arXiv subjects

Zelin Li

Publications and source records attributed to Zelin Li.

At least 37 records · Page 2Linked to original sources

arXiv2026

CellINR: Implicitly Overcoming Photo-induced Artifacts in 4D Live Fluorescence Microscopy

4D live fluorescence microscopy is often compromised by prolonged high intensity illumination which induces photobleaching and phototoxic effects that generate photo-induced artifacts and severely impair image continuity and detail recovery. To address this challenge, we propose the CellINR framework, a case-specific optimization approach based on implicit neural representation. The method employs blind convolution and structure amplification strategies to map 3D spatial coordinates into the high frequency domain, enabling precise modeling and high-accuracy reconstruction of cellular structures while effectively distinguishing true signals from artifacts. Experimental results demonstrate that CellINR significantly outperforms existing techniques in artifact removal and restoration of structural continuity, and for the first time, a paired 4D live cell imaging dataset is provided for evaluating reconstruction performance, thereby offering a solid foundation for subsequent quantitative analyses and biological research. The code and dataset will be public.

eess.IV↗

arXiv2026

Recover Cell Tensor: Diffusion-Equivalent Tensor Completion for Fluorescence Microscopy Imaging

Fluorescence microscopy (FM) imaging is a fundamental technique for observing live cell division, one of the most essential processes in the cycle of life and death. Observing 3D live cells requires scanning through the cell volume while minimizing lethal phototoxicity. That limits acquisition time and results in sparsely sampled volumes with anisotropic resolution and high noise. Existing image restoration methods, primarily based on inverse problem modeling, assume known and stable degradation processes and struggle under such conditions, especially in the absence of high-quality reference volumes. In this paper, from a new perspective, we propose a novel tensor completion framework tailored to the nature of FM imaging, which inherently involves nonlinear signal degradation and incomplete observations. Specifically, FM imaging with equidistant Z-axis sampling is essentially a tensor completion task under a uniformly random sampling condition. On one hand, we derive the theoretical lower bound for exact cell tensor completion, validating the feasibility of accurately recovering 3D cell tensor. On the other hand, we reformulate the tensor completion problem as a mathematically equivalent score-based generative model. By incorporating structural consistency priors, the generative trajectory is effectively guided toward denoised and geometrically coherent reconstructions. Our method demonstrates state-of-the-art performance on SR-CACO-2 and three real \textit{in vivo} cellular datasets, showing substantial improvements in both signal-to-noise ratio and structural fidelity.

eess.IV↗

arXiv2026

Mind the Ambiguity: Aleatoric Uncertainty Quantification in LLMs for Safe Medical Question Answering

The deployment of Large Language Models in Medical Question Answering is severely hampered by ambiguous user queries, a significant safety risk that demonstrably reduces answer accuracy in high-stakes healthcare settings. In this paper, we formalize this challenge by linking input ambiguity to aleatoric uncertainty (AU), which is the irreducible uncertainty arising from underspecified input. To facilitate research in this direction, we construct CV-MedBench, the first benchmark designed for studying input ambiguity in Medical QA. Using this benchmark, we analyze AU from a representation engineering perspective, revealing that AU is linearly encoded in LLM's internal activation patterns. Leveraging this insight, we introduce a novel AU-guided "Clarify-Before-Answer" framework, which incorporates AU-Probe - a lightweight module that detects input ambiguity directly from hidden states. Unlike existing uncertainty estimation methods, AU-Probe requires neither LLM fine-tuning nor multiple forward passes, enabling an efficient mechanism to proactively request user clarification and significantly enhance safety. Extensive experiments across four open LLMs demonstrate the effectiveness of our QA framework, with an average accuracy improvement of 9.48% over baselines. Our framework provides an efficient and robust solution for safe Medical QA, strengthening the reliability of health-related applications. The code is available at https://github.com/yaokunliu/AU-Med.git, and the CV-MedBench dataset is released on Hugging Face at https://huggingface.co/datasets/yaokunl/CV-MedBench.

