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Yuhao Huang

Publications and source records attributed to Yuhao Huang.

At least 19 recordsLinked to original sources

Cross-Modal Ultrasound-MRI Learning for Fetal Brain Ventricular Volumetry and Abnormality Screening

Assessment of ventriculomegaly (VM) on fetal brain ultrasound relies primarily on measuring lateral ventricular atrial width on standard planes, which is operator-dependent and may not fully reflect the overall ventricular enlargement. Fetal brain MRI provides more reliable volumetric information but is costly and less accessible for routine use. To address these limitations, we propose VIFBA, an ultrasound video-based framework for fetal brain assessment that predicts MRI-derived lateral ventricular volume, classifies VM severity, and identifies potential non-VM fetal brain abnormalities. Our contribution is three-fold. First, we introduce a joint-embedding predictive architecture (JEPA)-inspired tube latent prediction objective that leverages spatio-temporal coherence in ultrasound videos to enhance representation learning. Second, we develop a contrastive cross-modal alignment strategy that transfers structural information from MRI to ultrasound during training, while requiring ultrasound alone at inference. Third, we augment VIFBA with a training-free vision-language model and retrieval augmentation to verify uncertain predictions and identify potential non-VM fetal brain abnormalities. We validated VIFBA on a large dataset comprising 857 cases (3,196 videos) with paired fetal brain ultrasound and MRI examinations. On held-out test data, VIFBA achieved an MAE of 0.5909 mL and Pearson correlation coefficient of 0.9907 for ventricular volume regression, 0.9400 accuracy for VM severity classification, and an F1 score of 0.7764 for multi-abnormality classification, substantially outperforming single-task baselines, video-based strong competitors, and state-of-the-art foundation models. By enabling MRI-informed volumetric assessment from routine ultrasound alone, VIFBA offers a practical and potentially broadly deployable pathway toward accurate and affordable prenatal brain screening.

eess.IV

Rethinking Medical Landmark Localization with Prototype Learning-based Progressive Offset Correction

Accurate landmark localization in medical images is a fundamental step for quantitative clinical measurement and downstream analysis. Existing localization methods have advanced, among which multi-stage refinement is a superior solution. Although this strategy mitigates the anatomical ambiguity inherent in single-stage global predictions, its high computational cost limits practical applicability. In this work, we propose a parameter-economic model, PPOC-LL, which leverages Prototype learning-based Progressive Offset Correction for Landmark Localization. Our contribution is three-fold. First, to drive coarse-to-fine landmark optimization, we introduce a multi-scale dynamic perception strategy for patch-level feature pyramid modeling. Second, to effectively handle anatomically similar patterns, we design a similarity-driven prototype learning mechanism that captures informative local semantics for robust offset prediction. Last, to stabilize the model learning and improve the overall performance, we incorporate a novel error-aware reliability regularization via tolerance-based balancing. We collected a large validation cohort, including two public and one private datasets spanning X-ray and ultrasound modalities, covering cephalometric, symphysis-fetal head, and fetal heart landmarks. Extensive experiments demonstrate that PPOC-LL achieves satisfactory performance with a favorable trade-off between accuracy and model complexity.

cs.CV

Second Order Drifting Models

Drifting models are a recent class of one-step generative models that evolve the model distribution during training using a predefined sample-based drift field. Although they avoid iterative inference, their kernel-based drift fields induce frequency-dependent training dynamics: In the linearized regime, each Fourier mode of the density residual decays at a rate determined by the kernel spectrum, leading to slow recovery of fine-scale structure. We propose Second-Order Drifting Models, which lift drifting dynamics into phase space by augmenting generated samples with artificial velocity variables. We show that the resulting density perturbations obey accelerated second-order dynamics in Fourier space, connecting drifting models to the celebrated Nesterov acceleration from optimization theory. This provides a principled mechanism for mitigating the spectral stiffness of first-order drifting while preserving one-step inference. We derive a practical semi-implicit training algorithm and evaluate it on synthetic distribution matching, sequential data generation, and robotic control. Across these settings, the second-order drifting model improves convergence behavior and achieves competitive or superior performance over first-order drifting baselines.

