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Yu Wang

Publications and source records attributed to Yu Wang.

At least 361 records · Page 20Linked to original sources

A predictive modular approach to constraint satisfaction under uncertainty -- with application to glycosylation in continuous monoclonal antibody biosimilar production

The paper proposes a modular-based approach to constraint handling in process optimization and control. This is partly motivated by the recent interest in learning-based methods, e.g., within bioproduction, for which constraint handling under uncertainty is a challenge. The proposed constraint handler, called predictive filter, is combined with an adaptive constraint margin and a constraint violation cost monitor to minimize the cost of violating soft constraints due to model uncertainty and disturbances. The module can be combined with any controller and is based on minimally modifying the controller output, in a least squares sense, such that constraints are satisfied within the considered horizon. The proposed method is computationally efficient and suitable for real-time applications. The effectiveness of the method is illustrated through a realistic case study of glycosylation constraint satisfaction in continuous monoclonal antibody biosimilar production using Chinese hamster ovary cells, employing a metabolic network model consisting of 23 extracellular metabolites and 126 reactions. In the case study, the average constraint-violation cost is reduced by more than 60% compared to the case without the proposed constraint-handling method.

eess.SY↗

Knowledge Homophily in Large Language Models

Large Language Models (LLMs) have been increasingly studied as neural knowledge bases for supporting knowledge-intensive applications such as question answering and fact checking. However, the structural organization of their knowledge remains unexplored. Inspired by cognitive neuroscience findings, such as semantic clustering and priming, where knowing one fact increases the likelihood of recalling related facts, we investigate an analogous knowledge homophily pattern in LLMs. To this end, we map LLM knowledge into a graph representation through knowledge checking at both the triplet and entity levels. After that, we analyze the knowledgeability relationship between an entity and its neighbors, discovering that LLMs tend to possess a similar level of knowledge about entities positioned closer in the graph. Motivated by this homophily principle, we propose a Graph Neural Network (GNN) regression model to estimate entity-level knowledgeability scores for triplets by leveraging their neighborhood scores. The predicted knowledgeability enables us to prioritize checking less well-known triplets, thereby maximizing knowledge coverage under the same labeling budget. This not only improves the efficiency of active labeling for fine-tuning to inject knowledge into LLMs but also enhances multi-hop path retrieval in reasoning-intensive question answering.

cs.LG↗

What Can RL Bring to VLA Generalization? An Empirical Study

Large Vision-Language Action (VLA) models have shown significant potential for embodied AI. However, their predominant training via supervised fine-tuning (SFT) limits generalization due to susceptibility to compounding errors under distribution shifts. Reinforcement learning (RL) offers a path to overcome these limitations by optimizing for task objectives via trial-and-error, yet a systematic understanding of its specific generalization benefits for VLAs compared to SFT is lacking. To address this, our study introduces a comprehensive benchmark for evaluating VLA generalization and systematically investigates the impact of RL fine-tuning across diverse visual, semantic, and execution dimensions. Our extensive experiments reveal that RL fine-tuning, particularly with PPO, significantly enhances generalization in semantic understanding and execution robustness over SFT, while maintaining comparable visual robustness. We identify PPO as a more effective RL algorithm for VLAs than LLM-derived methods like DPO and GRPO. We also develop a simple recipe for efficient PPO training on VLAs, and demonstrate its practical utility for improving VLA generalization. The project page is at https://rlvla.github.io

cs.LG↗

Can LLMs Generate Reliable Test Case Generators? A Study on Competition-Level Programming Problems

Large Language Models (LLMs) have demonstrated remarkable capabilities in code generation, capable of tackling complex tasks during inference. However, the extent to which LLMs can be utilized for code checking or debugging through test case generation remains largely unexplored. We investigate this problem from the perspective of competition-level programming (CP) programs and propose TCGBench, a Benchmark for (LLM generation of) Test Case Generators. This benchmark comprises two tasks, aimed at studying the capabilities of LLMs in (1) generating valid test case generators for a given CP problem, and further (2) generating targeted test case generators that expose bugs in human-written code. Experimental results indicate that while state-of-the-art LLMs can generate valid test case generators in most cases, most LLMs struggle to generate targeted test cases that reveal flaws in human code effectively. Especially, even advanced reasoning models (e.g., o3-mini) fall significantly short of human performance in the task of generating targeted generators. Furthermore, we construct a high-quality, manually curated dataset of instructions for generating targeted generators. Analysis demonstrates that the performance of LLMs can be enhanced with the aid of this dataset, by both prompting and fine-tuning.

