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Yuyang Zheng

Publications and source records attributed to Yuyang Zheng.

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Valhalla: A Layered Knowledge-State and Service-Governance Framework for Long-Term Scientific Knowledge Work

As large language model (LLM) agents are increasingly adopted in scientific research, external knowledge bases, knowledge graphs, and long-term memory have improved information retrieval and task continuity. However, most structured knowledge systems remain node-centric, representing files, concepts, results, and judgments as nodes and relations in a graph. While suitable for personal knowledge management, such structures often depend on individual organizational practices, limiting knowledge sharing, integration, and reorganization across users. This paper presents Valhalla, a layered knowledge-state and service-governance framework for long-term scientific knowledge work. Valhalla replaces flat graphs with layered encapsulation and stable semantic boundaries through a five-layer File-Resource-Entity-Relationship-Graph (FREG) model. File and Resource preserve source identity and provenance, Entity represents knowledge objects, Relationship captures semantic judgments, and Graph provides task-oriented knowledge views, enabling knowledge states from different researchers to be exchanged and reorganized under a unified structure. We further introduce a Router-Contract-Workflow service-governance architecture, inspired by the microkernel paradigm, to constrain how language models access, modify, and extend knowledge states while maintaining structural consistency and auditable operational boundaries. We implement a Valhalla prototype and validate knowledge ingestion, cross-member integration, and scientific writing support through an antibody-design review task comprising 26 paper resources, 80 knowledge entities, and 92 semantic relations. Rather than proposing a new knowledge-extraction algorithm, Valhalla offers a paradigm for organizing collaborative scientific knowledge, transforming individualized knowledge structures into transferable and reorganizable shared knowledge states.

q-bio.NC

Reactive polar mesogenic self-assembly approach enables domain-programmable polymer ferroelectrics

Ferroelectric polymers combine switchable polarization with the processability of soft materials, but their development has been dominated by poly(vinylidene fluoride) and related fluoropolymers, whose crystalline polar phases restrict mechanical compliance and domain design with spatial precision. Here we establish a generic design principle for creating intrinsically flexible ferroelectric liquid-crystal polymers through reactive polar mesogenic self-assembly. The approach creates polyfluoroalkyl-free polymer films in which robust ferroelectric order arises from liquid-crystalline molecular organization rather than crystalline phase formation. By transferring ferroelectric order from fluid mesogenic states into polymer networks, the resulting materials combine mechanical adaptability with programmable polar architectures. Especially, the photoalignment technology enables these polar states to be organized into pixelated domain architectures. This work establishes a design space towards soft ferroelectric polymers that integrate molecularly programmed polar order, mechanical tunability and environmentally conscious chemistry, expanding the design space of adaptive materials for flexible electronics, wearable systems and soft robotics.

cond-mat.soft

CS-MUNet: A Channel-Spatial Dual-Stream Mamba Network for Multi-Organ Segmentation

Recently Mamba-based methods have shown promise in abdominal organ segmentation. However, existing approaches neglect cross-channel anatomical semantic collaboration and lack explicit boundary-aware feature fusion mechanisms. To address these limitations, we propose CS-MUNet with two purpose-built modules. The Boundary-Aware State Mamba module employs a Bayesian-attention framework to generate pixel-level boundary posterior maps, injected directly into Mamba's core scan parameters to embed boundary awareness into the SSM state transition mechanism, while dual-branch weight allocation enables complementary modulation between global and local structural representations. The Channel Mamba State Aggregation module redefines the channel dimension as the SSM sequence dimension to explicitly model cross-channel anatomical semantic collaboration in a data-driven manner. Experiments on two public benchmarks demonstrate that CS-MUNet consistently outperforms state-of-the-art methods across multiple metrics, establishing a new SSM modeling paradigm that jointly addresses channel semantic collaboration and boundary-aware feature fusion for abdominal multi-organ segmentation.

cs.CV

Unified Multimodal Coherent Field: Synchronous Semantic-Spatial-Vision Fusion for Brain Tumor Segmentation

Brain tumor segmentation requires accurate identification of hierarchical regions including whole tumor (WT), tumor core (TC), and enhancing tumor (ET) from multi-sequence magnetic resonance imaging (MRI) images. Due to tumor tissue heterogeneity, ambiguous boundaries, and contrast variations across MRI sequences, methods relying solely on visual information or post-hoc loss constraints show unstable performance in boundary delineation and hierarchy preservation. To address this challenge, we propose the Unified Multimodal Coherent Field (UMCF) method. This method achieves synchronous interactive fusion of visual, semantic, and spatial information within a unified 3D latent space, adaptively adjusting modal contributions through parameter-free uncertainty gating, with medical prior knowledge directly participating in attention computation, avoiding the traditional "process-then-concatenate" separated architecture. On Brain Tumor Segmentation (BraTS) 2020 and 2021 datasets, UMCF+nnU-Net achieves average Dice coefficients of 0.8579 and 0.8977 respectively, with an average 4.18% improvement across mainstream architectures. By deeply integrating clinical knowledge with imaging features, UMCF provides a new technical pathway for multimodal information fusion in precision medicine.

cs.CV