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Ying Guo

Publications and source records attributed to Ying Guo.

At least 37 records · Page 2Linked to original sources

Dynamic Brain Transformer with Multi-level Attention for Functional Brain Network Analysis

Recent neuroimaging studies have highlighted the importance of network-centric brain analysis, particularly with functional magnetic resonance imaging. The emergence of Deep Neural Networks has fostered a substantial interest in predicting clinical outcomes and categorizing individuals based on brain networks. However, the conventional approach involving static brain network analysis offers limited potential in capturing the dynamism of brain function. Although recent studies have attempted to harness dynamic brain networks, their high dimensionality and complexity present substantial challenges. This paper proposes a novel methodology, Dynamic bRAin Transformer (DART), which combines static and dynamic brain networks for more effective and nuanced brain function analysis. Our model uses the static brain network as a baseline, integrating dynamic brain networks to enhance performance against traditional methods. We innovatively employ attention mechanisms, enhancing model explainability and exploiting the dynamic brain network's temporal variations. The proposed approach offers a robust solution to the low signal-to-noise ratio of blood-oxygen-level-dependent signals, a recurring issue in direct DNN modeling. It also provides valuable insights into which brain circuits or dynamic networks contribute more to final predictions. As such, DRAT shows a promising direction in neuroimaging studies, contributing to the comprehensive understanding of brain organization and the role of neural circuits.

q-bio.NC↗

Controllable Guide-Space for Generalizable Face Forgery Detection

Recent studies on face forgery detection have shown satisfactory performance for methods involved in training datasets, but are not ideal enough for unknown domains. This motivates many works to improve the generalization, but forgery-irrelevant information, such as image background and identity, still exists in different domain features and causes unexpected clustering, limiting the generalization. In this paper, we propose a controllable guide-space (GS) method to enhance the discrimination of different forgery domains, so as to increase the forgery relevance of features and thereby improve the generalization. The well-designed guide-space can simultaneously achieve both the proper separation of forgery domains and the large distance between real-forgery domains in an explicit and controllable manner. Moreover, for better discrimination, we use a decoupling module to weaken the interference of forgery-irrelevant correlations between domains. Furthermore, we make adjustments to the decision boundary manifold according to the clustering degree of the same domain features within the neighborhood. Extensive experiments in multiple in-domain and cross-domain settings confirm that our method can achieve state-of-the-art generalization.

cs.CV↗

Measuring photometric redshifts for high-redshift radio source surveys

With the advent of deep, all-sky radio surveys, the need for ancillary data to make the most of the new, high-quality radio data from surveys like the Evolutionary Map of the Universe (EMU), GLEAM-X, VLASS and LoTSS is growing rapidly. Radio surveys produce significant numbers of Active Galactic Nuclei (AGNs), and have a significantly higher average redshift when compared with optical and infrared all-sky surveys. Thus, traditional methods of estimating redshift are challenged, with spectroscopic surveys not reaching the redshift depth of radio surveys, and AGNs making it difficult for template fitting methods to accurately model the source. Machine Learning (ML) methods have been used, but efforts have typically been directed towards optically selected samples, or samples at significantly lower redshift than expected from upcoming radio surveys. This work compiles and homogenises a radio-selected dataset from both the northern hemisphere (making use of SDSS optical photometry), and southern hemisphere (making use of Dark Energy Survey optical photometry). We then test commonly used ML algorithms such as k-Nearest Neighbours (kNN), Random Forest, ANNz and GPz on this monolithic radio-selected sample. We show that kNN has the lowest percentage of catastrophic outliers, providing the best match for the majority of science cases in the EMU survey. We note that the wider redshift range of the combined dataset used allows for estimation of sources up to z = 3 before random scatter begins to dominate. When binning the data into redshift bins and treating the problem as a classification problem, we are able to correctly identify $\approx$76% of the highest redshift sources - sources at redshift z $>$ 2.51 - as being in either the highest bin (z $>$ 2.51), or second highest (z = 2.25).

