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Yuanyuan Wang

Publications and source records attributed to Yuanyuan Wang.

At least 19 recordsLinked to original sources
arXiv2026

ConvMem: Convolutional Memory for Long-Context Reasoning

While Large Language Models (LLMs) have demonstrated impressive capabilities, they often struggle with extremely long contexts due to fixed context limits. To address this, sequential approaches like MemAgent extend the effective context by reading text in segments and iteratively updating a fixed-size memory. However, this sequential paradigm suffers from high latency and requires costly reinforcement learning (RL) training, which can lead to overfitting on specific datasets. To overcome these limitations, we propose ConvMem, a training-free, highly parallelizable framework that reformulates long-context reasoning as a hierarchical convolution. Inspired by CNNs, ConvMem treats an LLM prompted with a specific query as a convolutional kernel. This kernel summarizes text segments hierarchically, shortening the reasoning path from a linear chain into a logarithmic tree. Specifically, ConvMem integrates \textit{Configurable Strides} and \textit{Skip Connections} to ensure robust evidence capture and propagation, while employing \textit{Multi-Kernel Convolution} to decompose complex queries into disentangled semantic channels. This design not only mitigates error accumulation but also enables massive parallelization across both text segments and reasoning threads. Experiments on RULER-HotpotQA and RULER-2WikiMultiHopQA demonstrate that ConvMem outperforms training-free baselines and avoids the risk of overfitting to parametric priors often observed in RL-trained models on out-of-distribution tasks.

cs.AI↗
arXiv2026

mRNA Design and Optimization with Deep Knowledge-Infused Approach

The mRNA optimization is essential for mRNA vaccines, therapies, and industrial protein production. Based on current explorations, an ideal optimization approach should simultaneously (i) prevent unintended amino-acid changes, (ii) optimize multiple, biologically relevant objectives, and (iii) retain computational efficiency. However, existing methods are forced to trade off between these perspectives, forming an "impossible triangle." We present RNop, a knowledge-infused Transformer that integrates mechanism-aligned losses to address this problem. By encoding biological prior knowledge in losses, RNop makes knowledge infusion explicit and controllable across optimization focus. Trained on over 6 million sequences, in silico analyses show RNop resolves the "impossible triangle" of mRNA optimization with absolute sequence fidelity, significantly improved biological metrics, and high throughput. In in vitro validation, it can deliver up to 2.28-fold expression gain. Ablation studies reveal how each prior contributes to targeted improvements, yielding mechanism-level interpretability. RNop represents a shift in mRNA optimization methodology: by infusing explicit and interpretable knowledge, the "black-box" mRNA design can be transformed into a predictable, explainable engineering problem. RNop is designed as an extensible platform: additional biological priors can be incorporated as modular, mechanism-aligned loss functions, enabling future development and adaptation to related sequence design problems.

q-bio.QM↗
arXiv2026

CARD: Calibration via Agreement in Reverse Diffusion for Out-of-Domain MRI Segmentation

Probability calibration aligns model confidence with predictive accuracy, enabling clinicians to identify unreliable segmentation regions. This alignment breaks down under domain shift, where artifacts and unseen protocols produce confident errors. Existing post-hoc methods adapt the correction at test time, conditioning on predictive entropy, the logit pattern, or augmentation response, but each proxy is read from the terminal prediction, the very quantity that shift corrupts. This motivates reliability evidence beyond the terminal prediction, which categorical diffusion provides in two ways. First, a generative shape prior keeps a capacity-limited reference intact when appearance is corrupted, so its disagreement with the primary segmentor highlights primary-model errors. Second, every reverse step yields a class distribution, separating persistent disagreement from transient discrepancy. Aggregated over the trajectory, this disagreement correlates with Dice at 0.788, against 0.521 for a matched discriminative control. We therefore propose CARD (Calibration via Agreement in Reverse Diffusion), which maps the temporal aggregate of this disagreement to a temperature field applied per pixel across all classes, so that confidence changes while the segmentation does not. Across cardiac, prostate and brain MRI shifts, CARD lowers calibration error in 45 of 49 comparisons against the strongest baseline in each setting.

