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Yuli Wang

Publications and source records attributed to Yuli Wang.

14 recordsLinked to original sources

SurgRFO: Foundation Model Based Compositional Synthesis of Critical Retained Foreign Objects in Intraoperative Chest X-rays

Critical retained foreign objects (RFOs) on intraoperative chest radiographs are rare but high-risk events. Their scarcity limits robust automated detection model training and generalization. We introduce SurgRFO, a two-stage synthesis framework for generating realistic RFO-present intraoperative chest X-rays. In Stage 1, a Roentgen chest X-ray foundation model is fine-tuned on surgical-domain images to generate realistic RFO-free backgrounds that preserve anatomy, indwelling lines and tubes, and intraoperative imaging characteristics. In Stage 2, a lightweight generator trained on localized RFO patches from limited positive cases synthesizes diverse RFO instances, which are composited onto generated backgrounds using conditional Poisson fusion to improve photometric consistency. We evaluate SurgRFO through (i) a blinded clinician study assessing realism and clinical plausibility, and (ii) downstream detection experiments in which synthesized data are used to augment Faster R-CNN, YOLOv8, and RetinaNet. SurgRFO consistently improves sensitivity at low false-positive-per-image (FPPI) operating points on internal and external test sets. Clinician ratings indicate that the synthesized images achieve realism comparable to real intraoperative images. Ablation analyses further examine fusion strategies and synthesis scale. Ethical safeguards for synthetic surgical data are also discussed.

eess.IV

Self-Supervised Contrastive Learning for Cardiac MR Sequence Classification

Vision Transformer (ViT) models, utilizing self-attention mechanisms, have demonstrated robust generalization capabilities across various vision tasks, including image classification. However, these models, typically pretrained on general public datasets, often lack the specialized domain knowledge necessary for medical imaging applications. In this study, we investigate the adaptation of ViT models, specifically for cardiac magnetic resonance (MR) images, using an in-house dataset. We found that pretrained ViT features do not effectively transfer to the cardiac MR domain. To overcome this limitation, we introduce an adaptation strategy that utilizes image-based self-supervised contrastive learning, demonstrating superior performance compared to traditional supervised training approaches. Moreover, our adapted ViT model exhibits strong generalization to external MR datasets such as BraTS and ADNI. Through ablation studies, we further investigate the impact of batch size and dataset scale on performance. Ultimately, our adapted model achieves classification AUC exceeding 0.75 across the four most common cardiac MR sequences.

cs.CV

A multitask framework for automated interpretation of multi-frame right upper quadrant ultrasound in clinical decision support

Ultrasound is a cornerstone of emergency and hepatobiliary imaging, yet its interpretation remains highly operator-dependent and time-sensitive. Here, we present a multitask vision-language agent (VLM) developed to assist with comprehensive right upper quadrant (RUQ) ultrasound interpretation across the full diagnostic workflow. The system was trained on a large, multi-center dataset comprising a primary cohort from Johns Hopkins Medical Institutions (9,189 cases, 594,099 images) and externally validated on cohorts from Stanford University (108 cases, 3,240 images) and a major Chinese medical center (257 cases, 3,178 images). Built on the Qwen2.5-VL-7B architecture, the agent integrates frame-level visual understanding with report-grounded language reasoning to perform three tasks: (i) classification of 18 hepatobiliary and gallbladder conditions, (ii) generation of clinically coherent diagnostic reports, and (iii) surgical decision support based on ultrasound findings and clinical data. The model achieved high diagnostic accuracy across all tasks, generated reports that were indistinguishable from expert-written versions in blinded evaluations, and demonstrated superior factual accuracy and information density on content-based metrics. The agent further identified patients requiring cholecystectomy with high precision, supporting real-time decision-making. These results highlight the potential of generalist vision-language models to improve diagnostic consistency, reporting efficiency, and surgical triage in real-world ultrasound practice.

eess.IV

Dataset and Benchmark for Enhancing Critical Retained Foreign Object Detection

Critical retained foreign objects (RFOs), including surgical instruments like sponges and needles, pose serious patient safety risks and carry significant financial and legal implications for healthcare institutions. Detecting critical RFOs using artificial intelligence remains challenging due to their rarity and the limited availability of chest X-ray datasets that specifically feature critical RFOs cases. Existing datasets only contain non-critical RFOs, like necklace or zipper, further limiting their utility for developing clinically impactful detection algorithms. To address these limitations, we introduce "Hopkins RFOs Bench", the first and largest dataset of its kind, containing 144 chest X-ray images of critical RFO cases collected over 18 years from the Johns Hopkins Health System. Using this dataset, we benchmark several state-of-the-art object detection models, highlighting the need for enhanced detection methodologies for critical RFO cases. Recognizing data scarcity challenges, we further explore image synthetic methods to bridge this gap. We evaluate two advanced synthetic image methods, DeepDRR-RFO, a physics-based method, and RoentGen-RFO, a diffusion-based method, for creating realistic radiographs featuring critical RFOs. Our comprehensive analysis identifies the strengths and limitations of each synthetic method, providing insights into effectively utilizing synthetic data to enhance model training. The Hopkins RFOs Bench and our findings significantly advance the development of reliable, generalizable AI-driven solutions for detecting critical RFOs in clinical chest X-rays.

