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Ye Zhao

Publications and source records attributed to Ye Zhao.

88 records · Page 5Linked to original sources

Local vaccination and systemic tumor suppression via irradiation and manganese adjuvant in mice

Presently 4T-1 luc cells were irradiated with proton under ultra-high dose rate FLASH or with gamma-ray with conventional dose rate, and then subcutaneous vaccination with or without Mn immuno-enhancing adjuvant into the mice for three times. One week later, we injected untreated 4T-1 luc cells on the other side of the vaccinated mice, and found that the untreated 4T-1 luc cells injected later nearly totally did not grow tumor (1/17) while controls without previous vaccination all grow tumors (18/18). The result is very interesting and the findings may help to explore in situ tumor vaccination as well as new combined radiotherapy strategies to effectively ablate primary and disseminated tumors. To our limited knowledge, this is the first paper reporting the high efficiency induction of systemic vaccination suppressing the metastasized/disseminated tumor progression.

physics.med-ph↗

SyDeBO: Symbolic-Decision-Embedded Bilevel Optimization for Long-Horizon Manipulation in Dynamic Environments

This study proposes a Task and Motion Planning (TAMP) method with symbolic decisions embedded in a bilevel optimization. This TAMP method exploits the discrete structure of sequential manipulation for long-horizon and versatile tasks in dynamically changing environments. At the symbolic planning level, we propose a scalable decision-making method for long-horizon manipulation tasks using the Planning Domain Definition Language (PDDL) with causal graph decomposition. At the motion planning level, we devise a trajectory optimization (TO) approach based on the Alternating Direction Method of Multipliers (ADMM), suitable for solving constrained, large-scale nonlinear optimization in a distributed manner. Distinct from conventional geometric motion planners, our approach generates highly dynamic manipulation motions by incorporating the full robot and object dynamics. Furthermore, in lieu of a hierarchical planning approach, we solve a holistically integrated bilevel optimization problem involving costs from both the low-level TO and the high-level search. Simulation and experimental results demonstrate dynamic manipulation for long-horizon object sorting tasks in clutter and on a moving conveyor belt.

cs.RO↗

Robust Trajectory Optimization over Uncertain Terrain with Stochastic Complementarity

Trajectory optimization with contact-rich behaviors has recently gained attention for generating diverse locomotion behaviors without pre-specified ground contact sequences. However, these approaches rely on precise models of robot dynamics and the terrain and are susceptible to uncertainty. Recent works have attempted to handle uncertainties in the system model, but few have investigated uncertainty in contact dynamics. In this study, we model uncertainty stemming from the terrain and design corresponding risk-sensitive objectives under the framework of contact-implicit trajectory optimization. In particular, we parameterize uncertainties from the terrain contact distance and friction coefficients using probability distributions and propose a corresponding expected residual minimization cost design approach. We evaluate our method in three simple robotic examples, including a legged hopping robot, and we benchmark one of our examples in simulation against a robust worst-case solution. We show that our risk-sensitive method produces contact-averse trajectories that are robust to terrain perturbations. Moreover, we demonstrate that the resulting trajectories converge to those generated by a traditional, non-robust method as the terrain model becomes more certain. Our study marks an important step towards a fully robust, contact-implicit approach suitable for deploying robots on real-world terrain.

cs.RO↗

Towards Safe Locomotion Navigation in Partially Observable Environments with Uneven Terrain

This study proposes an integrated task and motion planning method for dynamic locomotion in partially observable environments with multi-level safety guarantees. This layered planning framework is composed of a high-level symbolic task planner and a low-level phase-space motion planner. A belief abstraction at the task planning level enables belief estimation of dynamic obstacle locations and guarantees navigation safety with collision avoidance. The high-level task planner, i.e., a two-level navigation planner, employs linear temporal logic for a reactive game synthesis between the robot and its environment while incorporating low-level safe keyframe policies into formal task specification design. The synthesized task planner commands a series of locomotion actions including walking step length, step height, and heading angle changes, to the underlying keyframe decision-maker, which further determines the robot center-of-mass apex velocity keyframe. The low-level phase-space planner uses a reduced-order locomotion model to generate non-periodic trajectories meeting balancing safety criteria for straight and steering walking. These criteria are characterized by constraints on locomotion keyframe states, and are used to define keyframe transition policies via viability kernels. Simulation results of a Cassie bipedal robot designed by Agility Robotics demonstrate locomotion maneuvering in a three-dimensional, partially observable environment consisting of dynamic obstacles and uneven terrain.