cs.CV↗
arXiv2026

Physics from Video: Identifiability of Time-Invariant Second-Order ODEs under Minimal Trajectory Conditions

Bridging the gap between visual realism and physical understanding is a core challenge for video-based world models. We study the structural identifiability of continuous-time physical laws from raw pixels, focusing on whether an encoder-only pipeline can uniquely recover the parameters of second-order linear ODEs. We prove that a level-set slope-coverage condition ensures the learned latent space is locally affine to the true physical state, enabling exact parameter recovery. Our theory provides the first characterization of minimal data requirements across damping regimes, establishing that underdamped systems are identifiable from a single video clip, whereas other regimes require three diverse trajectories. We further introduce a variance-floor regularizer to stabilize the decoder-free objective and prevent latent collapse. Validated on synthetic and real-world data, our approach demonstrates that interpretable physical constants can be reliably estimated from video without the need for compute-intensive pixel reconstruction, ensuring both physical correctness and transparency. Code is available at https://github.com/wenjiewang3/PhysicsFromVideo.

cs.CV↗
arXiv2026

HeartMuLa: A Family of Open Sourced Music Foundation Models

We present a family of open-source Music Foundation Models designed to advance large-scale music understanding and generation across diverse tasks and modalities. Our framework consists of four major components: (1) HeartCLAP, an audio-text alignment model; (2) HeartTranscriptor, a robust lyric recognition model optimized for real-world music scenarios; and (3) HeartCodec, a low-frame-rate (12.5 Hz) yet high-fidelity music codec tokenizer that captures long-range musical structure while preserving fine-grained acoustic details and enabling efficient autoregressive modeling; (4) HeartMuLa, an LLM-based song generation model capable of synthesizing high-fidelity music under rich, user-controllable conditions (e.g., textual style descriptions, lyrics, and reference audio). In addition, it provides two specialized modes: (i) fine-grained musical attribute control, which allows users to specify the style of different song sections (e.g., intro, verse, chorus) using natural language prompts; and (ii) short, engaging music generation, which is suitable as background music for short videos. Lastly, HeartMuLa improves significantly when scaled to 7B parameters. For the first time, we show that a Suno-level, commercial-grade system can be reproduced using academic-scale data and GPU resources. We expect these foundation models to serve as strong baselines for future research and to facilitate practical applications in multimodal content production.

cs.SD↗
arXiv2026

CIPHER: Causal Intervention Pathways for Healthcare Equity and Robustness

Deep learning models for medical diagnosis frequently exhibit substantial performance disparities across sensitive subgroups (e.g., race, sex), even when average accuracy is high. While generative data augmentation offers a route to mitigate this, existing strategies are suboptimal; they typically address only one or two dependency channels between sensitive attributes and image features. We formalize the medical image formation process via a structural causal model, revealing that sensitive attributes actually influence image content through four distinct pathways-a structural complexity neglected by prior works. Based on this insight, we introduce CIPHER (Causal Intervention Pathways for Healthcare Equity and Robustness), a framework designed to systematically intervene on all four causal paths. To achieve this, CIPHER utilizes a diffusion backbone equipped with classifier-free guidance and null-text inversion. This technical design enables the faithful reconstruction of patient-specific anatomy while allowing for the precise, editable synthesis of counterfactuals required to break sensitive dependency chains. We tested CIPHER using chest X-ray and dermoscopy benchmarks across both standard and shifted data distributions. By employing a multi-pathway intervention strategy, our model reduced worst-group disparities by an average of 35.8% compared to disease-conditioned synthesis baselines, while also improving total diagnostic accuracy

cs.CV↗
arXiv2026

Disentangling Continuous-Time Latent Dynamics: Identifiability of Latent SDEs via Diffusion Shifts

