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Yihao Liu

Publications and source records attributed to Yihao Liu.

At least 91 records · Page 5Linked to original sources

Glioma Multimodal MRI Analysis System for Tumor Layered Diagnosis via Multi-task Semi-supervised Learning

Gliomas are the most common primary tumors of the central nervous system. Multimodal MRI is widely used for the preliminary screening of gliomas and plays a crucial role in auxiliary diagnosis, therapeutic efficacy, and prognostic evaluation. Currently, the computer-aided diagnostic studies of gliomas using MRI have focused on independent analysis events such as tumor segmentation, grading, and radiogenomic classification, without studying inter-dependencies among these events. In this study, we propose a Glioma Multimodal MRI Analysis System (GMMAS) that utilizes a deep learning network for processing multiple events simultaneously, leveraging their inter-dependencies through an uncertainty-based multi-task learning architecture and synchronously outputting tumor region segmentation, glioma histological subtype, IDH mutation genotype, and 1p/19q chromosome disorder status. Compared with the reported single-task analysis models, GMMAS improves the precision across tumor layered diagnostic tasks. Additionally, we have employed a two-stage semi-supervised learning method, enhancing model performance by fully exploiting both labeled and unlabeled MRI samples. Further, by utilizing an adaptation module based on knowledge self-distillation and contrastive learning for cross-modal feature extraction, GMMAS exhibited robustness in situations of modality absence and revealed the differing significance of each MRI modal. Finally, based on the analysis outputs of the GMMAS, we created a visual and user-friendly platform for doctors and patients, introducing GMMAS-GPT to generate personalized prognosis evaluations and suggestions.

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Correlation Ratio for Unsupervised Learning of Multi-modal Deformable Registration

In recent years, unsupervised learning for deformable image registration has been a major research focus. This approach involves training a registration network using pairs of moving and fixed images, along with a loss function that combines an image similarity measure and deformation regularization. For multi-modal image registration tasks, the correlation ratio has been a widely-used image similarity measure historically, yet it has been underexplored in current deep learning methods. Here, we propose a differentiable correlation ratio to use as a loss function for learning-based multi-modal deformable image registration. This approach extends the traditionally non-differentiable implementation of the correlation ratio by using the Parzen windowing approximation, enabling backpropagation with deep neural networks. We validated the proposed correlation ratio on a multi-modal neuroimaging dataset. In addition, we established a Bayesian training framework to study how the trade-off between the deformation regularizer and similarity measures, including mutual information and our proposed correlation ratio, affects the registration performance.

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TablePilot: Recommending Human-Preferred Tabular Data Analysis with Large Language Models

Tabular data analysis is crucial in many scenarios, yet efficiently identifying the most relevant data analysis queries and results for a new table remains a significant challenge. The complexity of tabular data, diverse analytical operations, and the demand for high-quality analysis make the process tedious. To address these challenges, we aim to recommend query-code-result triplets tailored for new tables in tabular data analysis workflows. In this paper, we present TablePilot, a pioneering tabular data analysis framework leveraging large language models to autonomously generate comprehensive and superior analytical results without relying on user profiles or prior interactions. The framework incorporates key designs in analysis preparation and analysis optimization to enhance accuracy. Additionally, we propose Rec-Align, a novel method to further improve recommendation quality and better align with human preferences. Experiments on DART, a dataset specifically designed for comprehensive tabular data analysis recommendation, demonstrate the effectiveness of our framework. Based on GPT-4o, the tuned TablePilot achieves 77.0% top-5 recommendation recall. Human evaluations further highlight its effectiveness in optimizing tabular data analysis workflows.

cs.CL↗

EGVD: Event-Guided Video Diffusion Model for Physically Realistic Large-Motion Frame Interpolation