cs.LG

Recurrent Contrastive Learning for Imbalanced Medical Image Classification

Medical image classification often suffers from class imbalance due to the inherent disparities in disease incidence. Existing approaches, such as class resampling and loss reweighting, mainly improve learning within the observed feature distribution, but do not explicitly enlarge the latent support region of tail classes. As a result, tail-class representations remain overly compact and are easily encroached upon by head classes, leading to biased decision boundaries. In this work, we propose Recurrent Contrastive Learning (RCL) for imbalanced medical image classification. RCL progressively expands the support region of tail classes by recurrently reusing historical feature states across training phases. Specifically, we adopt DINOv3 with LoRA adapters as the backbone to provide robust feature embeddings. We then devise a Temporal Memory Queue (TMQ) to preserve corpus-level features across training phases and provide diversified global references for contrastive learning. Based on TMQ, we construct Temporal Anchors (TARs) to form an anchor field around tail classes. This field enlarges the support region of tail classes, suppresses head-class encroachment, and improves inter-class separation. Extensive experiments on three imbalanced medical datasets demonstrate that RCL achieves consistent improvements over strong baselines. The code is available at https://github.com/dndins/RCL.

cs.CV

Prototype Memory-Guided Training-Free Anomaly Classification and Localization in Prenatal Ultrasound

Prenatal anomaly classification and localization is of critical importance for fetal health and pregnancy management. Although ultrasound (US) is the primary modality for prenatal screening, accurate diagnosis remains challenging due to the low prevalence and high heterogeneity of anomalies. Existing deep learning methods for prenatal tasks rely on large-scale annotated datasets, which are difficult to obtain in practice. Although few-shot learning alleviates data scarcity, it typically requires fine-tuning for new categories, limiting its practicality in resource-limited clinical settings. To address these challenges, we propose a training-free framework for multi-class prenatal US anomaly classification and localization that operates with only a few reference images per class, representing the first exploration of this setting. Our framework comprises three key components: (1) a memory bank with multi-granular prototypes that explicitly models both class-level semantics and anomaly characteristics; (2) a prototype-driven soft merging mechanism that aggregates discriminative features to detect the anomaly region; and (3) a class-aware refinement strategy that leverages prototype consistency to improve category prediction. Extensively validated on a multi-center prenatal US dataset containing 1,149 cases, with a total of 2,357 images and 9 categories, our proposed method outperforms the competitors.

cs.CV

Foundation Model-driven Key Anatomy Frame Selection for Blind-sweep Ultrasound Fetal Birth Weight Estimation

Accurate fetal birth weight (FBW) estimation shortly before delivery is clinically valuable yet challenging due to its reliance on operator expertise, particularly in low-resource settings. To reduce this reliance, we study near-term birth-weight regression from blind-sweep ultrasound (US) videos acquired within 48 hours prior to delivery, with post-delivery weighing as ground truth. Accordingly, we propose a foundation model-driven key anatomy frame selection framework that enables accurate FBW regression despite the absence of plane constraints in blind sweeps. Our highlights are as follows: (1) We believe this is the first work to estimate FBW using blind-sweep US videos, enabling operator-independent assessment. (2) An Anatomy-Guided Frame Selection module equipped with a vision-language foundation model is proposed for keyframe collection in unconstrained sweeps. (3) A Redundancy-Aware Feature Compression module is designed to compress frame features while preserving task-relevant information, alleviating temporal redundancy. Extensively validated on prospectively collected data from 839 patients, our method achieves an MAE of 161.3 g, with 90.23% and 100% of cases falling within 10% and 15% absolute percentage error, outperforming typical Hadlock estimation and strong competitors. Codes are available at https://github.com/ouleoule/BlindSweep-EBW.

cs.CV

FrameONE: Hierarchical Motion Modeling for Universal Multi-View Echocardiographic Keyframe Detection

