arXiv subjects

Yizhe Wang

Publications and source records attributed to Yizhe Wang.

9 recordsLinked to original sources

arXiv2026

Disentangling Acoustic Cues in Alzheimer's Pathology and Perception: The Roles of Language and Gender

Acoustic biomarkers show promise for detecting Alzheimer's Disease (AD), yet whether the cues driving diagnostic AI align with those salient to human listeners is underexplored across languages and genders, where pathological markers and perceptual strategies differ. We train models to predict clinical AD status (pathology) and human perceptual scores across Mandarin and Greek, male and female speakers. Using SHAP for interpretability and statistical models for validation, we compare feature importance by subgroup. Results reveal a context-dependent divergence: pathological-perceptual alignment is significant for Mandarin and female speakers but disappears for Greek and male speakers, where pathology models did not exceed chance; this is a failure mode that population-specific auditing surfaces. Global Explainable AI (XAI) explanations can mask critical demographic divergences, highlighting the need for population-specific explainability auditing for equitable deployment of clinical speech AI.

cs.SD↗

arXiv2026

A Scale-adaptive Vision Model Links C. elegans Neuronal Morphology to Behavior for Neurotoxicity Assessment

Neurological disorders are a leading cause of global disability and are increasingly linked to environmental chemical exposures. Yet neurotoxicity assessment still relies on hand-scored morphological readouts that are subjective and poorly predictive of behavioral outcomes. Caenorhabditis elegans provides a genetically tractable, 3R-compliant alternative, but quantifying neuronal phenotypes from confocal microscopy at scale remains computationally challenging: existing vision foundation models, trained on natural or radiological images, cannot resolve the sparse signals and multi-scale lesions of neuronal imaging. Here, we introduce a dedicated self-supervised vision model for C. elegans dopaminergic neurons, together with CeNeuMorph, a multi-grained confocal benchmark of 27,117 annotated images. Specifically, moving beyond standard Masked Autoencoders, we propose a scale-adaptive masked image modeling strategy that jointly learns representations across resolutions and patch sizes under a fixed token budget. By decoupling structural semantic learning from rigid grid constraints, the model effectively resolves the full spectrum of neurodegenerative lesions - ranging from fine dendritic beading to gross soma shrinkage - within a tractable computational framework. Finally, our model surpasses both generalist and biomedical foundation models across classification, segmentation and detection tasks. Fusing visual features with morphological descriptors enables prediction of dopamine-dependent behavioral deficits ($R^2=0.498$). Screening 180 agrochemicals, we identify the benzimidazole moiety as a previously unrecognized determinant of dopaminergic neurotoxicity. Together, the work demonstrates how scale-adaptive self-supervised learning can connect morphology to function for a scalable alternative to mammalian in vivo models for neurotoxicity assessment and drug discovery.

cs.CE↗

arXiv2025

Electronic origin of reorganization energy in interfacial electron transfer

Electron transfer (ET) reactions underpin energy conversion and chemical transformations in both biological and abiological systems. The efficiency of any ET process relies on achieving a desired ET rate within an optimal driving force range. Marcus theory provides a microscopic framework for understanding the activation free energy, and thus the rate, of ET in terms of a key parameter: the reorganization energy. For electrified solid-liquid interfaces, it has long been conventionally understood that only factors in the electrolyte phase are responsible for determining the reorganization energy and the electronic density of states (DOS) of the electrode serves only to dictate the number of thermally accessible channels for ET. Here we show instead that the electrode DOS plays a central role in governing the reorganization energy, far outweighing its conventionally assumed role. Using atomically layered heterostructures, we tune the DOS of graphene and measure outer-sphere ET kinetics. We find the ensuing variation in ET rate arises from strong modulation in a reorganization energy associated with image potential localization in the electrode. This work redefines the traditional paradigm of heterogeneous ET kinetics, revealing a deeper role of the electrode electronic structure in interfacial reactivity.

cond-mat.mtrl-sci↗

arXiv2025

BP-GPT: Auditory Neural Decoding Using fMRI-prompted LLM

Decoding language information from brain signals represents a vital research area within brain-computer interfaces, particularly in the context of deciphering the semantic information from the fMRI signal. Although existing work uses LLM to achieve this goal, their method does not use an end-to-end approach and avoids the LLM in the mapping of fMRI-to-text, leaving space for the exploration of the LLM in auditory decoding. In this paper, we introduce a novel method, the Brain Prompt GPT (BP-GPT). By using the brain representation that is extracted from the fMRI as a prompt, our method can utilize GPT-2 to decode fMRI signals into stimulus text. Further, we introduce the text prompt and align the fMRI prompt to it. By introducing the text prompt, our BP-GPT can extract a more robust brain prompt and promote the decoding of pre-trained LLM. We evaluate our BP-GPT on the open-source auditory semantic decoding dataset and achieve a significant improvement up to 4.61 on METEOR and 2.43 on BERTScore across all the subjects compared to the state-of-the-art method. The experimental results demonstrate that using brain representation as a prompt to further drive LLM for auditory neural decoding is feasible and effective. The code is available at https://github.com/1994cxy/BP-GPT.

