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Zeeshan Ahmed

Publications and source records attributed to Zeeshan Ahmed.

At least 19 recordsLinked to original sources

Tracing the Heart: An Evidence-Linked Pipeline for Heart-Failure Feature Engineering

Electronic health record (EHR) feature engineering is a major bottleneck in clinical research and AI, accounting for 39-45% of data scientists' workload. This is especially pronounced in heart failure, which affects an estimated 6.7 million U.S. adults and requires integrating fragmented EHR data with disease-specific, guideline-based clinical reasoning. Existing rule-based and large language model (LLM)-based approaches offer only partial automation with limited maintainability and evidence traceability. We developed the Nimblemind Multi-Agent System (nMAS), an evidence-linked, rubric-grounded pipeline for automated heart-failure feature engineering, and evaluated it on 500 dummy patient records from nine EHR source tables. nMAS generated 132 structured and 70 rubric-scored aggregated features, verified for structural integrity, rubric compliance, and provenance, and audited by a restricted LLM. Adding the aggregated features improved held-out AUROC from 0.895 to 0.963 for HFrEF and 0.870 to 0.910 for HFpEF phenotyping, and an independent LLM-based rubric assessment of evidence support and methodological soundness scored the features at 81.5% of maximum points. These results demonstrate the feasibility of automated, auditable feature engineering for complex cardiovascular EHR data, though evaluation was limited to a single-institution cohort and external validation is needed.

cs.AI

A Kalman Filter Based Approach to NV Diamond Data Fusion For Improved Temperature Sensing

Nitrogen-vacancy (NV) centers in diamond have been demonstrated to enable highly sensitive temperature measurements using multiple modalities. Standalone optically detected magnetic resonance (ODMR) provides robust temperature estimates, albeit with high latency, whereas all-optical measurements provide millisecond resolution but suffer from poorer long-term accuracy. In this work, we demonstrate a hot-start Kalman filtering approach that fuses the two modalities, leading to a 57% improvement in accuracy. The fused estimate achieves higher long-term accuracy with lower latency, demonstrating a viable route toward implementing self-correcting, high-precision NV-diamond temperature sensing schemes.

physics.ins-det

Orthogonal Dendritic Intrinsic Networks: An Architecture for Significance-Ordered, Orthogonal Latent Spaces

Principal Component Analysis or PCA-like properties (orthogonality, variance ranking) are seldom realized in deep autoencoder architectures. In this work, we present ODIN (Orthogonal Dendritic Intrinsic Network), a novel autoencoder architecture that recovers PCA-like latent structure in a fully non-linear regime. By incorporating a set of geometric constraints directly into the training objective, ODIN encourages latent dimensions to be mutually orthogonal and ordered by explained variance, mirroring the interpretable decomposition of PCA while retaining the expressive power of deep networks. We provide theoretical grounding for these constraints and demonstrate their compatibility with standard encoder-decoder frameworks. We also establish empirical results for both synthetic and real world datasets, establishing a principled path toward interpretable, structured feature learning and dimensionality reduction.

cs.LG

BICEP/Keck XXI: Constraints on Early-Universe Parity Violation from Multipole-Dependent Birefringence

We present the first constraints on multipole-dependent cosmic birefringence using CMB polarization data from the BK18 dataset, which combines observations from BICEP2, Keck Array, and BICEP3 at frequencies of 95, 150, and 220 GHz. Photon coupling to an axion-like field leads to the rotation of CMB polarization, inducing non-zero EB cross-correlations. We show that a multipole-dependent rotation beta(l) imprints a distinct signature in the polarization spectra that can be constrained. Specifically, we consider an Early Dark Energy (EDE) scenario in which a pseudoscalar field couples to photons through a Chern-Simons interaction, generating a polarization rotation with multipole dependence. We introduce a phenomenological beta(l) as a step function, obtaining constraints on the step function size consistent with zero, with uncertainties less than 0.15 degrees (68% CL). In addition, using multi-frequency EE, BB, and EB cross-spectra, along with robust BICEP/Keck foreground treatment and likelihood framework, we derive constraints on the axion-photon coupling amplitude g for several choices of EDE parameters. For the baseline best-fit value f_{EDE} = 0.087 from the Planck 2018 analysis, we obtain g = 0.11 +/- 0.37 (68% CL), consistent with previous limits.