Accurate detection of end-systole (ES) and end-diastole (ED) frames is fundamental to echocardiographic assessment. Existing methods are typically developed in a view-specific manner, depend on auxiliary annotations or intensive visual modeling, which limits their generalizability. In multi-view modeling, keyframe detection is driven by shared cardiac motion, yet large appearance differences and motion patterns make unified modeling challenging. To address these issues, we propose FrameONE, a unified end-to-end framework for multi-view echocardiographic keyframe detection. FrameONE introduces a Hierarchical Motion Modeling strategy: an intra-view multi-task learning reduces appearance bias and promotes motion-focused representations within each view; an inter-view general motion learning module further separates view-agnostic dynamics from view-specific patterns, enabling shared yet flexible motion representation learning across views. Extensive experiments on 25,872 videos spanning four standard views demonstrate that FrameONE achieves state-of-the-art keyframe detection accuracy with strong cross-view generalization. Code is available at https://github.com/szuboy/FrameONE.

cs.CV

ClinRAG-GRAPH: Clinical-prior Retrieval-Augmented Graph Model with Domain Adversarial Learning for Breast pCR Prediction

Neoadjuvant chemotherapy (NAC) response prediction is clinically important for treatment stratification in breast cancer. However, robust pre-treatment pathological complete response (pCR) prediction remains challenging due to insufficient cross-modal modeling, multicenter imaging heterogeneity, and weak evidence-grounded interpretability. We propose ClinRAG-GRAPH, a Clinically informed Retrieval-Augmented Generation Graph framework, for pre-treatment pCR prediction from DCE-MRI, structured clinical variables, and biopsy-derived pathological biomarkers. ClinRAG-GRAPH constructs an intra-patient clinical-prior graph and applies a prior-guided relation-aware graph convolutional network for structured multimodal representation learning. To improve cross-center robustness, we introduce a dual-branch domain-adversarial learning strategy to suppress protocol-related MRI bias while preserving pCR-relevant features. To enhance interpretability, we further incorporate large language model (LLM)-driven subgraph RAG module that retrieves clinically analogous historical cases and integrates retrieved evidence for pCR inference. We assemble a large-scale multicenter NAC breast cancer cohort for extensive validation, drawing from two public sources and three in-house centers.Results show that ClinRAG-GRAPH achieves AUCs of 0.815 on the internal test set and 0.774/0.712 on two external test sets, demonstrating robust pre-treatment pCR prediction across centers. The code is available at the anonymized https://github.com/miccai26-1181/ClinRAG-GRAPH.

cs.CV

AI Data Centers and Power System Sustainability: Understanding the Sustainability Implications of AI-Driven Data Centers on Power Systems

The rapid expansion of artificial intelligence (AI) has driven unprecedented growth in data center electricity demand. The scale and pace of this load growth carry significant implications for the sustainability of electric power systems. On the one hand, rapid, spatially concentrated data center load growth is outpacing clean energy deployment in several major regions, raising emissions and challenging both grid flexibility and reliability. On the other hand, this fast-developing and capital-intensive sector offers abundant opportunities to advance sustainability through clean energy integration and operational innovations. This article provides an overview of the mechanisms through which data center affect power system sustainability, underscoring both risks and the potential. Specifically, this article (i) characterizes AI data center load behavior and categorizes electricity supply configurations by function and sustainability profile, as well as situates these loads within global and regional electricity demand trends; (ii) analyzes sustainability impacts across short-run operational and long-run planning mechanisms, evaluates effects on grid carbon emissions and renewable energy utilization, and feasibility of offering system flexibility and participating in ancillary service; and (iii) evaluates real-world corporate sustainability pathways and highlighting both the system benefits and feasibility limits of current carbon accounting practices. The goal of this work is to synthesize existing knowledge and technological developments and to guide research and development toward a more sustainable integration of AI data centers and electric power systems.

