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Yi Su

Publications and source records attributed to Yi Su.

At least 55 records · Page 3Linked to original sources

Plasma-CycleGAN: Plasma Biomarker-Guided MRI to PET Cross-modality Translation Using Conditional CycleGAN

Cross-modality translation between MRI and PET imaging is challenging due to the distinct mechanisms underlying these modalities. Blood-based biomarkers (BBBMs) are revolutionizing Alzheimer's disease (AD) detection by identifying patients and quantifying brain amyloid levels. However, the potential of BBBMs to enhance PET image synthesis remains unexplored. In this paper, we performed a thorough study on the effect of incorporating BBBM into deep generative models. By evaluating three widely used cross-modality translation models, we found that BBBMs integration consistently enhances the generative quality across all models. By visual inspection of the generated results, we observed that PET images generated by CycleGAN exhibit the best visual fidelity. Based on these findings, we propose Plasma-CycleGAN, a novel generative model based on CycleGAN, to synthesize PET images from MRI using BBBMs as conditions. This is the first approach to integrate BBBMs in conditional cross-modality translation between MRI and PET.

cs.CV↗

Compressed Domain Prior-Guided Video Super-Resolution for Cloud Gaming Content

Cloud gaming is an advanced form of Internet service that necessitates local terminals to decode within limited resources and time latency. Super-Resolution (SR) techniques are often employed on these terminals as an efficient way to reduce the required bit-rate bandwidth for cloud gaming. However, insufficient attention has been paid to SR of compressed game video content. Most SR networks amplify block artifacts and ringing effects in decoded frames while ignoring edge details of game content, leading to unsatisfactory reconstruction results. In this paper, we propose a novel lightweight network called Coding Prior-Guided Super-Resolution (CPGSR) to address the SR challenges in compressed game video content. First, we design a Compressed Domain Guided Block (CDGB) to extract features of different depths from coding priors, which are subsequently integrated with features from the U-net backbone. Then, a series of re-parameterization blocks are utilized for reconstruction. Ultimately, inspired by the quantization in video coding, we propose a partitioned focal frequency loss to effectively guide the model's focus on preserving high-frequency information. Extensive experiments demonstrate the advancement of our approach.

eess.IV↗

AutoGFI: Streamlined Generalized Fiducial Inference for Modern Inference Problems in Models with Additive Errors

The concept of fiducial inference was introduced by R. A. Fisher in the 1930s to address the perceived limitations of Bayesian inference, particularly the need for subjective prior distributions in cases with limited prior information. However, Fisher's fiducial approach lost favor due to complications, especially in multi-parameter problems. With renewed interest in fiducial inference in the 2000s, generalized fiducial inference (GFI) emerged as a promising extension of Fisher's ideas, offering new solutions for complex inference challenges. Despite its potential, GFI's adoption has been hindered by demanding mathematical derivations and complex implementation requirements, such as Markov Chain Monte Carlo (MCMC) algorithms. This paper introduces AutoGFI, a streamlined variant of GFI designed to simplify its application across various inference problems with additive noise. AutoGFI's accessibility lies in its simplicity-requiring only a fitting routine-making it a feasible option for a wider range of researchers and practitioners. To demonstrate its efficacy, AutoGFI is applied to three challenging problems: tensor regression, matrix completion, and network cohesion regression. These case studies showcase AutoGFI's competitive performance against specialized solutions, highlighting its potential to broaden the application of GFI in practical domains, ultimately enriching the statistical inference toolkit.

stat.ME↗

AudioCIL: A Python Toolbox for Audio Class-Incremental Learning with Multiple Scenes

Deep learning, with its robust aotomatic feature extraction capabilities, has demonstrated significant success in audio signal processing. Typically, these methods rely on static, pre-collected large-scale datasets for training, performing well on a fixed number of classes. However, the real world is characterized by constant change, with new audio classes emerging from streaming or temporary availability due to privacy. This dynamic nature of audio environments necessitates models that can incrementally learn new knowledge for new classes without discarding existing information. Introducing incremental learning to the field of audio signal processing, i.e., Audio Class-Incremental Learning (AuCIL), is a meaningful endeavor. We propose such a toolbox named AudioCIL to align audio signal processing algorithms with real-world scenarios and strengthen research in audio class-incremental learning. Code is available at https://github.com/colaudiolab/AudioCIL.