astro-ph.CO

Unified and consistent structure growth measurements from joint ACT, SPT and \textit{Planck} CMB lensing

We present the tightest cosmic microwave background (CMB) lensing constraints to date on the growth of structure by combining CMB lensing measurements from the Atacama Cosmology Telescope (ACT), the South Pole Telescope (SPT) and \textit{Planck}. Each of these surveys individually provides lensing measurements with similarly high statistical power, achieving signal-to-noise ratios of approximately 40. The combined lensing bandpowers represent the most precise CMB lensing power spectrum measurement to date with a signal-to-noise ratio of 61 and an amplitude of $A_\mathrm{lens}^\mathrm{recon} = 1.025 \pm 0.017$ with respect to the theory prediction from the best-fit CMB \textit{Planck}-ACT cosmology. The bandpowers from all three lensing datasets, analyzed jointly, yield a $1.6\%$ measurement of the parameter combination $S_8^\mathrm{CMBL} \equiv σ_8\,(Ω_m/0.3)^{0.25} = 0.825^{+0.015}_{-0.013}$. Including Dark Energy Spectroscopic Instrument (DESI) Baryon Acoustic Oscillation (BAO) data improves the constraint on the amplitude of matter fluctuations to $σ_8 = 0.829 \pm 0.009$ (a $1.1\%$ determination). When combining with uncalibrated supernovae from \texttt{Pantheon+}, we present a $4\%$ sound-horizon-independent estimate of $H_0=66.4\pm2.5\,\mathrm{km\,s^{-1}\,Mpc^{-1}} $. The joint lensing constraints on structure growth and present-day Hubble rate are fully consistent with a $Λ$CDM model fit to the primary CMB data from \textit{Planck} and ACT. While the precise upper limit is sensitive to the choice of data and underlying model assumptions, when varying the neutrino mass sum within the $Λ\mathrm{CDM}$ cosmological model, the combination of primary CMB, BAO and CMB lensing drives the probable upper limit for the mass sum towards lower values, comparable to the minimum mass prior required by neutrino oscillation experiments.

astro-ph.CO

The Squeezed Bispectrum from CHIME HI Emission and Planck CMB Lensing: Current Sensitivity and Forecasts

Line intensity mapping using atomic hydrogen (HI) has the potential to efficiently map large volumes of the universe if the signal can be successfully separated from overwhelmingly bright radio foreground emission. This motivates cross-correlations, to ascertain the cosmological nature of measured HI fluctuations, and to study their connections with galaxies and the underlying matter density field. However, these same foregrounds render the cross-correlation with projected fields such as the lensing of the cosmic microwave background (CMB) difficult. Indeed, the correlated Fourier modes vary slowly along the line of sight, and are thus most contaminated by the smooth-spectrum radio continuum foregrounds. In this paper, we implement a method that avoids this issue by attempting to measure the non-linear gravitational coupling of the small-scale 21cm power from the Canadian Hydrogen Intensity Mapping Experiment (CHIME) with large-scale Planck CMB lensing. This measurement is a position-dependent power spectrum, i.e. a squeezed integrated bispectrum. Using 94 nights of CHIME data between $1.0 < z < 1.3$ and aggressive foreground filtering, we find that the expected signal is five times smaller than the current noise. We forecast that incorporating the additional nights of CHIME data already collected would enable a signal-to-noise ratio of 3, without any further improvements in filtering for foreground cleaning.

astro-ph.CO

Thermal and Electrical Properties of Prototype Readout Components for CMB-S4

CMB-S4 is the fourth-generation ground-based cosmic microwave background project, designed to probe the early universe and cosmic inflation. CMB-S4 would achieve its science goals in part by dramatically increasing the number of transition edge sensor (TES) bolometer detectors on the sky. The detector readout system for CMB-S4 is time-division multiplexing (TDM) with a two-stage Superconducting Quantum Interference Device (SQUID) system. To accommodate the large increase in detectors, the size of our camera increases, placing physical constraints on the readout, its wiring, and its power dissipation. Therefore, to optimize readout performance, we need to balance competing design considerations such as thermal load and bandwidth. We present results characterizing the thermal and electrical performance of prototype components, including wiring and SQUID arrays for CMB-S4, and discuss the impact on overall system performance.

