Yoshiki Vazquez-Baeza

arXiv2022

Theoretical Rule-based Knowledge Graph Reasoning by Connectivity Dependency Discovery

Discovering precise and interpretable rules from knowledge graphs is regarded as an essential challenge, which can improve the performances of many downstream tasks and even provide new ways to approach some Natural Language Processing research topics. In this paper, we present a fundamental theory for rule-based knowledge graph reasoning, based on which the connectivity dependencies in the graph are captured via multiple rule types. It is the first time for some of these rule types in a knowledge graph to be considered. Based on these rule types, our theory can provide precise interpretations to unknown triples. Then, we implement our theory by what we call the RuleDict model. Results show that our RuleDict model not only provides precise rules to interpret new triples, but also achieves state-of-the-art performances on one benchmark knowledge graph completion task, and is competitive on other tasks.

cs.CL↗

arXiv2020

Utilizing stability criteria in choosing feature selection methods yields reproducible results in microbiome data

Feature selection is indispensable in microbiome data analysis, but it can be particularly challenging as microbiome data sets are high-dimensional, underdetermined, sparse and compositional. Great efforts have recently been made on developing new methods for feature selection that handle the above data characteristics, but almost all methods were evaluated based on performance of model predictions. However, little attention has been paid to address a fundamental question: how appropriate are those evaluation criteria? Most feature selection methods often control the model fit, but the ability to identify meaningful subsets of features cannot be evaluated simply based on the prediction accuracy. If tiny changes to the training data would lead to large changes in the chosen feature subset, then many of the biological features that an algorithm has found are likely to be a data artifact rather than real biological signal. This crucial need of identifying relevant and reproducible features motivated the reproducibility evaluation criterion such as Stability, which quantifies how robust a method is to perturbations in the data. In our paper, we compare the performance of popular model prediction metric MSE and proposed reproducibility criterion Stability in evaluating four widely used feature selection methods in both simulations and experimental microbiome applications. We conclude that Stability is a preferred feature selection criterion over MSE because it better quantifies the reproducibility of the feature selection method.

q-bio.QM↗