cs.CL↗

JuggleRL: Mastering Ball Juggling with a Quadrotor via Deep Reinforcement Learning

Aerial robots interacting with objects must perform precise, contact-rich maneuvers under uncertainty. In this paper, we study the problem of aerial ball juggling using a quadrotor equipped with a racket, a task that demands accurate timing, stable control, and continuous adaptation. We propose JuggleRL, the first reinforcement learning-based system for aerial juggling. It learns closed-loop policies in large-scale simulation using systematic calibration of quadrotor and ball dynamics to reduce the sim-to-real gap. The training incorporates reward shaping to encourage racket-centered hits and sustained juggling, as well as domain randomization over ball position and coefficient of restitution to enhance robustness and transferability. The learned policy outputs mid-level commands executed by a low-level controller and is deployed zero-shot on real hardware, where an enhanced perception module with a lightweight communication protocol reduces delays in high-frequency state estimation and ensures real-time control. Experiments show that JuggleRL achieves an average of $311$ hits over $10$ consecutive trials in the real world, with a maximum of $462$ hits observed, far exceeding a model-based baseline that reaches at most $14$ hits with an average of $3.1$. Moreover, the policy generalizes to unseen conditions, successfully juggling a lighter $5$ g ball with an average of $145.9$ hits. This work demonstrates that reinforcement learning can empower aerial robots with robust and stable control in dynamic interaction tasks.

cs.RO↗

SAC Flow: Sample-Efficient Reinforcement Learning of Flow-Based Policies via Velocity-Reparameterized Sequential Modeling

Training expressive flow-based policies with off-policy reinforcement learning is notoriously unstable due to gradient pathologies in the multi-step action sampling process. We trace this instability to a fundamental connection: the flow rollout is algebraically equivalent to a residual recurrent computation, making it susceptible to the same vanishing and exploding gradients as RNNs. To address this, we reparameterize the velocity network using principles from modern sequential models, introducing two stable architectures: Flow-G, which incorporates a gated velocity, and Flow-T, which utilizes a decoded velocity. We then develop a practical SAC-based algorithm, enabled by a noise-augmented rollout, that facilitates direct end-to-end training of these policies. Our approach supports both from-scratch and offline-to-online learning and achieves state-of-the-art performance on continuous control and robotic manipulation benchmarks, eliminating the need for common workarounds like policy distillation or surrogate objectives.

cs.RO↗

VocalBench: Benchmarking the Vocal Conversational Abilities for Speech Interaction Models

Speech large language models (SpeechLLMs) have extended human-machine interactions from the text modality to the dynamic speech domain. Spoken dialogues convey diverse information, including semantic concepts, acoustic variations, paralanguage cues, and environmental context. However, existing evaluations of speech interaction models lack instances mimicking real scenarios and predominantly focus on the performance of distinct aspects, lacking a comprehensive comparison of critical capabilities between current routines. To address this gap, we propose VocalBench to assess the speech conversational abilities, comprising around 24k carefully curated instances of both English and Mandarin across four key dimensions - semantic quality, acoustic performance, conversational abilities, and robustness, covering 14 user-oriented characters. Experiments on 27 mainstream models reveal the common challenges for current routes, and highlight the need for new insights into next-generation speech interactive systems.

cs.CL↗

Memory in the Age of AI Agents

Memory has emerged, and will continue to remain, a core capability of foundation model-based agents. As research on agent memory rapidly expands and attracts unprecedented attention, the field has also become increasingly fragmented. Existing works that fall under the umbrella of agent memory often differ substantially in their motivations, implementations, and evaluation protocols, while the proliferation of loosely defined memory terminologies has further obscured conceptual clarity. Traditional taxonomies such as long/short-term memory have proven insufficient to capture the diversity of contemporary agent memory systems. This work aims to provide an up-to-date landscape of current agent memory research. We begin by clearly delineating the scope of agent memory and distinguishing it from related concepts such as LLM memory, retrieval augmented generation (RAG), and context engineering. We then examine agent memory through the unified lenses of forms, functions, and dynamics. From the perspective of forms, we identify three dominant realizations of agent memory, namely token-level, parametric, and latent memory. From the perspective of functions, we propose a finer-grained taxonomy that distinguishes factual, experiential, and working memory. From the perspective of dynamics, we analyze how memory is formed, evolved, and retrieved over time. To support practical development, we compile a comprehensive summary of memory benchmarks and open-source frameworks. Beyond consolidation, we articulate a forward-looking perspective on emerging research frontiers, including memory automation, reinforcement learning integration, multimodal memory, multi-agent memory, and trustworthiness issues. We hope this survey serves not only as a reference for existing work, but also as a conceptual foundation for rethinking memory as a first-class primitive in the design of future agentic intelligence.

