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Yingying Zhu

Publications and source records attributed to Yingying Zhu.

54 records · Page 3Linked to original sources

Memory Efficient Temporal & Visual Graph Model for Unsupervised Video Domain Adaptation

Existing video domain adaption (DA) methods need to store all temporal combinations of video frames or pair the source and target videos, which are memory cost expensive and can't scale up to long videos. To address these limitations, we propose a memory-efficient graph-based video DA approach as follows. At first our method models each source or target video by a graph: nodes represent video frames and edges represent the temporal or visual similarity relationship between frames. We use a graph attention network to learn the weight of individual frames and simultaneously align the source and target video into a domain-invariant graph feature space. Instead of storing a large number of sub-videos, our method only constructs one graph with a graph attention mechanism for one video, reducing the memory cost substantially. The extensive experiments show that, compared with the state-of-art methods, we achieved superior performance while reducing the memory cost significantly.

cs.CV↗

Exploring Resolution and Degradation Clues as Self-supervised Signal for Low Quality Object Detection

Image restoration algorithms such as super resolution (SR) are indispensable pre-processing modules for object detection in low quality images. Most of these algorithms assume the degradation is fixed and known a priori. However, in practical, either the real degradation or optimal up-sampling ratio rate is unknown or differs from assumption, leading to a deteriorating performance for both the pre-processing module and the consequent high-level task such as object detection. Here, we propose a novel self-supervised framework to detect objects in degraded low resolution images. We utilizes the downsampling degradation as a kind of transformation for self-supervised signals to explore the equivariant representation against various resolutions and other degradation conditions. The Auto Encoding Resolution in Self-supervision (AERIS) framework could further take the advantage of advanced SR architectures with an arbitrary resolution restoring decoder to reconstruct the original correspondence from the degraded input image. Both the representation learning and object detection are optimized jointly in an end-to-end training fashion. The generic AERIS framework could be implemented on various mainstream object detection architectures with different backbones. The extensive experiments show that our methods has achieved superior performance compared with existing methods when facing variant degradation situations. Code would be released at https://github.com/cuiziteng/ECCV_AERIS.

cs.CV↗

A Privacy-Preserving Unsupervised Domain Adaptation Framework for Clinical Text Analysis

Unsupervised domain adaptation (UDA) generally aligns the unlabeled target domain data to the distribution of the source domain to mitigate the distribution shift problem. The standard UDA requires sharing the source data with the target, having potential data privacy leaking risks. To protect the source data's privacy, we first propose to share the source feature distribution instead of the source data. However, sharing only the source feature distribution may still suffer from the membership inference attack who can infer an individual's membership by the black-box access to the source model. To resolve this privacy issue, we further study the under-explored problem of privacy-preserving domain adaptation and propose a method with a novel differential privacy training strategy to protect the source data privacy. We model the source feature distribution by Gaussian Mixture Models (GMMs) under the differential privacy setting and send it to the target client for adaptation. The target client resamples differentially private source features from GMMs and adapts on target data with several state-of-art UDA backbones. With our proposed method, the source data provider could avoid leaking source data privacy during domain adaptation as well as reserve the utility. To evaluate our proposed method's utility and privacy loss, we apply our model on a medical report disease label classification task using two noisy challenging clinical text datasets. The results show that our proposed method can preserve source data's privacy with a minor performance influence on the text classification task.

cs.CL↗

RestoreDet: Degradation Equivariant Representation for Object Detection in Low Resolution Images

Image restoration algorithms such as super resolution (SR) are indispensable pre-processing modules for object detection in degraded images. However, most of these algorithms assume the degradation is fixed and known a priori. When the real degradation is unknown or differs from assumption, both the pre-processing module and the consequent high-level task such as object detection would fail. Here, we propose a novel framework, RestoreDet, to detect objects in degraded low resolution images. RestoreDet utilizes the downsampling degradation as a kind of transformation for self-supervised signals to explore the equivariant representation against various resolutions and other degradation conditions. Specifically, we learn this intrinsic visual structure by encoding and decoding the degradation transformation from a pair of original and randomly degraded images. The framework could further take the advantage of advanced SR architectures with an arbitrary resolution restoring decoder to reconstruct the original correspondence from the degraded input image. Both the representation learning and object detection are optimized jointly in an end-to-end training fashion. RestoreDet is a generic framework that could be implemented on any mainstream object detection architectures. The extensive experiment shows that our framework based on CenterNet has achieved superior performance compared with existing methods when facing variant degradation situations. Our code would be released soon.

