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Yubing Han

Publications and source records attributed to Yubing Han.

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Electro-Optic Active Metasurfaces for High-Speed Photonic Applications

Metasurfaces are artificially engineered ultrathin nanostructured surfaces, capable of flexibly manipulating light-matter interactions on compact platforms, and thereby of great significance for a wide range of applications within modern optics and photonics, including communications, computing, sensing, and quantum technologies. However, the inherently static nature of conventional metasurfaces severely limits their functionalities and thus range of possible applications. Benefiting from integration of the metasurface platform for shaping optical wavefronts with ultrafast electro-optic (EO) materials, active EO metasurfaces have emerged as a frontier research direction targeting advanced photonic devices. This paper systematically reviews the latest progress in this field, featuring a comprehensive comparison of performances and application scenarios of mainstream EO materials such as lithium niobate, barium titanate and organic EO polymers. Modulation mechanisms based on the Pockels and Kerr effects along with the corresponding active metasurface implementations are summarized. Furthermore, improvements in modulation efficiency enabled by advantageously exploiting resonant structural designs and associated phenomena, including Fabry-Perot resonances, Mie resonances, surface plasmon polaritons, quasi-bound states in the continuum, surface lattice resonances, and guided-mode resonances, are presented and summerized in detail. Current challenges related to metasurface design, nanofabrication, performance and heterogeneous integration are also discussed. Finally, future research directions are outlined, highlighting interdisciplinary developments, novel material engineering, and AI-assisted design as key pathways to enable practical use of active EO metasurfaces in modern optics and photonics, including quantum information technologies.

physics.optics

Large-Aperture All-Solid-State Cascaded Liquid-Crystal Beam Steering for High-Resolution Wide-Field Imaging

High-resolution wide-field imaging is essential for applications requiring simultaneous global coverage and local detail, yet conventional approaches face a fundamental trade-off: wide-FOV cameras sacrifice spatial sampling density by distributing finite detector pixels over a broad angular range, while telephoto systems resolve fine features at the cost of scene coverage. Beam-steering devices can mitigate this trade-off but are currently limited in achieving simultaneously all-solid-state, large aperture, and high-speed operation. Here, we report an all-solid-state large-aperture cascaded liquid-crystal beam-steering (CaLiBS) imaging system that extends the effective angular range of a high-resolution narrow-FOV camera by electrically steering sub-FOVs. The CaLiBS module comprises cascaded liquid crystal waveplates and liquid crystal Pancharatnam-Berry phase gratings; a theoretical voltage-prediction model with a hierarchical search algorithm enables efficient calibration under oblique incidence and 10 times faster calibration speed compared with conventional methods. The calibrated system addresses sub-FOVs across 30.3{\deg} * 30.3{\deg} at 2{\deg} intervals with diffraction efficiency above 60%. Sequential sub-FOV acquisition reconstructs a 34.7 * 34.7 composite image, an 8.6-fold enhancement in spatial-bandwidth product over a single-shot wide-FOV camera using the same detector. Combined with object tracking methods, sub-FOV switching further enables high-resolution tracking of moving vehicles within the wide-area scene. This cascaded LC architecture offers a scalable pathway toward compact, vibration-free, and high-resolution wide-field observation.

physics.optics

Beyond Autophagy: VPS39 Deficiency Triggers Migrasome-Driven Stress Adaptation Revealed by Super-Resolution Imaging

Autophagy and migrasome formation constitute critical cellular mechanisms for maintaining cellular homeostasis, however, their potential compensatory interplay remains poorly understood. In this study, we identify VPS39, a core component of the HOPS complex, as a molecular switch coordinating these processes. Genetic ablation of VPS39 not only impairs autophagic flux but also triggers cell migration through RhoA/Rac1 GTPases upregulation, consequently facilitating migrasome formation. Using super-resolution microscopy, we further demonstrate that migrasomes serve as an alternative disposal route for damaged mitochondria during VPS39-induced autophagy impairment, revealing a novel stress adaptation mechanism. Our work establishes a previously unrecognized autophagy-migrasome axis and provides direct visual evidence of organelle quality control via migrasomal extrusion. These findings position VPS39-regulated pathway switching as a potential therapeutic strategy for neurodegenerative diseases characterized by autophagy dysfunction.

q-bio.CB

SMILE: a universal tool for modulated-enhanced localization microscopy to achieve minimal three-dimensional resolution