eess.SY

Overcoming noise-agility trade-off in integrated lasers for precision sensing

Lasers that combine narrow linewidths with rapid tunability are critical for applications such as coherent optical ranging, distributed fiber-optic sensing, and precision spectroscopy. Despite significant progress in integrated laser technologies, the concurrent realization of low phase noise and frequency agility on a single integrated platform remains challenging owing to a fundamental architectural trade-off: conventional integrated laser designs typically suppress phase noise via high-$Q$ resonators, yet the extended photon lifetimes inherent to such resonators intrinsically constrain tuning speed. Here, we address this noise-agility trade-off by introducing a laser architecture that achieves ultralow phase noise and ultrafast tunability simultaneously. Rather than relying on ultrahigh-$Q$ resonators for self-injection locking, our design employs strong synthetic feedback within a Pockels-tunable, resonator-enhanced distributed Bragg reflector to suppress phase noise. As a proof of concept, we demonstrate a hybrid integrated laser with a short-term linewidth of 29 Hz, realized using a lithium niobate external cavity with a loaded $Q$ of only 0.62 million. The adoption of a moderate resonator $Q$ relaxes the photon-lifetime constraint on tuning speed, enabling sub-exahertz-per-second tuning rates and a chirp nonlinearity as low as 0.14%. Leveraging this laser, we implement a frequency-modulated continuous-wave LiDAR system that achieves a relative ranging precision of $1.7 \times 10^{-4}$ at a measurement rate of $1\,\text{MSa s}^{-1}$, without requiring complex chirp linearization techniques. We further demonstrate fiber-optic acoustic sensing capable of detecting sub-$\mu\epsilon$ dynamic strain, underscoring the platform's versatility for high-speed precision optical measurements. Our work provides a route toward cost-effective yet high-performance sensing and metrology systems.

physics.optics

Meter-long broadband chirped Bragg gratings for on-chip dispersion control and pulse shaping

Precise on-chip dispersion control is essential for advanced integrated photonic technologies, enabling applications ranging from high-speed communications and sensing to signal processing and biomedical imaging. However, existing on-chip dispersion control methods still suffer from substantial loss and a limited dispersion-bandwidth product (DBP) far from application needs. As a result, on-chip systems continue to rely exclusively on off-chip dispersion control solutions provided by optical fiber or bulky free-space optics. To overcome these limitations, we design and fabricate meter-long chirped spiral Bragg gratings (CSBGs) on the ultra-low-loss silicon nitride (SiN) photonic platform for advanced dispersion control. Our device achieves a 10-nanosecond group delay with customizable bandwidths exceeding 10 nanometers within a compact footprint of only 30 $\text {mm} ^2$, surpassing the physical limits of fiber-based grating devices. More importantly, CSBGs can simultaneously possess the characteristics of high stability, low latency, and a large DBP, thanks to the ultra-low-loss SiN platform with a loss of only 0.3 dB/m. Leveraging the precise and stable dispersion profile, we demonstrate high-fidelity pulse shaping and compression of electro-optic frequency combs (EOCs) with a 1-GHz repetition rate centered across the entire reflection bandwidth. The compressed pulse has an on-chip peak (average) power of 21.6 watts (580 milliwatts). Furthermore, we showcase for the first time the application of on-chip pulse-compressed EOC in wavelength-swept coherent anti-Stokes Raman scattering (CARS) microscopy. Our work provides integrated photonics with a long-sought, scalable, and robust solution for high-performance on-chip dispersion control, empowering a new generation of on-chip functionalities.

physics.optics

Scalable 3D silicon nitride photonic interposer for high-density optical interconnects