eess.IV↗

Leveraging Human Selective Attention for Medical Image Analysis with Limited Training Data

The human gaze is a cost-efficient physiological data that reveals human underlying attentional patterns. The selective attention mechanism helps the cognition system focus on task-relevant visual clues by ignoring the presence of distractors. Thanks to this ability, human beings can efficiently learn from a very limited number of training samples. Inspired by this mechanism, we aim to leverage gaze for medical image analysis tasks with small training data. Our proposed framework includes a backbone encoder and a Selective Attention Network (SAN) that simulates the underlying attention. The SAN implicitly encodes information such as suspicious regions that is relevant to the medical diagnose tasks by estimating the actual human gaze. Then we design a novel Auxiliary Attention Block (AAB) to allow information from SAN to be utilized by the backbone encoder to focus on selective areas. Specifically, this block uses a modified version of a multi-head attention layer to simulate the human visual search procedure. Note that the SAN and AAB can be plugged into different backbones, and the framework can be used for multiple medical image analysis tasks when equipped with task-specific heads. Our method is demonstrated to achieve superior performance on both 3D tumor segmentation and 2D chest X-ray classification tasks. We also show that the estimated gaze probability map of the SAN is consistent with an actual gaze fixation map obtained by board-certified doctors.

cs.CV↗

Automated Generation of Accurate \& Fluent Medical X-ray Reports

Our paper focuses on automating the generation of medical reports from chest X-ray image inputs, a critical yet time-consuming task for radiologists. Unlike existing medical re-port generation efforts that tend to produce human-readable reports, we aim to generate medical reports that are both fluent and clinically accurate. This is achieved by our fully differentiable and end-to-end paradigm containing three complementary modules: taking the chest X-ray images and clinical his-tory document of patients as inputs, our classification module produces an internal check-list of disease-related topics, referred to as enriched disease embedding; the embedding representation is then passed to our transformer-based generator, giving rise to the medical reports; meanwhile, our generator also pro-duces the weighted embedding representation, which is fed to our interpreter to ensure consistency with respect to disease-related topics.Our approach achieved promising results on commonly-used metrics concerning language fluency and clinical accuracy. Moreover, noticeable performance gains are consistently ob-served when additional input information is available, such as the clinical document and extra scans of different views.

cs.CL↗

Cross-view Geo-localization with Evolving Transformer

In this work, we address the problem of cross-view geo-localization, which estimates the geospatial location of a street view image by matching it with a database of geo-tagged aerial images. The cross-view matching task is extremely challenging due to drastic appearance and geometry differences across views. Unlike existing methods that predominantly fall back on CNN, here we devise a novel evolving geo-localization Transformer (EgoTR) that utilizes the properties of self-attention in Transformer to model global dependencies, thus significantly decreasing visual ambiguities in cross-view geo-localization. We also exploit the positional encoding of Transformer to help the EgoTR understand and correspond geometric configurations between ground and aerial images. Compared to state-of-the-art methods that impose strong assumption on geometry knowledge, the EgoTR flexibly learns the positional embeddings through the training objective and hence becomes more practical in many real-world scenarios. Although Transformer is well suited to our task, its vanilla self-attention mechanism independently interacts within image patches in each layer, which overlooks correlations between layers. Instead, this paper propose a simple yet effective self-cross attention mechanism to improve the quality of learned representations. The self-cross attention models global dependencies between adjacent layers, which relates between image patches while modeling how features evolve in the previous layer. As a result, the proposed self-cross attention leads to more stable training, improves the generalization ability and encourages representations to keep evolving as the network goes deeper. Extensive experiments demonstrate that our EgoTR performs favorably against state-of-the-art methods on standard, fine-grained and cross-dataset cross-view geo-localization tasks.