astro-ph.IM↗

R-Mixup: Riemannian Mixup for Biological Networks

Biological networks are commonly used in biomedical and healthcare domains to effectively model the structure of complex biological systems with interactions linking biological entities. However, due to their characteristics of high dimensionality and low sample size, directly applying deep learning models on biological networks usually faces severe overfitting. In this work, we propose R-MIXUP, a Mixup-based data augmentation technique that suits the symmetric positive definite (SPD) property of adjacency matrices from biological networks with optimized training efficiency. The interpolation process in R-MIXUP leverages the log-Euclidean distance metrics from the Riemannian manifold, effectively addressing the swelling effect and arbitrarily incorrect label issues of vanilla Mixup. We demonstrate the effectiveness of R-MIXUP with five real-world biological network datasets on both regression and classification tasks. Besides, we derive a commonly ignored necessary condition for identifying the SPD matrices of biological networks and empirically study its influence on the model performance. The code implementation can be found in Appendix E.

cs.LG↗

Transformer-Based Hierarchical Clustering for Brain Network Analysis

Brain networks, graphical models such as those constructed from MRI, have been widely used in pathological prediction and analysis of brain functions. Within the complex brain system, differences in neuronal connection strengths parcellate the brain into various functional modules (network communities), which are critical for brain analysis. However, identifying such communities within the brain has been a nontrivial issue due to the complexity of neuronal interactions. In this work, we propose a novel interpretable transformer-based model for joint hierarchical cluster identification and brain network classification. Extensive experimental results on real-world brain network datasets show that with the help of hierarchical clustering, the model achieves increased accuracy and reduced runtime complexity while providing plausible insight into the functional organization of brain regions. The implementation is available at https://github.com/DDVD233/THC.

cs.LG↗

LOCUS: A Novel Decomposition Method for Brain Network Connectivity Matrices using Low-rank Structure with Uniform Sparsity

Network-oriented research has been increasingly popular in many scientific areas. In neuroscience research, imaging-based network connectivity measures have become the key for understanding brain organizations, potentially serving as individual neural fingerprints. There are major challenges in analyzing connectivity matrices including the high dimensionality of brain networks, unknown latent sources underlying the observed connectivity, and the large number of brain connections leading to spurious findings. In this paper, we propose a novel blind source separation method with low-rank structure and uniform sparsity (LOCUS) as a fully data-driven decomposition method for network measures. Compared with the existing method that vectorizes connectivity matrices ignoring brain network topology, LOCUS achieves more efficient and accurate source separation for connectivity matrices using low-rank structure. We propose a novel angle-based uniform sparsity regularization that demonstrates better performance than the existing sparsity controls for low-rank tensor methods. We propose a highly efficient iterative Node-Rotation algorithm that exploits the block multi-convexity of the objective function to solve the non-convex optimization problem for learning LOCUS. We illustrate the advantage of LOCUS through extensive simulation studies. Application of LOCUS to Philadelphia Neurodevelopmental Cohort neuroimaging study reveals biologically insightful connectivity traits which are not found using the existing method.

stat.ML↗

Simultaneously Optimizing Perturbations and Positions for Black-box Adversarial Patch Attacks

Adversarial patch is an important form of real-world adversarial attack that brings serious risks to the robustness of deep neural networks. Previous methods generate adversarial patches by either optimizing their perturbation values while fixing the pasting position or manipulating the position while fixing the patch's content. This reveals that the positions and perturbations are both important to the adversarial attack. For that, in this paper, we propose a novel method to simultaneously optimize the position and perturbation for an adversarial patch, and thus obtain a high attack success rate in the black-box setting. Technically, we regard the patch's position, the pre-designed hyper-parameters to determine the patch's perturbations as the variables, and utilize the reinforcement learning framework to simultaneously solve for the optimal solution based on the rewards obtained from the target model with a small number of queries. Extensive experiments are conducted on the Face Recognition (FR) task, and results on four representative FR models show that our method can significantly improve the attack success rate and query efficiency. Besides, experiments on the commercial FR service and physical environments confirm its practical application value. We also extend our method to the traffic sign recognition task to verify its generalization ability.