cs.CL↗

arXiv2026

VeriLLM: A Lightweight Framework for Publicly Verifiable Decentralized Inference

Decentralized inference provides a scalable and resilient paradigm for serving large language models (LLMs), enabling fragmented global resource utilization and reducing reliance on centralized providers. However, in a permissionless environment without trusted nodes, ensuring the correctness of model outputs remains a core challenge. We introduce VeriLLM, a publicly verifiable protocol for decentralized LLM inference that achieves security with incentive guarantees while maintaining practical efficiency. VeriLLM combines lightweight empirical rerunning with minimal on-chain checks to preclude free-riding, allowing verifiers to validate results at approximately 1% of the underlying inference cost by exploiting the structural separation between prefill and autoregressive decoding. To prevent verification bottlenecks, we design an isomorphic inference--verification architecture that multiplexes both inference and verification roles across the same GPU workers. This design (i) improves GPU utilization and overall throughput, (ii) enlarges the effective validator set, enhancing robustness and liveness, and (iii) enforces task indistinguishability to prevent node-specific optimizations or selective behavior. Through theoretical analysis and system-level evaluation, we show that VeriLLM achieves reliable public verifiability with minimal overhead, offering a practical foundation for trustworthy and scalable decentralized LLM inference.

cs.CR↗

arXiv2026

MASH: A Multiplatform and Multimodal Annotated Dataset for Societal Impact of Hurricane

Natural disasters cause multidimensional threats to human societies, with hurricanes exemplifying one of the most disruptive events that not only caused severe physical damage but also sparked widespread discussion on social media platforms. Existing datasets for studying societal impacts of hurricanes often focus on outdated hurricanes and are limited to a single social media platform, failing to capture the broader societal impact in today's diverse social media environment. Moreover, existing datasets annotate visual and textual content of the post separately, failing to account for the multimodal nature of social media posts. To address these gaps, we present a multiplatform and Multimodal Annotated Dataset for Societal Impact of Hurricane (MASH) that includes 59,607 relevant social media data posts from Reddit, TikTok, and YouTube. In addition, all relevant social media data posts are annotated in a multimodal approach that considers both textual and visual content on three dimensions: Humanitarian Classes, Bias Classes, and Information Integrity Classes. To our best knowledge, MASH is the first large-scale, multi-platform, multimodal, and multi-dimensionally annotated dataset centered on hurricane disasters. In addition, we introduce an online platform that supports interactive data exploration, provides preliminary analytical results, and allows users to share their insights regarding the societal impacts of hurricanes. We envision that MASH can contribute to the study of hurricanes' impact on society, such as disaster response, disaster severity classification, public sentiment analysis, disaster policy making, and bias identification. The dataset is publicly available at https://huggingface.co/datasets/YRC10/MASH under the Creative Commons Attribution 4.0 (CC BY 4.0) license.

cs.SI↗

arXiv2026

Representing Sounds as Neural Amplitude Fields: A Benchmark of Coordinate-MLPs and A Fourier Kolmogorov-Arnold Framework

Although Coordinate-MLP-based implicit neural representations have excelled in representing radiance fields, 3D shapes, and images, their application to audio signals remains underexplored. To fill this gap, we investigate existing implicit neural representations, from which we extract 3 types of positional encoding and 16 commonly used activation functions. Through combinatorial design, we establish the first benchmark for Coordinate-MLPs in audio signal representations. Our benchmark reveals that Coordinate-MLPs require complex hyperparameter tuning and frequency-dependent initialization, limiting their robustness. To address these issues, we propose Fourier-ASR, a novel framework based on the Fourier series theorem and the Kolmogorov-Arnold representation theorem. Fourier-ASR introduces Fourier Kolmogorov-Arnold Networks (Fourier-KAN), which leverage periodicity and strong nonlinearity to represent audio signals, eliminating the need for additional positional encoding. Furthermore, a Frequency-adaptive Learning Strategy (FaLS) is proposed to enhance the convergence of Fourier-KAN by capturing high-frequency components and preventing overfitting of low-frequency signals. Extensive experiments conducted on natural speech and music datasets reveal that: (1) well-designed positional encoding and activation functions in Coordinate-MLPs can effectively improve audio representation quality; and (2) Fourier-ASR can robustly represent complex audio signals without extensive hyperparameter tuning. Looking ahead, the continuity and infinite resolution of implicit audio representations make our research highly promising for tasks such as audio compression, synthesis, and generation. The source code will be released publicly to ensure reproducibility. The code is available at https://github.com/lif314/Fourier-ASR.