cs.CL↗

Control of Electron Energy Distribution Functions by Current Waveform Tailoring in Inductively Coupled Radio Frequency Plasmas

Based on two-dimensional particle-in-cell simulations a novel approach towards Electron Energy Probability Function (EEPF) and plasma chemistry control by Current Waveform Tailoring (CWT) in the coil of inductively coupled discharges is proposed. Varying the shape of this current waveform provides electrical control of the dynamics of the electric field in the plasma. Using sawtooth instead of sinusoidal waveforms allows breaking and controlling the temporal symmetry of the electric field dynamics. In this way CWT allows controlling the EEPF, the ionization-to-excitation rate ratio, and the plasma chemistry.

physics.plasm-ph↗

Large Language Models for Limited Noisy Data: A Gravitational Wave Identification Study

This work investigates whether large language models (LLMs) offer advantages over traditional neural networks for astronomical data processing, in regimes with non-Gaussian, non-stationary noise and limited labeled samples. Gravitational wave observations provide an suitable test case, using only 90 LIGO events, finetuned LLMs achieve 97.4\% accuracy for identifying signals. Further experiments show that, in contrast to traditional networks that rely on large simulated datasets, additional simulated samples do not improve LLM performance, while scaling studies reveal predictable gains with increasing model size and dataset size. These results indicate that LLMs can extract discriminative structure directly from observational data and provide an efficient assessment for gravitational wave identification. The same strategy may extend to other astronomical domains with similar noise properties, such as radio or pulsar observations.

astro-ph.IM↗

ReinFlow: Fine-tuning Flow Matching Policy with Online Reinforcement Learning

We propose ReinFlow, a simple yet effective online reinforcement learning (RL) framework that fine-tunes a family of flow matching policies for continuous robotic control. Derived from rigorous RL theory, ReinFlow injects learnable noise into a flow policy's deterministic path, converting the flow into a discrete-time Markov Process for exact and straightforward likelihood computation. This conversion facilitates exploration and ensures training stability, enabling ReinFlow to fine-tune diverse flow model variants, including Rectified Flow [35] and Shortcut Models [19], particularly at very few or even one denoising step. We benchmark ReinFlow in representative locomotion and manipulation tasks, including long-horizon planning with visual input and sparse reward. The episode reward of Rectified Flow policies obtained an average net growth of 135.36% after fine-tuning in challenging legged locomotion tasks while saving denoising steps and 82.63% of wall time compared to state-of-the-art diffusion RL fine-tuning method DPPO [43]. The success rate of the Shortcut Model policies in state and visual manipulation tasks achieved an average net increase of 40.34% after fine-tuning with ReinFlow at four or even one denoising step, whose performance is comparable to fine-tuned DDIM policies while saving computation time for an average of 23.20%. Project webpage: https://reinflow.github.io/

cs.RO↗

Ramp Josephson junctions of Al/Ti/Sr2RuO4: Observation of single-domain quantum oscillations and the detection of chiral edge current

The determination of how the phase of the superconducting order parameter in a superconductor varies with the spatial direction, which can be done only through the Josephson-effect-based phase-sensitive measurements, is crucial for the establishment of the precise pairing symmetry of the superconductor. So far, such measurements have been done on high-Tc cuprate superconductors but only at a couple of directions for Sr2RuO4 because of the difficulty in preparing Josephson junctions between Sr2RuO4 and an s-wave superconductor with a chosen mutual orientation. Another long-standing issue in Sr2RuO4, which was shown previously to feature a spontaneously broken time-reversal symmetry by muon spin rotation and other measurements, is that the expected presence of chiral surface currents, domains, and domain walls is yet to be explicitly shown experimentally. To address these issues, we have long sought the preparation of high-quality Josephson junctions between Sr2RuO4 and a conventional s-wave with a controllable orientation relative to symmetry axes in Sr2RuO4. We report in this article the successful fabrication of ramp Josephson junctions of Al/Ti/Sr2RuO4 on thin single crystals of Sr2RuO4 obtained by mechanical exfoliation. These junctions were found to show high-quality quantum oscillations consistent with a single-domain Josephson coupling. The normal junction resistance was found to depend extremely sensitively on the supercurrent flowing in the Sr2RuO4 crystal on which the Josephson junction was made. This finding was used in the present work to provide an estimate of the size of the chiral surface current, which is shown to agree with its upper bound established previously.

