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Youngsun Kong

Publications and source records attributed to Youngsun Kong.

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Memory-Efficient EDA Denoising via Knowledge Distillation for Wearable IoT Under Severe Motion Artifacts and Underwater Conditions

Electrodermal activity (EDA) is widely used in wearable Internet of Medical Things (IoMT) systems for continuous health monitoring, including autonomic assessment. However, EDA signals are highly vulnerable to motion artifacts and environmental noise, limiting reliable deployment in harsh operating conditions such as underwater. This study proposes a robust, deployable EDA denoising framework that generalizes across multiple measurement locations and harsh environments. The framework integrates a hybrid CNN-Transformer teacher model with a lightweight depth-wise separable CNN student model via a knowledge distillation (KD) strategy. To further improve robustness, a realistic data augmentation scheme is introduced to simulate diverse motion artifacts and environmental distortions. The KD-based student model significantly reduces model size (7.87 MB to 0.51 MB) and computational cost (105.1M to 11.61M FLOPs) while maintaining denoising performance (MAE: 0.144, SNR improvement: 12.08 dB) using the public dataset validation. In real-world underwater conditions (UMAC dataset) testing, the proposed method substantially improves skin conductance response reconstruction, reducing mean absolute error from 2.809 to 0.215. Furthermore, on independent testing using the CNS-OT dataset, the denoised signals enhanced downstream CNS-OT prediction performance, achieving the highest AUROC (0.806) compared to prior denoising methods. The proposed method also improved the early prediction rate (sensitivity) from 0.550 to 0.767, enabling CNS-OT prediction up to a median of 6.9 minutes before symptom onset. These results demonstrate that the proposed framework not only improves EDA signal quality but also enhances clinically relevant prediction performance while remaining suitable for deployment in resource-constrained wearable Internet of Things systems operating in harsh environments.

eess.SP

ospEDA: Orthogonal Subspace Projection for Electrodermal Activity Decomposition

Electrodermal activity (EDA) is a widely used physiological signal for assessing sympathetic nervous activity, such as arousal, stress, and pain. However, reliable decomposition into tonic and phasic components remains challenging, particularly in noisy environments and across individuals with varying signal morphologies and stimulus responses. We propose ospEDA, a novel Orthogonal Subspace Projection (OSP) based method for EDA decomposition. The method integrates (1) tonic estimation via physiologically motivated valley detection for noise robustness; (2) phasic extraction using OSP to accommodate inter subject variability; and (3) phasic driver estimation through non-negative least squares (NNLS) deconvolution with ridge regularization. We evaluated ospEDA on five real-world datasets and one simulated EDA dataset with ground-truth components, comparing its performance against six existing methods. In simulations with a 20 dB signal to noise ratio (SNR), ospEDA achieved the lowest root mean square error (RMSE) for estimated tonic (0.131) and phasic (0.132) components. Under noisier conditions (10 dB SNR), it maintained superior phasic RMSE (0.293), Pearson correlation (0.782), and R^2 (0.979) values. Furthermore, ospEDA consistently provided the highest F1 scores (0.573, 0.617, 0.638) for sympathetic nerve activity detection across 10, 20, and 30 dB SNR levels, respectively, compared to existing methods. On the real world datasets, ospEDA achieved a stimulus classification AUROC of 0.766 and consistently maintained strong effect sizes (ω^2>0.14) across all five datasets. Overall, ospEDA represents a promising framework for EDA decomposition, showing generally consistent performance and reliable phasic driver estimation under the varying noise conditions, with potential utility for real world physiological monitoring applications.

eess.SP

Autoencoder-Based Denoising of Muscle Artifacts in ECG to Preserve Skin Nerve Activity (SKNA) for Cognitive Stress Detection

The sympathetic nervous system (SNS) plays a central role in regulating the body's responses to stress and maintaining physiological stability. Its dysregulation is associated with a wide range of conditions, from cardiovascular disease to anxiety disorders. Skin nerve activity (SKNA) extracted from high-frequency electrocardiogram (ECG) recordings provides a noninvasive window into SNS dynamics, but its measurement is highly susceptible to electromyographic (EMG) contamination. Traditional preprocessing based on bandpass filtering within a fixed range (e.g., 500--1000 Hz) is susceptible to overlapping EMG and SKNA spectral components, especially during sustained muscle activity. We present a denoising approach using a lightweight one-dimensional convolutional autoencoder with a long short-term memory (LSTM) bottleneck to reconstruct clean SKNA from EMG-contaminated recordings. Using clean ECG-derived SKNA data from cognitive stress experiments and EMG noise from chaotic muscle stimulation recordings, we simulated contamination at realistic noise levels (--4 dB, --8 dB signal-to-noise ratio) and trained the model in the leave-one-subject-out cross-validation framework. The method improved signal-to-noise ratio by up to 9.65 dB, increased cross correlation with clean SKNA from 0.40 to 0.72, and restored burst-based SKNA features to near-clean discriminability (AUROC $\geq$ 0.96). Classification of baseline versus sympathetic stimulation (cognitive stress) conditions reached accuracies of 91--98\% across severe noise levels, comparable to clean data. These results demonstrate that deep learning--based reconstruction can preserve physiologically relevant sympathetic bursts during substantial EMG interference, enabling more robust SKNA monitoring in naturalistic, movement-rich environments.

cs.AI

Feasibility of Extracting Skin Nerve Activity from Electrocardiogram Recorded at A Low Sampling Frequency

