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Yongbing Zhang

Publications and source records attributed to Yongbing Zhang.

At least 37 records · Page 2Linked to original sources

D3C2-Net: Dual-Domain Deep Convolutional Coding Network for Compressive Sensing

By mapping iterative optimization algorithms into neural networks (NNs), deep unfolding networks (DUNs) exhibit well-defined and interpretable structures and achieve remarkable success in the field of compressive sensing (CS). However, most existing DUNs solely rely on the image-domain unfolding, which restricts the information transmission capacity and reconstruction flexibility, leading to their loss of image details and unsatisfactory performance. To overcome these limitations, this paper develops a dual-domain optimization framework that combines the priors of (1) image- and (2) convolutional-coding-domains and offers generality to CS and other inverse imaging tasks. By converting this optimization framework into deep NN structures, we present a Dual-Domain Deep Convolutional Coding Network (D3C2-Net), which enjoys the ability to efficiently transmit high-capacity self-adaptive convolutional features across all its unfolded stages. Our theoretical analyses and experiments on simulated and real captured data, covering 2D and 3D natural, medical, and scientific signals, demonstrate the effectiveness, practicality, superior performance, and generalization ability of our method over other competing approaches and its significant potential in achieving a balance among accuracy, complexity, and interpretability. Code is available at https://github.com/lwq20020127/D3C2-Net.

cs.CV↗

Category Prompt Mamba Network for Nuclei Segmentation and Classification

Nuclei segmentation and classification provide an essential basis for tumor immune microenvironment analysis. The previous nuclei segmentation and classification models require splitting large images into smaller patches for training, leading to two significant issues. First, nuclei at the borders of adjacent patches often misalign during inference. Second, this patch-based approach significantly increases the model's training and inference time. Recently, Mamba has garnered attention for its ability to model large-scale images with linear time complexity and low memory consumption. It offers a promising solution for training nuclei segmentation and classification models on full-sized images. However, the Mamba orientation-based scanning method lacks account for category-specific features, resulting in sub-optimal performance in scenarios with imbalanced class distributions. To address these challenges, this paper introduces a novel scanning strategy based on category probability sorting, which independently ranks and scans features for each category according to confidence from high to low. This approach enhances the feature representation of uncertain samples and mitigates the issues caused by imbalanced distributions. Extensive experiments conducted on four public datasets demonstrate that our method outperforms state-of-the-art approaches, delivering superior performance in nuclei segmentation and classification tasks.

cs.CV↗

Prototype-Guided Cross-Modal Knowledge Enhancement for Adaptive Survival Prediction

Histo-genomic multimodal survival prediction has garnered growing attention for its remarkable model performance and potential contributions to precision medicine. However, a significant challenge in clinical practice arises when only unimodal data is available, limiting the usability of these advanced multimodal methods. To address this issue, this study proposes a prototype-guided cross-modal knowledge enhancement (ProSurv) framework, which eliminates the dependency on paired data and enables robust learning and adaptive survival prediction. Specifically, we first introduce an intra-modal updating mechanism to construct modality-specific prototype banks that encapsulate the statistics of the whole training set and preserve the modality-specific risk-relevant features/prototypes across intervals. Subsequently, the proposed cross-modal translation module utilizes the learned prototypes to enhance knowledge representation for multimodal inputs and generate features for missing modalities, ensuring robust and adaptive survival prediction across diverse scenarios. Extensive experiments on four public datasets demonstrate the superiority of ProSurv over state-of-the-art methods using either unimodal or multimodal input, and the ablation study underscores its feasibility for broad applicability. Overall, this study addresses a critical practical challenge in computational pathology, offering substantial significance and potential impact in the field.

cs.LG↗

Fast and Accurate Gigapixel Pathological Image Classification with Hierarchical Distillation Multi-Instance Learning

