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Yoshiyuki Ishii

Publications and source records attributed to Yoshiyuki Ishii.

3 recordsLinked to original sources

OneComp: One-Line Revolution for Generative AI Model Compression

Deploying foundation models is increasingly constrained by memory footprint, latency, and hardware costs. Post-training compression can mitigate these bottlenecks by reducing the precision of model parameters without significantly degrading performance; however, its practical implementation remains challenging as practitioners navigate a fragmented landscape of quantization algorithms, precision budgets, data-driven calibration strategies, and hardware-dependent execution regimes. We present OneComp, an open-source compression framework that transforms this expert workflow into a reproducible, resource-adaptive pipeline. Given a model identifier and available hardware, OneComp automatically inspects the model, plans mixed-precision assignments, and executes progressive quantization stages, ranging from layer-wise compression to block-wise refinement and global refinement. A key architectural choice is treating the first quantized checkpoint as a deployable pivot, ensuring that each subsequent stage improves the same model and that quality increases as more compute is invested. By converting state-of-the-art compression research into an extensible, open-source, hardware-aware pipeline, OneComp bridges the gap between algorithmic innovation and production-grade model deployment.

cs.LG↗

Deep Mapper: Efficient Visualization of Plausible Conformational Pathways

Acquiring plausible pathways on high-dimensional structural distributions is beneficial in several domains. For example, in the drug discovery field, a protein conformational pathway, i.e. a highly probable sequence of protein structural changes, is useful to analyze interactions between the protein and the ligands, helping to create new drugs. Recently, a state-of-the-art method in drug discovery was presented, which efficiently computes protein pathways using latent variables obtained from an isometric auto-encoding of the space of 3D density maps associated to protein conformations. However, our preliminary experiments show that there is room to significantly reduce the computing time. In this study, we use the Mapper algorithm, which is a Topological Data Analysis method, and present a novel variant to extract plausible conformational pathways from the isometric latent space with comparatively short running time. The extracted pathways are visualized as paths on the resulting Mapper graph. The methodological novelties are described as follows: firstly, the filter function of the Mapper algorithm is optimized so as to extract the pathways via minimization of an energy loss defined on the Mapper graph itself, while filter functions taken in the classical Mapper algorithm are fixed beforehand. The optimization is with respect to parameters of a deep neural network in the filter. Secondly, the clustering method, which defines the vertices and edges of the Mapper graph, of our algorithm, is designed by incorporating domain prior knowledge to assist the extraction. In our numerical experiments, based on an isometric latent space built on the common 50S-ribosomal dataset, the resulting Mapper graph successfully includes all the well-recognized plausible pathways. Moreover, our running time is much shorter than the above state-of-the-art counterpart.

q-bio.QM↗

Optimization of phase-only holograms calculated with scaled diffraction calculation through deep neural networks

Computer-generated holograms (CGHs) are used in holographic three-dimensional (3D) displays and holographic projections. The quality of the reconstructed images using phase-only CGHs is degraded because the amplitude of the reconstructed image is difficult to control. Iterative optimization methods such as the Gerchberg-Saxton (GS) algorithm are one option for improving image quality. They optimize CGHs in an iterative fashion to obtain a higher image quality. However, such iterative computation is time consuming, and the improvement in image quality is often stagnant. Recently, deep learning-based hologram computation has been proposed. Deep neural networks directly infer CGHs from input image data. However, it is limited to reconstructing images that are the same size as the hologram. In this study, we use deep learning to optimize phase-only CGHs generated using scaled diffraction computations and the random phase-free method. By combining the random phase-free method with the scaled diffraction computation, it is possible to handle a zoomable reconstructed image larger than the hologram. In comparison to the GS algorithm, the proposed method optimizes both high quality and speed.

cs.CV↗