cs.SD↗

arXiv2025

CTransformer: Deep-transformer-based 3D cell membrane tracking with subcellular-resolved molecular quantification

Deep learning segmentation and fluorescence imaging techniques allow the cellular morphology of living embryos to be constructed spatiotemporally. These development processes involve numerous molecules distributed at the subcellular scale, such as cell adhesion (E-cadherin), which accumulate at cell-cell interfaces to regulate intercellular connection. However, quantifying molecular distributions within specific subcellular regions across the entire embryo, where cell movement and molecular redistribution occur rapidly, is challenging due to the need for simultaneous cell morphology reconstruction and lineage tracing due to photobleaching and phototoxicity. We report a transformer-based pipeline, CTransformer, that establishes a 4D cellular morphology map before the 550-cell (late) stage. CTransformer constructed 4D cellular morphology atlases, reaching 80% accuracy at the 550-cell stage. Through this advanced architecture, we use only one channel to reconstruct cell morphology and achieve cell tracing. With each cell's morphology as a reference, the distribution of specific molecules throughout the cell body and at cell interfaces can be quantitatively measured in another fluorescence channel. We apply this methodology to track E-cadherin during embryonic development of the worm Caenorhabditis elegans, from fertilization to gastrulation. Our results reveal that E-cadherin is tightly regulated across individual embryos, both within single cells and at cell-cell interfaces, displaying an anterior-posterior gradient and cell- and lineage-specific patterns. Furthermore, its spatiotemporal heterogeneity influences cell mechanics and embryonic morphogenesis, helping explain how C. elegans achieves stereotypical developmental patterns at cellular resolution.

physics.bio-ph↗

arXiv2025

COMPARE: Clinical Optimization with Modular Planning and Assessment via RAG-Enhanced AI-OCT: Superior Decision Support for Percutaneous Coronary Intervention Compared to ChatGPT-5 and Junior Operators

Background: While intravascular imaging, particularly optical coherence tomography (OCT), improves percutaneous coronary intervention (PCI) outcomes, its interpretation is operator-dependent. General-purpose artificial intelligence (AI) shows promise but lacks domain-specific reliability. We evaluated the performance of CA-GPT, a novel large model deployed on an AI-OCT system, against that of the general-purpose ChatGPT-5 and junior physicians for OCT-guided PCI planning and assessment. Methods: In this single-center analysis of 96 patients who underwent OCT-guided PCI, the procedural decisions generated by the CA-GPT, ChatGPT-5, and junior physicians were compared with an expert-derived procedural record. Agreement was assessed using ten pre-specified metrics across pre-PCI and post-PCI phases. Results: For pre-PCI planning, CA-GPT demonstrated significantly higher median agreement scores (5[IQR 3.75-5]) compared to both ChatGPT-5 (3[2-4], P<0.001) and junior physicians (4[3-4], P<0.001). CA-GPT significantly outperformed ChatGPT-5 across all individual pre-PCI metrics and showed superior performance to junior physicians in stent diameter (90.3% vs. 72.2%, P<0.05) and length selection (80.6% vs. 52.8%, P<0.01). In post-PCI assessment, CA-GPT maintained excellent overall agreement (5[4.75-5]), significantly higher than both ChatGPT-5 (4[4-5], P<0.001) and junior physicians (5[4-5], P<0.05). Subgroup analysis confirmed CA-GPT's robust performance advantage in complex scenarios. Conclusion: The CA-GPT-based AI-OCT system achieved superior decision-making agreement versus a general-purpose large language model and junior physicians across both PCI planning and assessment phases. This approach provides a standardized and reliable method for intravascular imaging interpretation, demonstrating significant potential to augment operator expertise and optimize OCT-guided PCI.

cs.AI↗

arXiv2025

Sublinear-Time Algorithms for Diagonally Dominant Systems and Applications to the Friedkin-Johnsen Model