eess.IV

Abn-BLIP: Abnormality-aligned Bootstrapping Language-Image Pre-training for Pulmonary Embolism Diagnosis and Report Generation from CTPA

Medical imaging plays a pivotal role in modern healthcare, with computed tomography pulmonary angiography (CTPA) being a critical tool for diagnosing pulmonary embolism and other thoracic conditions. However, the complexity of interpreting CTPA scans and generating accurate radiology reports remains a significant challenge. This paper introduces Abn-BLIP (Abnormality-aligned Bootstrapping Language-Image Pretraining), an advanced diagnosis model designed to align abnormal findings to generate the accuracy and comprehensiveness of radiology reports. By leveraging learnable queries and cross-modal attention mechanisms, our model demonstrates superior performance in detecting abnormalities, reducing missed findings, and generating structured reports compared to existing methods. Our experiments show that Abn-BLIP outperforms state-of-the-art medical vision-language models and 3D report generation methods in both accuracy and clinical relevance. These results highlight the potential of integrating multimodal learning strategies for improving radiology reporting. The source code is available at https://github.com/zzs95/abn-blip.

cs.CV

Evaluating unsupervised contrastive learning framework for MRI sequences classification

The automatic identification of Magnetic Resonance Imaging (MRI) sequences can streamline clinical workflows by reducing the time radiologists spend manually sorting and identifying sequences, thereby enabling faster diagnosis and treatment planning for patients. However, the lack of standardization in the parameters of MRI scans poses challenges for automated systems and complicates the generation and utilization of datasets for machine learning research. To address this issue, we propose a system for MRI sequence identification using an unsupervised contrastive deep learning framework. By training a convolutional neural network based on the ResNet-18 architecture, our system classifies nine common MRI sequence types as a 9-class classification problem. The network was trained using an in-house internal dataset and validated on several public datasets, including BraTS, ADNI, Fused Radiology-Pathology Prostate Dataset, the Breast Cancer Dataset (ACRIN), among others, encompassing diverse acquisition protocols and requiring only 2D slices for training. Our system achieves a classification accuracy of over 0.95 across the nine most common MRI sequence types.

cs.CV

Optimizing Prompt Strategies for SAM: Advancing lesion Segmentation Across Diverse Medical Imaging Modalities

Purpose: To evaluate various Segmental Anything Model (SAM) prompt strategies across four lesions datasets and to subsequently develop a reinforcement learning (RL) agent to optimize SAM prompt placement. Materials and Methods: This retrospective study included patients with four independent ovarian, lung, renal, and breast tumor datasets. Manual segmentation and SAM-assisted segmentation were performed for all lesions. A RL model was developed to predict and select SAM points to maximize segmentation performance. Statistical analysis of segmentation was conducted using pairwise t-tests. Results: Results show that increasing the number of prompt points significantly improves segmentation accuracy, with Dice coefficients rising from 0.272 for a single point to 0.806 for five or more points in ovarian tumors. The prompt location also influenced performance, with surface and union-based prompts outperforming center-based prompts, achieving mean Dice coefficients of 0.604 and 0.724 for ovarian and breast tumors, respectively. The RL agent achieved a peak Dice coefficient of 0.595 for ovarian tumors, outperforming random and alternative RL strategies. Additionally, it significantly reduced segmentation time, achieving a nearly 10-fold improvement compared to manual methods using SAM. Conclusion: While increased SAM prompts and non-centered prompts generally improved segmentation accuracy, each pathology and modality has specific optimal thresholds and placement strategies. Our RL agent achieved superior performance compared to other agents while achieving a significant reduction in segmentation time.

eess.IV

Is Registering Raw Tagged-MR Enough for Strain Estimation in the Era of Deep Learning?

Magnetic Resonance Imaging with tagging (tMRI) has long been utilized for quantifying tissue motion and strain during deformation. However, a phenomenon known as tag fading, a gradual decrease in tag visibility over time, often complicates post-processing. The first contribution of this study is to model tag fading by considering the interplay between $T_1$ relaxation and the repeated application of radio frequency (RF) pulses during serial imaging sequences. This is a factor that has been overlooked in prior research on tMRI post-processing. Further, we have observed an emerging trend of utilizing raw tagged MRI within a deep learning-based (DL) registration framework for motion estimation. In this work, we evaluate and analyze the impact of commonly used image similarity objectives in training DL registrations on raw tMRI. This is then compared with the Harmonic Phase-based approach, a traditional approach which is claimed to be robust to tag fading. Our findings, derived from both simulated images and an actual phantom scan, reveal the limitations of various similarity losses in raw tMRI and emphasize caution in registration tasks where image intensity changes over time.

eess.IV

Efficient Annotation for Medical Image Analysis: A One-Pass Selective Annotation Approach