cond-mat.supr-con↗

A Chromatographic Process Design and Optimization Platform Powered by Large Language Models: A Case Application on Extract of Ginkgo Biloba Leaf

Chromatographic separation technology has been widely applied in pharmaceutical, chemical, and food industries due to its high efficiency. However, traditional human-dependent chromatographic process development faces challenges such as reliance on expert experience, long development cycles, and labor intensity. ChromR, a large language model (LLM)-driven platform for chromatographic process design and optimization, is presented in this work. The platform integrates ChromLLM, a domain-specific LLM trained for chromatography, along with a multi-agent system and an automated chromatographic experimental device. The multi-agent system comprises four agents: domain knowledge answering, experimental design, experimental execution, and data analysis. ChromR enables automatic completion of the entire workflow-including initial process parameter recommendation, experimental design, automated execution, data analysis, and multi-objective optimization. By utilizing ChromR, dependency on expert knowledge is effectively reduced, while labor input and development time are significantly decreased. Chromatographic purification of the extract of Ginkgo biloba leaf (EGBL) was selected as a case study. ChromR successfully developed a chromatographic process within one week that meets multiple objectives, including fraction quality and production efficiency, reducing development time to approximately one-seventh of that required by the conventional paradigm. An intelligent, automated, and universally applicable new paradigm was established for chromatographic process development.

cs.MA↗

GLM-4.5V and GLM-4.1V-Thinking: Towards Versatile Multimodal Reasoning with Scalable Reinforcement Learning

We present GLM-4.1V-Thinking, GLM-4.5V, and GLM-4.6V, a family of vision-language models (VLMs) designed to advance general-purpose multimodal understanding and reasoning. In this report, we share our key findings in the development of the reasoning-centric training framework. We first develop a capable vision foundation model with significant potential through large-scale pre-training, which arguably sets the upper bound for the final performance. We then propose Reinforcement Learning with Curriculum Sampling (RLCS) to unlock the full potential of the model, leading to comprehensive capability enhancement across a diverse range of tasks, including STEM problem solving, video understanding, content recognition, coding, grounding, GUI-based agents, and long document interpretation. In a comprehensive evaluation across 42 public benchmarks, GLM-4.5V achieves state-of-the-art performance on nearly all tasks among open-source models of similar size, and demonstrates competitive or even superior results compared to closed-source models such as Gemini-2.5-Flash on challenging tasks including Coding and GUI Agents. Meanwhile, the smaller GLM-4.1V-9B-Thinking remains highly competitive-achieving superior results to the much larger Qwen2.5-VL-72B on 29 benchmarks. We open-source both GLM-4.1V-9B-Thinking and GLM-4.5V. We further introduce the GLM-4.6V series, open-source multimodal models with native tool use and a 128K context window. A brief overview is available at https://z.ai/blog/glm-4.6v. Code, models and more information are released at https://github.com/zai-org/GLM-V.

cs.CV↗

Benchmark of Segmentation Techniques for Pelvic Fracture in CT and X-ray: Summary of the PENGWIN 2024 Challenge

The segmentation of pelvic fracture fragments in CT and X-ray images is crucial for trauma diagnosis, surgical planning, and intraoperative guidance. However, accurately and efficiently delineating the bone fragments remains a significant challenge due to complex anatomy and imaging limitations. The PENGWIN challenge, organized as a MICCAI 2024 satellite event, aimed to advance automated fracture segmentation by benchmarking state-of-the-art algorithms on these complex tasks. A diverse dataset of 150 CT scans was collected from multiple clinical centers, and a large set of simulated X-ray images was generated using the DeepDRR method. Final submissions from 16 teams worldwide were evaluated under a rigorous multi-metric testing scheme. The top-performing CT algorithm achieved an average fragment-wise intersection over union (IoU) of 0.930, demonstrating satisfactory accuracy. However, in the X-ray task, the best algorithm achieved an IoU of 0.774, which is promising but not yet sufficient for intra-operative decision-making, reflecting the inherent challenges of fragment overlap in projection imaging. Beyond the quantitative evaluation, the challenge revealed methodological diversity in algorithm design. Variations in instance representation, such as primary-secondary classification versus boundary-core separation, led to differing segmentation strategies. Despite promising results, the challenge also exposed inherent uncertainties in fragment definition, particularly in cases of incomplete fractures. These findings suggest that interactive segmentation approaches, integrating human decision-making with task-relevant information, may be essential for improving model reliability and clinical applicability.