We study sublinear-time algorithms for solving linear systems $Sz = b$, where $S$ is a diagonally dominant matrix, i.e., $|S_{ii}| \geq δ+ \sum_{j \ne i} |S_{ij}|$ for all $i \in [n]$, for some $δ\geq 0$. We present randomized algorithms that, for any $u \in [n]$, return an estimate $z_u$ of $z^*_u$ with additive error $\varepsilon$ or $\varepsilon \lVert z^*\rVert_\infty$, where $z^*$ is some solution to $Sz^* = b$, and the algorithm only needs to read a small portion of the input $S$ and $b$. For example, when the additive error is $\varepsilon$ and assuming $δ>0$, we give an algorithm that runs in time $O\left( \frac{\|b\|_\infty^2 S_{\max}}{δ^3 \varepsilon^2} \log \frac{\| b \|_\infty}{δ\varepsilon} \right)$, where $S_{\max} = \max_{i \in [n]} |S_{ii}|$. We also prove a matching lower bound, showing that the linear dependence on $S_{\max}$ is optimal. Unlike previous sublinear-time algorithms, which apply only to symmetric diagonally dominant matrices with non-negative diagonal entries, our algorithm works for general strictly diagonally dominant matrices ($δ> 0$) and a broader class of non-strictly diagonally dominant matrices $(δ= 0)$. Our approach is based on analyzing a simple probabilistic recurrence satisfied by the solution. As an application, we obtain an improved sublinear-time algorithm for opinion estimation in the Friedkin--Johnsen model.

cs.DS↗

arXiv2025

LLMEval-Med: A Real-world Clinical Benchmark for Medical LLMs with Physician Validation

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and specialized assessments. However, these benchmarks have limitations in question design (mostly multiple-choice), data sources (often not derived from real clinical scenarios), and evaluation methods (poor assessment of complex reasoning). To address these issues, we present LLMEval-Med, a new benchmark covering five core medical areas, including 2,996 questions created from real-world electronic health records and expert-designed clinical scenarios. We also design an automated evaluation pipeline, incorporating expert-developed checklists into our LLM-as-Judge framework. Furthermore, our methodology validates machine scoring through human-machine agreement analysis, dynamically refining checklists and prompts based on expert feedback to ensure reliability. We evaluate 13 LLMs across three categories (specialized medical models, open-source models, and closed-source models) on LLMEval-Med, providing valuable insights for the safe and effective deployment of LLMs in medical domains. The dataset is released in https://github.com/llmeval/LLMEval-Med.

cs.CL↗

arXiv2025

Anti-Tamper Protection for Unauthorized Individual Image Generation

With the advancement of personalized image generation technologies, concerns about forgery attacks that infringe on portrait rights and privacy are growing. To address these concerns, protection perturbation algorithms have been developed to disrupt forgery generation. However, the protection algorithms would become ineffective when forgery attackers apply purification techniques to bypass the protection. To address this issue, we present a novel approach, Anti-Tamper Perturbation (ATP). ATP introduces a tamper-proof mechanism within the perturbation. It consists of protection and authorization perturbations, where the protection perturbation defends against forgery attacks, while the authorization perturbation detects purification-based tampering. Both protection and authorization perturbations are applied in the frequency domain under the guidance of a mask, ensuring that the protection perturbation does not disrupt the authorization perturbation. This design also enables the authorization perturbation to be distributed across all image pixels, preserving its sensitivity to purification-based tampering. ATP demonstrates its effectiveness in defending forgery attacks across various attack settings through extensive experiments, providing a robust solution for protecting individuals' portrait rights and privacy. Our code is available at: https://github.com/Seeyn/Anti-Tamper-Perturbation .

cs.CR↗

arXiv2025

Component-Based Fairness in Face Attribute Classification with Bayesian Network-informed Meta Learning