Causal representation learning for time series has developed strong identifiability results in discrete-time latent causal models, but identifiability in continuous-time latent stochastic differential equation (SDE) models remains largely open. We address this gap using environment-induced shifts in diffusion covariance. We study additive-noise latent SDEs observed through an unknown nonlinear diffeomorphism, with shared drift but environment-specific diffusion covariance. We show that two diagonal diffusion regimes with pairwise distinct coordinate-wise variance ratios identify the latent coordinates up to permutation and scaling, without any sparsity assumption on the drift. We first prove this result for linear Ornstein--Uhlenbeck systems and then extend it to general additive-noise latent SDEs. Under mild smoothness, the instantaneous drift-Jacobian causal graph is identifiable up to the same permutation. We propose a two-stage estimator for latent disentanglement and optional graph recovery; experiments on synthetic systems confirm the predicted identifiability boundary, and an application to Hardanger Bridge monitoring data illustrates the approach on real sensor trajectories.

cs.LG↗
arXiv2026

Enhancing Brain MRI Anomaly Detection and Reasoning with ROI Rethink and Synthetic Data

Medical vision-language models typically generate diagnoses through single-pass inference without indicating which image regions support their conclusions. This lack of spatial grounding limits clinical utility: outputs cannot be audited, and models may hallucinate findings on normal scans. We present BrReMark (Brain Rethink via ROI Marking), a framework that introduces explicit region marking into brain MRI diagnosis. The model first generates hypotheses about potential abnormalities and grounds them through explicit bounding box marking, then verifies conclusions by re-examining the marked evidence. Training combines supervised fine-tuning on structured reasoning trajectories with reinforcement learning using a composite reward over localization accuracy and diagnostic reasoning. Furthermore, we integrate a domain randomization-based pathology synthesis augmentation strategy to improve the model's generalizability to out-of-distribution (OOD) data. On internal benchmark, BrReMark improves mAP50 from 0.74% to 37.54% compared to the base model, while achieving 21.57% Clinical F1 and 45.26% diagnostic accuracy. On NOVA OOD benchmark, it also achieves competitive overall performance with a 45.7% reduction in false positives compared to the state-of-the-art, indicating reduced hallucination on rare pathologies. These findings suggest that explicit hypothesis-verification grounding is a practical path toward trustworthy open-ended brain MRI diagnosis across both in-distribution and OOD settings.

cs.CV↗
arXiv2026

AnisoLift: Anisotropic Latent Representations for Coarse Particle Liquid Enhancement

Particle-based liquid simulation is widely used in graphics and physical modeling, but high-resolution rollouts remain computationally expensive. Consequently, many methods aim to recover fine-scale dynamics and dense transport patterns from coarse particle simulations. However, these methods typically rely on additional particle generation, which still incurs considerable computational overhead and leads to poor representation. To this end, we propose AnisoLift, a structured latent closure framework that augments each coarse particle with learnable anisotropic ellipsoidal components. This allows the model to capture directional local structure from the underlying high-resolution flow without introducing extra particles. Given a coarse simulation, our model predicts residual corrections to particle states to bring the updated state closer to the aligned high-resolution teacher. Our training objective jointly supervises particle dynamics and anisotropic geometric structure, encouraging both physical consistency and structural coherence. Extensive experiments show that our approach enhances coarse liquid simulations through improving fidelity to fully resolved flow behavior.

cs.GR↗
arXiv2026

Causal Ensemble Agent: Hierarchical Causal Discovery with LLM-guided Expert Reweighting

