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Yun-Hsuan Chen

Publications and source records attributed to Yun-Hsuan Chen.

6 recordsLinked to original sources

Quantum Parrondo Paradox via a Single Phase Defect Symmetry Breaking and Directed Transport

Parrondo paradox describes the counterintuitive phenomenon in which alternating two individually losing games yields a winning outcome. Extending this effect to the quantum regime has typically required high dimensional coin spaces, entangled initial states, or engineered decoherence. Here we show that a genuine and persistent quantum Parrondo effect can be realized with minimal resources a single-qubit coin, a fixed periodic sequence of two SU (2) operators, and a single localized phase defect at the origin of a discrete-time quantum walk. By breaking translational symmetry, the phase defect acts as a scattering center that enables momentum mixing and interference-induced rectification, converting two losing games into a directed quantum ratchet. We critically reassess the winning criterion and demonstrate that the position expectation value, rather than the commonly used probability asymmetry, is the appropriate metric for validating the paradox. Harmonic analysis of the drift velocity reveals a complex, resonance type dependence with high-order Fourier components, reflecting nontrivial multi-path interference at the defect site. We further show that winning strategies are associated with cyclic restoration of coin-position entanglement, and that the ratchet effect is robust across a wide range of initial states. Our results establish that spatial inhomogeneity, rather than additional quantum resources, is the essential ingredient for a sustainable quantum Parrondo effect, offering a resource efficient blueprint for directed transport on near-term quantum platforms.

quant-ph↗

A Synchronous EEG-fNIRS BCI: A Proof-of-Concept for Multimodal Avalanche Analysis of Motor Cognition in Older Adults

This proof-of-concept study introduces a novel multimodal framework combining synchronized EEG-fNIRS modalities with neuronal avalanche analysis to identify early network dysfunction in Alzheimer's disease. The approach leverages complementary neural signals to examine motor network dynamics during execution and imagery tasks within an interactive task environment. Preliminary analysis of a small pilot cohort (N=4 subjects, including one with Mild Cognitive Impairment) validated the technical feasibility of the multimodal framework and revealed observable condition-dependent patterns in network organization. Two primary observations emerged: a reduced neural contrast between motor execution and imagery states, and increased trial-to-trial variability in network organization in the MCI participant. These initial results successfully validate the technical pipeline and provide hypothesis-generating observations for future statistically powered studies. The convergence of findings across modalities suggests that multimodal assessment of network flexibility may help detect functional changes in early Alzheimer's continuum, supporting the future development of this BCI-inspired framework into an engaging diagnostic tool.

q-bio.NC↗

Meta-Learning for GPU-Accelerated Quantum Many-Body Problems

We explore the industrial and scientific applicability of the VQE-LSTM framework by integrating meta-learning with GPU accelerated quantum simulation using NVIDIA's CUDA-Q (CUDAQ) platform. This work demonstrates how an LSTM-FC meta-initialization module can extend the practical reach of the Variational Quantum Eigensolver (VQE) in both chemistry and physics domains. In the chemical regime, the framework predicts ground-state energies of molecular Hamiltonians derived from PySCF, achieving near FCI accuracy while maintaining favorable O(N^2) scaling with molecular size. In the physical counterpart, we applied the same model to quantized Simple Harmonic Motion systems (SHM), successfully reproducing its ground and excited states through VQE and Variational Quantum Deflation (VQD) methods. Benchmark results on NVIDIA GPUs reveal significant speedups over CPU-based implementations, validating CUDAQ's capability to handle large-scale variational workloads efficiently. Overall, this study establishes VQE-LSTM as a viable and scalable approach for GPU accelerated quantum simulation, bridging quantum chemistry and condensed-matter physics through a unified, meta-learned initialization strategy.

quant-ph↗

Repetitive TMS-based Identification of Methamphetamine-Dependent Individuals Using EEG Spectra