The widespread integration of face recognition technologies into various applications (e.g., access control and personalized advertising) necessitates a critical emphasis on fairness. While previous efforts have focused on demographic fairness, the fairness of individual biological face components remains unexplored. In this paper, we focus on face component fairness, a fairness notion defined by biological face features. To our best knowledge, our work is the first work to mitigate bias of face attribute prediction at the biological feature level. In this work, we identify two key challenges in optimizing face component fairness: attribute label scarcity and attribute inter-dependencies, both of which limit the effectiveness of bias mitigation from previous approaches. To address these issues, we propose \textbf{B}ayesian \textbf{N}etwork-informed \textbf{M}eta \textbf{R}eweighting (BNMR), which incorporates a Bayesian Network calibrator to guide an adaptive meta-learning-based sample reweighting process. During the training process of our approach, the Bayesian Network calibrator dynamically tracks model bias and encodes prior probabilities for face component attributes to overcome the above challenges. To demonstrate the efficacy of our approach, we conduct extensive experiments on a large-scale real-world human face dataset. Our results show that BNMR is able to consistently outperform recent face bias mitigation baselines. Moreover, our results suggest a positive impact of face component fairness on the commonly considered demographic fairness (e.g., \textit{gender}). Our findings pave the way for new research avenues on face component fairness, suggesting that face component fairness could serve as a potential surrogate objective for demographic fairness. The code for our work is publicly available~\footnote{https://github.com/yliuaa/BNMR-FairCompFace.git}.

cs.CV↗

arXiv2025

Volume Tells: Dual Cycle-Consistent Diffusion for 3D Fluorescence Microscopy De-noising and Super-Resolution

3D fluorescence microscopy is essential for understanding fundamental life processes through long-term live-cell imaging. However, due to inherent issues in imaging principles, it faces significant challenges including spatially varying noise and anisotropic resolution, where the axial resolution lags behind the lateral resolution up to 4.5 times. Meanwhile, laser power is kept low to maintain cell viability, leading to inaccessible low-noise and high-resolution paired ground truth (GT). To tackle these limitations, a dual Cycle-consistent Diffusion is proposed to effectively mine intra-volume imaging priors within 3D cell volumes in an unsupervised manner, i.e., Volume Tells (VTCD), achieving de-noising and super-resolution (SR) simultaneously. Specifically, a spatially iso-distributed denoiser is designed to exploit the noise distribution consistency between adjacent low-noise and high-noise regions within the 3D cell volume, suppressing the spatially varying noise. Then, in light of the structural consistency of the cell volume, a cross-plane global-propagation SR module propagates high-resolution details from the XY plane into adjacent regions in the XZ and YZ planes, progressively enhancing resolution across the entire 3D cell volume. Experimental results on 10 in vivo cellular dataset demonstrate high improvements in both denoising and super-resolution, with axial resolution enhanced from ~ 430 nm to ~ 90 nm.

eess.IV↗

arXiv2025

Modality Interactive Mixture-of-Experts for Fake News Detection

The proliferation of fake news on social media platforms disproportionately impacts vulnerable populations, eroding trust, exacerbating inequality, and amplifying harmful narratives. Detecting fake news in multimodal contexts -- where deceptive content combines text and images -- is particularly challenging due to the nuanced interplay between modalities. Existing multimodal fake news detection methods often emphasize cross-modal consistency but ignore the complex interactions between text and visual elements, which may complement, contradict, or independently influence the predicted veracity of a post. To address these challenges, we present Modality Interactive Mixture-of-Experts for Fake News Detection (MIMoE-FND), a novel hierarchical Mixture-of-Experts framework designed to enhance multimodal fake news detection by explicitly modeling modality interactions through an interaction gating mechanism. Our approach models modality interactions by evaluating two key aspects of modality interactions: unimodal prediction agreement and semantic alignment. The hierarchical structure of MIMoE-FND allows for distinct learning pathways tailored to different fusion scenarios, adapting to the unique characteristics of each modality interaction. By tailoring fusion strategies to diverse modality interaction scenarios, MIMoE-FND provides a more robust and nuanced approach to multimodal fake news detection. We evaluate our approach on three real-world benchmarks spanning two languages, demonstrating its superior performance compared to state-of-the-art methods. By enhancing the accuracy and interpretability of fake news detection, MIMoE-FND offers a promising tool to mitigate the spread of misinformation, with the potential to better safeguard vulnerable communities against its harmful effects.

