arXiv subjects

Yixuan Dong

Publications and source records attributed to Yixuan Dong.

5 recordsLinked to original sources

arXiv2026

DMT-Dens: Density-preserving manifold visualization for biological data

Motivation: Low-dimensional embeddings are widely used to explore cell-state heterogeneity in single-cell and other high-dimensional biological data. Although many methods preserve local neighborhoods, they may distort the apparent sampling density of processed observations, altering the visual contrast between dense and sparse regions and complicating the interpretation of rare, transitional, or continuous cell-state populations. Results: We present DMT-Dens, a parametric manifold-visualization method built on a latent-token Transformer encoder. The model integrates rank-based manifold alignment with hard-pair aggregation. To preserve density, it optimizes a loss based on the Pearson correlation between k-nearest-neighbor log-radius estimates in the processed input and two-dimensional embedding spaces. Benchmark evaluations demonstrate strong density preservation, particularly on biological datasets, while retaining competitive label separability. Availability: Source code, data-processing scripts, and resolved experiment configurations are available at https://github.com/Ruizhe-wang/DMT-Dens.

q-bio.QM↗

arXiv2026

Proxy Avatar Meets Low-Rank Caching: Real-Time One-Shot Emotion-Controllable Portrait Animation

Audio-driven portrait animation has advanced rapidly with diffusion-based generative models, yet real-time one-shot generation with expressive emotion control remains challenging. Existing methods often suffer from insufficient emotion-aware motion priors and expensive appearance computation during multi-step denoising. To address these issues, we propose Proxy Avatar Meets Low-Rank Caching, a cascaded framework for real-time one-shot emotion-controllable portrait animation. Instead of directly generating the target portrait from audio, our method uses a Gaussian-based emotion proxy avatar as a reusable motion generator, which is trained once on a single identity to produce expressive driving videos from audio and emotion labels. Since the proxy avatar only provides motion rather than target appearance or geometry, a large-scale one-shot retargeting model further extracts identity-independent motion from the proxy performance and adapts it to arbitrary target portraits. To improve inference efficiency, we introduce zero-shot appearance reuse with low-rank caching, which caches reference appearance features at the initial denoising step and models subsequent feature variations using lightweight low-rank adapters. Extensive experiments demonstrate that our method achieves stronger emotional expressiveness, better identity-preserving animation, and substantially reduced inference cost, enabling real-time one-shot portrait animation.

cs.CV↗

arXiv2026

GaussianEmoTalker: Real-Time Emotional Talking Head Synthesis with Audio-Driven and Blendshape-Based 3D Gaussian Splatting

Audio-driven talking head synthesis has achieved impressive progress in lip synchronization and visual quality, yet generating expressive emotional avatars with controllable intensity remains challenging, especially under real-time constraints. In this paper, we present GaussianEmoTalker, an audio-driven framework for real-time emotional talking head synthesis based on 3D Gaussian Splatting. Instead of directly predicting the final emotional avatar from speech, we formulate emotional animation as a neutral-to-emotional residual deformation problem. GaussianEmoTalker first constructs an identity-specific neutral talking space with GaussianBlendshapes, which provides high-fidelity Gaussian attributes and phoneme-synchronized neutral motion. It then predicts an emotion-conditioned residual deformation by combining mesh displacement cues, audio features, emotion categories, and intensity encodings. To fuse these heterogeneous signals, we introduce a spatial-audio-emotion attention module that estimates the offsets of Gaussian attributes for expressive and temporally stable rendering. Extensive experiments demonstrate that GaussianEmoTalker achieves competitive video quality, accurate lip synchronization, controllable emotional expression, and real-time rendering compared with recent emotional talking head methods. Our project page is available at https://njust-yang.github.io/GaussianEmoTalker.github.io/

cs.CV↗

arXiv2026

CellScientist: Dual-Space Hierarchical Orchestration for Closed-Loop Refinement of Virtual Cell Models

Virtual Cell Modeling (VCM) requires models that not only predict perturbation responses, but also support targeted revision when predictions fail. Current LLM-assisted modeling workflows face a refinement-routing problem: prediction discrepancies are observed through executable implementations, but the relevant revision may involve the modeling assumption, representation design, implementation, or task constraint. Without structured feedback propagation across these levels, iterative refinement may repair code while failing to revise the assumption responsible for the discrepancy. We propose CellScientist, a dual-space hierarchical framework that couples a high-level hypothesis space with a low-level executable implementation space. CellScientist represents modeling decisions as structured states, realizes them as admissible programs under task and interface constraints, and routes execution discrepancies back to targeted hypothesis or implementation updates. This enables a closed Hypothesis -> Implementation -> Hypothesis loop where failures become structured signals for model refinement rather than debugging events. Across morphology and transcriptomic benchmarks, with additional single-cell perturbation evaluations, the final executable models selected by CellScientist improve over reference baselines under fixed split and evaluation protocols, while the workflow produces auditable refinement traces.

cs.LG↗

arXiv2025

SGD-Mix: Enhancing Domain-Specific Image Classification with Label-Preserving Data Augmentation

Data augmentation for domain-specific image classification tasks often struggles to simultaneously address diversity, faithfulness, and label clarity of generated data, leading to suboptimal performance in downstream tasks. While existing generative diffusion model-based methods aim to enhance augmentation, they fail to cohesively tackle these three critical aspects and often overlook intrinsic challenges of diffusion models, such as sensitivity to model characteristics and stochasticity under strong transformations. In this paper, we propose a novel framework that explicitly integrates diversity, faithfulness, and label clarity into the augmentation process. Our approach employs saliency-guided mixing and a fine-tuned diffusion model to preserve foreground semantics, enrich background diversity, and ensure label consistency, while mitigating diffusion model limitations. Extensive experiments across fine-grained, long-tail, few-shot, and background robustness tasks demonstrate our method's superior performance over state-of-the-art approaches.

cs.CV↗