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Yingxian Xia

Publications and source records attributed to Yingxian Xia.

3 recordsLinked to original sources

Foveated-Imaging Geometry CT Architecture and Seeded Diffusion Model Enabling Global Super-Resolution Reconstruction

For X-ray computed tomography (CT), a smaller detector pixel size generally leads to higher scanner spatial resolution, but inevitably increases system cost as well as data overhead in acquisition and processing. To achieve high-resolution (HR) CT imaging in a more resource-efficient manner, we propose a Foveated-Imaging Geometry CT (FIGCT) architecture, which integrates local HR data into an acquisition scheme dominated by low-resolution (LR) measurements. We further develop a Diffusion Probabilistic FIGCT Super-Resolution Reconstruction (DPFSR) framework to generate global HR CT images over the full field of view (FOV). The concept of FIGCT is first established, and its typical configurations are characterized according to the arrangement of HR data. Two key indices, namely the HR data fraction (HDF) and the LR-to-HR detector pixel size ratio (LHR), are introduced to describe the FIGCT geometry. The proposed DPFSR incorporates local HR information into intermediate clean-image estimates in both the projection and image domains during the reverse diffusion process. This additional step not only guides HR image generation from LR data, but also improves data consistency between the clean-image estimates and the originally measured data. Preliminary numerical simulation results on FIGCT show that the proposed architecture provides high-precision CT images within the region of interest (ROI) corresponding to the HR data, while the spatial resolution deteriorates rapidly outside the ROI. With DPFSR, global HR reconstruction is achieved on the AAPM Grand Challenge dataset and swine lung CT data, outperforming existing SR methods in terms of Learned Perceptual Image Patch Similarity (LPIPS), PSNR, and SSIM.

physics.med-ph

ComptoNet: An End-to-End Deep Learning Framework for Scatter Estimation in Multi-Source Stationary CT

Multi-source stationary computed tomography (MSS-CT) offers significant advantages in medical and industrial applications due to its gantry-less scan architecture and/or capability of simultaneous multi-source emission. However, the lack of anti-scatter grid deployment in MSS-CT results in severe forward and/or cross scatter contamination, presenting a critical challenge that necessitates an accurate and efficient scatter correction. In this work, ComptoNet, an innovative end-to-end deep learning framework for scatter estimation in MSS-CT, is proposed, which integrates Compton-scattering physics with deep learning techniques to address the challenges of scatter estimation effectively. Central to ComptoNet is the Compton-map, a novel concept that captures the distribution of scatter signals outside the scan field of view, primarily consisting of large-angle Compton scatter. In ComptoNet, a reference Compton-map and/or spare detector data are used to guide the physics-driven deep estimation of scatter from simultaneous emissions by multiple sources. Additionally, a frequency attention module is employed for enhancing the low-frequency smoothness. Such a multi-source deep scatter estimation framework decouples the cross and forward scatter. It reduces network complexity and ensures a consistent low-frequency signature with different photon numbers of simulations, as evidenced by mean absolute percentage errors (MAPEs) that are less than $1.26\%$. Conducted by using data generated from Monte Carlo simulations with various phantoms, experiments demonstrate the effectiveness of ComptoNet, with significant improvements in scatter estimation accuracy (a MAPE of $0.84\%$). After scatter correction, nearly artifact-free CT images are obtained, further validating the capability of our proposed ComptoNet in mitigating scatter-induced errors.

physics.med-ph

Generalized-Equiangular Geometry CT: Concept and Shift-Invariant FBP Algorithms

With advanced X-ray source and detector technologies being continuously developed, non-traditional CT geometries have been widely explored. Generalized-Equiangular Geometry CT (GEGCT) architecture, in which an X-ray source might be positioned radially far away from the focus of arced detector array that is equiangularly spaced, is of importance in many novel CT systems and designs. GEGCT, unfortunately, has no theoretically exact and shift-invariant analytical image reconstruction algorithm in general. In this study, to obtain fast and accurate reconstruction from GEGCT and to promote its system design and optimization, an in-depth investigation on a group of approximate Filtered BackProjection (FBP) algorithms with a variety of weighting strategies has been conducted. The architecture of GEGCT is first presented and characterized by using a normalized-radial-offset distance (NROD). Next, shift-invariant weighted FBP-type algorithms are derived in a unified framework, with pre-filtering, filtering, and post-filtering weights. Three viable weighting strategies are then presented including a classic one developed by Besson in the literature and two new ones generated from a curvature fitting and from an empirical formula, where all of the three weights can be expressed as certain functions of NROD. After that, an analysis of reconstruction accuracy is conducted with a wide range of NROD. We further stretch the weighted FBP-type algorithms to GEGCT with dynamic NROD. Finally, the weighted FBP algorithm for GEGCT is extended to a three-dimensional form in the case of cone-beam scan with a cylindrical detector array.

physics.med-ph