Although multi-instance learning (MIL) has succeeded in pathological image classification, it faces the challenge of high inference costs due to processing numerous patches from gigapixel whole slide images (WSIs). To address this, we propose HDMIL, a hierarchical distillation multi-instance learning framework that achieves fast and accurate classification by eliminating irrelevant patches. HDMIL consists of two key components: the dynamic multi-instance network (DMIN) and the lightweight instance pre-screening network (LIPN). DMIN operates on high-resolution WSIs, while LIPN operates on the corresponding low-resolution counterparts. During training, DMIN are trained for WSI classification while generating attention-score-based masks that indicate irrelevant patches. These masks then guide the training of LIPN to predict the relevance of each low-resolution patch. During testing, LIPN first determines the useful regions within low-resolution WSIs, which indirectly enables us to eliminate irrelevant regions in high-resolution WSIs, thereby reducing inference time without causing performance degradation. In addition, we further design the first Chebyshev-polynomials-based Kolmogorov-Arnold classifier in computational pathology, which enhances the performance of HDMIL through learnable activation layers. Extensive experiments on three public datasets demonstrate that HDMIL outperforms previous state-of-the-art methods, e.g., achieving improvements of 3.13% in AUC while reducing inference time by 28.6% on the Camelyon16 dataset.

cs.CV↗

DAWN: Domain-Adaptive Weakly Supervised Nuclei Segmentation via Cross-Task Interactions

Weakly supervised segmentation methods have gained significant attention due to their ability to reduce the reliance on costly pixel-level annotations during model training. However, the current weakly supervised nuclei segmentation approaches typically follow a two-stage pseudo-label generation and network training process. The performance of the nuclei segmentation heavily relies on the quality of the generated pseudo-labels, thereby limiting its effectiveness. This paper introduces a novel domain-adaptive weakly supervised nuclei segmentation framework using cross-task interaction strategies to overcome the challenge of pseudo-label generation. Specifically, we utilize weakly annotated data to train an auxiliary detection task, which assists the domain adaptation of the segmentation network. To enhance the efficiency of domain adaptation, we design a consistent feature constraint module integrating prior knowledge from the source domain. Furthermore, we develop pseudo-label optimization and interactive training methods to improve the domain transfer capability. To validate the effectiveness of our proposed method, we conduct extensive comparative and ablation experiments on six datasets. The results demonstrate the superiority of our approach over existing weakly supervised approaches. Remarkably, our method achieves comparable or even better performance than fully supervised methods. Our code will be released in https://github.com/zhangye-zoe/DAWN.

eess.IV↗

HisynSeg: Weakly-Supervised Histopathological Image Segmentation via Image-Mixing Synthesis and Consistency Regularization

Tissue semantic segmentation is one of the key tasks in computational pathology. To avoid the expensive and laborious acquisition of pixel-level annotations, a wide range of studies attempt to adopt the class activation map (CAM), a weakly-supervised learning scheme, to achieve pixel-level tissue segmentation. However, CAM-based methods are prone to suffer from under-activation and over-activation issues, leading to poor segmentation performance. To address this problem, we propose a novel weakly-supervised semantic segmentation framework for histopathological images based on image-mixing synthesis and consistency regularization, dubbed HisynSeg. Specifically, synthesized histopathological images with pixel-level masks are generated for fully-supervised model training, where two synthesis strategies are proposed based on Mosaic transformation and Bézier mask generation. Besides, an image filtering module is developed to guarantee the authenticity of the synthesized images. In order to further avoid the model overfitting to the occasional synthesis artifacts, we additionally propose a novel self-supervised consistency regularization, which enables the real images without segmentation masks to supervise the training of the segmentation model. By integrating the proposed techniques, the HisynSeg framework successfully transforms the weakly-supervised semantic segmentation problem into a fully-supervised one, greatly improving the segmentation accuracy. Experimental results on three datasets prove that the proposed method achieves a state-of-the-art performance. Code is available at https://github.com/Vison307/HisynSeg.