cs.CV↗

Adversarial Sticker: A Stealthy Attack Method in the Physical World

To assess the vulnerability of deep learning in the physical world, recent works introduce adversarial patches and apply them on different tasks. In this paper, we propose another kind of adversarial patch: the Meaningful Adversarial Sticker, a physically feasible and stealthy attack method by using real stickers existing in our life. Unlike the previous adversarial patches by designing perturbations, our method manipulates the sticker's pasting position and rotation angle on the objects to perform physical attacks. Because the position and rotation angle are less affected by the printing loss and color distortion, adversarial stickers can keep good attacking performance in the physical world. Besides, to make adversarial stickers more practical in real scenes, we conduct attacks in the black-box setting with the limited information rather than the white-box setting with all the details of threat models. To effectively solve for the sticker's parameters, we design the Region based Heuristic Differential Evolution Algorithm, which utilizes the new-found regional aggregation of effective solutions and the adaptive adjustment strategy of the evaluation criteria. Our method is comprehensively verified in the face recognition and then extended to the image retrieval and traffic sign recognition. Extensive experiments show the proposed method is effective and efficient in complex physical conditions and has a good generalization for different tasks.

cs.CV↗

BrainGB: A Benchmark for Brain Network Analysis with Graph Neural Networks

Mapping the connectome of the human brain using structural or functional connectivity has become one of the most pervasive paradigms for neuroimaging analysis. Recently, Graph Neural Networks (GNNs) motivated from geometric deep learning have attracted broad interest due to their established power for modeling complex networked data. Despite their superior performance in many fields, there has not yet been a systematic study of how to design effective GNNs for brain network analysis. To bridge this gap, we present BrainGB, a benchmark for brain network analysis with GNNs. BrainGB standardizes the process by (1) summarizing brain network construction pipelines for both functional and structural neuroimaging modalities and (2) modularizing the implementation of GNN designs. We conduct extensive experiments on datasets across cohorts and modalities and recommend a set of general recipes for effective GNN designs on brain networks. To support open and reproducible research on GNN-based brain network analysis, we host the BrainGB website at https://braingb.us with models, tutorials, examples, as well as an out-of-box Python package. We hope that this work will provide useful empirical evidence and offer insights for future research in this novel and promising direction.

q-bio.NC↗

Learning Task-Aware Effective Brain Connectivity for fMRI Analysis with Graph Neural Networks

Functional magnetic resonance imaging (fMRI) has become one of the most common imaging modalities for brain function analysis. Recently, graph neural networks (GNN) have been adopted for fMRI analysis with superior performance. Unfortunately, traditional functional brain networks are mainly constructed based on similarities among region of interests (ROI), which are noisy and agnostic to the downstream prediction tasks and can lead to inferior results for GNN-based models. To better adapt GNNs for fMRI analysis, we propose TBDS, an end-to-end framework based on \underline{T}ask-aware \underline{B}rain connectivity \underline{D}AG (short for Directed Acyclic Graph) \underline{S}tructure generation for fMRI analysis. The key component of TBDS is the brain network generator which adopts a DAG learning approach to transform the raw time-series into task-aware brain connectivities. Besides, we design an additional contrastive regularization to inject task-specific knowledge during the brain network generation process. Comprehensive experiments on two fMRI datasets, namely Adolescent Brain Cognitive Development (ABCD) and Philadelphia Neuroimaging Cohort (PNC) datasets demonstrate the efficacy of TBDS. In addition, the generated brain networks also highlight the prediction-related brain regions and thus provide unique interpretations of the prediction results. Our implementation will be published to https://github.com/yueyu1030/TBDS upon acceptance.