cs.RO↗

Interactive Visual Study of Multiple Attributes Learning Model of X-Ray Scattering Images

Existing interactive visualization tools for deep learning are mostly applied to the training, debugging, and refinement of neural network models working on natural images. However, visual analytics tools are lacking for the specific application of x-ray image classification with multiple structural attributes. In this paper, we present an interactive system for domain scientists to visually study the multiple attributes learning models applied to x-ray scattering images. It allows domain scientists to interactively explore this important type of scientific images in embedded spaces that are defined on the model prediction output, the actual labels, and the discovered feature space of neural networks. Users are allowed to flexibly select instance images, their clusters, and compare them regarding the specified visual representation of attributes. The exploration is guided by the manifestation of model performance related to mutual relationships among attributes, which often affect the learning accuracy and effectiveness. The system thus supports domain scientists to improve the training dataset and model, find questionable attributes labels, and identify outlier images or spurious data clusters. Case studies and scientists feedback demonstrate its functionalities and usefulness.

cs.CV↗

Simultaneous Trajectory Optimization and Force Control with Soft Contact Mechanics

Force modulation of robotic manipulators has been extensively studied for several decades but is not yet commonly used in safety-critical applications due to a lack of accurate interaction contact modeling and weak performance guarantees - a large proportion of them concerning the modulation of interaction forces. This study presents a high-level framework for simultaneous trajectory optimization and force control of the interaction between manipulator and soft environments. Sliding friction and normal contact force are taken into account. The dynamics of the soft contact model and the manipulator dynamics are simultaneously incorporated in the trajectory optimizer to generate desired motion and force profiles. A constraint optimization framework based on Differential Dynamic Programming and Alternative Direction Method of Multipliers has been employed to generate optimal control input and high-dimensional state trajectories. Experimental validation of the model performance is conducted on a soft substrate with known material properties using Cartesian space force control mode. Results show a comparison of ground truth and predicted model based contact force states for a few cartesian motions and the validity range of the friction model. Potential applications include high-level task planning of medical tasks involving manipulation of compliant, delicate, and deformable tissues.

cs.RO↗

Accelerated ADMM based Trajectory Optimization for Legged Locomotion with Coupled Rigid Body Dynamics

Trajectory optimization is becoming increasingly powerful in addressing motion planning problems of underactuated robotic systems. Numerous prior studies solve such a class of large non-convex optimal control problems in a hierarchical fashion. However, numerical accuracy issues are prone to occur when one uses a full-order model to track reference trajectories generated from a reduced-order model. This study investigates an approach of Alternating Direction Method of Multipliers (ADMM) and proposes a new splitting scheme for legged locomotion problems. Rigid body dynamics constraints and other general constraints such as box and cone constraints are decomposed to multiple sub-problems in a principled manner. The resulting multi-block ADMM framework enables us to leverage the efficiency of an unconstrained optimization method--Differential Dynamical Programming--to iteratively solve the optimizations using centroidal and whole-body models. Furthermore, we propose a Stage-wise Accelerated ADMM with over-relaxation and varying-penalty schemes to improve the overall convergence rate. We evaluate and validate the performance of the proposed ADMM algorithm on a car-parking example and a bipedal locomotion problem over rough terrains.

cs.RO↗

A Natural-language-based Visual Query Approach of Uncertain Human Trajectories

Visual querying is essential for interactively exploring massive trajectory data. However, the data uncertainty imposes profound challenges to fulfill advanced analytics requirements. On the one hand, many underlying data does not contain accurate geographic coordinates, e.g., positions of a mobile phone only refer to the regions (i.e., mobile cell stations) in which it resides, instead of accurate GPS coordinates. On the other hand, domain experts and general users prefer a natural way, such as using a natural language sentence, to access and analyze massive movement data. In this paper, we propose a visual analytics approach that can extract spatial-temporal constraints from a textual sentence and support an effective query method over uncertain mobile trajectory data. It is built up on encoding massive, spatially uncertain trajectories by the semantic information of the POIs and regions covered by them, and then storing the trajectory documents in text database with an effective indexing scheme. The visual interface facilitates query condition specification, situation-aware visualization, and semantic exploration of large trajectory data. Usage scenarios on real-world human mobility datasets demonstrate the effectiveness of our approach.