astro-ph.IM

The Simons Observatory: Studies of Phase Drift in RF Transmission Lines from the First Large-Scale Deployment of Microwave Frequency Multiplexing for Cosmology

Fulfilling the science goals of the Simons Observatory, a state-of-the-art cosmic microwave background (CMB) experiment, has required deploying tens of thousands of superconducting bolometers. Reading out data from the observatory's more than 67,000 transition-edge sensor (TES) detectors while maintaining cryogenic conditions requires an effective multiplexing scheme. The SLAC microresonator radio frequency (SMuRF) electronics have been developed to provide the warm electronics for a high-density microwave frequency multiplexing readout system, and this system has been shown to achieve multiplexing factors on the order of 1,000. SMuRF has recently been deployed to the Simons Observatory, which is located at 5,200 m on Cerro Toco in Chile's Atacama Desert. As the SMuRF system is exposed to the desert's diurnal temperature swings, resulting phase drift in RF transmission lines may introduce a systematic signal contamination. We present studies of phase drift in the room-temperature RF lines of the Simons Observatory's 6 m large-aperture telescope, which hosts the largest deployment to date of TES microwave frequency multiplexing to a single telescope. We show that these phase drifts occur on time scales which are significantly longer than sky scanning, and that their contribution to on-sky in-transition detector noise is within the readout noise budget.

astro-ph.IM

Simulating quantum collision models with Hamiltonian simulations using early fault-tolerant quantum computers

We develop randomized quantum algorithms to simulate quantum collision models, also known as repeated interaction schemes, which provide a rich framework to model various open-system dynamics. The underlying technique involves composing time evolutions of the total (system, bath, and interaction) Hamiltonian and intermittent tracing out of the environment degrees of freedom. This results in a unified framework where any near-term Hamiltonian simulation algorithm can be incorporated to implement an arbitrary number of such collisions on early fault-tolerant quantum computers: we do not assume access to specialized oracles such as block encodings and minimize the number of ancilla qubits needed. In particular, using the correspondence between Lindbladian evolution and completely positive trace-preserving maps arising out of memoryless collisions, we provide an end-to-end quantum algorithm for simulating Lindbladian dynamics. For a system of $n$-qubits, we exhaustively compare the circuit depth needed to estimate the expectation value of an observable with respect to the reduced state of the system after time $t$ while employing different near-term Hamiltonian simulation techniques, requiring at most $n+2$ qubits in all. We compare the CNOT gate counts of the various approaches for estimating the Transverse Field Magnetization of a $10$-qubit XX-Heisenberg spin chain under amplitude damping. Finally, we also develop a framework to efficiently simulate an arbitrary number of memory-retaining collisions, i.e., where environments interact, leading to non-Markovian dynamics. Overall, our methods can leverage quantum collision models for both Markovian and non-Markovian dynamics on early fault-tolerant quantum computers, shedding light on the advantages and limitations of simulating open systems dynamics using this framework.

quant-ph

Overcoming Latency Bottlenecks in On-Device Speech Translation: A Cascaded Approach with Alignment-Based Streaming MT

This paper tackles several challenges that arise when integrating Automatic Speech Recognition (ASR) and Machine Translation (MT) for real-time, on-device streaming speech translation. Although state-of-the-art ASR systems based on Recurrent Neural Network Transducers (RNN-T) can perform real-time transcription, achieving streaming translation in real-time remains a significant challenge. To address this issue, we propose a simultaneous translation approach that effectively balances translation quality and latency. We also investigate efficient integration of ASR and MT, leveraging linguistic cues generated by the ASR system to manage context and utilizing efficient beam-search pruning techniques such as time-out and forced finalization to maintain system's real-time factor. We apply our approach to an on-device bilingual conversational speech translation and demonstrate that our techniques outperform baselines in terms of latency and quality. Notably, our technique narrows the quality gap with non-streaming translation systems, paving the way for more accurate and efficient real-time speech translation.

cs.CL

Evaluating probabilistic and data-driven inference models for fiber-coupled NV-diamond temperature sensors