q-bio.NC↗

Brain Network Transformer

Human brains are commonly modeled as networks of Regions of Interest (ROIs) and their connections for the understanding of brain functions and mental disorders. Recently, Transformer-based models have been studied over different types of data, including graphs, shown to bring performance gains widely. In this work, we study Transformer-based models for brain network analysis. Driven by the unique properties of data, we model brain networks as graphs with nodes of fixed size and order, which allows us to (1) use connection profiles as node features to provide natural and low-cost positional information and (2) learn pair-wise connection strengths among ROIs with efficient attention weights across individuals that are predictive towards downstream analysis tasks. Moreover, we propose an Orthonormal Clustering Readout operation based on self-supervised soft clustering and orthonormal projection. This design accounts for the underlying functional modules that determine similar behaviors among groups of ROIs, leading to distinguishable cluster-aware node embeddings and informative graph embeddings. Finally, we re-standardize the evaluation pipeline on the only one publicly available large-scale brain network dataset of ABIDE, to enable meaningful comparison of different models. Experiment results show clear improvements of our proposed Brain Network Transformer on both the public ABIDE and our restricted ABCD datasets. The implementation is available at https://github.com/Wayfear/BrainNetworkTransformer.

cs.LG↗

Multi-Forgery Detection Challenge 2022: Push the Frontier of Unconstrained and Diverse Forgery Detection

In this paper, we present the Multi-Forgery Detection Challenge held concurrently with the IEEE Computer Society Workshop on Biometrics at CVPR 2022. Our Multi-Forgery Detection Challenge aims to detect automatic image manipulations including but not limited to image editing, image synthesis, image generation, image photoshop, etc. Our challenge has attracted 674 teams from all over the world, with about 2000 valid result submission counts. We invited the Top 10 teams to present their solutions to the challenge, from which three teams are awarded prizes in the grand finale. In this paper, we present the solutions from the Top 3 teams, in order to boost the research work in the field of image forgery detection.

cs.CV↗

Data-Efficient Brain Connectome Analysis via Multi-Task Meta-Learning

Brain networks characterize complex connectivities among brain regions as graph structures, which provide a powerful means to study brain connectomes. In recent years, graph neural networks have emerged as a prevalent paradigm of learning with structured data. However, most brain network datasets are limited in sample sizes due to the relatively high cost of data acquisition, which hinders the deep learning models from sufficient training. Inspired by meta-learning that learns new concepts fast with limited training examples, this paper studies data-efficient training strategies for analyzing brain connectomes in a cross-dataset setting. Specifically, we propose to meta-train the model on datasets of large sample sizes and transfer the knowledge to small datasets. In addition, we also explore two brain-network-oriented designs, including atlas transformation and adaptive task reweighing. Compared to other pre-training strategies, our meta-learning-based approach achieves higher and stabler performance, which demonstrates the effectiveness of our proposed solutions. The framework is also able to derive new insights regarding the similarities among datasets and diseases in a data-driven fashion.

cs.LG↗

FBNETGEN: Task-aware GNN-based fMRI Analysis via Functional Brain Network Generation

Functional magnetic resonance imaging (fMRI) is one of the most common imaging modalities to investigate brain functions. Recent studies in neuroscience stress the great potential of functional brain networks constructed from fMRI data for clinical predictions. Traditional functional brain networks, however, are noisy and unaware of downstream prediction tasks, while also incompatible with the deep graph neural network (GNN) models. In order to fully unleash the power of GNNs in network-based fMRI analysis, we develop FBNETGEN, a task-aware and interpretable fMRI analysis framework via deep brain network generation. In particular, we formulate (1) prominent region of interest (ROI) features extraction, (2) brain networks generation, and (3) clinical predictions with GNNs, in an end-to-end trainable model under the guidance of particular prediction tasks. Along with the process, the key novel component is the graph generator which learns to transform raw time-series features into task-oriented brain networks. Our learnable graphs also provide unique interpretations by highlighting prediction-related brain regions. Comprehensive experiments on two datasets, i.e., the recently released and currently largest publicly available fMRI dataset Adolescent Brain Cognitive Development (ABCD), and the widely-used fMRI dataset PNC, prove the superior effectiveness and interpretability of FBNETGEN. The implementation is available at https://github.com/Wayfear/FBNETGEN.