eess.IV↗

RLinf: Flexible and Efficient Large-scale Reinforcement Learning via Macro-to-Micro Flow Transformation

Reinforcement learning (RL) has demonstrated immense potential in advancing artificial general intelligence, agentic intelligence, and embodied intelligence. However, the inherent heterogeneity and dynamicity of RL workflows often lead to low hardware utilization and slow training on existing systems. In this paper, we present RLinf, a high-performance RL training system based on our key observation that the major roadblock to efficient RL training lies in system flexibility. To maximize flexibility and efficiency, RLinf is built atop a novel RL system design paradigm called macro-to-micro flow transformation (M2Flow), which automatically breaks down high-level, easy-to-compose RL workflows at both the temporal and spatial dimensions, and recomposes them into optimized execution flows. Supported by RLinf worker's adaptive communication capability, we devise context switching and elastic pipelining to realize M2Flow transformation, and a profiling-guided scheduling policy to generate optimal execution plans. Extensive evaluations on both reasoning RL and embodied RL tasks demonstrate that RLinf consistently outperforms state-of-the-art systems, achieving $1.07\times-2.43\times$ speedup in end-to-end training throughput.

cs.LG↗

Learning Multi-Modal Mobility Dynamics for Generalized Next Location Recommendation

The precise prediction of human mobility has produced significant socioeconomic impacts, such as location recommendations and evacuation suggestions. However, existing methods suffer from limited generalization capability: unimodal approaches are constrained by data sparsity and inherent biases, while multi-modal methods struggle to effectively capture mobility dynamics caused by the semantic gap between static multi-modal representation and spatial-temporal dynamics. Therefore, we leverage multi-modal spatial-temporal knowledge to characterize mobility dynamics for the location recommendation task, dubbed as \textbf{M}ulti-\textbf{M}odal \textbf{Mob}ility (\textbf{M}$^3$\textbf{ob}). First, we construct a unified spatial-temporal relational graph (STRG) for multi-modal representation, by leveraging the functional semantics and spatial-temporal knowledge captured by the large language models (LLMs)-enhanced spatial-temporal knowledge graph (STKG). Second, we design a gating mechanism to fuse spatial-temporal graph representations of different modalities, and propose an STKG-guided cross-modal alignment to inject spatial-temporal dynamic knowledge into the static image modality. Extensive experiments on six public datasets show that our proposed method not only achieves consistent improvements in normal scenarios but also exhibits significant generalization ability in abnormal scenarios.

cs.AI↗

FUSCO: High-Performance Distributed Data Shuffling via Transformation-Communication Fusion

Large-scale Mixture-of-Experts (MoE) models rely on \emph{expert parallelism} for efficient training and inference, which splits experts across devices and necessitates distributed data shuffling to route each token to its assigned experts. However, existing communication libraries handle this shuffling poorly; its overhead can account for over half of end-to-end runtime. We present FUSCO, an MoE-friendly communication library that achieves efficient and lightweight data shuffling through fused data transformation and communication, based on the key observation that MoE's expert-major data layout conflicts with the device-major layout expected by communication operations. FUSCO captures the fine-grained data layout, which is then interpreted by a pipelined communication engine that performs the required shuffling efficiently along the communication path. Lightweight planning and load-balancing mechanisms complement the engine by eliminating redundant communication and dispersing traffic. Evaluations on representative benchmarks illustrate that FUSCO achieves up to 3.84$\times$ and 2.01$\times$ speedups over NCCL and DeepEP (the state-of-the-art MoE communication library), respectively. In end-to-end MoE tasks, compared to NCCL and DeepEP, FUSCO reduces the training latency by 1.17-1.39$\times$ and 1.10-1.19$\times$, and lowers the first-token generation latency in inference by 1.09-1.25$\times$ and 1.06-1.16$\times$.

cs.DC↗