The impact of repetitive transcranial magnetic stimulation (rTMS) on methamphetamine (METH) users' craving levels is often assessed using questionnaires. This study explores the feasibility of using neural signals to obtain more objective results. EEG signals recorded from 20 METH-addicted participants Before and After rTMS (MBT and MAT) and from 20 healthy participants (HC) are analyzed. In each EEG paradigm, participants are shown 15 METH-related and 15 neutral pictures randomly, and the relative band power (RBP) of each EEG sub-band frequency is derived. The average RBP across all 31 channels, as well as individual brain regions, is analyzed. Statistically, MAT's alpha, beta, and gamma RBPs are more like those of HC compared to MBT, as indicated by the power topographies. Utilizing a random forest (RF), the gamma RBP is identified as the optimal frequency band for distinguishing between MBT and HC with a 90% accuracy. The performance of classifying MAT versus HC is lower than that of MBT versus HC, suggesting that the efficacy of rTMS can be validated using RF with gamma RBP. Furthermore, the gamma RBP recorded by the TP10 and CP2 channels dominates the classification task of MBT versus HC when receiving METH-related image cues. The gamma RBP during exposure to METH-related cues can serve as a biomarker for distinguishing between MBT and HC and for evaluating the effectiveness of rTMS. Therefore, real-time monitoring of gamma RBP variations holds promise as a parameter for implementing a customized closed-loop neuromodulation system for treating METH addiction.

q-bio.NC↗

NeuroCLIP: A Multimodal Contrastive Learning Method for rTMS-treated Methamphetamine Addiction Analysis

Methamphetamine dependence poses a significant global health challenge, yet its assessment and the evaluation of treatments like repetitive transcranial magnetic stimulation (rTMS) frequently depend on subjective self-reports, which may introduce uncertainties. While objective neuroimaging modalities such as electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) offer alternatives, their individual limitations and the reliance on conventional, often hand-crafted, feature extraction can compromise the reliability of derived biomarkers. To overcome these limitations, we propose NeuroCLIP, a novel deep learning framework integrating simultaneously recorded EEG and fNIRS data through a progressive learning strategy. This approach offers a robust and trustworthy biomarker for methamphetamine addiction. Validation experiments show that NeuroCLIP significantly improves discriminative capabilities among the methamphetamine-dependent individuals and healthy controls compared to models using either EEG or only fNIRS alone. Furthermore, the proposed framework facilitates objective, brain-based evaluation of rTMS treatment efficacy, demonstrating measurable shifts in neural patterns towards healthy control profiles after treatment. Critically, we establish the trustworthiness of the multimodal data-driven biomarker by showing its strong correlation with psychometrically validated craving scores. These findings suggest that biomarker derived from EEG-fNIRS data via NeuroCLIP offers enhanced robustness and reliability over single-modality approaches, providing a valuable tool for addiction neuroscience research and potentially improving clinical assessments.

eess.SP↗

VSViG: Real-time Video-based Seizure Detection via Skeleton-based Spatiotemporal ViG

An accurate and efficient epileptic seizure onset detection can significantly benefit patients. Traditional diagnostic methods, primarily relying on electroencephalograms (EEGs), often result in cumbersome and non-portable solutions, making continuous patient monitoring challenging. The video-based seizure detection system is expected to free patients from the constraints of scalp or implanted EEG devices and enable remote monitoring in residential settings. Previous video-based methods neither enable all-day monitoring nor provide short detection latency due to insufficient resources and ineffective patient action recognition techniques. Additionally, skeleton-based action recognition approaches remain limitations in identifying subtle seizure-related actions. To address these challenges, we propose a novel Video-based Seizure detection model via a skeleton-based spatiotemporal Vision Graph neural network (VSViG) for its efficient, accurate and timely purpose in real-time scenarios. Our experimental results indicate VSViG outperforms previous state-of-the-art action recognition models on our collected patients' video data with higher accuracy (5.9% error), lower FLOPs (0.4G), and smaller model size (1.4M). Furthermore, by integrating a decision-making rule that combines output probabilities and an accumulative function, we achieve a 5.1 s detection latency after EEG onset, a 13.1 s detection advance before clinical onset, and a zero false detection rate. The project homepage is available at: https://github.com/xuyankun/VSViG/

cs.CV↗