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Yizhuo Wang

Publications and source records attributed to Yizhuo Wang.

22 records · Page 2Linked to original sources

On the Mathematics of RNA Velocity II: Algorithmic Aspects

In a previous paper [CSIAM Trans. Appl. Math. 2 (2021), 1-55], the authors proposed a theoretical framework for the analysis of RNA velocity, which is a promising concept in scRNA-seq data analysis to reveal the cell state-transition dynamical processes underlying snapshot data. The current paper is devoted to the algorithmic study of some key components in RNA velocity workflow. Four important points are addressed in this paper: (1) We construct a rational time-scale fixation method which can determine the global gene-shared latent time for cells. (2) We present an uncertainty quantification strategy for the inferred parameters obtained through the EM algorithm. (3) We establish the optimal criterion for the choice of velocity kernel bandwidth with respect to the sample size in the downstream analysis and discuss its implications. (4) We propose a temporal distance estimation approach between two cell clusters along the cellular development path. Some illustrative numerical tests are also carried out to verify our analysis. These results are intended to provide tools and insights in further development of RNA velocity type methods in the future.

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Spatio-Temporal Attention Network for Persistent Monitoring of Multiple Mobile Targets

This work focuses on the persistent monitoring problem, where a set of targets moving based on an unknown model must be monitored by an autonomous mobile robot with a limited sensing range. To keep each target's position estimate as accurate as possible, the robot needs to adaptively plan its path to (re-)visit all the targets and update its belief from measurements collected along the way. In doing so, the main challenge is to strike a balance between exploitation, i.e., re-visiting previously-located targets, and exploration, i.e., finding new targets or re-acquiring lost ones. Encouraged by recent advances in deep reinforcement learning, we introduce an attention-based neural solution to the persistent monitoring problem, where the agent can learn the inter-dependencies between targets, i.e., their spatial and temporal correlations, conditioned on past measurements. This endows the agent with the ability to determine which target, time, and location to attend to across multiple scales, which we show also helps relax the usual limitations of a finite target set. We experimentally demonstrate that our method outperforms other baselines in terms of number of targets visits and average estimation error in complex environments. Finally, we implement and validate our model in a drone-based simulation experiment to monitor mobile ground targets in a high-fidelity simulator.

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ARiADNE: A Reinforcement learning approach using Attention-based Deep Networks for Exploration

In autonomous robot exploration tasks, a mobile robot needs to actively explore and map an unknown environment as fast as possible. Since the environment is being revealed during exploration, the robot needs to frequently re-plan its path online, as new information is acquired by onboard sensors and used to update its partial map. While state-of-the-art exploration planners are frontier- and sampling-based, encouraged by the recent development in deep reinforcement learning (DRL), we propose ARiADNE, an attention-based neural approach to obtain real-time, non-myopic path planning for autonomous exploration. ARiADNE is able to learn dependencies at multiple spatial scales between areas of the agent's partial map, and implicitly predict potential gains associated with exploring those areas. This allows the agent to sequence movement actions that balance the natural trade-off between exploitation/refinement of the map in known areas and exploration of new areas. We experimentally demonstrate that our method outperforms both learning and non-learning state-of-the-art baselines in terms of average trajectory length to complete exploration in hundreds of simplified 2D indoor scenarios. We further validate our approach in high-fidelity Robot Operating System (ROS) simulations, where we consider a real sensor model and a realistic low-level motion controller, toward deployment on real robots.

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DL-Traff: Survey and Benchmark of Deep Learning Models for Urban Traffic Prediction

Nowadays, with the rapid development of IoT (Internet of Things) and CPS (Cyber-Physical Systems) technologies, big spatiotemporal data are being generated from mobile phones, car navigation systems, and traffic sensors. By leveraging state-of-the-art deep learning technologies on such data, urban traffic prediction has drawn a lot of attention in AI and Intelligent Transportation System community. The problem can be uniformly modeled with a 3D tensor (T, N, C), where T denotes the total time steps, N denotes the size of the spatial domain (i.e., mesh-grids or graph-nodes), and C denotes the channels of information. According to the specific modeling strategy, the state-of-the-art deep learning models can be divided into three categories: grid-based, graph-based, and multivariate time-series models. In this study, we first synthetically review the deep traffic models as well as the widely used datasets, then build a standard benchmark to comprehensively evaluate their performances with the same settings and metrics. Our study named DL-Traff is implemented with two most popular deep learning frameworks, i.e., TensorFlow and PyTorch, which is already publicly available as two GitHub repositories https://github.com/deepkashiwa20/DL-Traff-Grid and https://github.com/deepkashiwa20/DL-Traff-Graph. With DL-Traff, we hope to deliver a useful resource to researchers who are interested in spatiotemporal data analysis.

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