We evaluate the impact of inference model on uncertainties when using continuous wave Optically Detected Magnetic Resonance (ODMR) measurements to infer temperature. Our approach leverages a probabilistic feedforward inference model designed to maximize the likelihood of observed ODMR spectra through automatic differentiation. This model effectively utilizes the temperature dependence of spin Hamiltonian parameters to infer temperature from spectral features in the ODMR data. We achieve prediction uncertainty of $\pm$ 1 K across a temperature range of 243 K to 323 K. To benchmark our probabilistic model, we compare it with a non-parametric peak-finding technique and data-driven methodologies such as Principal Component Regression (PCR) and a 1D Convolutional Neural Network (CNN). We find that when validated against out-of-sample dataset that encompasses the same temperature range as the training dataset, data driven methods can show uncertainties that are as much as 0.67 K lower without incorporating expert-level understanding of the spectroscopic-temperature relationship. However, our results show that the probabilistic model outperforms both PCR and CNN when tasked with extrapolating beyond the temperature range used in training set, indicating robustness and generalizability. In contrast, data-driven methods like PCR and CNN demonstrate up to ten times worse uncertainties when tasked with extrapolating outside their training data range.

physics.ins-det

Non-Monotonic Attention-based Read/Write Policy Learning for Simultaneous Translation

Simultaneous or streaming machine translation generates translation while reading the input stream. These systems face a quality/latency trade-off, aiming to achieve high translation quality similar to non-streaming models with minimal latency. We propose an approach that efficiently manages this trade-off. By enhancing a pretrained non-streaming model, which was trained with a seq2seq mechanism and represents the upper bound in quality, we convert it into a streaming model by utilizing the alignment between source and target tokens. This alignment is used to learn a read/write decision boundary for reliable translation generation with minimal input. During training, the model learns the decision boundary through a read/write policy module, employing supervised learning on the alignment points (pseudo labels). The read/write policy module, a small binary classification unit, can control the quality/latency trade-off during inference. Experimental results show that our model outperforms several strong baselines and narrows the gap with the non-streaming baseline model.

cs.CL

CMB-S4: Foreground-Cleaning Pipeline Comparison for Measuring Primordial Gravitational Waves

We compare multiple foreground-cleaning pipelines for estimating the tensor-to-scalar ratio, $r$, using simulated maps of the planned CMB-S4 experiment within the context of the South Pole Deep Patch. To evaluate robustness, we analyze bias and uncertainty on $r$ across various foreground suites using map-based simulations. The foreground-cleaning methods include: a parametric maximum likelihood approach applied to auto- and cross-power spectra between frequency maps; a map-based parametric maximum-likelihood method; and a harmonic-space internal linear combination using frequency maps. We summarize the conceptual basis of each method to highlight their similarities and differences. To better probe the impact of foreground residuals, we implement an iterative internal delensing step, leveraging a map-based pipeline to generate a lensing $B$-mode template from the Large Aperture Telescope frequency maps. Our results show that the performance of the three approaches is comparable for simple and intermediate-complexity foregrounds, with $σ(r)$ ranging from 3 to 5 $\times 10^{-4}$. However, biases at the $1-2σ$ level appear when analyzing more complex forms of foreground emission. By extending the baseline pipelines to marginalize over foreground residuals, we demonstrate that contamination can be reduced to within statistical uncertainties, albeit with a pipeline-dependent impact on $σ(r)$, which translates to a detection significance between 2 and 4$σ$ for an input value of $r = 0.003$. These findings suggest varying levels of maturity among the tested pipelines, with the auto- and cross-spectra-based approach demonstrating the best stability and overall performance. Moreover, given the extremely low noise levels, mutual validation of independent foreground-cleaning pipelines is essential to ensure the robustness of any potential detection.