cs.CV↗

Efficient Self-Supervised Video Hashing with Selective State Spaces

Self-supervised video hashing (SSVH) is a practical task in video indexing and retrieval. Although Transformers are predominant in SSVH for their impressive temporal modeling capabilities, they often suffer from computational and memory inefficiencies. Drawing inspiration from Mamba, an advanced state-space model, we explore its potential in SSVH to achieve a better balance between efficacy and efficiency. We introduce S5VH, a Mamba-based video hashing model with an improved self-supervised learning paradigm. Specifically, we design bidirectional Mamba layers for both the encoder and decoder, which are effective and efficient in capturing temporal relationships thanks to the data-dependent selective scanning mechanism with linear complexity. In our learning strategy, we transform global semantics in the feature space into semantically consistent and discriminative hash centers, followed by a center alignment loss as a global learning signal. Our self-local-global (SLG) paradigm significantly improves learning efficiency, leading to faster and better convergence. Extensive experiments demonstrate S5VH's improvements over state-of-the-art methods, superior transferability, and scalable advantages in inference efficiency. Code is available at https://github.com/gimpong/AAAI25-S5VH.

cs.CV↗

MamMIL: Multiple Instance Learning for Whole Slide Images with State Space Models

Recently, pathological diagnosis has achieved superior performance by combining deep learning models with the multiple instance learning (MIL) framework using whole slide images (WSIs). However, the giga-pixeled nature of WSIs poses a great challenge for efficient MIL. Existing studies either do not consider global dependencies among instances, or use approximations such as linear attentions to model the pair-to-pair instance interactions, which inevitably brings performance bottlenecks. To tackle this challenge, we propose a framework named MamMIL for WSI analysis by cooperating the selective structured state space model (i.e., Mamba) with MIL, enabling the modeling of global instance dependencies while maintaining linear complexity. Specifically, considering the irregularity of the tissue regions in WSIs, we represent each WSI as an undirected graph. To address the problem that Mamba can only process 1D sequences, we further propose a topology-aware scanning mechanism to serialize the WSI graphs while preserving the topological relationships among the instances. Finally, in order to further perceive the topological structures among the instances and incorporate short-range feature interactions, we propose an instance aggregation block based on graph neural networks. Experiments show that MamMIL can achieve advanced performance than the state-of-the-art frameworks. The code can be accessed at https://github.com/Vison307/MamMIL.

cs.CV↗

A Mixed-Language Multi-Document News Summarization Dataset and a Graphs-Based Extract-Generate Model

Existing research on news summarization primarily focuses on single-language single-document (SLSD), single-language multi-document (SLMD) or cross-language single-document (CLSD). However, in real-world scenarios, news about a international event often involves multiple documents in different languages, i.e., mixed-language multi-document (MLMD). Therefore, summarizing MLMD news is of great significance. However, the lack of datasets for MLMD news summarization has constrained the development of research in this area. To fill this gap, we construct a mixed-language multi-document news summarization dataset (MLMD-news), which contains four different languages and 10,992 source document cluster and target summary pairs. Additionally, we propose a graph-based extract-generate model and benchmark various methods on the MLMD-news dataset and publicly release our dataset and code\footnote[1]{https://github.com/Southnf9/MLMD-news}, aiming to advance research in summarization within MLMD scenarios.

cs.CL↗

GS-Hider: Hiding Messages into 3D Gaussian Splatting

3D Gaussian Splatting (3DGS) has already become the emerging research focus in the fields of 3D scene reconstruction and novel view synthesis. Given that training a 3DGS requires a significant amount of time and computational cost, it is crucial to protect the copyright, integrity, and privacy of such 3D assets. Steganography, as a crucial technique for encrypted transmission and copyright protection, has been extensively studied. However, it still lacks profound exploration targeted at 3DGS. Unlike its predecessor NeRF, 3DGS possesses two distinct features: 1) explicit 3D representation; and 2) real-time rendering speeds. These characteristics result in the 3DGS point cloud files being public and transparent, with each Gaussian point having a clear physical significance. Therefore, ensuring the security and fidelity of the original 3D scene while embedding information into the 3DGS point cloud files is an extremely challenging task. To solve the above-mentioned issue, we first propose a steganography framework for 3DGS, dubbed GS-Hider, which can embed 3D scenes and images into original GS point clouds in an invisible manner and accurately extract the hidden messages. Specifically, we design a coupled secured feature attribute to replace the original 3DGS's spherical harmonics coefficients and then use a scene decoder and a message decoder to disentangle the original RGB scene and the hidden message. Extensive experiments demonstrated that the proposed GS-Hider can effectively conceal multimodal messages without compromising rendering quality and possesses exceptional security, robustness, capacity, and flexibility. Our project is available at: https://xuanyuzhang21.github.io/project/gshider.