Video frame interpolation (VFI) in scenarios with large motion remains challenging due to motion ambiguity between frames. While event cameras can capture high temporal resolution motion information, existing event-based VFI methods struggle with limited training data and complex motion patterns. In this paper, we introduce Event-Guided Video Diffusion Model (EGVD), a novel framework that leverages the powerful priors of pre-trained stable video diffusion models alongside the precise temporal information from event cameras. Our approach features a Multi-modal Motion Condition Generator (MMCG) that effectively integrates RGB frames and event signals to guide the diffusion process, producing physically realistic intermediate frames. We employ a selective fine-tuning strategy that preserves spatial modeling capabilities while efficiently incorporating event-guided temporal information. We incorporate input-output normalization techniques inspired by recent advances in diffusion modeling to enhance training stability across varying noise levels. To improve generalization, we construct a comprehensive dataset combining both real and simulated event data across diverse scenarios. Extensive experiments on both real and simulated datasets demonstrate that EGVD significantly outperforms existing methods in handling large motion and challenging lighting conditions, achieving substantial improvements in perceptual quality metrics (27.4% better LPIPS on Prophesee and 24.1% on BSRGB) while maintaining competitive fidelity measures. Code and datasets available at: https://github.com/OpenImagingLab/EGVD.

cs.CV↗

DiffVSR: Revealing an Effective Recipe for Taming Robust Video Super-Resolution Against Complex Degradations

Diffusion models have demonstrated exceptional capabilities in image restoration, yet their application to video super-resolution (VSR) faces significant challenges in balancing fidelity with temporal consistency. Our evaluation reveals a critical gap: existing approaches consistently fail on severely degraded videos--precisely where diffusion models' generative capabilities are most needed. We identify that existing diffusion-based VSR methods struggle primarily because they face an overwhelming learning burden: simultaneously modeling complex degradation distributions, content representations, and temporal relationships with limited high-quality training data. To address this fundamental challenge, we present DiffVSR, featuring a Progressive Learning Strategy (PLS) that systematically decomposes this learning burden through staged training, enabling superior performance on complex degradations. Our framework additionally incorporates an Interweaved Latent Transition (ILT) technique that maintains competitive temporal consistency without additional training overhead. Experiments demonstrate that our approach excels in scenarios where competing methods struggle, particularly on severely degraded videos. Our work reveals that addressing the learning strategy, rather than focusing solely on architectural complexity, is the critical path toward robust real-world video super-resolution with diffusion models.

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Look Before You Leap: Using Serialized State Machine for Language Conditioned Robotic Manipulation

Imitation learning frameworks for robotic manipulation have drawn attention in the recent development of language model grounded robotics. However, the success of the frameworks largely depends on the coverage of the demonstration cases: When the demonstration set does not include examples of how to act in all possible situations, the action may fail and can result in cascading errors. To solve this problem, we propose a framework that uses serialized Finite State Machine (FSM) to generate demonstrations and improve the success rate in manipulation tasks requiring a long sequence of precise interactions. To validate its effectiveness, we use environmentally evolving and long-horizon puzzles that require long sequential actions. Experimental results show that our approach achieves a success rate of up to 98 in these tasks, compared to the controlled condition using existing approaches, which only had a success rate of up to 60, and, in some tasks, almost failed completely.

cs.RO↗

dARt Vinci: Egocentric Data Collection for Surgical Robot Learning at Scale

Data scarcity has long been an issue in the robot learning community. Particularly, in safety-critical domains like surgical applications, obtaining high-quality data can be especially difficult. It poses challenges to researchers seeking to exploit recent advancements in reinforcement learning and imitation learning, which have greatly improved generalizability and enabled robots to conduct tasks autonomously. We introduce dARt Vinci, a scalable data collection platform for robot learning in surgical settings. The system uses Augmented Reality (AR) hand tracking and a high-fidelity physics engine to capture subtle maneuvers in primitive surgical tasks: By eliminating the need for a physical robot setup and providing flexibility in terms of time, space, and hardware resources-such as multiview sensors and actuators-specialized simulation is a viable alternative. At the same time, AR allows the robot data collection to be more egocentric, supported by its body tracking and content overlaying capabilities. Our user study confirms the proposed system's efficiency and usability, where we use widely-used primitive tasks for training teleoperation with da Vinci surgical robots. Data throughput improves across all tasks compared to real robot settings by 41% on average. The total experiment time is reduced by an average of 10%. The temporal demand in the task load survey is improved. These gains are statistically significant. Additionally, the collected data is over 400 times smaller in size, requiring far less storage while achieving double the frequency.