cs.HC↗

arXiv2024

Open-vocabulary Auditory Neural Decoding Using fMRI-prompted LLM

Decoding language information from brain signals represents a vital research area within brain-computer interfaces, particularly in the context of deciphering the semantic information from the fMRI signal. However, many existing efforts concentrate on decoding small vocabulary sets, leaving space for the exploration of open vocabulary continuous text decoding. In this paper, we introduce a novel method, the \textbf{Brain Prompt GPT (BP-GPT)}. By using the brain representation that is extracted from the fMRI as a prompt, our method can utilize GPT-2 to decode fMRI signals into stimulus text. Further, we introduce a text-to-text baseline and align the fMRI prompt to the text prompt. By introducing the text-to-text baseline, our BP-GPT can extract a more robust brain prompt and promote the decoding of pre-trained LLM. We evaluate our BP-GPT on the open-source auditory semantic decoding dataset and achieve a significant improvement up to $4.61\%$ on METEOR and $2.43\%$ on BERTScore across all the subjects compared to the state-of-the-art method. The experimental results demonstrate that using brain representation as a prompt to further drive LLM for auditory neural decoding is feasible and effective.

cs.HC↗

arXiv2023

A Novel Scholar Embedding Model for Interdisciplinary Collaboration

Interdisciplinary collaboration has become a driving force for scientific breakthroughs, and evaluating scholars' performance in interdisciplinary researches is essential for promoting such collaborations. However, traditional scholar evaluation methods based solely on individual achievements do not consider interdisciplinary cooperation, creating a challenge for interdisciplinary scholar evaluation and recommendation. To address this issue, we propose a scholar embedding model that quantifies and represents scholars based on global semantic information and social influence, enabling real-time tracking of scholars' research trends. Our model incorporates semantic information and social influence for interdisciplinary scholar evaluation, laying the foundation for future interdisciplinary collaboration discovery and recommendation projects. We demonstrate the effectiveness of our model on a sample of scholars from the Beijing University of Posts and Telecommunications.

cs.DL↗

arXiv2023

Recover Triggered States: Protect Model Against Backdoor Attack in Reinforcement Learning

A backdoor attack allows a malicious user to manipulate the environment or corrupt the training data, thus inserting a backdoor into the trained agent. Such attacks compromise the RL system's reliability, leading to potentially catastrophic results in various key fields. In contrast, relatively limited research has investigated effective defenses against backdoor attacks in RL. This paper proposes the Recovery Triggered States (RTS) method, a novel approach that effectively protects the victim agents from backdoor attacks. RTS involves building a surrogate network to approximate the dynamics model. Developers can then recover the environment from the triggered state to a clean state, thereby preventing attackers from activating backdoors hidden in the agent by presenting the trigger. When training the surrogate to predict states, we incorporate agent action information to reduce the discrepancy between the actions taken by the agent on predicted states and the actions taken on real states. RTS is the first approach to defend against backdoor attacks in a single-agent setting. Our results show that using RTS, the cumulative reward only decreased by 1.41% under the backdoor attack.

cs.LG↗

arXiv2023

Co-Occurrence Matters: Learning Action Relation for Temporal Action Localization

Temporal action localization (TAL) is a prevailing task due to its great application potential. Existing works in this field mainly suffer from two weaknesses: (1) They often neglect the multi-label case and only focus on temporal modeling. (2) They ignore the semantic information in class labels and only use the visual information. To solve these problems, we propose a novel Co-Occurrence Relation Module (CORM) that explicitly models the co-occurrence relationship between actions. Besides the visual information, it further utilizes the semantic embeddings of class labels to model the co-occurrence relationship. The CORM works in a plug-and-play manner and can be easily incorporated with the existing sequence models. By considering both visual and semantic co-occurrence, our method achieves high multi-label relationship modeling capacity. Meanwhile, existing datasets in TAL always focus on low-semantic atomic actions. Thus we construct a challenging multi-label dataset UCF-Crime-TAL that focuses on high-semantic actions by annotating the UCF-Crime dataset at frame level and considering the semantic overlap of different events. Extensive experiments on two commonly used TAL datasets, \textit{i.e.}, MultiTHUMOS and TSU, and our newly proposed UCF-Crime-TAL demenstrate the effectiveness of the proposed CORM, which achieves state-of-the-art performance on these datasets.

cs.CV↗

arXiv2019

Application of Time Series Analysis to Traffic Accidents in Los Angeles

With the improvements of Los Angeles in many aspects, people in mounting numbers tend to live or travel to the city. The primary objective of this paper is to apply a set of methods for the time series analysis of traffic accidents in Los Angeles in the past few years. The number of traffic accidents, collected from 2010 to 2019 monthly reveals that the traffic accident happens seasonally and increasing with fluctuation. This paper utilizes the ensemble methods to combine several different methods to model the data from various perspectives, which can lead to better forecasting accuracy. The IMA(1, 1), ETS(A, N, A), and two models with Fourier items are failed in independence assumption checking. However, the Online Gradient Descent (OGD) model generated by the ensemble method shows the perfect fit in the data modeling, which is the state-of-the-art model among our candidate models. Therefore, it can be easier to accurately forecast future traffic accidents based on previous data through our model, which can help designers to make better plans.

stat.AP↗