cs.CV↗

RustViz: Interactively Visualizing Ownership and Borrowing

Rust is a systems programming language that guarantees memory safety without the need for a garbage collector by statically tracking ownership and borrowing events. The associated rules are subtle and unique among industry programming languages, which can make learning Rust more challenging. Motivated by the challenges that Rust learners face, we are developing RustViz, a tool that allows teachers to generate an interactive timeline depicting ownership and borrowing events for each variable in a Rust code example. These visualizations are intended to help Rust learners develop an understanding of ownership and borrowing by example. This paper introduces RustViz by example, shows how teachers can use it to generate visualizations, describes learning goals, and proposes a study designed to evaluate RustViz based on these learning goals.

cs.PL↗

Multi-modal, multi-task, multi-attention (M3) deep learning detection of reticular pseudodrusen: towards automated and accessible classification of age-related macular degeneration

Objective Reticular pseudodrusen (RPD), a key feature of age-related macular degeneration (AMD), are poorly detected by human experts on standard color fundus photography (CFP) and typically require advanced imaging modalities such as fundus autofluorescence (FAF). The objective was to develop and evaluate the performance of a novel 'M3' deep learning framework on RPD detection. Materials and Methods A deep learning framework M3 was developed to detect RPD presence accurately using CFP alone, FAF alone, or both, employing >8000 CFP-FAF image pairs obtained prospectively (Age-Related Eye Disease Study 2). The M3 framework includes multi-modal (detection from single or multiple image modalities), multi-task (training different tasks simultaneously to improve generalizability), and multi-attention (improving ensembled feature representation) operation. Performance on RPD detection was compared with state-of-the-art deep learning models and 13 ophthalmologists; performance on detection of two other AMD features (geographic atrophy and pigmentary abnormalities) was also evaluated. Results For RPD detection, M3 achieved area under receiver operating characteristic (AUROC) 0.832, 0.931, and 0.933 for CFP alone, FAF alone, and both, respectively. M3 performance on CFP was very substantially superior to human retinal specialists (median F1-score 0.644 versus 0.350). External validation (on Rotterdam Study, Netherlands) demonstrated high accuracy on CFP alone (AUROC 0.965). The M3 framework also accurately detected geographic atrophy and pigmentary abnormalities (AUROC 0.909 and 0.912, respectively), demonstrating its generalizability. Conclusion This study demonstrates the successful development, robust evaluation, and external validation of a novel deep learning framework that enables accessible, accurate, and automated AMD diagnosis and prognosis.

cs.CV↗

COVID-19-CT-CXR: a freely accessible and weakly labeled chest X-ray and CT image collection on COVID-19 from biomedical literature

The latest threat to global health is the COVID-19 outbreak. Although there exist large datasets of chest X-rays (CXR) and computed tomography (CT) scans, few COVID-19 image collections are currently available due to patient privacy. At the same time, there is a rapid growth of COVID-19-relevant articles in the biomedical literature. Here, we present COVID-19-CT-CXR, a public database of COVID-19 CXR and CT images, which are automatically extracted from COVID-19-relevant articles from the PubMed Central Open Access (PMC-OA) Subset. We extracted figures, associated captions, and relevant figure descriptions in the article and separated compound figures into subfigures. We also designed a deep-learning model to distinguish them from other figure types and to classify them accordingly. The final database includes 1,327 CT and 263 CXR images (as of May 9, 2020) with their relevant text. To demonstrate the utility of COVID-19-CT-CXR, we conducted four case studies. (1) We show that COVID-19-CT-CXR, when used as additional training data, is able to contribute to improved DL performance for the classification of COVID-19 and non-COVID-19 CT. (2) We collected CT images of influenza and trained a DL baseline to distinguish a diagnosis of COVID-19, influenza, or normal or other types of diseases on CT. (3) We trained an unsupervised one-class classifier from non-COVID-19 CXR and performed anomaly detection to detect COVID-19 CXR. (4) From text-mined captions and figure descriptions, we compared clinical symptoms and clinical findings of COVID-19 vs. those of influenza to demonstrate the disease differences in the scientific publications. We believe that our work is complementary to existing resources and hope that it will contribute to medical image analysis of the COVID-19 pandemic. The dataset, code, and DL models are publicly available at https://github.com/ncbi-nlp/COVID-19-CT-CXR.

eess.IV↗

E$^2$Net: An Edge Enhanced Network for Accurate Liver and Tumor Segmentation on CT Scans

