arXiv subjects

Yingfeng Wang

Publications and source records attributed to Yingfeng Wang.

10 recordsLinked to original sources

arXiv2026

Quantum Sparse Autoencoders for Q-Matrix Estimation in Cognitive Diagnosis

Q-matrices play a central role in cognitive diagnosis within educational data mining (EDM), specifying which latent skills each assessment item requires. Data-driven Q-matrix estimation remains challenging when assessments involve many correlated skills and when real response patterns depart from idealized generative assumptions. We introduce a novel quantum sparse autoencoder (QSAE) for Q-matrix estimation, which, to the best of our knowledge, is the first application of quantum machine learning (QML) to cognitive diagnosis. Overall, the QSAE embeds each student's binary response vector into a quantum circuit using an encoder, compresses it into a sparse latent representation, and maps that representation to the Q-matrix. We benchmark the QSAE against a classical autoencoder (CAE) across 60 simulated datasets and 9 real-world assessment datasets. The results reveal complementary strengths. Although the CAE partially achieves higher average accuracy under several simulation conditions, the QSAE is substantially more stable across replications, exhibiting lower variance in 49 of the 60 conditions. Moreover, on real assessment data, the QSAE outperforms the CAE on 6 of the 9 datasets. These findings suggest that the principal advancement of QML in this setting is not universal accuracy improvement, but enhanced robustness and capability to explore latent-structure complexity in real datasets.

cs.LG↗

arXiv2026

Absent, Not Faint: Fisher-Information Limits and a Logarithmic Measurement-Design Cure for Passive Characterization of Coherent Qubit Noise

Calibrating a quantum processor means estimating error parameters, and estimation theory usually assumes a parameter hard to estimate is faint: its signal is weak but present, so more repetitions or a richer model will recover it. This assumption fails for a leading hardware fault. A coherent over-rotation is a small systematic gate miscalibration. Measured through the cheapest data a device returns--one fixed-basis histogram--it is not faint but absent: to first order it leaves the distribution unchanged, indistinguishable from a compensating stochastic error, exactly as two numbers cannot be separated from their sum. For commuting single- and two-qubit transverse over-rotations, with known support on the canonical input, the histogram's Fisher information is singular along the fault's direction at zero angle, its Cramer-Rao bound is infinite, and no finite-variance, locally unbiased estimator recovers it. At a generic nonzero angle the degeneracy partly lifts; beyond four qubits it clears entirely, leaving conditioning, not absence, as the obstruction. The cure is a richer measurement, not a richer model: a fixed, logarithmically small set of extra settings makes every such fault visible. Visibility alone is not enough. The sampling cost is set by conditioning, not coverage, through a floor whose complete-family closed form is exponentially small in the qubit count. We prove the impossibility and cure, confirm both in exact simulation, show conditioning predicts recovery error across hundreds of designs, and observe a 3-5x bias gap on IBM Heron hardware as a consistency check. Non-commuting faults and unknown support remain open.

quant-ph↗

arXiv2026

Head Similarity: Modeling Structured Whole-Head Appearance Beyond Face Recognition

Many vision applications require identity consistency beyond strict biometric recognition, especially under non-frontal views or when facial cues are missing. However, conventional face recognition models enforce intra-identity invariance, collapsing appearance variations such as hairstyle or styling changes into a single representation, limiting their use in appearance-sensitive scenarios. To address this limitation, we introduce Head Similarity, a new formulation that extends identity-centric recognition to structured whole-head similarity modeling. Our approach explicitly captures intra-identity appearance variation and enforces hierarchical similarity ordering across identity and appearance states, enabling meaningful comparison even under occlusion or rear-view conditions. We construct a large-scale benchmark from long-form videos with weakly-supervised appearance states, covering diverse poses, occlusions, and temporal changes. As a first step, we develop a simple yet effective framework that jointly models identity discrimination and appearance-sensitive similarity through hierarchical supervision and identity-aware distillation. Experiments show that conventional face recognition models fail to capture appearance-dependent similarity, while our approach demonstrates the feasibility of structured whole-head similarity modeling.

cs.CV↗

arXiv2026

MS2MetGAN: Latent-space adversarial training for metabolite-spectrum matching in MS/MS database search

Database search is a widely used approach for identifying metabolites from tandem mass spectra (MS/MS). In this strategy, an experimental spectrum is matched against a user-specified database of candidate metabolites, and candidates are ranked such that true metabolite-spectrum matches receive the highest scores. Machine-learning methods have been widely incorporated into database-search-based identification tools and have substantially improved performance. To further improve identification accuracy, we propose a new framework for generating negative training samples. The framework first uses autoencoders to learn latent representations of metabolite structures and MS/MS spectra, thereby recasting metabolite-spectrum matching as matching between latent vectors. It then uses a GAN to generate latent vectors of decoy metabolites and constructs decoy metabolite-spectrum matches as negative samples for training. Experimental results show that our tool, MS2MetGAN, achieves better overall performance than existing metabolite identification methods.

cs.LG↗

arXiv2025

CLAQS: Compact Learnable All-Quantum Token Mixer with Shared-ansatz for Text Classification

Quantum compute is scaling fast, from cloud QPUs to high throughput GPU simulators, making it timely to prototype quantum NLP beyond toy tasks. However, devices remain qubit limited and depth limited, training can be unstable, and classical attention is compute and memory heavy. This motivates compact, phase aware quantum token mixers that stabilize amplitudes and scale to long sequences. We present CLAQS, a compact, fully quantum token mixer for text classification that jointly learns complex-valued mixing and nonlinear transformations within a unified quantum circuit. To enable stable end-to-end optimization, we apply l1 normalization to regulate amplitude scaling and introduce a two-stage parameterized quantum architecture that decouples shared token embeddings from a window-level quantum feed-forward module. Operating under a sliding-window regime with document-level aggregation, CLAQS requires only eight data qubits and shallow circuits, yet achieves 91.64% accuracy on SST-2 and 87.08% on IMDB, outperforming both classical Transformer baselines and strong hybrid quantum-classical counterparts.