Causal discovery aims to uncover causal structures from observational data, which is crucial for real-world decision-making. However, different causal discovery algorithms can produce divergent results that conflict with each other, complicating the identification of accurate causal graphs. Traditional approaches rely on numerical values and statistical assumptions, often ignoring rich domain-specific information, such as feature descriptions, which could also help structure learning. While recent works explore using Large Language Models (LLMs) to infer causal relations via direct queries, such methods can be unreliable due to a lack of alignment with the actual data. To address these limitations, we propose Causal Ensemble Agent (CEA), a novel framework that aggregates structural insights from statistical discovery experts across different graph levels via linear opinion pooling, and uses an LLM as a meta-referee to dynamically reweight experts when the aggregated confidence is close to the decision boundary, thereby composing an improved and more complete causal graph. Extensive experiments on both synthetic and real-world datasets demonstrate that CEA achieves the strongest overall performance across a wide range of causal discovery methods, highlighting the effectiveness of using LLMs for meta-analysis in causal discovery.

cs.LG↗
arXiv2026

UniSRM: A Unified Speech Reward Model for Reasoning-Based Fine-grained Assessment

Evaluating speech generation still relies heavily on human judgments, such as Mean Opinion Score (MOS), which are expensive, subjective, and difficult to reproduce at scale. While a few recent studies have begun to explore AudioLLM-based judge models, existing efforts typically target only a narrow set of scenarios (e.g., utterance-level quality or single-turn dialogue) and provide limited coverage of diverse speech generation tasks and evaluation dimensions. In this work, we propose UniSRM, a unified speech reward model that can support multi-dimensional, interpretable reward signals with reliable reasoning. To support training and evaluation, we introduce UniSRM-Data and UniSRM-Bench, covering speech evaluation tasks from utterance-level quality to context-level coherence. Based on this dataset, we present the unified speech reward model, UniSRM, with a two-stage pipeline that enables reasoning-based fine-grained assessment. Furthermore, we introduce Reasoning-Consistent Rewards to improve the reliability of the reasoning process. Experiments show that UniSRM delivers more reliable and human-aligned judgments across a broad range of speech evaluation tasks, offering a practical foundation for scalable and unified evaluation of speech quality.

eess.AS↗
arXiv2026

Defining Robust Ultrasound Quality Metrics via an Ultrasound Foundation Model

Clinicians lack a principled framework to quantify diagnostic utility in ultrasound reconstructions. Existing standards like PSNR and VGG-LPIPS are inadequate, failing to account for modality-specific physics or the structural nuances of acoustic imaging. We close this gap with a TinyUSFM-based evaluation framework featuring two distinct metrics: TinyUSFM-uLPIPS, a full-reference perceptual distance based on multi-layer token relations, and TinyUSFM-NRQ, a deployable no-reference quality score utilizing clean-manifold modeling and worst-region aggregation to detect localized harmful artifacts. We demonstrate that the presented metrics have four unique advantages: 1) Task-linked quality, where TinyUSFM-uLPIPS achieves superior calibration with semantic task damage, accurately reflecting Dice-score drops in segmentation where VGG-based metrics fail; 2) Cross-organ comparability, maintaining stable scoring scales and consistent severity rankings across diverse anatomical sites and domain-shifted data; 3) PSNR-consistent sensitivity, with TinyUSFM-NRQ providing a reliable quality score without ground-truth images that remains consistent with traditional fidelity benchmarks (i.e. PSNR); and 4) Clinical utility, improving the prediction of expert preference from 47.2$\%$ to 72.8$\%$ accuracy and producing super-resolution reconstructions preferred by sonographers. By integrating these advantages into a unified assessment and optimization loop, this work establishes a modality-aligned standard that finally bridges the gap between algorithmic performance and diagnostic utility. Our code is available at https://github.com/sextant-fable/US-Metrics.