Modulation-enhanced localization microscopy (MELM) has demonstrated significant improvements in both lateral and axial localization precision compared to conventional single-molecule localization microscopy (SMLM). However, lateral modulated illumination based MELM (MELMxy) remains fundamentally limited to two-dimensional imaging. Here we present three-dimensional Single-Molecule Modulated Illumination Localization Estimator (SMILE) that synergistically integrates lateral illumination modulation with point spread function engineering. By simultaneously exploiting lateral modulation patterns and an accurate point spread function (PSF) model for 3D localization, SMILE achieves near-theoretical-minimum localization uncertainty, demonstrating an average 4-fold enhancement in lateral precision compared to conventional 3D-SMLM. Crucially, SMILE exhibits exceptional compatibility with diverse PSFs and different illumination patterns with various structures including 4Pi configurations, making it a versatile tool that can be easily adapted for different experimental setups. When integrated with 4Pi microscopy, 4Pi-SMILE shows particular promise for achieving sub-10 nm axial resolution and approaching isotropic resolution. From the simulations and proof-of-concept experiments, we verified the superiority of SMILE over 3D-SMLM and ordinary MELM. We highlight SMILE as a novel methodology and robust framework that holds great potential to significantly promote the development of MELM.

physics.optics

In situ fully vectorial tomography and pupil function retrieval of tightly focused fields

Tightly focused optical fields are essential in nano-optics, but their applications have been limited by the challenges of accurate yet efficient characterization. In this article, we develop an in situ method for reconstructing the fully vectorial information of tightly focused fields in three-dimensional (3D) space, while simultaneously retrieving the pupil functions. Our approach encodes these fields using phase-modulated focusing and polarization-split detection, followed by decoding through an algorithm based on least-sampling matrix-based Fourier transform and analytically derived gradient. We further employ a focus scanning strategy. When combined with our decoding algorithm, this strategy mitigates the imperfections in the detection path. This approach requires only 10 frames of 2D measurements to realize approximate 90% accuracy in tomography and pupil function retrieval within 10s. Thus, it serves as a robust and convenient tool for the precise characterization and optimization of light at the nanoscale. We apply this technique to fully vectorial field manipulation, adaptive-optics-assisted nanoscopy, and addressing mixed-state problems.

physics.optics

Far-field Super-resolution Chemical Microscopy

Far-field chemical microscopy providing molecular electronic or vibrational fingerprint information opens a new window for the study of three-dimensional biological, material, and chemical systems. Chemical microscopy provides a nondestructive way of chemical identification without exterior labels. However, the diffraction limit of optics hindered it from discovering more details under the resolution limit. Recent development of super-resolution techniques gives enlightenment to open this door behind far-field chemical microscopy. Here, we review recent advances that have pushed the boundary of far-field chemical microscopy in terms of spatial resolution. We further highlight applications in biomedical research, material characterization, environmental study, cultural heritage conservation, and integrated chip inspection.

physics.optics

Scalable universal tunable virtual-wavevector spatial frequency shift (TVSFS) super-resolution imaging

Developing a chip-based super-resolution imaging technique with large field-of-view (FOV), deep subwavelength resolution, and compatibility for both fluorescent and non-fluorescent samples is desired for material science, biomedicine, and life researches, etc. Previous on-chip super-resolution methods focus on either fluorescent or non-fluorescent imaging, putting an urgent requirement on the general imaging technique compatible with both of them. Here, we introduce a universal super-resolution imaging method based on tunable virtual-wavevector spatial frequency shift (TVSFS), realizing both labeled and label-free super-resolution imaging on a single delicately fabricated scalable photonic chip. Theoretically, with TVSFS, the diffraction limit of a linear optical system can be overcome, and the resolution can be improved more than three times, which is the limitation for most super-resolution imaging based on spatial frequency engineering. Diffractive units were fabricated on the chip's surface to provide a wavevector-variable evanescent wave illumination and induce tunable deep SFS in the samples' Fourier space. A resolution of {\lambda}/4.7 for the label-free sample and {\lambda}/7.1 for the labeled sample with a large FOV could be achieved with a CMOS-compatible process on a GaP chip. The large FOV, high-compatibility, and high-integration TVSFS chip may advance the fields like cell engineering, precision inspection in the industry, chemical research, etc.

physics.optics

Deep-Learned Broadband Encoding Stochastic Filters for Computational Spectroscopic Instruments

Computational spectroscopic instruments with Broadband Encoding Stochastic (BEST) filters allow the reconstruction of the spectrum at high precision with only a few filters. However, conventional design manners of BEST filters are often heuristic and may fail to fully explore the encoding potential of BEST filters. The Parameter Constrained Spectral Encoder and Decoder (PCSED) - a neural network-based framework is presented for the design of BEST filters in spectroscopic instruments. By incorporating the target spectral response definition and the optical design procedures comprehensively, PCSED links the mathematical optimum and practical limits confined by available fabrication techniques. Benefiting from this, the BEST-filter-based spectral camera present a higher reconstruction accuracy with up to 30 times' enhancement and a better tolerance on fabrication errors. The generalizability of PCSED is validated in designing metasurface- and interference-thin-film-based BEST filters.

physics.ins-det