astro-ph.CO

Simons Observatory: Characterization of the Large Aperture Telescope Receiver

The Simons Observatory (SO) is a ground-based cosmic microwave background (CMB) survey experiment that currently consists of three 0.42m small-aperture telescopes (SATs) and one 6m large-aperture telescope (LAT), located at an elevation of 5200m in the Atacama Desert in Chile. At the LAT's focal plane, SO will install >62,000 transition-edge sensor detectors across 13 optics tubes (OTs) within the Large Aperture Telescope Receiver (LATR), the largest cryogenic camera ever built to observe the CMB. Here we report on the validation of the LATR in the laboratory and the subsequent dark testing and validation within the LAT. We show that the LATR meets cryogenic, optical, and detector specifications required for high-sensitivity measurements of the CMB. At the time of writing, the LATR is installed in the LAT with six OTs (corresponding to >31,000 detectors), and the LAT mirrors and remaining seven OTs are undergoing development.

astro-ph.IM

Transcribing and Translating, Fast and Slow: Joint Speech Translation and Recognition

We propose the joint speech translation and recognition (JSTAR) model that leverages the fast-slow cascaded encoder architecture for simultaneous end-to-end automatic speech recognition (ASR) and speech translation (ST). The model is transducer-based and uses a multi-objective training strategy that optimizes both ASR and ST objectives simultaneously. This allows JSTAR to produce high-quality streaming ASR and ST results. We apply JSTAR in a bilingual conversational speech setting with smart-glasses, where the model is also trained to distinguish speech from different directions corresponding to the wearer and a conversational partner. Different model pre-training strategies are studied to further improve results, including training of a transducer-based streaming machine translation (MT) model for the first time and applying it for parameter initialization of JSTAR. We demonstrate superior performances of JSTAR compared to a strong cascaded ST model in both BLEU scores and latency.

eess.AS

Textless Streaming Speech-to-Speech Translation using Semantic Speech Tokens

Cascaded speech-to-speech translation systems often suffer from the error accumulation problem and high latency, which is a result of cascaded modules whose inference delays accumulate. In this paper, we propose a transducer-based speech translation model that outputs discrete speech tokens in a low-latency streaming fashion. This approach eliminates the need for generating text output first, followed by machine translation (MT) and text-to-speech (TTS) systems. The produced speech tokens can be directly used to generate a speech signal with low latency by utilizing an acoustic language model (LM) to obtain acoustic tokens and an audio codec model to retrieve the waveform. Experimental results show that the proposed method outperforms other existing approaches and achieves state-of-the-art results for streaming translation in terms of BLEU, average latency, and BLASER 2.0 scores for multiple language pairs using the CVSS-C dataset as a benchmark.

eess.AS

Calibration Measurements of the BICEP3 and BICEP Array CMB Polarimeters from 2017 to 2024

The BICEP3 and BICEP Array polarimeters are small-aperture refracting telescopes located at the South Pole designed to measure primordial gravitational wave signatures in the Cosmic Microwave Background (CMB) polarization, predicted by inflation. Constraining the inflationary signal requires not only excellent sensitivity, but also careful control of instrumental systematics. Both instruments use antenna-coupled orthogonally polarized detector pairs, and the polarized sky signal is reconstructed by taking the difference in each detector pair. As a result, the differential response between detectors within a pair becomes an important systematic effect we must control. Additionally, mapping the intensity and polarization response in regions away from the main beam can inform how sidelobe levels affect CMB measurements. Extensive calibration measurements are taken in situ every austral summer for control of instrumental systematics and instrument characterisation. In this work, we detail the set of beam calibration measurements that we conduct on the BICEP receivers, from deep measurements of main beam response to polarized beam response and sidelobe mapping. We discuss the impact of these measurements for instrumental systematics studies and design choices for future CMB receivers.

astro-ph.CO

The Simons Observatory: Dark Characterization of the Large Aperture Telescope

The Simons Observatory (SO) is a cosmic microwave background experiment composed of three 0.42 m Small Aperture Telescopes (SATs) and one 6 m Large Aperture Telescope (LAT) in the Atacama Desert of Chile. The Large Aperture Telescope Receiver (LATR) was integrated into the LAT in August 2023; however, because mirrors were not yet installed, the LATR optical chain was capped at the 4K stage. In this dark configuration we are able to characterize many elements of the instrument without contributions from atmospheric noise. Here we show this noise is below the required upper limit and its features are well described with a simple noise model. Maps produced using this noise model have properties that are in good agreement with the white noise levels of our dark data. Additionally, we show that our nominal scan strategy has a minimal effect on the noise when compared to the noise when the telescope is stationary

astro-ph.IM