Skin nerve activity (SKNA) derived from electrocardiogram (ECG) signals has been a promising non-invasive surrogate for accurate and effective assessment of the sympathetic nervous system (SNS). Typically, SKNA extraction requires a higher sampling frequency than the typical ECG recording requirement (> 2 kHz) because analysis tools extract SKNA from the 0.5-1 kHz frequency band. However, ECG recording systems commonly provide a sampling frequency of 1 kHz or lower, particularly for wearable devices. Our recent power spectral analysis exhibited that 150-500 Hz frequency bands are dominant during sympathetic stimulation. Therefore, we hypothesize that SKNA can be extracted from ECG sampled at a lower sampling frequency. We collected ECG signals from 16 participants during SNS stimulation and resampled the signals at 0.5, 1, and 4 kHz. Our statistical analyses of significance, classification performance, and reliability indicate no significant difference between SKNA indices derived from ECG signals sampled at 0.5, 1, and 4 kHz. Our findings indicate that conventional ECG devices, which are limited to low sampling rates due to resource constraints or outdated guidelines, can be used to reliably collect SKNA if muscle artifact contamination is minimal.

eess.SP

A Novel Approach to Characterize Dynamics of ECG-Derived Skin Nerve Activity via Time-Varying Spectral Analysis

Assessment of the sympathetic nervous system (SNS) is one of the major approaches for studying affective states. Skin nerve activity (SKNA) derived from high-frequency components of electrocardiogram (ECG) signals has been a promising surrogate for assessing the SNS. However, current SKNA analysis tools have shown high variability across study protocols and experiments. Hence, we propose a time-varying spectral approach based on SKNA to assess the SNS with higher sensitivity and reliability. We collected ECG signals at a sampling frequency of 10 KHz from sixteen subjects who underwent various SNS stimulations. Our spectral analysis revealed that frequency bands between 150 - 1,000 Hz showed significant increases in power during SNS stimulations. Using this information, we developed a time-varying index of sympathetic function measurement based on SKNA, termed, Time-Varying Skin Nerve Activity (TVSKNA). TVSKNA is calculated in three steps: time-frequency decomposition, reconstruction using selected frequency bands, and smoothing. TVSKNA indices exhibited generally higher Youden's J, balanced accuracy, and area under the receiver operating characteristic curve, indicating higher sensitivity. The coefficient of variance was lower with TVSKNA indices for most SNS tasks. TVSKNA can serve as a highly sensitive and reliable marker of quantitative assessment of sympathetic function, especially during emotion and stress.

eess.SP

Skin Sympathetic Nerve Activity Driver Extraction through Non-Negative Sparse Decomposition

In recent years, skin sympathetic nerve activity (SKNA) extracted from electrocardiogram has gained attention as a novel noninvasive measure of the sympathetic nervous system (SNS), while electrodermal activity (EDA) has long served this purpose. SparsEDA is a sparse deconvolution technique originally developed for EDA to extract phasic drivers indicating the start of sympathetic burst responses. Our focus is on applying this method to preprocessed SKNA signals, justified by both SKNA and EDA signals' connection to sympathetic nerve activity and prior observed similarities. In a thermal-grill pain experiment, 16 subjects underwent six stimulations each to elicit SNS responses, with simultaneous recording of EDA and SKNA. We confirmed the method's accuracy in identifying stimuli initiation. Results were assessed for burst detection and accuracy of driver placement compared to annotated labels. The SKNA drivers achieved an RMSE of 0.42 from annotated stimulations, a 97% hit rate in detecting applied stimuli, and minimal false alarms during the 2-minute control period and interstimulus intervals.

q-bio.NC

Towards Continuous Skin Sympathetic Nerve Activity Monitoring: Removing Muscle Noise

Continuous monitoring of non-invasive skin sympathetic nerve activity (SKNA) holds promise for understanding the sympathetic nervous system (SNS) dynamics in various physiological and pathological conditions. However, muscle noise artifacts present a challenge in accurate SKNA analysis, particularly in real-life scenarios. This study proposes a deep convolutional neural network (CNN) approach to detect and remove muscle noise from SKNA recordings obtained via ECG electrodes. Twelve healthy participants underwent controlled experimental protocols involving cognitive stress induction and voluntary muscle movements, while collecting SKNA data. Power spectral analysis revealed significant muscle noise interference within the SKNA frequency band (500-1000 Hz). A 2D CNN model was trained on the spectrograms of the data segments to classify them into baseline, stress-induced SKNA, and muscle noise-contaminated periods, achieving an average accuracy of 89.85% across all subjects. Our findings underscore the importance of addressing muscle noise for accurate SKNA monitoring, advancing towards wearable SKNA sensors for real-world applications.

cs.LG

A Preliminary Study on Automatic Motion Artifacts Detection in Electrodermal Activity Data Using Machine Learning

The electrodermal activity (EDA) signal is a sensitive and non-invasive surrogate measure of sympathetic function. Use of EDA has increased in popularity in recent years for such applications as emotion and stress recognition; assessment of pain, fatigue, and sleepiness; diagnosis of depression and epilepsy; and other uses. Recently, there have been several studies using ambulatory EDA recordings, which are often quite useful for analysis of many physiological conditions. Because ambulatory monitoring uses wearable devices, EDA signals are often affected by noise and motion artifacts. An automated noise and motion artifact detection algorithm is therefore of utmost importance for accurate analysis and evaluation of EDA signals. In this paper, we present machine learning-based algorithms for motion artifact detection in EDA signals. With ten subjects, we collected two simultaneous EDA signals from the right and left hands, while instructing the subjects to move only the right hand. Using these data, we proposed a cross-correlation-based approach for non-biased labeling of EDA data segments. A set of statistical, spectral and model-based features were calculated which were then subjected to a feature selection algorithm. Finally, we trained and validated several machine learning methods using a leave-one-subject-out approach. The classification accuracy of the developed model was 83.85% with a standard deviation of 4.91%, which was better than a recent standard method that we considered for comparison to our algorithm.

eess.SP