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Yuqi Tang

Publications and source records attributed to Yuqi Tang.

20 records · Page 2Linked to original sources

XAlgo: a Design Probe of Explaining Algorithms' Internal States via Question-Answering

Algorithms often appear as 'black boxes' to non-expert users. While prior work focuses on explainable representations and expert-oriented exploration, we propose and study an interactive approach using question answering to explain deterministic algorithms to non-expert users who need to understand the algorithms' internal states (e.g., students learning algorithms, operators monitoring robots, admins troubleshooting network routing). We construct XAlgo -- a formal model that first classifies the type of question based on a taxonomy and generates an answer based on a set of rules that extract information from representations of an algorithm's internal states, e.g., the pseudocode. A design probe in an algorithm learning scenario with 18 participants (9 for a Wizard-of-Oz XAlgo and 9 as a control group) reports findings and design implications based on what kinds of questions people ask, how well XAlgo responds, and what remain as challenges to bridge users' gulf of understanding algorithms.

cs.HC↗

3D Monte Carlo Simulation of Light Distribution in Mouse Brain in Quantitative Photoacoustic Computed Tomography

Photoacoustic computed tomography (PACT) detects light-induced ultrasound waves to reconstruct the optical absorption contrast of the biological tissues. Due to its relatively deep penetration (several centimeters in soft tissue), high spatial resolution, and inherent functional sensitivity, PACT has great potential for imaging mouse brains with endogenous and exogenous contrasts, which is of immense interest to the neuroscience community. However, conventional PACT either assumes homogenous optical fluence within the brain or uses a simplified attenuation model for optical fluence estimation. Both approaches underestimate the complexity of the fluence heterogeneity and can result in poor quantitative imaging accuracy. To optimize the quantitative performance of PACT, we explore for the first time 3D Monte Carlo simulation to study the optical fluence distribution in a complete mouse brain model. We apply the MCX Monte Carlo simulation package on a digital mouse (Digimouse) brain atlas that has complete anatomy information. To evaluate the impact of the brain vasculature on light delivery, we also incorporate the whole-brain vasculature in the Digimouse atlas. The simulation results clearly show that the optical fluence in the mouse brain is heterogeneous at the global level and can decrease by a factor of five with increasing depth. Moreover, the strong absorption and scattering of the brain vasculature also induce the fluence disturbance at the local level. Our results suggest that both global and local fluence heterogeneity contributes to the reduced quantitative accuracy of the reconstructed PACT images of mouse brain.

physics.med-ph↗