cs.CV↗

Self-Supervised Scalable Deep Compressed Sensing

Compressed sensing (CS) is a promising tool for reducing sampling costs. Current deep neural network (NN)-based CS methods face the challenges of collecting labeled measurement-ground truth (GT) data and generalizing to real applications. This paper proposes a novel $\mathbf{S}$elf-supervised s$\mathbf{C}$alable deep CS method, comprising a deep $\mathbf{L}$earning scheme called $\mathbf{SCL}$ and a family of $\mathbf{Net}$works named $\mathbf{SCNet}$, which does not require GT and can handle arbitrary sampling ratios and matrices once trained on a partial measurement set. Our SCL contains a dual-domain loss and a four-stage recovery strategy. The former encourages a cross-consistency on two measurement parts and a sampling-reconstruction cycle-consistency regarding arbitrary ratios and matrices to maximize data/information utilization. The latter can progressively leverage common signal prior in external measurements and internal characteristics of test samples and learned NNs to improve accuracy. SCNet combines both the explicit guidance from optimization algorithms with implicit regularization from advanced NN blocks to learn a collaborative signal representation. Our theoretical analyses and experiments on simulated and real captured data, covering 1-/2-/3-D natural and scientific signals, demonstrate the effectiveness, superior performance, flexibility, and generalization ability of our method over existing self-supervised methods and its significant potential in competing against state-of-the-art supervised methods. Code is available at https://github.com/Guaishou74851/SCNet.

eess.SP↗

Multimodal Cross-Task Interaction for Survival Analysis in Whole Slide Pathological Images

Survival prediction, utilizing pathological images and genomic profiles, is increasingly important in cancer analysis and prognosis. Despite significant progress, precise survival analysis still faces two main challenges: (1) The massive pixels contained in whole slide images (WSIs) complicate the process of pathological images, making it difficult to generate an effective representation of the tumor microenvironment (TME). (2) Existing multimodal methods often rely on alignment strategies to integrate complementary information, which may lead to information loss due to the inherent heterogeneity between pathology and genes. In this paper, we propose a Multimodal Cross-Task Interaction (MCTI) framework to explore the intrinsic correlations between subtype classification and survival analysis tasks. Specifically, to capture TME-related features in WSIs, we leverage the subtype classification task to mine tumor regions. Simultaneously, multi-head attention mechanisms are applied in genomic feature extraction, adaptively performing genes grouping to obtain task-related genomic embedding. With the joint representation of pathological images and genomic data, we further introduce a Transport-Guided Attention (TGA) module that uses optimal transport theory to model the correlation between subtype classification and survival analysis tasks, effectively transferring potential information. Extensive experiments demonstrate the superiority of our approaches, with MCTI outperforming state-of-the-art frameworks on three public benchmarks. \href{https://github.com/jsh0792/MCTI}{https://github.com/jsh0792/MCTI}.