Modern computing workloads demand energy-efficient, high-bandwidth interconnects, motivating photonic interposers as an alternative to electrical links. Here we demonstrate a compact 3D silicon nitride (SiN) photonic interposer prototype comprising two routing layers, with the 3D routing scheme optimized by a global optimization algorithm. The 3D interposer realizes a fully connected 12-node optical network that reduces the total number of intralayer crossings from 495 for all-planar routing to merely 150 (69.7% reduction), below the theoretical lower bound of 153 for all-planar interconnects. Comparing the two schemes, our 3D design achieves a 45.8% reduction experimentally in the average loss per waveguide. The proposed 3D routing architecture also features inherent symmetry and is scalable to higher node counts, flexible node placements, additional routing layers, and other operating wavelengths, enabling denser, lower-loss photonic interposers for next-generation scale-up and high-performance computing (HPC) systems.

physics.optics

Building reliable 3D photonic integrated circuits and cavities at the wafer scale

Three-dimensional (3D) photonic integrated circuits (PIC) are emerging as an indispensable scheme for high density and multifunctional photonic systems. However, the wafer-scale scaling of PICs towards a 3D configuration is constrained by two key factors: (i) the trade-off between inter-layer taper efficiency and footprint, and (ii) wafer-scale uniformity of inter-layer transition loss. In this work, we introduce etch-back assisted chemical mechanical polishing (E-CMP) to achieve high wafer-scale uniformity of the spacer layer. Moreover, we break the efficiency-footprint trade-off by demonstrating a novel $\kappa$-engineered taper, achieving a reliability metric that is 75\% higher than the traditional linearly tapered structure. Building on these design and fabrication developments, we enable reliable 3D PICs with typical loss of 0.077 and 0.068 dB/cm on two silicon nitride (SiN) waveguide layers and typical 3D transition loss as low as 6 mdB. Furthermore, the low 3D transition loss enables the first class of 3D high-Q optical cavities occupying two distinct device layers, providing new design space for high-Q optical cavities. The scalable fabrication process and design methodology provide routes for wafer-scale reliable 3D PICs that are promising in a series of applications ranging from photonic interconnects and computing networks to high-density photonic sensors and nonlinear photonics.

physics.optics

Artificial Intelligence for Detecting Fetal Orofacial Clefts and Advancing Medical Education

Orofacial clefts are among the most common congenital craniofacial abnormalities, yet accurate prenatal detection remains challenging due to the scarcity of experienced specialists and the relative rarity of the condition. Early and reliable diagnosis is essential to enable timely clinical intervention and reduce associated morbidity. Here we show that an artificial intelligence system, trained on over 45,139 ultrasound images from 9,215 fetuses across 22 hospitals, can diagnose fetal orofacial clefts with sensitivity and specificity exceeding 93% and 95% respectively, matching the performance of senior radiologists and substantially outperforming junior radiologists. When used as a medical copilot, the system raises junior radiologists' sensitivity by more than 6%. Beyond direct diagnostic assistance, the system also accelerates the development of clinical expertise. A pilot study involving 24 radiologists and trainees demonstrated that the model can improve the expertise development for rare conditions. This dual-purpose approach offers a scalable solution for improving both diagnostic accuracy and specialist training in settings where experienced radiologists are scarce.

cs.CV

FireRed-OCR Technical Report

We present FireRed-OCR, a systematic framework to specialize general VLMs into high-performance OCR models. Large Vision-Language Models (VLMs) have demonstrated impressive general capabilities but frequently suffer from ``structural hallucination'' when processing complex documents, limiting their utility in industrial OCR applications. In this paper, we introduce FireRed-OCR, a novel framework designed to transform general-purpose VLMs (based on Qwen3-VL) into pixel-precise structural document parsing experts. To address the scarcity of high-quality structured data, we construct a ``Geometry + Semantics'' Data Factory. Unlike traditional random sampling, our pipeline leverages geometric feature clustering and multi-dimensional tagging to synthesize and curate a highly balanced dataset, effectively handling long-tail layouts and rare document types. Furthermore, we propose a Three-Stage Progressive Training strategy that guides the model from pixel-level perception to logical structure generation. This curriculum includes: (1) Multi-task Pre-alignment to ground the model's understanding of document structure; (2) Specialized SFT for standardizing full-image Markdown output; and (3) Format-Constrained Group Relative Policy Optimization (GRPO), which utilizes reinforcement learning to enforce strict syntactic validity and structural integrity (e.g., table closure, formula syntax). Extensive evaluations on OmniDocBench v1.5 demonstrate that FireRed-OCR achieves state-of-the-art performance with an overall score of 92.94\%, significantly outperforming strong baselines such as DeepSeek-OCR 2 and OCRVerse across text, formula, table, and reading order metrics. We open-source our code and model weights to facilitate the ``General VLM to Specialized Structural Expert'' paradigm.