Developing an effective liver and liver tumor segmentation model from CT scans is very important for the success of liver cancer diagnosis, surgical planning and cancer treatment. In this work, we propose a two-stage framework for 2D liver and tumor segmentation. The first stage is a coarse liver segmentation network, while the second stage is an edge enhanced network (E$^2$Net) for more accurate liver and tumor segmentation. E$^2$Net explicitly models complementary objects (liver and tumor) and their edge information within the network to preserve the organ and lesion boundaries. We introduce an edge prediction module in E$^2$Net and design an edge distance map between liver and tumor boundaries, which is used as an extra supervision signal to train the edge enhanced network. We also propose a deep cross feature fusion module to refine multi-scale features from both objects and their edges. E$^2$Net is more easily and efficiently trained with a small labeled dataset, and it can be trained/tested on the original 2D CT slices (resolve resampling error issue in 3D models). The proposed framework has shown superior performance on both liver and liver tumor segmentation compared to several state-of-the-art 2D, 3D and 2D/3D hybrid frameworks.

eess.IV↗

Cross-Domain Medical Image Translation by Shared Latent Gaussian Mixture Model

Current deep learning based segmentation models often generalize poorly between domains due to insufficient training data. In real-world clinical applications, cross-domain image analysis tools are in high demand since medical images from different domains are often needed to achieve a precise diagnosis. An important example in radiology is generalizing from non-contrast CT to contrast enhanced CTs. Contrast enhanced CT scans at different phases are used to enhance certain pathologies or organs. Many existing cross-domain image-to-image translation models have been shown to improve cross-domain segmentation of large organs. However, such models lack the ability to preserve fine structures during the translation process, which is significant for many clinical applications, such as segmenting small calcified plaques in the aorta and pelvic arteries. In order to preserve fine structures during medical image translation, we propose a patch-based model using shared latent variables from a Gaussian mixture model. We compare our image translation framework to several state-of-the-art methods on cross-domain image translation and show our model does a better job preserving fine structures. The superior performance of our model is verified by performing two tasks with the translated images - detection and segmentation of aortic plaques and pancreas segmentation. We expect the utility of our framework will extend to other problems beyond segmentation due to the improved quality of the generated images and enhanced ability to preserve small structures.

eess.IV↗

Image Translation by Latent Union of Subspaces for Cross-Domain Plaque Detection

Calcified plaque in the aorta and pelvic arteries is associated with coronary artery calcification and is a strong predictor of heart attack. Current calcified plaque detection models show poor generalizability to different domains (ie. pre-contrast vs. post-contrast CT scans). Many recent works have shown how cross domain object detection can be improved using an image translation model which translates between domains using a single shared latent space. However, while current image translation models do a good job preserving global/intermediate level structures they often have trouble preserving tiny structures. In medical imaging applications, preserving small structures is important since these structures can carry information which is highly relevant for disease diagnosis. Recent works on image reconstruction show that complex real-world images are better reconstructed using a union of subspaces approach. Since small image patches are used to train the image translation model, it makes sense to enforce that each patch be represented by a linear combination of subspaces which may correspond to the different parts of the body present in that patch. Motivated by this, we propose an image translation network using a shared union of subspaces constraint and show our approach preserves subtle structures (plaques) better than the conventional method. We further applied our method to a cross domain plaque detection task and show significant improvement compared to the state-of-the art method.

cs.CV↗

GeoCapsNet: Aerial to Ground view Image Geo-localization using Capsule Network

The task of cross-view image geo-localization aims to determine the geo-location (GPS coordinates) of a query ground-view image by matching it with the GPS-tagged aerial (satellite) images in a reference dataset. Due to the dramatic changes of viewpoint, matching the cross-view images is challenging. In this paper, we propose the GeoCapsNet based on the capsule network for ground-to-aerial image geo-localization. The network first extracts features from both ground-view and aerial images via standard convolution layers and the capsule layers further encode the features to model the spatial feature hierarchies and enhance the representation power. Moreover, we introduce a simple and effective weighted soft-margin triplet loss with online batch hard sample mining, which can greatly improve image retrieval accuracy. Experimental results show that our GeoCapsNet significantly outperforms the state-of-the-art approaches on two benchmark datasets.

cs.CV↗

Design Principles for Self-forming Interfaces Enabling Stable Lithium Metal Anodes