cs.SD↗

Device-Directed Speech Detection for Follow-up Conversations Using Large Language Models

Follow-up conversations with virtual assistants (VAs) enable a user to seamlessly interact with a VA without the need to repeatedly invoke it using a keyword (after the first query). Therefore, accurate Device-directed Speech Detection (DDSD) from the follow-up queries is critical for enabling naturalistic user experience. To this end, we explore the notion of Large Language Models (LLMs) and model the first query when making inference about the follow-ups (based on the ASR-decoded text), via prompting of a pretrained LLM, or by adapting a binary classifier on top of the LLM. In doing so, we also exploit the ASR uncertainty when designing the LLM prompts. We show on the real-world dataset of follow-up conversations that this approach yields large gains (20-40% reduction in false alarms at 10% fixed false rejects) due to the joint modeling of the previous speech context and ASR uncertainty, compared to when follow-ups are modeled alone.

eess.AS↗

TPOT: Topology Preserving Optimal Transport in Retinal Fundus Image Enhancement

Retinal fundus photography enhancement is important for diagnosing and monitoring retinal diseases. However, early approaches to retinal image enhancement, such as those based on Generative Adversarial Networks (GANs), often struggle to preserve the complex topological information of blood vessels, resulting in spurious or missing vessel structures. The persistence diagram, which captures topological features based on the persistence of topological structures under different filtrations, provides a promising way to represent the structure information. In this work, we propose a topology-preserving training paradigm that regularizes blood vessel structures by minimizing the differences of persistence diagrams. We call the resulting framework Topology Preserving Optimal Transport (TPOT). Experimental results on a large-scale dataset demonstrate the superiority of the proposed method compared to several state-of-the-art supervised and unsupervised techniques, both in terms of image quality and performance in the downstream blood vessel segmentation task. The code is available at https://github.com/Retinal-Research/TPOT.

eess.IV↗

Online Feature Updates Improve Online (Generalized) Label Shift Adaptation

This paper addresses the prevalent issue of label shift in an online setting with missing labels, where data distributions change over time and obtaining timely labels is challenging. While existing methods primarily focus on adjusting or updating the final layer of a pre-trained classifier, we explore the untapped potential of enhancing feature representations using unlabeled data at test-time. Our novel method, Online Label Shift adaptation with Online Feature Updates (OLS-OFU), leverages self-supervised learning to refine the feature extraction process, thereby improving the prediction model. By carefully designing the algorithm, theoretically OLS-OFU maintains the similar online regret convergence to the results in the literature while taking the improved features into account. Empirically, it achieves substantial improvements over existing methods, which is as significant as the gains existing methods have over the baseline (i.e., without distribution shift adaptations).

cs.LG↗

Training Language Models to Self-Correct via Reinforcement Learning

Self-correction is a highly desirable capability of large language models (LLMs), yet it has consistently been found to be largely ineffective in modern LLMs. Current methods for training self-correction typically depend on either multiple models, a more advanced model, or additional forms of supervision. To address these shortcomings, we develop a multi-turn online reinforcement learning (RL) approach, SCoRe, that significantly improves an LLM's self-correction ability using entirely self-generated data. To build SCoRe, we first show that variants of supervised fine-tuning (SFT) on offline model-generated correction traces are often insufficient for instilling self-correction behavior. In particular, we observe that training via SFT falls prey to either a distribution mismatch between mistakes made by the data-collection policy and the model's own responses, or to behavior collapse, where learning implicitly prefers only a certain mode of correction behavior that is often not effective at self-correction on test problems. SCoRe addresses these challenges by training under the model's own distribution of self-generated correction traces and using appropriate regularization to steer the learning process into learning a self-correction behavior that is effective at test time as opposed to fitting high-reward responses for a given prompt. This regularization process includes an initial phase of multi-turn RL on a base model to generate a policy initialization that is less susceptible to collapse, followed by using a reward bonus to amplify self-correction. With Gemini 1.0 Pro and 1.5 Flash models, we find that SCoRe achieves state-of-the-art self-correction performance, improving the base models' self-correction by 15.6% and 9.1% respectively on MATH and HumanEval.

