arXiv subjects

Yunqi Yang

Publications and source records attributed to Yunqi Yang.

3 recordsLinked to original sources

arXiv2026

CoMAI: A Collaborative Multi-Agent Framework for Robust and Equitable Interview Evaluation

Ensuring robust and fair interview assessment remains a key challenge in AI-driven evaluation. This paper presents CoMAI, a general-purpose multi-agent interview framework designed for diverse assessment scenarios. In contrast to monolithic single-agent systems based on large language models (LLMs), CoMAI employs a modular task-decomposition architecture coordinated through a centralized finite-state machine. The system comprises four agents specialized in question generation, security, scoring, and summarization. These agents work collaboratively to provide multi-layered security defenses against prompt injection, support multidimensional evaluation with adaptive difficulty adjustment, and enable rubric-based structured scoring that reduces subjective bias. Experimental results demonstrate that CoMAI achieved 90.47% accuracy, 83.33% recall, and 84.41% candidate satisfaction. These results highlight CoMAI as a robust, fair, and interpretable paradigm for AI-driven interview assessment.

cs.MA↗

arXiv2025

Bayesian variable selection in a Cox proportional hazards model with the "Sum of Single Effects" prior

Motivated by genetic fine-mapping applications, we introduce a new approach to Bayesian variable selection regression (BVSR) for time-to-event (TTE) outcomes. This new approach is designed to deal with the specific challenges that arise in genetic fine-mapping, including: the presence of very strong correlations among the covariates, often exceeding 0.99; very large data sets containing potentially thousands of covariates and hundreds of thousands of samples. We accomplish this by extending the "Sum of Single Effects" (SuSiE) method to the Cox proportional hazards (CoxPH) model. We demonstrate the benefits of the new method, "CoxPH-SuSiE", over existing BVSR methods for TTE outcomes in simulated fine-mapping data sets. We also illustrate CoxPH-SuSiE on real data by fine-mapping asthma loci using data from UK Biobank. This fine-mapping identified 14 asthma risk SNPs in 8 asthma risk loci, among which 6 had strong evidence for being causal (posterior inclusion probability greater than 50%). Two of the 6 putatively causal variants are known to be pathogenic, and others lie within a genomic sequence that is known to regulate the expression of GATA3.

stat.ME↗

arXiv2024

Improved methods for empirical Bayes multivariate multiple testing and effect size estimation

Estimating the sharing of genetic effects across different conditions is important to many statistical analyses of genomic data. The patterns of sharing arising from these data are often highly heterogeneous. To flexibly model these heterogeneous sharing patterns, Urbut et al. (2019) proposed the multivariate adaptive shrinkage (MASH) method to jointly analyze genetic effects across multiple conditions. However, multivariate analyses using MASH (as well as other multivariate analyses) require good estimates of the sharing patterns, and estimating these patterns efficiently and accurately remains challenging. Here we describe new empirical Bayes methods that provide improvements in speed and accuracy over existing methods. The two key ideas are: (1) adaptive regularization to improve accuracy in settings with many conditions; (2) improving the speed of the model fitting algorithms by exploiting analytical results on covariance estimation. In simulations, we show that the new methods provide better model fits, better out-of-sample performance, and improved power and accuracy in detecting the true underlying signals. In an analysis of eQTLs in 49 human tissues, our new analysis pipeline achieves better model fits and better out-of-sample performance than the existing MASH analysis pipeline. We have implemented the new methods, which we call ``Ultimate Deconvolution'', in an R package, udr, available on GitHub.

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