The path toward Li-ion batteries with higher energy-densities will likely involve use of thin lithium metal (Li) anode (<50 $μ$m in thickness), whose cyclability today remains limited by dendrite formation and low Coulombic efficiency. Previous studies have shown that the solid-electrolyte-interface (SEI) of Li metal plays a crucial role in Li electrodeposition and stripping. However, design rules for optimal SEIs on lithium metal are not well-established. Here, using integrated experimental and modeling studies on a series of structurally-similar SEI-modifying compounds as model systems, we reveal the relationship between SEI compositions, Li deposition morphology and coulombic efficiency, and identify two key descriptors (ionicity and compactness) for high performance SEIs through integrated experimental and modeling studies. Using this understanding, we design a highly ionic and compact SEI that shows excellent cycling performance in LiCoO$_2$-Li full cells at practical current densities. Our results provide guidance for the rational selection and optimization of SEI modifiers to further improve Li metal anodes.

physics.app-ph↗

Attention-based Pyramid Aggregation Network for Visual Place Recognition

Visual place recognition is challenging in the urban environment and is usually viewed as a large scale image retrieval task. The intrinsic challenges in place recognition exist that the confusing objects such as cars and trees frequently occur in the complex urban scene, and buildings with repetitive structures may cause over-counting and the burstiness problem degrading the image representations. To address these problems, we present an Attention-based Pyramid Aggregation Network (APANet), which is trained in an end-to-end manner for place recognition. One main component of APANet, the spatial pyramid pooling, can effectively encode the multi-size buildings containing geo-information. The other one, the attention block, is adopted as a region evaluator for suppressing the confusing regional features while highlighting the discriminative ones. When testing, we further propose a simple yet effective PCA power whitening strategy, which significantly improves the widely used PCA whitening by reasonably limiting the impact of over-counting. Experimental evaluations demonstrate that the proposed APANet outperforms the state-of-the-art methods on two place recognition benchmarks, and generalizes well on standard image retrieval datasets.

cs.CV↗

Breaking Pauli blockade via ultrafast cooling of hot electrons in optically-pumped graphene

Pauli blockade occurs when the excited electrons fill up the states near the conduction bands and block subsequent absorption in semiconductors, and has been widely applied in mode-locking for passively-pulsed-laser systems. In this letter, we report the first direct observation that the Pauli blockade is broken by ultrafast cooling of hot electrons in optically-pumped graphene. With femtosecond spectroscopy, we demonstrate that the time scale to excite an electron (~100 fs) is of the same order as that of the electron decay via electron-electron scattering, which allows the electron excitation interplays strongly with the cooling of hot electrons. Consequently, Pauli blockade is dismissed, leading to an unconventionally enhanced optical absorption. We suggest that this effect is a universal feature of two-dimensional layered materials, which sheds the light of ultrafast carrier dynamics in nonlinear physics and inspires the designing of new-generation of ultrafast optoelectronic devices.

physics.optics↗

A Probabilistic Disease Progression Model for Predicting Future Clinical Outcome

In this work, we consider the problem of predicting the course of a progressive disease, such as cancer or Alzheimer's. Progressive diseases often start with mild symptoms that might precede a diagnosis, and each patient follows their own trajectory. Patient trajectories exhibit wild variability, which can be associated with many factors such as genotype, age, or sex. An additional layer of complexity is that, in real life, the amount and type of data available for each patient can differ significantly. For example, for one patient we might have no prior history, whereas for another patient we might have detailed clinical assessments obtained at multiple prior time-points. This paper presents a probabilistic model that can handle multiple modalities (including images and clinical assessments) and variable patient histories with irregular timings and missing entries, to predict clinical scores at future time-points. We use a sigmoidal function to model latent disease progression, which gives rise to clinical observations in our generative model. We implemented an approximate Bayesian inference strategy on the proposed model to estimate the parameters on data from a large population of subjects. Furthermore, the Bayesian framework enables the model to automatically fine-tune its predictions based on historical observations that might be available on the test subject. We applied our method to a longitudinal Alzheimer's disease dataset with more than 3000 subjects [23] and present a detailed empirical analysis of prediction performance under different scenarios, with comparisons against several benchmarks. We also demonstrate how the proposed model can be interrogated to glean insights about temporal dynamics in Alzheimer's disease.

cs.LG↗