cs.HC↗

Visual Understanding of Multiple Attributes Learning Model of X-Ray Scattering Images

This extended abstract presents a visualization system, which is designed for domain scientists to visually understand their deep learning model of extracting multiple attributes in x-ray scattering images. The system focuses on studying the model behaviors related to multiple structural attributes. It allows users to explore the images in the feature space, the classification output of different attributes, with respect to the actual attributes labelled by domain scientists. Abundant interactions allow users to flexibly select instance images, their clusters, and compare them visually in details. Two preliminary case studies demonstrate its functionalities and usefulness.

cs.LG↗

Distributed Impedance Control of Latency-Prone Robotic Systems with Series Elastic Actuation

Robotic systems are increasingly relying on distributed feedback controllers to tackle complex and latency-prone sensing and decision problems. These demands come at the cost of a growing computational burden and, as a result, larger controller latencies. To maximize robustness to mechanical disturbances and achieve high control performance, we emphasize the necessity for executing damping feedback in close proximity to the control plant while allocating stiffness feedback in a latency-prone centralized control process. Additionally, series elastic actuators (SEAs) are becoming prevalent in torque-controlled robots during recent years to achieve compliant interactions with environments and humans. However, designing optimal impedance controllers and characterizing impedance performance for SEAs with time delays and filtering are still under-explored problems. The presented study addresses the optimal controller design problem by devising a critically-damped gain design method for a class of SEA cascaded control architectures, which is composed of outer-impedance and inner-torque feedback loops. Via the proposed controller design criterion, we adopt frequency-domain methods to thoroughly analyze the effects of time delays, filtering and load inertia on SEA impedance performance. These results are further validated through the analysis, simulation, and experimental testing on high-performance actuators and on an omnidirectional mobile base.

cs.RO↗

Robust Optimal Planning and Control of Non-Periodic Bipedal Locomotion with A Centroidal Momentum Model

This study presents a theoretical method for planning and controlling agile bipedal locomotion based on robustly tracking a set of non-periodic keyframe states. Based on centroidal momentum dynamics, we formulate a hybrid phase-space planning and control method which includes the following key components: (i) a step transition solver that enables dynamically tracking non-periodic keyframe states over various types of terrains, (ii) a robust hybrid automaton to effectively formulate planning and control algorithms, (iii) a steering direction model to control the robot's heading, (iv) a phase-space metric to measure distance to the planned locomotion manifolds, and (v) a hybrid control method based on the previous distance metric to produce robust dynamic locomotion under external disturbances. Compared to other locomotion methodologies, we have a large focus on non-periodic gait generation and robustness metrics to deal with disturbances. Such focus enables the proposed control method to robustly track non-periodic keyframe states over various challenging terrains and under external disturbances as illustrated through several simulations.

cs.RO↗

UrbanFACET: Visually Profiling Cities from Mobile Device Recorded Movement Data of Millions of City Residents

Cities are living systems where urban infrastructures and their functions are defined and evolved due to population behaviors. Profiling the cities and functional regions has been an important topic in urban design and planning. This paper studies a unique big data set which includes daily movement data of tens of millions of city residents, and develop a visual analytics system, namely UrbanFACET, to discover and visualize the dynamical profiles of multiple cities and their residents. This big user movement data set, acquired from mobile users' agnostic check-ins at thousands of phone APPs, is well utilized in an integrative study and visualization together with urban structure (e.g., road network) and POI (Point of Interest) distributions. In particular, we novelly develop a set of information-theory based metrics to characterize the mobility patterns of city areas and groups of residents. These multifaceted metrics including Fluidity, vibrAncy, Commutation, divErsity, and densiTy (FACET) which categorize and manifest hidden urban functions and behaviors. UrbanFACET system further allows users to visually analyze and compare the metrics over different areas and cities in metropolitan scales. The system is evaluated through both case studies on several big and heavily populated cities, and user studies involving real-world users.

cs.SI↗

A Planning and Control Framework for Humanoid Systems: Robust, Optimal, and Real-time Performance