eess.IV↗
arXiv2026

WGAN based Inverse Design of Active Dual Band FSS with Switchable Transmission

This letter presents a novel design method for switchable dual band transmissive frequency selective surface (FSS). The proposed FSS possesses characteristics of maintaining passband characteristics at high frequencies, while switching from transmission to reflection at low frequencies with pin diodes states altering. Specifically, we propose a crystal growth-based topology generation strategy, and utilize a simplified U-Net Wasserstein GAN (WGAN) neural network model to establish an inverse mapping model from electromagnetic response to structure topology parameters. The trained WGAN achieves training and validation accuracies of 95.59% and 90.84%, while the simplified U-Net attains training and validation accuracies of 98.5% and 94.1%. Using the trained WGAN. The generated structural topologies were validated through full-wave simulations and experimental measurements. The proposed method enhances the design flexibility and overcomes the time- consuming drawbacks of conventional FSS design.

physics.app-ph↗
arXiv2026

Analysis and Design of Double-Transmitting Coil Systems based on Parity-Time Symmetry

The wireless power transfer (WPT) system based on parity-time (PT) symmetry has the advantages of robustness, stability, and efficient power transmission. However, traditional PT symmetry structures have limited voltage power output and are susceptible to horizontal misalignment effects. Multiple transmission coils have been proven to improve the power and misalignment tolerance of WPT systems, but variations in inter-coil coupling significantly affect transmission power. Towards this end, this article proposes a double-transmitting coil WPT system based on PT symmetry, which is innovative in that a novel negative resistance structure based on operational amplifier (OA) is proposed, and the parallel structure of double-transmitting coil is applied to this negative resistance structure. Compared with the traditional WPT system based on a single-transmitting coil PT, this system improves the power and misalignment tolerance in the PT symmetry region. The large-sized and small-sized receiving coils increase the load power to 313% and 185% respectively. Moreover, in the symmetry region, the displacement of the receiving coil in the horizontal and vertical directions results in variations of the equivalent coupling coefficient, which can achieve stable power transmission in three dimensions. The voltage fluctuation rate of both receiving coils does not exceed 3.4%, greatly improving the degree of freedom of the receiving system.

physics.app-ph↗
arXiv2026

DepthPilot: From Controllability to Interpretability in Colonoscopy Video Generation

Controllable medical video generation has achieved remarkable progress, but it still lacks interpretability, which requires the alignment of generated contents with physical priors and faithful clinical manifestations. To push the boundaries from mere controllability to interpretability, we propose DepthPilot, the first interpretable framework for colonoscopy video generation. This work takes a step toward trustworthy generation through two synergistic paradigms. To achieve explicit geometric grounding, DepthPilot devises a prior distribution alignment strategy, injecting depth constraints into the diffusion backbone via parameter-efficient fine-tuning to ensure anatomical fidelity. To enhance intrinsic nonlinear modeling under these geometric constraints, DepthPilot employs an adaptive spline denoising module, replacing fixed linear weights with learnable spline functions to capture complex spatio-temporal dynamics. Extensive evaluations across three public datasets and in-house clinical data confirm DepthPilot's robust ability to produce physically consistent videos. It achieves FID scores below 15 across all benchmarks and ranks first in clinician assessments, bridging the gap between "visually realistic" and "clinically interpretable". Moreover, DepthPilot-generated videos are expected to enable reliable 3D reconstruction, facilitating surgical navigation and blind region identification, and serve as a foundation toward the colorectal world model.

cs.CV↗
arXiv2026

Unified Ultrasound Intelligence Toward an End-to-End Agentic System

Clinical ultrasound analysis demands models that generalize across heterogeneous organs, views, and devices, while supporting interpretable workflow-level analysis. Existing methods often rely on task-wise adaptation, and joint learning may be unstable due to cross-task interference, making it hard to deliver workflow-level outputs in practice. To address these challenges, we present USTri, a tri-stage ultrasound intelligence pipeline for unified multi-organ, multi-task analysis. Stage I trains a universal generalist USGen on different domains to learn broad, transferable priors that are robust to device and protocol variability. To better handle domain shifts and reach task-aligned performance while preserving ultrasound shared knowledge, Stage II builds USpec by keeping USGen frozen and finetuning dataset-specific heads. Stage III introduces USAgent, which mimics clinician workflows by orchestrating USpec specialists for multi-step inference and deterministic structured reports. On the FMC\_UIA validation set, our model achieves the best overall performance across 4 task types and 27 datasets, outperforming state-of-the-art methods. Moreover, qualitative results show that USAgent produces clinically structured reports with high accuracy and interpretability. Our study suggests a scalable path to ultrasound intelligence that generalizes across heterogeneous ultrasound tasks and supports consistent end-to-end clinical workflows. The code is publicly available at: https://github.com/MacDunno/USTri.