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OkraLong: A Flexible Retrieval-Augmented Framework for Long-Text Query Processing

Large Language Models (LLMs) encounter challenges in efficiently processing long-text queries, as seen in applications like enterprise document analysis and financial report comprehension. While conventional solutions employ long-context processing or Retrieval-Augmented Generation (RAG), they suffer from prohibitive input expenses or incomplete information. Recent advancements adopt context compression and dynamic retrieval loops, but still sacrifice critical details or incur iterative costs. To address these limitations, we propose OkraLong, a novel framework that flexibly optimizes the entire processing workflow. Unlike prior static or coarse-grained adaptive strategies, OkraLong adopts fine-grained orchestration through three synergistic components: analyzer, organizer and executor. The analyzer characterizes the task states, which guide the organizer in dynamically scheduling the workflow. The executor carries out the execution and generates the final answer. Experimental results demonstrate that OkraLong not only enhances answer accuracy but also achieves cost-effectiveness across a variety of datasets.

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From Screens to Scenes: A Survey of Embodied AI in Healthcare

Healthcare systems worldwide face persistent challenges in efficiency, accessibility, and personalization. Powered by modern AI technologies such as multimodal large language models and world models, Embodied AI (EmAI) represents a transformative frontier, offering enhanced autonomy and the ability to interact with the physical world to address these challenges. As an interdisciplinary and rapidly evolving research domain, "EmAI in healthcare" spans diverse fields such as algorithms, robotics, and biomedicine. This complexity underscores the importance of timely reviews and analyses to track advancements, address challenges, and foster cross-disciplinary collaboration. In this paper, we provide a comprehensive overview of the "brain" of EmAI for healthcare, wherein we introduce foundational AI algorithms for perception, actuation, planning, and memory, and focus on presenting the healthcare applications spanning clinical interventions, daily care & companionship, infrastructure support, and biomedical research. Despite its promise, the development of EmAI for healthcare is hindered by critical challenges such as safety concerns, gaps between simulation platforms and real-world applications, the absence of standardized benchmarks, and uneven progress across interdisciplinary domains. We discuss the technical barriers and explore ethical considerations, offering a forward-looking perspective on the future of EmAI in healthcare. A hierarchical framework of intelligent levels for EmAI systems is also introduced to guide further development. By providing systematic insights, this work aims to inspire innovation and practical applications, paving the way for a new era of intelligent, patient-centered healthcare.

cs.AI↗

Investigating the impact of kernel harmonization and deformable registration on inspiratory and expiratory chest CT images for people with COPD

Paired inspiratory-expiratory CT scans enable the quantification of gas trapping due to small airway disease and emphysema by analyzing lung tissue motion in COPD patients. Deformable image registration of these scans assesses regional lung volumetric changes. However, variations in reconstruction kernels between paired scans introduce errors in quantitative analysis. This work proposes a two-stage pipeline to harmonize reconstruction kernels and perform deformable image registration using data acquired from the COPDGene study. We use a cycle generative adversarial network (GAN) to harmonize inspiratory scans reconstructed with a hard kernel (BONE) to match expiratory scans reconstructed with a soft kernel (STANDARD). We then deformably register the expiratory scans to inspiratory scans. We validate harmonization by measuring emphysema using a publicly available segmentation algorithm before and after harmonization. Results show harmonization significantly reduces emphysema measurement inconsistencies, decreasing median emphysema scores from 10.479% to 3.039%, with a reference median score of 1.305% from the STANDARD kernel as the target. Registration accuracy is evaluated via Dice overlap between emphysema regions on inspiratory, expiratory, and deformed images. The Dice coefficient between inspiratory emphysema masks and deformably registered emphysema masks increases significantly across registration stages (p<0.001). Additionally, we demonstrate that deformable registration is robust to kernel variations.

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Beyond the Lungs: Extending the Field of View in Chest CT with Latent Diffusion Models

The interconnection between the human lungs and other organs, such as the liver and kidneys, is crucial for understanding the underlying risks and effects of lung diseases and improving patient care. However, most research chest CT imaging is focused solely on the lungs due to considerations of cost and radiation dose. This restricted field of view (FOV) in the acquired images poses challenges to comprehensive analysis and hinders the ability to gain insights into the impact of lung diseases on other organs. To address this, we propose SCOPE (Spatial Coverage Optimization with Prior Encoding), a novel approach to capture the inter-organ relationships from CT images and extend the FOV of chest CT images. Our approach first trains a variational autoencoder (VAE) to encode 2D axial CT slices individually, then stacks the latent representations of the VAE to form a 3D context for training a latent diffusion model. Once trained, our approach extends the FOV of CT images in the z-direction by generating new axial slices in a zero-shot manner. We evaluated our approach on the National Lung Screening Trial (NLST) dataset, and results suggest that it effectively extends the FOV to include the liver and kidneys, which are not completely covered in the original NLST data acquisition. Quantitative results on a held-out whole-body dataset demonstrate that the generated slices exhibit high fidelity with acquired data, achieving an SSIM of 0.81.