eess.IV↗

Dynamic Pseudo Label Optimization in Point-Supervised Nuclei Segmentation

Deep learning has achieved impressive results in nuclei segmentation, but the massive requirement for pixel-wise labels remains a significant challenge. To alleviate the annotation burden, existing methods generate pseudo masks for model training using point labels. However, the generated masks are inevitably different from the ground truth, and these dissimilarities are not handled reasonably during the network training, resulting in the subpar performance of the segmentation model. To tackle this issue, we propose a framework named DoNuSeg, enabling \textbf{D}ynamic pseudo label \textbf{O}ptimization in point-supervised \textbf{Nu}clei \textbf{Seg}mentation. Specifically, DoNuSeg takes advantage of class activation maps (CAMs) to adaptively capture regions with semantics similar to annotated points. To leverage semantic diversity in the hierarchical feature levels, we design a dynamic selection module to choose the optimal one among CAMs from different encoder blocks as pseudo masks. Meanwhile, a CAM-guided contrastive module is proposed to further enhance the accuracy of pseudo masks. In addition to exploiting the semantic information provided by CAMs, we consider location priors inherent to point labels, developing a task-decoupled structure for effectively differentiating nuclei. Extensive experiments demonstrate that DoNuSeg outperforms state-of-the-art point-supervised methods. The code is available at https://github.com/shinning0821/MICCAI24-DoNuSeg.

cs.CV↗

Protect-Your-IP: Scalable Source-Tracing and Attribution against Personalized Generation

With the advent of personalized generation models, users can more readily create images resembling existing content, heightening the risk of violating portrait rights and intellectual property (IP). Traditional post-hoc detection and source-tracing methods for AI-generated content (AIGC) employ proactive watermark approaches; however, these are less effective against personalized generation models. Moreover, attribution techniques for AIGC rely on passive detection but often struggle to differentiate AIGC from authentic images, presenting a substantial challenge. Integrating these two processes into a cohesive framework not only meets the practical demands for protection and forensics but also improves the effectiveness of attribution tasks. Inspired by this insight, we propose a unified approach for image copyright source-tracing and attribution, introducing an innovative watermarking-attribution method that blends proactive and passive strategies. We embed copyright watermarks into protected images and train a watermark decoder to retrieve copyright information from the outputs of personalized models, using this watermark as an initial step for confirming if an image is AIGC-generated. To pinpoint specific generation techniques, we utilize powerful visual backbone networks for classification. Additionally, we implement an incremental learning strategy to adeptly attribute new personalized models without losing prior knowledge, thereby enhancing the model's adaptability to novel generation methods. We have conducted experiments using various celebrity portrait series sourced online, and the results affirm the efficacy of our method in source-tracing and attribution tasks, as well as its robustness against knowledge forgetting.

cs.CV↗

Rethinking Attention-Based Multiple Instance Learning for Whole-Slide Pathological Image Classification: An Instance Attribute Viewpoint

Multiple instance learning (MIL) is a robust paradigm for whole-slide pathological image (WSI) analysis, processing gigapixel-resolution images with slide-level labels. As pioneering efforts, attention-based MIL (ABMIL) and its variants are increasingly becoming popular due to the characteristics of simultaneously handling clinical diagnosis and tumor localization. However, the attention mechanism exhibits limitations in discriminating between instances, which often misclassifies tissues and potentially impairs MIL performance. This paper proposes an Attribute-Driven MIL (AttriMIL) framework to address these issues. Concretely, we dissect the calculation process of ABMIL and present an attribute scoring mechanism that measures the contribution of each instance to bag prediction effectively, quantifying instance attributes. Based on attribute quantification, we develop a spatial attribute constraint and an attribute ranking constraint to model instance correlations within and across slides, respectively. These constraints encourage the network to capture the spatial correlation and semantic similarity of instances, improving the ability of AttriMIL to distinguish tissue types and identify challenging instances. Additionally, AttriMIL employs a histopathology adaptive backbone that maximizes the pre-trained model's feature extraction capability for collecting pathological features. Extensive experiments on three public benchmarks demonstrate that our AttriMIL outperforms existing state-of-the-art frameworks across multiple evaluation metrics. The implementation code is available at https://github.com/MedCAI/AttriMIL.

cs.CV↗

H2ASeg: Hierarchical Adaptive Interaction and Weighting Network for Tumor Segmentation in PET/CT Images