cs.LG↗

Supervised Multi-Modal Fission Learning

Learning from multimodal datasets can leverage complementary information and improve performance in prediction tasks. A commonly used strategy to account for feature correlations in high-dimensional datasets is the latent variable approach. Several latent variable methods have been proposed for multimodal datasets. However, these methods either focus on extracting the shared component across all modalities or on extracting both a shared component and individual components specific to each modality. To address this gap, we propose a Multi-Modal Fission Learning (MMFL) model that simultaneously identifies globally joint, partially joint, and individual components underlying the features of multimodal datasets. Unlike existing latent variable methods, MMFL uses supervision from the response variable to identify predictive latent components and has a natural extension for incorporating incomplete multimodal data. Through simulation studies, we demonstrate that MMFL outperforms various existing multimodal algorithms in both complete and incomplete modality settings. We applied MMFL to a real-world case study for early prediction of Alzheimers Disease using multimodal neuroimaging and genomics data from the Alzheimers Disease Neuroimaging Initiative (ADNI) dataset. MMFL provided more accurate predictions and better insights into within- and across-modality correlations compared to existing methods.

cs.LG↗

CUNSB-RFIE: Context-aware Unpaired Neural Schrödinger Bridge in Retinal Fundus Image Enhancement

Retinal fundus photography is significant in diagnosing and monitoring retinal diseases. However, systemic imperfections and operator/patient-related factors can hinder the acquisition of high-quality retinal images. Previous efforts in retinal image enhancement primarily relied on GANs, which are limited by the trade-off between training stability and output diversity. In contrast, the Schrödinger Bridge (SB), offers a more stable solution by utilizing Optimal Transport (OT) theory to model a stochastic differential equation (SDE) between two arbitrary distributions. This allows SB to effectively transform low-quality retinal images into their high-quality counterparts. In this work, we leverage the SB framework to propose an image-to-image translation pipeline for retinal image enhancement. Additionally, previous methods often fail to capture fine structural details, such as blood vessels. To address this, we enhance our pipeline by introducing Dynamic Snake Convolution, whose tortuous receptive field can better preserve tubular structures. We name the resulting retinal fundus image enhancement framework the Context-aware Unpaired Neural Schrödinger Bridge (CUNSB-RFIE). To the best of our knowledge, this is the first endeavor to use the SB approach for retinal image enhancement. Experimental results on a large-scale dataset demonstrate the advantage of the proposed method compared to several state-of-the-art supervised and unsupervised methods in terms of image quality and performance on downstream tasks.The code is available at https://github.com/Retinal-Research/CUNSB-RFIE .

eess.IV↗

KGLens: Towards Efficient and Effective Knowledge Probing of Large Language Models with Knowledge Graphs

Large Language Models (LLMs) might hallucinate facts, while curated Knowledge Graph (KGs) are typically factually reliable especially with domain-specific knowledge. Measuring the alignment between KGs and LLMs can effectively probe the factualness and identify the knowledge blind spots of LLMs. However, verifying the LLMs over extensive KGs can be expensive. In this paper, we present KGLens, a Thompson-sampling-inspired framework aimed at effectively and efficiently measuring the alignment between KGs and LLMs. KGLens features a graph-guided question generator for converting KGs into natural language, along with a carefully designed importance sampling strategy based on parameterized KG structure to expedite KG traversal. Our simulation experiment compares the brute force method with KGLens under six different sampling methods, demonstrating that our approach achieves superior probing efficiency. Leveraging KGLens, we conducted in-depth analyses of the factual accuracy of ten LLMs across three large domain-specific KGs from Wikidata, composing over 19K edges, 700 relations, and 21K entities. Human evaluation results indicate that KGLens can assess LLMs with a level of accuracy nearly equivalent to that of human annotators, achieving 95.7% of the accuracy rate.