cs.LG↗

Identifying Critical LMS Features for Predicting At-risk Students

Learning management systems (LMSs) have become essential in higher education and play an important role in helping educational institutions to promote student success. Traditionally, LMSs have been used by postsecondary institutions in administration, reporting, and delivery of educational content. In this paper, we present an additional use of LMS by using its data logs to perform data-analytics and identify academically at-risk students. The data-driven insights would allow educational institutions and educators to develop and implement pedagogical interventions targeting academically at-risk students. We used anonymized data logs created by Brightspace LMS during fall 2019, spring 2020, and fall 2020 semesters at our college. Supervised machine learning algorithms were used to predict the final course performance of students, and several algorithms were found to perform well with accuracy above 90%. SHAP value method was used to assess the relative importance of features used in the predictive models. Unsupervised learning was also used to group students into different clusters based on the similarities in their interaction/involvement with LMS. In both of supervised and unsupervised learning, we identified two most-important features (Number_Of_Assignment_Submissions and Content_Completed). More importantly, our study lays a foundation and provides a framework for developing a real-time data analytics metric that may be incorporated into a LMS.

cs.CY↗

Improving Adversarial Transferability with Gradient Refining

Deep neural networks are vulnerable to adversarial examples, which are crafted by adding human-imperceptible perturbations to original images. Most existing adversarial attack methods achieve nearly 100% attack success rates under the white-box setting, but only achieve relatively low attack success rates under the black-box setting. To improve the transferability of adversarial examples for the black-box setting, several methods have been proposed, e.g., input diversity, translation-invariant attack, and momentum-based attack. In this paper, we propose a method named Gradient Refining, which can further improve the adversarial transferability by correcting useless gradients introduced by input diversity through multiple transformations. Our method is generally applicable to many gradient-based attack methods combined with input diversity. Extensive experiments are conducted on the ImageNet dataset and our method can achieve an average transfer success rate of 82.07% for three different models under single-model setting, which outperforms the other state-of-the-art methods by a large margin of 6.0% averagely. And we have applied the proposed method to the competition CVPR 2021 Unrestricted Adversarial Attacks on ImageNet organized by Alibaba and won the second place in attack success rates among 1558 teams.

cs.CV↗

Unrestricted Adversarial Attacks on ImageNet Competition

Many works have investigated the adversarial attacks or defenses under the settings where a bounded and imperceptible perturbation can be added to the input. However in the real-world, the attacker does not need to comply with this restriction. In fact, more threats to the deep model come from unrestricted adversarial examples, that is, the attacker makes large and visible modifications on the image, which causes the model classifying mistakenly, but does not affect the normal observation in human perspective. Unrestricted adversarial attack is a popular and practical direction but has not been studied thoroughly. We organize this competition with the purpose of exploring more effective unrestricted adversarial attack algorithm, so as to accelerate the academical research on the model robustness under stronger unbounded attacks. The competition is held on the TianChi platform (\url{https://tianchi.aliyun.com/competition/entrance/531853/introduction}) as one of the series of AI Security Challengers Program.

cs.CV↗

Simultaneous Cluster Structure Learning and Estimation of Heterogeneous Graphs for Matrix-variate fMRI Data

Graphical models play an important role in neuroscience studies, particularly in brain connectivity analysis. Typically, observations/samples are from several heterogenous groups and the group membership of each observation/sample is unavailable, which poses a great challenge for graph structure learning. In this article, we propose a method which can achieve Simultaneous Clustering and Estimation of Heterogeneous Graphs (briefly denoted as SCEHG) for matrix-variate function Magnetic Resonance Imaging (fMRI) data. Unlike the conventional clustering methods which rely on the mean differences of various groups, the proposed SCEHG method fully exploits the group differences of conditional dependence relationships among brain regions for learning cluster structure. In essence, by constructing individual-level between-region network measures, we formulate clustering as penalized regression with grouping and sparsity pursuit, which transforms the unsupervised learning into supervised learning. An ADMM algorithm is proposed to solve the corresponding optimization problem. We also propose a generalized criterion to specify the number of clusters. Extensive simulation studies illustrate the superiority of the SCEHG method over some state-of-the-art methods in terms of both clustering and graph recovery accuracy. We also apply the SCEHG procedure to analyze fMRI data associated with ADHD (abbreviated for Attention Deficit Hyperactivity Disorder), which illustrate its empirical usefulness. An R package ``SCEHG" to implement the method is available at https://github.com/heyongstat/SCEHG.

stat.ME↗