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Robust Body Composition Analysis by Generating 3D CT Volumes from Limited 2D Slices

Body composition analysis provides valuable insights into aging, disease progression, and overall health conditions. Due to concerns of radiation exposure, two-dimensional (2D) single-slice computed tomography (CT) imaging has been used repeatedly for body composition analysis. However, this approach introduces significant spatial variability that can impact the accuracy and robustness of the analysis. To mitigate this issue and facilitate body composition analysis, this paper presents a novel method to generate 3D CT volumes from limited number of 2D slices using a latent diffusion model (LDM). Our approach first maps 2D slices into a latent representation space using a variational autoencoder. An LDM is then trained to capture the 3D context of a stack of these latent representations. To accurately interpolate intermediateslices and construct a full 3D volume, we utilize body part regression to determine the spatial location and distance between the acquired slices. Experiments on both in-house and public 3D abdominal CT datasets demonstrate that the proposed method significantly enhances body composition analysis compared to traditional 2D-based analysis, with a reduced error rate from 23.3% to 15.2%.

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WeatherGFM: Learning A Weather Generalist Foundation Model via In-context Learning

The Earth's weather system encompasses intricate weather data modalities and diverse weather understanding tasks, which hold significant value to human life. Existing data-driven models focus on single weather understanding tasks (e.g., weather forecasting). Although these models have achieved promising results, they fail to tackle various complex tasks within a single and unified model. Moreover, the paradigm that relies on limited real observations for a single scenario hinders the model's performance upper bound. In response to these limitations, we draw inspiration from the in-context learning paradigm employed in state-of-the-art visual foundation models and large language models. In this paper, we introduce the first generalist weather foundation model (WeatherGFM), designed to address a wide spectrum of weather understanding tasks in a unified manner. More specifically, we initially unify the representation and definition of the diverse weather understanding tasks. Subsequently, we devised weather prompt formats to manage different weather data modalities, namely single, multiple, and temporal modalities. Finally, we adopt a visual prompting question-answering paradigm for the training of unified weather understanding tasks. Extensive experiments indicate that our WeatherGFM can effectively handle up to ten weather understanding tasks, including weather forecasting, super-resolution, weather image translation, and post-processing. Our method also showcases generalization ability on unseen tasks.

cs.LG↗

A survey on deep learning in medical image registration: new technologies, uncertainty, evaluation metrics, and beyond

Deep learning technologies have dramatically reshaped the field of medical image registration over the past decade. The initial developments, such as regression-based and U-Net-based networks, established the foundation for deep learning in image registration. Subsequent progress has been made in various aspects of deep learning-based registration, including similarity measures, deformation regularizations, network architectures, and uncertainty estimation. These advancements have not only enriched the field of image registration but have also facilitated its application in a wide range of tasks, including atlas construction, multi-atlas segmentation, motion estimation, and 2D-3D registration. In this paper, we present a comprehensive overview of the most recent advancements in deep learning-based image registration. We begin with a concise introduction to the core concepts of deep learning-based image registration. Then, we delve into innovative network architectures, loss functions specific to registration, and methods for estimating registration uncertainty. Additionally, this paper explores appropriate evaluation metrics for assessing the performance of deep learning models in registration tasks. Finally, we highlight the practical applications of these novel techniques in medical imaging and discuss the future prospects of deep learning-based image registration.