cs.AI↗

Demonstration Augmentation for Zero-shot In-context Learning

Large Language Models (LLMs) have demonstrated an impressive capability known as In-context Learning (ICL), which enables them to acquire knowledge from textual demonstrations without the need for parameter updates. However, many studies have highlighted that the model's performance is sensitive to the choice of demonstrations, presenting a significant challenge for practical applications where we lack prior knowledge of user queries. Consequently, we need to construct an extensive demonstration pool and incorporate external databases to assist the model, leading to considerable time and financial costs. In light of this, some recent research has shifted focus towards zero-shot ICL, aiming to reduce the model's reliance on external information by leveraging their inherent generative capabilities. Despite the effectiveness of these approaches, the content generated by the model may be unreliable, and the generation process is time-consuming. To address these issues, we propose Demonstration Augmentation for In-context Learning (DAIL), which employs the model's previously predicted historical samples as demonstrations for subsequent ones. DAIL brings no additional inference cost and does not rely on the model's generative capabilities. Our experiments reveal that DAIL can significantly improve the model's performance over direct zero-shot inference and can even outperform few-shot ICL without any external information.

cs.CL↗

OpenBA-V2: Reaching 77.3% High Compression Ratio with Fast Multi-Stage Pruning

Large Language Models (LLMs) have played an important role in many fields due to their powerful capabilities.However, their massive number of parameters leads to high deployment requirements and incurs significant inference costs, which impedes their practical applications. Training smaller models is an effective way to address this problem. Therefore, we introduce OpenBA-V2, a 3.4B model derived from multi-stage compression and continual pre-training from the original 15B OpenBA model. OpenBA-V2 utilizes more data, more flexible training objectives, and techniques such as layer pruning, neural pruning, and vocabulary pruning to achieve a compression rate of 77.3\% with minimal performance loss. OpenBA-V2 demonstrates competitive performance compared to other open-source models of similar size, achieving results close to or on par with the 15B OpenBA model in downstream tasks such as common sense reasoning and Named Entity Recognition (NER). OpenBA-V2 illustrates that LLMs can be compressed into smaller ones with minimal performance loss by employing advanced training objectives and data strategies, which may help deploy LLMs in resource-limited scenarios.

cs.CL↗

Ordinal Classification with Distance Regularization for Robust Brain Age Prediction

Age is one of the major known risk factors for Alzheimer's Disease (AD). Detecting AD early is crucial for effective treatment and preventing irreversible brain damage. Brain age, a measure derived from brain imaging reflecting structural changes due to aging, may have the potential to identify AD onset, assess disease risk, and plan targeted interventions. Deep learning-based regression techniques to predict brain age from magnetic resonance imaging (MRI) scans have shown great accuracy recently. However, these methods are subject to an inherent regression to the mean effect, which causes a systematic bias resulting in an overestimation of brain age in young subjects and underestimation in old subjects. This weakens the reliability of predicted brain age as a valid biomarker for downstream clinical applications. Here, we reformulate the brain age prediction task from regression to classification to address the issue of systematic bias. Recognizing the importance of preserving ordinal information from ages to understand aging trajectory and monitor aging longitudinally, we propose a novel ORdinal Distance Encoded Regularization (ORDER) loss that incorporates the order of age labels, enhancing the model's ability to capture age-related patterns. Extensive experiments and ablation studies demonstrate that this framework reduces systematic bias, outperforms state-of-art methods by statistically significant margins, and can better capture subtle differences between clinical groups in an independent AD dataset. Our implementation is publicly available at https://github.com/jaygshah/Robust-Brain-Age-Prediction.

eess.IV↗

High-temperature superconductivity with zero-resistance and strange metal behavior in La$_{3}$Ni$_{2}$O$_{7-δ}$