cs.CV

FireRed-Image-Edit-1.0 Technical Report

We present FireRed-Image-Edit, a diffusion transformer for instruction-based image editing that achieves state-of-the-art performance through systematic optimization of data curation, training methodology, and evaluation design. We construct a 1.6B-sample training corpus, comprising 900M text-to-image and 700M image editing pairs from diverse sources. After rigorous cleaning, stratification, auto-labeling, and two-stage filtering, we retain over 100M high-quality samples balanced between generation and editing, ensuring strong semantic coverage and instruction alignment. Our multi-stage training pipeline progressively builds editing capability via pre-training, supervised fine-tuning, and reinforcement learning. To improve data efficiency, we introduce a Multi-Condition Aware Bucket Sampler for variable-resolution batching and Stochastic Instruction Alignment with dynamic prompt re-indexing. To stabilize optimization and enhance controllability, we propose Asymmetric Gradient Optimization for DPO, DiffusionNFT with layout-aware OCR rewards for text editing, and a differentiable Consistency Loss for identity preservation. We further establish REDEdit-Bench, a comprehensive benchmark spanning 15 editing categories, including newly introduced beautification and low-level enhancement tasks. Extensive experiments on REDEdit-Bench and public benchmarks (ImgEdit and GEdit) demonstrate competitive or superior performance against both open-source and proprietary systems. To support future research, our code, models, and benchmark suite are publicly available at https://github.com/FireRedTeam/FireRed-Image-Edit/ .

cs.CV

RMFlow: Refined Mean Flow by a Noise-Injection Step for Multimodal Generation

Mean flow (MeanFlow) enables efficient, high-fidelity image generation, yet its single-function evaluation (1-NFE) generation often cannot yield compelling results. We address this issue by introducing RMFlow, an efficient multimodal generative model that integrates a coarse 1-NFE MeanFlow transport with a subsequent tailored noise-injection refinement step. RMFlow approximates the average velocity of the flow path using a neural network trained with a new loss function that balances minimizing the Wasserstein distance between probability paths and maximizing sample likelihood. RMFlow achieves near state-of-the-art results on text-to-image, context-to-molecule, and time-series generation using only 1-NFE, at a computational cost comparable to the baseline MeanFlows.

cs.LG

Towards Multiscale Graph-based Protein Learning with Geometric Secondary Structural Motifs

Graph neural networks (GNNs) have emerged as powerful tools for learning protein structures by capturing spatial relationships at the residue level. However, existing GNN-based methods often face challenges in learning multiscale representations and modeling long-range dependencies efficiently. In this work, we propose an efficient multiscale graph-based learning framework tailored to proteins. Our proposed framework contains two crucial components: (1) It constructs a hierarchical graph representation comprising a collection of fine-grained subgraphs, each corresponding to a secondary structure motif (e.g., $\alpha$-helices, $\beta$-strands, loops), and a single coarse-grained graph that connects these motifs based on their spatial arrangement and relative orientation. (2) It employs two GNNs for feature learning: the first operates within individual secondary motifs to capture local interactions, and the second models higher-level structural relationships across motifs. Our modular framework allows a flexible choice of GNN in each stage. Theoretically, we show that our hierarchical framework preserves the desired maximal expressiveness, ensuring no loss of critical structural information. Empirically, we demonstrate that integrating baseline GNNs into our multiscale framework remarkably improves prediction accuracy and reduces computational cost across various benchmarks.

cs.LG