Positron emission tomography (PET) combined with computed tomography (CT) imaging is routinely used in cancer diagnosis and prognosis by providing complementary information. Automatically segmenting tumors in PET/CT images can significantly improve examination efficiency. Traditional multi-modal segmentation solutions mainly rely on concatenation operations for modality fusion, which fail to effectively model the non-linear dependencies between PET and CT modalities. Recent studies have investigated various approaches to optimize the fusion of modality-specific features for enhancing joint representations. However, modality-specific encoders used in these methods operate independently, inadequately leveraging the synergistic relationships inherent in PET and CT modalities, for example, the complementarity between semantics and structure. To address these issues, we propose a Hierarchical Adaptive Interaction and Weighting Network termed H2ASeg to explore the intrinsic cross-modal correlations and transfer potential complementary information. Specifically, we design a Modality-Cooperative Spatial Attention (MCSA) module that performs intra- and inter-modal interactions globally and locally. Additionally, a Target-Aware Modality Weighting (TAMW) module is developed to highlight tumor-related features within multi-modal features, thereby refining tumor segmentation. By embedding these modules across different layers, H2ASeg can hierarchically model cross-modal correlations, enabling a nuanced understanding of both semantic and structural tumor features. Extensive experiments demonstrate the superiority of H2ASeg, outperforming state-of-the-art methods on AutoPet-II and Hecktor2022 benchmarks. The code is released at https://github.com/JinPLu/H2ASeg.

eess.IV↗

Conformally compact and higher conformal Yang-Mills equations

On conformally compact manifolds we study Yang-Mills equations, their boundary conditions, formal asymptotics, and Dirichlet-to-Neumann maps. We find that smooth solutions with "magnetic" Dirichlet boundary data are obstructed by a conformally invariant, higher order boundary current. We study the asymptotics of the interior Yang-Mills energy functional and show that the obstructing current is the variation of the conformally invariant coefficient of the first log term in this expansion which is a higher derivative conformally invariant analog of the Yang-Mills energy. The invariant energy is the anomaly for the renormalized interior Yang-Mills functional and its variation gives higher conformal Yang-Mills equations. Global solutions to the magnetic boundary problem determine higher order "electric" Neumann data. This yields the Dirichlet-to-Neumann map. We also construct conformally invariant, higher transverse derivative boundary operators. Acting on interior connections, they give obstructions to solving the Yang-Mills boundary problem, determine the asymptotics of formal solutions, and yield conformally invariant tensors capturing the (non-local) electric Neumann data. We also characterize a renormalized Yang-Mills action functional that encodes global features analogously to the renormalized volume for Poincaré-Einstein structures.

math.DG↗

SEINE: Structure Encoding and Interaction Network for Nuclei Instance Segmentation

Nuclei instance segmentation in histopathological images is of great importance for biological analysis and cancer diagnosis but remains challenging for two reasons. (1) Similar visual presentation of intranuclear and extranuclear regions of chromophobe nuclei often causes under-segmentation, and (2) current methods lack the exploration of nuclei structure, resulting in fragmented instance predictions. To address these problems, this paper proposes a structure encoding and interaction network, termed SEINE, which develops the structure modeling scheme of nuclei and exploits the structure similarity between nuclei to improve the integrality of each segmented instance. Concretely, SEINE introduces a contour-based structure encoding (SE) that considers the correlation between nuclei structure and semantics, realizing a reasonable representation of the nuclei structure. Based on the encoding, we propose a structure-guided attention (SGA) module that takes the clear nuclei as prototypes to enhance the structure learning for the fuzzy nuclei. To strengthen the structural learning ability, a semantic feature fusion (SFF) is presented to boost the semantic consistency of semantic and structure branches. Furthermore, a position enhancement (PE) method is applied to suppress incorrect nuclei boundary predictions. Extensive experiments demonstrate the superiority of our approaches, and SEINE achieves state-of-the-art (SOTA) performance on four datasets. The code is available at https://github.com/zhangye-zoe/SEINE.

cs.CV↗