Recently signatures of superconductivity were observed close to 80 K in \LN\ under pressure. This discovery positions \LN\ as the first bulk nickelate with high-temperature superconductivity, but the lack of zero resistance presents a significant drawback for validating the findings. Here we report pressure measurements up to over 30 GPa using a liquid pressure medium and show that single crystals of \LNO\ do exhibit zero resistance. We find that \LNO\ remains metallic under applied pressures, suggesting the absence of a metal-insulator transition proximate to the superconductivity. Analysis of the normal state $T$-linear resistance suggests an intricate link between this strange metal behaviour and superconductivity, whereby at high pressures both the linear resistance coefficient and superconducting transition are slowly suppressed by pressure, while at intermediate pressures both the superconductivity and strange metal behaviour appear disrupted, possibly due to a nearby structural instability. The association between strange metal behaviour and high-temperature superconductivity is very much in line with diverse classes of unconventional superconductors, including the cuprates and Fe-based superconductors. Understanding the superconductivity of \LNO\ evidently requires further revealing the interplay of strange metal behaviour, superconductivity, as well as possible competing electronic or structural phases.

cond-mat.supr-con↗

Long-Term Value of Exploration: Measurements, Findings and Algorithms

Effective exploration is believed to positively influence the long-term user experience on recommendation platforms. Determining its exact benefits, however, has been challenging. Regular A/B tests on exploration often measure neutral or even negative engagement metrics while failing to capture its long-term benefits. We here introduce new experiment designs to formally quantify the long-term value of exploration by examining its effects on content corpus, and connecting content corpus growth to the long-term user experience from real-world experiments. Once established the values of exploration, we investigate the Neural Linear Bandit algorithm as a general framework to introduce exploration into any deep learning based ranking systems. We conduct live experiments on one of the largest short-form video recommendation platforms that serves billions of users to validate the new experiment designs, quantify the long-term values of exploration, and to verify the effectiveness of the adopted neural linear bandit algorithm for exploration.

cs.IR↗

A Novel Hybrid Ordinal Learning Model with Health Care Application

Ordinal learning (OL) is a type of machine learning models with broad utility in health care applications such as diagnosis of different grades of a disease (e.g., mild, modest, severe) and prediction of the speed of disease progression (e.g., very fast, fast, moderate, slow). This paper aims to tackle a situation when precisely labeled samples are limited in the training set due to cost or availability constraints, whereas there could be an abundance of samples with imprecise labels. We focus on imprecise labels that are intervals, i.e., one can know that a sample belongs to an interval of labels but cannot know which unique label it has. This situation is quite common in health care datasets due to limitations of the diagnostic instrument, sparse clinical visits, or/and patient dropout. Limited research has been done to develop OL models with imprecise/interval labels. We propose a new Hybrid Ordinal Learner (HOL) to integrate samples with both precise and interval labels to train a robust OL model. We also develop a tractable and efficient optimization algorithm to solve the HOL formulation. We compare HOL with several recently developed OL methods on four benchmarking datasets, which demonstrate the superior performance of HOL. Finally, we apply HOL to a real-world dataset for predicting the speed of progressing to Alzheimer's Disease (AD) for individuals with Mild Cognitive Impairment (MCI) based on a combination of multi-modality neuroimaging and demographic/clinical datasets. HOL achieves high accuracy in the prediction and outperforms existing methods. The capability of accurately predicting the speed of progression to AD for each individual with MCI has the potential for helping facilitate more individually-optimized interventional strategies.

cs.LG↗

Unified Off-Policy Learning to Rank: a Reinforcement Learning Perspective

Off-policy Learning to Rank (LTR) aims to optimize a ranker from data collected by a deployed logging policy. However, existing off-policy learning to rank methods often make strong assumptions about how users generate the click data, i.e., the click model, and hence need to tailor their methods specifically under different click models. In this paper, we unified the ranking process under general stochastic click models as a Markov Decision Process (MDP), and the optimal ranking could be learned with offline reinforcement learning (RL) directly. Building upon this, we leverage offline RL techniques for off-policy LTR and propose the Click Model-Agnostic Unified Off-policy Learning to Rank (CUOLR) method, which could be easily applied to a wide range of click models. Through a dedicated formulation of the MDP, we show that offline RL algorithms can adapt to various click models without complex debiasing techniques and prior knowledge of the model. Results on various large-scale datasets demonstrate that CUOLR consistently outperforms the state-of-the-art off-policy learning to rank algorithms while maintaining consistency and robustness under different click models.

cs.LG↗