Annotating biomedical images for supervised learning is a complex and labor-intensive task due to data diversity and its intricate nature. In this paper, we propose an innovative method, the efficient one-pass selective annotation (EPOSA), that significantly reduces the annotation burden while maintaining robust model performance. Our approach employs a variational autoencoder (VAE) to extract salient features from unannotated images, which are subsequently clustered using the DBSCAN algorithm. This process groups similar images together, forming distinct clusters. We then use a two-stage sample selection algorithm, called representative selection (RepSel), to form a selected dataset. The first stage is a Markov Chain Monte Carlo (MCMC) sampling technique to select representative samples from each cluster for annotations. This selection process is the second stage, which is guided by the principle of maximizing intra-cluster mutual information and minimizing inter-cluster mutual information. This ensures a diverse set of features for model training and minimizes outlier inclusion. The selected samples are used to train a VGG-16 network for image classification. Experimental results on the Med-MNIST dataset demonstrate that our proposed EPOSA outperforms random selection and other state-of-the-art methods under the same annotation budget, presenting a promising direction for efficient and effective annotation in medical image analysis.

eess.IV

Optimal operating MR contrast for brain ventricle parcellation

Development of MR harmonization has enabled different contrast MRIs to be synthesized while preserving the underlying anatomy. In this paper, we use image harmonization to explore the impact of different T1-w MR contrasts on a state-of-the-art ventricle parcellation algorithm VParNet. We identify an optimal operating contrast (OOC) for ventricle parcellation; by showing that the performance of a pretrained VParNet can be boosted by adjusting contrast to the OOC.

eess.IV

Label Propagation via Random Walk for Training Robust Thalamus Nuclei Parcellation Model from Noisy Annotations

Data-driven thalamic nuclei parcellation depends on high-quality manual annotations. However, the small size and low contrast changes among thalamic nuclei, yield annotations that are often incomplete, noisy, or ambiguously labelled. To train a robust thalamic nuclei parcellation model with noisy annotations, we propose a label propagation algorithm based on random walker to refine the annotations before model training. A two-step model was trained to generate first the whole thalamus and then the nuclei masks. We conducted experiments on a mild traumatic brain injury~(mTBI) dataset with noisy thalamic nuclei annotations. Our model outperforms current state-of-the-art thalamic nuclei parcellations by a clear margin. We believe our method can also facilitate the training of other parcellation models with noisy labels.

eess.IV

Performance investigations of two channel readout configurations on the cross-strip cadmium zinc telluride detector

Multiple application-specific integrated circuits (ASIC) are required for the detectors if their readout channels are larger than that of ASIC channels. For a system with such a readout scheme, there is a need to configure channels among ASICs to achieve the lowest electronics noise and highest count rate. In this work, experiments were performed to investigate the performance of two different readout configurations between two ASICs in a cross-strip cadmium zinc telluride detector. A lower electronic noise level, better FWHM energy resolution performance, and higher count rate was found for the anode electrode strips with each ASIC allocating half of the detector area when compared to allocating each ASIC channel to alternate anode channels.

physics.ins-det

Automated Ventricle Parcellation and Evan's Ratio Computation in Pre- and Post-Surgical Ventriculomegaly

Normal pressure hydrocephalus~(NPH) is a brain disorder associated with enlarged ventricles and multiple cognitive and motor symptoms. The degree of ventricular enlargement can be measured using magnetic resonance images~(MRIs) and characterized quantitatively using the Evan's ratio (ER). Automatic computation of ER is desired to avoid the extra time and variations associated with manual measurements on MRI. Because shunt surgery is often used to treat NPH, it is necessary that this process be robust to image artifacts caused by the shunt and related implants. In this paper, we propose a 3D regions-of-interest aware (ROI-aware) network for segmenting the ventricles. The method achieves state-of-the-art performance on both pre-surgery MRIs and post-surgery MRIs with artifacts. Based on our segmentation results, we also describe an automated approach to compute ER from these results. Experimental results on multiple datasets demonstrate the potential of the proposed method to assist clinicians in the diagnosis and management of NPH.

eess.IV

Local dissipation limits the dynamics of impacting droplets on smooth and rough substrates

A droplet that impacts onto a solid substrate deforms in a complex dynamics. To extract the principal mechanisms that dominate this dynamics we deploy numerical simulations based on the phase field method. Direct comparison with experiments suggests that a dissipation local to the contact line limits the droplet spreading dynamics and its scaled maximum spreading radius $β_\mathrm{max}$. By assuming linear response through a drag force at the contact line, our simulations rationalize experimental observations for droplet impact on both smooth and rough substrates, measured through a single contact line friction parameter $μ_f$. Moreover, our analysis shows that at low and intermediate impact speeds dissipation at the contact line limits the dynamics and we describe $β_\mathrm{max}$ by the scaling law $β_\mathrm{max} \sim (Re μ_\mathrm{l}/μ_f)^{1/2}$ that is a function of the droplet viscosity ($μ_\mathrm{l}$) and its Reynolds number ($Re$).

physics.flu-dyn