quant-ph↗

arXiv2025

Quantum-Classical Hybrid Molecular Autoencoder for Advancing Classical Decoding

Although recent advances in quantum machine learning (QML) offer significant potential for enhancing generative models, particularly in molecular design, a large array of classical approaches still face challenges in achieving high fidelity and validity. In particular, the integration of QML with sequence-based tasks, such as Simplified Molecular Input Line Entry System (SMILES) string reconstruction, remains underexplored and usually suffers from fidelity degradation. In this work, we propose a hybrid quantum-classical architecture for SMILES reconstruction that integrates quantum encoding with classical sequence modeling to improve quantum fidelity and classical similarity. Our approach achieves a quantum fidelity of approximately 84% and a classical reconstruction similarity of 60%, surpassing existing quantum baselines. Our work lays a promising foundation for future QML applications, striking a balance between expressive quantum representations and classical sequence models and catalyzing broader research on quantum-aware sequence models for molecular and drug discovery.

cs.LG↗

arXiv2025

Bridging Classical and Quantum Computing for Next-Generation Language Models

Integrating Large Language Models (LLMs) with quantum computing is a critical challenge, hindered by the severe constraints of Noisy Intermediate-Scale Quantum (NISQ) devices, including barren plateaus and limited coherence. Current approaches often fail due to static quantum-classical partitioning. We introduce Adaptive Quantum-Classical Fusion (AQCF), the first framework to bridge this gap through dynamic, quantum-classical co-design. AQCF's core principle is real-time adaptation: it analyzes input complexity to orchestrate seamless transitions between classical and quantum processing. The framework features three key innovations: (1) entropy-driven adaptive circuits that circumvent barren plateaus; (2) quantum memory banks that unify classical attention with quantum state-based similarity retrieval; and (3) intelligent fusion controllers that allocate tasks for optimal performance. This architecture maintains full compatibility with classical Transformers while progressively incorporating quantum advantages. Experiments on sentiment analysis demonstrate that AQCF achieves competitive performance, significantly improves quantum resource efficiency, and operates successfully within typical NISQ constraints. By providing a seamless integration pathway, AQCF offers both immediate practical value on current quantum hardware and a clear evolution path toward mature Quantum LLMs.

quant-ph↗

arXiv2025

MolQAE: Quantum Autoencoder for Molecular Representation Learning

We introduce Quantum Molecular Autoencoder (MolQAE), the first quantum autoencoder to leverage the complete molecular structures. MolQAE uniquely maps SMILES strings directly to quantum states using parameterized rotation gates, preserving vital structural information. Its quantum encoder-decoder framework enables latent space compression and reconstruction. A dual-objective strategy optimizes fidelity and minimizes trash state deviation. Our evaluations demonstrate effective capture of molecular characteristics and a remarkable preservation of fidelity, approaching robust molecular reconstruction even with substantial dimensionality reduction. Our model establishes a quantum pathway in cheminformatics by being the first to process complete molecular structural information with a dedicated quantum architecture considering the Noisy Intermediate-Scale Quantum (NISQ)-era development and promising significant advances in drug and materials discovery.

quant-ph↗

arXiv2025

Large Language Models for Bioinformatics

With the rapid advancements in large language model (LLM) technology and the emergence of bioinformatics-specific language models (BioLMs), there is a growing need for a comprehensive analysis of the current landscape, computational characteristics, and diverse applications. This survey aims to address this need by providing a thorough review of BioLMs, focusing on their evolution, classification, and distinguishing features, alongside a detailed examination of training methodologies, datasets, and evaluation frameworks. We explore the wide-ranging applications of BioLMs in critical areas such as disease diagnosis, drug discovery, and vaccine development, highlighting their impact and transformative potential in bioinformatics. We identify key challenges and limitations inherent in BioLMs, including data privacy and security concerns, interpretability issues, biases in training data and model outputs, and domain adaptation complexities. Finally, we highlight emerging trends and future directions, offering valuable insights to guide researchers and clinicians toward advancing BioLMs for increasingly sophisticated biological and clinical applications.

q-bio.QM↗

arXiv2022

Cointegration of SARS-CoV-2 Transmission with Weather Conditions and Mobility during the First Year of the COVID-19 Pandemic in the United States

Correlation between weather and the transmission of SARS-CoV-2 may suggest its seasonality. Cointegration analysis can avoid spurious correlation among time series data. We examined the cointegration of virus transmission with daily temperature, dewpoint, and confounding factors of mobility measurements during the first year of the pandemic in the United States. We examined the cointegration of the effective reproductive rate, Rt, of the virus with the dewpoint at two meters, the temperature at two meters, Apple driving mobility, and Google workplace mobility measurements. We found that dewpoint and Apple driving mobility are the best factors to cointegrate with Rt, although temperature and Google workplace mobility also cointegrate with Rt at substantial levels. We found that the optimal lag is two days for cointegration between Rt and weather variables, and three days for Rt and mobility. We observed clusters of states that share similar cointegration results of Rt, weather, and mobility, suggesting regional patterns. Our results support the correlation of weather with the spread of SARS-CoV-2 and its potential seasonality.

q-bio.PE↗