Humanoid robots are increasingly demanded to operate in interactive and human-surrounded environments while achieving sophisticated locomotion and manipulation tasks. To accomplish these tasks, roboticists unremittingly seek for advanced methods that generate whole-body coordination behaviors and meanwhile fulfill various planning and control objectives. Undoubtedly, these goals pose fundamental challenges to the robotics and control community. To take an incremental step towards reducing the performance gap between theoretical foundations and real implementations, we present a planning and control framework for the humanoid, especially legged robots, for achieving high performance and generating agile motions. A particular concentration is on the robust, optimal and real-time performance. This framework constitutes three hierarchical layers: First, we present a robust optimal phase-space planning framework for dynamic legged locomotion over rough terrain. This framework is a hybrid motion planner incorporating a series of pivotal components. Second, we take a step toward formally synthesizing high-level reactive planners for whole-body locomotion in constrained environments. We formulate a two-player temporal logic game between the contact planner and its possibly-adversarial environment. Third, we propose a distributed control architecture for the latency-prone humanoid robotic systems. A central experimental phenomenon is observed that the stability of high impedance distributed controllers is highly sensitive to damping feedback delay but much less to stiffness feedback delay. We pursue a detailed analysis of the distributed controllers where damping feedback effort is executed in proximity to the control plant, and stiffness feedback effort is implemented in a latency-prone centralized control process.

cs.RO↗

A Framework for Planning and Controlling Non-Periodic Bipedal Locomotion

This study presents a theoretical framework for planning and controlling agile bipedal locomotion based on robustly tracking a set of non-periodic apex states. Based on the prismatic inverted pendulum model, we formulate a hybrid phase-space planning and control framework which includes the following key components: (1) a step transition solver that enables dynamically tracking non-periodic apex or keyframe states over various types of terrains, (2) a robust hybrid automaton to effectively formulate planning and control algorithms, (3) a phase-space metric to measure distance to the planned locomotion manifolds, and (4) a hybrid control method based on the previous distance metric to produce robust dynamic locomotion under external disturbances. Compared to other locomotion frameworks, we have a larger focus on non-periodic gait generation and robustness metrics to deal with disturbances. Such focus enables the proposed control framework to robustly track non-periodic apex states over various challenging terrains and under external disturbances as illustrated through several simulations. Additionally, it allows a bipedal robot to perform non-periodic bouncing maneuvers over disjointed terrains.

cs.RO↗

Stability and Performance Limits of Latency-Prone Distributed Feedback Controllers

Robotic control systems are increasingly relying on distributed feedback controllers to tackle complex sensing and decision problems such as those found in highly articulated human-centered robots. These demands come at the cost of a growing computational burden and, as a result, larger controller latencies. To maximize robustness to mechanical disturbances by maximizing control feedback gains, this paper emphasizes the necessity for compromise between high- and low-level feedback control effort in distributed controllers. Specifically, the effect of distributed impedance controllers is studied where damping feedback effort is executed in close proximity to the control plant and stiffness feedback effort is executed in a latency-prone centralized control process. A central observation is that the stability of high impedance distributed controllers is very sensitive to damping feedback delay but much less to stiffness feedback delay. This study pursues a detailed analysis of this observation that leads to a physical understanding of the disparity. Then a practical controller breakdown gain rule is derived to aim at enabling control designers to consider the benefits of implementing their control applications in a distributed fashion. These considerations are further validated through the analysis, simulation and experimental testing on high performance actuators and on an omnidirectional mobile base.

eess.SY↗

Assessing Whole-Body Operational Space Control in a Point-Foot Series Elastic Biped: Balance on Split Terrain and Undirected Walking

In this paper we present advancements in control and trajectory generation for agile behavior in bipedal robots. We demonstrate that Whole-Body Operational Space Control (WBOSC), developed a few years ago, is well suited for achieving two types of agile behaviors, namely, balancing on a high pitch split terrain and achieving undirected walking on flat terrain. The work presented here is the first implementation of WBOSC on a biped robot, and more specifically a biped robot with series elastic actuators. We present and analyze a new algorithm that dynamically balances point foot robots by choosing footstep placements. Dealing with the naturally unstable dynamics of these type of systems is a difficult problem that requires both the controller and the trajectory generation algorithm to operate quickly and efficiently. We put forth a comprehensive development and integration effort: the design and construction of the biped system and experimental infrastructure, a customization of WBOSC for the agile behaviors, and new trajectory generation algorithms. Using this custom built controller, we conduct, for first time, an experiment in which a biped robot balances in a high pitch split terrain, demonstrating our ability to precisely regulate internal forces using force sensing feedback techniques. Finally, we demonstrate the stabilizing capabilities of our online trajectory generation algorithm in the physics-based simulator and through physical experiments with a planarized locomotion setup.

cs.RO↗