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Yunshen Chen

Publications and source records attributed to Yunshen Chen.

2 recordsLinked to original sources

Deep learning-based pavement performance modeling using multiple distress indicators and road work history

The deterioration of pavement is a complex and dynamic process determined by different factors including material, environment, design, and some other unobserved variables. Accurate predictions of pavement condition can help maximize the use of available resources for pavement management agencies through better coordinated preservation and maintenance activities. This paper uses deep neural networks such as the convolutional neural network (CNN) and the long short-term memory (LSTM) to model the pavement deterioration process. In this paper, pavement condition data and maintenance and rehabilitation history collected by the Texas Department of Transportation over the past 18 years were used. Twenty-one flexible pavement condition indicators, including cracking, rutting, raveling, and roughness, collected from more than 100,000 pavement sections were included in the proposed models. Promising preliminary results were obtained. Case study results show that the proposed CNN model outperforms standard machine learning models in predicting pavement condition values.

cs.LG

Count-based differential expression analysis of RNA sequencing data using R and Bioconductor

RNA sequencing (RNA-seq) has been rapidly adopted for the profiling of transcriptomes in many areas of biology, including studies into gene regulation, development and disease. Of particular interest is the discovery of differentially expressed genes across different conditions (e.g., tissues, perturbations), while optionally adjusting for other systematic factors that affect the data collection process. There are a number of subtle yet critical aspects of these analyses, such as read counting, appropriate treatment of biological variability, quality control checks and appropriate setup of statistical modeling. Several variations have been presented in the literature, and there is a need for guidance on current best practices. This protocol presents a "state-of-the-art" computational and statistical RNA-seq differential expression analysis workflow largely based on the free open-source R language and Bioconductor software and in particular, two widely-used tools DESeq and edgeR. Hands-on time for typical small experiments (e.g., 4-10 samples) can be <1 hour, with computation time <1 day using a standard desktop PC.

q-bio.GN