cs.CV↗
arXiv2026

EchoAgent: Towards Reliable Echocardiography Interpretation with "Eyes","Hands" and "Minds"

Reliable interpretation of echocardiography (Echo) is crucial for assessing cardiac function, which demands clinicians to synchronously orchestrate multiple capabilities, including visual observation (eyes), manual measurement (hands), and expert knowledge learning and reasoning (minds). While current task-specific deep-learning approaches and multimodal large language models have demonstrated promise in assisting Echo analysis through automated segmentation or reasoning, they remain focused on restricted skills, i.e., eyes-hands or eyes-minds, thereby limiting clinical reliability and utility. To address these issues, we propose EchoAgent, an agentic system tailored for end-to-end Echo interpretation, which achieves a fully coordinated eyes-hands-minds workflow that learns, observes, operates, and reasons like a cardiac sonographer. First, we introduce an expertise-driven cognition engine where our agent can automatically assimilate credible Echo guidelines into a structured knowledge base, thus constructing an Echo-customized mind. Second, we devise a hierarchical collaboration toolkit to endow EchoAgent with eyes-hands, which can automatically parse Echo video streams, identify cardiac views, perform anatomical segmentation, and quantitative measurement. Third, we integrate the perceived multimodal evidence with the exclusive knowledge base into an orchestrated reasoning hub to conduct explainable inferences. We evaluate EchoAgent on CAMUS and MIMIC-EchoQA datasets, which cover 48 distinct echocardiographic views spanning 14 cardiac anatomical regions. Experimental results show that EchoAgent achieves optimal performance across diverse structure analyses, yielding overall accuracy of up to 80.00%. Importantly, EchoAgent empowers a single system with abilities to learn, observe, operate and reason like an echocardiologist, which holds great promise for reliable Echo interpretation.

cs.CV↗
arXiv2026

TinyUSFM: Towards Compact and Efficient Ultrasound Foundation Models

Foundation models for medical imaging demonstrate superior generalization capabilities across diverse anatomical structures and clinical applications. Their outstanding performance relies on substantial computational resources, limiting deployment in resource-constrained clinical environments. This paper presents TinyUSFM, the first lightweight ultrasound foundation model that maintains superior organ versatility and task adaptability of our large-scale Ultrasound Foundation Model (USFM) through knowledge distillation with strategically curated small datasets, delivering significant computational efficiency without sacrificing performance. Considering the limited capacity and representation ability of lightweight models, we propose a feature-gradient driven coreset selection strategy to curate high-quality compact training data, avoiding training degradation from low-quality redundant images. To preserve the essential spatial and frequency domain characteristics during knowledge transfer, we develop domain-separated masked image modeling assisted consistency-driven dynamic distillation. This novel framework adaptively transfers knowledge from large foundation models by leveraging teacher model consistency across different domain masks, specifically tailored for ultrasound interpretation. For evaluation, we establish the UniUS-Bench, the largest publicly available ultrasound benchmark comprising 8 classification and 10 segmentation datasets across 15 organs. Using only 200K images in distillation, TinyUSFM matches USFM's performance with just 6.36% of parameters and 6.40% of GFLOPs. TinyUSFM significantly outperforms the vanilla model by 9.45% in classification and 7.72% in segmentation, surpassing all state-of-the-art lightweight models, and achieving 84.91% average classification accuracy and 85.78% average segmentation Dice score across diverse medical devices and centers.

eess.IV↗