Ye Geng | Searcharxiv

arXiv2026

Propagating Structural Guidance: Synthesizing Fluorescein Angiography from Fundus Images and Sparse OCT Scans

Fundus fluorescein angiography (FFA) is critical for assessing retinal vascular abnormalities, but its acquisition is invasive and not always feasible. In contrast, color fundus photography (CFP) is non-invasive and widely accessible, which has motivated studies on CFP-to-FFA synthesis. However, prior works rely solely on CFP surface texture, fundamentally limiting the ability to reconstruct functional vascular information and subtle pathological changes. To address this, we propose a novel framework that synthesizes FFA from CFP with structural guidance provided by optical coherence tomography (OCT). We construct a multi-modal retinal imaging dataset with paired CFP, FFA, and OCT from 3,676 patient eyes--the first tri-modally aligned dataset in retinal imaging. To bridge the spatial gap between OCT and fundus modalities, we propose a Spatially Aligned Cross-Modal Fusion (SACMF) module that projects depth-resolved OCT features onto the fundus plane and injects them into the CFP encoder via adaptive layer normalization. Beyond feature fusion, we further introduce Token-wise Cross-Modality Alignment (TCMA), a token-level contrastive learning strategy that explicitly aligns CFP and FFA representations at corresponding spatial positions. Our method achieves superior synthesis performance compared to state-of-the-art methods. Moreover, extensive experiments demonstrate that the FFA images synthesized by our approach bring greater improvements in downstream disease diagnosis performance than existing methods, highlighting the clinical potential of our approach as a non-invasive decision-support tool in routine workflows. The code is available at https://github.com/while-plus/OCT-guide-FFA-Syn.

cs.CV↗

arXiv2022

AgileWatts: An Energy-Efficient CPU Core Idle-State Architecture for Latency-Sensitive Server Applications

User-facing applications running in modern datacenters exhibit irregular request patterns and are implemented using a multitude of services with tight latency requirements. These characteristics render ineffective existing energy conserving techniques when processors are idle due to the long transition time from a deep idle power state (C-state). While prior works propose management techniques to mitigate this inefficiency, we tackle it at its root with AgileWatts (AW): a new deep C-state architecture optimized for datacenter server processors targeting latency-sensitive applications. AW is based on three key ideas. First, AW eliminates the latency overhead of saving/restoring the core context (i.e., micro-architectural state) when powering-off/-on the core in a deep idle power state by i) implementing medium-grained power-gates, carefully distributed across the CPU core, and ii) retaining context in the power-ungated domain. Second, AW eliminates the flush latency overhead (several tens of microseconds) of the L1/L2 caches when entering a deep idle power state by keeping L1/L2 cache content power-ungated. A minimal control logic also remains power-ungated to serve cache coherence traffic (i.e., snoops) seamlessly. AW implements sleep-mode in caches to reduce caches leakage power consumption and lowers a core voltage to the minimum operational voltage level to minimize the leakage power of the power-ungated domain. Third, using a state-of-the-art power efficient all-digital phase-locked loop (ADPLL) clock generator, AW keeps the PLL active and locked during the idle state, further cutting precious microseconds of wake-up latency at a negligible power cost. Our evaluation with an accurate simulator calibrated against an Intel Skylake server shows that AW reduces the energy consumption of Memcached by up to 71% (35% on average) with up to 1% performance degradation.

cs.AR↗