool that assists in expert annotation of VCE data. We then created more elaborate models using different approaches including a multi-frame approach, a CNN based on graph representation, and a few-shot approach based on meta-learning. Results: When used on full-length VCE footage, CNNs accurately identified anatomic landmarks (99.1%), with gradient weighted-class activation mapping showing the parts of each frame that the CNN used to make its decision. The graph CNN with weakly supervised learning (accuracy 89.9%, sensitivity of 91.1%), the few-shot model (accuracy 90.8%, precision 91.4%, sensitivity 90.9%), and the multi-frame model (accuracy 97.5%, precision 91.5%, sensitivity 94.8%) performed well. Discussion: Each of these five challenges is addressed, in part, by one of our AI-based models. Our goal of producing high performance using lightweight models that aim to improve clinician confidence was achieved.

q-bio.QM↗

arXiv2023

Stress-induced Artificial neuron spiking in Diffusive memristors

Diffusive memristors owing to their ability to produce current spiking when a constant or slowly changing voltage is applied are competitive candidates for the development of artificial electronic neurons. These artificial neurons can be integrated into various prospective autonomous and robotic systems as sensors, e.g. ones implementing object grasping and classification. We report here Ag nanoparticle-based diffusive memristor prepared on a flexible polyethylene terephthalate (PET) substrate in which the electric spiking behaviour was induced by the electric voltage under an additional stimulus of external mechanical impact. By changing the magnitude and frequency of the mechanical impact, we are able to manipulate the spiking response of our artificial neuron. This functionality to control the spiking characterstics paves a pathway for the development of touch-perception sensors that can convert local pressure into electrical spikes for further processing in neural networks. We have proposed a mathematical model which captures the operation principle of the fabricated memristive sensors and qualitatively describes the measured spiking behaviour.

physics.app-ph↗