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Imprompter: Tricking LLM Agents into Improper Tool Use

Large Language Model (LLM) Agents are an emerging computing paradigm that blends generative machine learning with tools such as code interpreters, web browsing, email, and more generally, external resources. These agent-based systems represent an emerging shift in personal computing. We contribute to the security foundations of agent-based systems and surface a new class of automatically computed obfuscated adversarial prompt attacks that violate the confidentiality and integrity of user resources connected to an LLM agent. We show how prompt optimization techniques can find such prompts automatically given the weights of a model. We demonstrate that such attacks transfer to production-level agents. For example, we show an information exfiltration attack on Mistral's LeChat agent that analyzes a user's conversation, picks out personally identifiable information, and formats it into a valid markdown command that results in leaking that data to the attacker's server. This attack shows a nearly 80% success rate in an end-to-end evaluation. We conduct a range of experiments to characterize the efficacy of these attacks and find that they reliably work on emerging agent-based systems like Mistral's LeChat, ChatGLM, and Meta's Llama. These attacks are multimodal, and we show variants in the text-only and image domains.

cs.CR↗

An Image-Guided Robotic System for Transcranial Magnetic Stimulation: System Development and Experimental Evaluation

Transcranial magnetic stimulation (TMS) is a noninvasive medical procedure that can modulate brain activity, and it is widely used in neuroscience and neurology research. Compared to manual operators, robots may improve the outcome of TMS due to their superior accuracy and repeatability. However, there has not been a widely accepted standard protocol for performing robotic TMS using fine-segmented brain images, resulting in arbitrary planned angles with respect to the true boundaries of the modulated cortex. Given that the recent study in TMS simulation suggests a noticeable difference in outcomes when using different anatomical details, cortical shape should play a more significant role in deciding the optimal TMS coil pose. In this work, we introduce an image-guided robotic system for TMS that focuses on (1) establishing standardized planning methods and heuristics to define a reference (true zero) for the coil poses and (2) solving the issue that the manual coil placement requires expert hand-eye coordination which often leading to low repeatability of the experiments. To validate the design of our robotic system, a phantom study and a preliminary human subject study were performed. Our results show that the robotic method can half the positional error and improve the rotational accuracy by up to two orders of magnitude. The accuracy is proven to be repeatable because the standard deviation of multiple trials is lowered by an order of magnitude. The improved actuation accuracy successfully translates to the TMS application, with a higher and more stable induced voltage in magnetic field sensors.

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A Preliminary Exploration Towards General Image Restoration

Despite the tremendous success of deep models in various individual image restoration tasks, there are at least two major technical challenges preventing these works from being applied to real-world usages: (1) the lack of generalization ability and (2) the complex and unknown degradations in real-world scenarios. Existing deep models, tailored for specific individual image restoration tasks, often fall short in effectively addressing these challenges. In this paper, we present a new problem called general image restoration (GIR) which aims to address these challenges within a unified model. GIR covers most individual image restoration tasks (\eg, image denoising, deblurring, deraining and super-resolution) and their combinations for general purposes. This paper proceeds to delineate the essential aspects of GIR, including problem definition and the overarching significance of generalization performance. Moreover, the establishment of new datasets and a thorough evaluation framework for GIR models is discussed. We conduct a comprehensive evaluation of existing approaches for tackling the GIR challenge, illuminating their strengths and pragmatic challenges. By analyzing these approaches, we not only underscore the effectiveness of GIR but also highlight the difficulties in its practical implementation. At last, we also try to understand and interpret these models' behaviors to inspire the future direction. Our work can open up new valuable research directions and contribute to the research of general vision.

cs.CV↗

Bi-Directional MS Lesion Filling and Synthesis Using Denoising Diffusion Implicit Model-based Lesion Repainting

Automatic magnetic resonance (MR) image processing pipelines are widely used to study people with multiple sclerosis (PwMS), encompassing tasks such as lesion segmentation and brain parcellation. However, the presence of lesion often complicates these analysis, particularly in brain parcellation. Lesion filling is commonly used to mitigate this issue, but existing lesion filling algorithms often fall short in accurately reconstructing realistic lesion-free images, which are vital for consistent downstream analysis. Additionally, the performance of lesion segmentation algorithms is often limited by insufficient data with lesion delineation as training labels. In this paper, we propose a novel approach leveraging Denoising Diffusion Implicit Models (DDIMs) for both MS lesion filling and synthesis based on image inpainting. Our modified DDIM architecture, once trained, enables both MS lesion filing and synthesis. Specifically, it can generate lesion-free T1-weighted or FLAIR images from those containing lesions; Or it can add lesions to T1-weighted or FLAIR images of healthy subjects. The former is essential for downstream analyses that require lesion-free images, while the latter is valuable for augmenting training datasets for lesion segmentation tasks. We validate our approach through initial experiments in this paper and demonstrate promising results in both lesion filling and synthesis, paving the way for future work.

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