cs.LG↗

arXiv2024

TF-Attack: Transferable and Fast Adversarial Attacks on Large Language Models

With the great advancements in large language models (LLMs), adversarial attacks against LLMs have recently attracted increasing attention. We found that pre-existing adversarial attack methodologies exhibit limited transferability and are notably inefficient, particularly when applied to LLMs. In this paper, we analyze the core mechanisms of previous predominant adversarial attack methods, revealing that 1) the distributions of importance score differ markedly among victim models, restricting the transferability; 2) the sequential attack processes induces substantial time overheads. Based on the above two insights, we introduce a new scheme, named TF-Attack, for Transferable and Fast adversarial attacks on LLMs. TF-Attack employs an external LLM as a third-party overseer rather than the victim model to identify critical units within sentences. Moreover, TF-Attack introduces the concept of Importance Level, which allows for parallel substitutions of attacks. We conduct extensive experiments on 6 widely adopted benchmarks, evaluating the proposed method through both automatic and human metrics. Results show that our method consistently surpasses previous methods in transferability and delivers significant speed improvements, up to 20 times faster than earlier attack strategies.

cs.CL↗

arXiv2023

Source Free Unsupervised Graph Domain Adaptation

Graph Neural Networks (GNNs) have achieved great success on a variety of tasks with graph-structural data, among which node classification is an essential one. Unsupervised Graph Domain Adaptation (UGDA) shows its practical value of reducing the labeling cost for node classification. It leverages knowledge from a labeled graph (i.e., source domain) to tackle the same task on another unlabeled graph (i.e., target domain). Most existing UGDA methods heavily rely on the labeled graph in the source domain. They utilize labels from the source domain as the supervision signal and are jointly trained on both the source graph and the target graph. However, in some real-world scenarios, the source graph is inaccessible because of privacy issues. Therefore, we propose a novel scenario named Source Free Unsupervised Graph Domain Adaptation (SFUGDA). In this scenario, the only information we can leverage from the source domain is the well-trained source model, without any exposure to the source graph and its labels. As a result, existing UGDA methods are not feasible anymore. To address the non-trivial adaptation challenges in this practical scenario, we propose a model-agnostic algorithm called SOGA for domain adaptation to fully exploit the discriminative ability of the source model while preserving the consistency of structural proximity on the target graph. We prove the effectiveness of the proposed algorithm both theoretically and empirically. The experimental results on four cross-domain tasks show consistent improvements in the Macro-F1 score and Macro-AUC.

cs.LG↗

arXiv2023

Massively Parallel Algorithms for the Stochastic Block Model

Learning the community structure of a large-scale graph is a fundamental problem in machine learning, computer science and statistics. We study the problem of exactly recovering the communities in a graph generated from the Stochastic Block Model (SBM) in the Massively Parallel Computation (MPC) model. Specifically, given $kn$ vertices that are partitioned into $k$ equal-sized clusters (i.e., each has size $n$), a graph on these $kn$ vertices is randomly generated such that each pair of vertices is connected with probability~$p$ if they are in the same cluster and with probability $q$ if not, where $p > q > 0$. We give MPC algorithms for the SBM in the (very general) \emph{$s$-space MPC model}, where each machine has memory $s=Ω(\log n)$. Under the condition that $\frac{p-q}{\sqrt{p}}\geq \tildeΩ(k^{\frac12}n^{-\frac12+\frac{1}{2(r-1)}})$ for any integer $r\in [3,O(\log n)]$, our first algorithm exactly recovers all the $k$ clusters in $O(kr\log_s n)$ rounds using $\tilde{O}(m)$ total space, or in $O(r\log_s n)$ rounds using $\tilde{O}(km)$ total space. If $\frac{p-q}{\sqrt{p}}\geq \tildeΩ(k^{\frac34}n^{-\frac14})$, our second algorithm achieves $O(\log_s n)$ rounds and $\tilde{O}(m)$ total space complexity. Both algorithms significantly improve upon a recent result of Cohen-Addad et al. [PODC'22], who gave algorithms that only work in the \emph{sublinear space MPC model}, where each machine has local memory~$s=O(n^δ)$ for some constant $δ>0$, with a much stronger condition on $p,q,k$. Our algorithms are based on collecting the $r$-step neighborhood of each vertex and comparing the difference of some statistical information generated from the local neighborhoods for each pair of vertices. To implement the clustering algorithms in parallel, we present efficient approaches for implementing some basic graph operations in the $s$-space MPC model.

cs.DS↗

arXiv2023

The `blazar sequence' in TeV band

The `blazar sequence' has been proposed for more than 20 years, yet its nature is still unclear. In this work, for the first time, we expand this topic to the TeV band by using a sample of 58 TeV blazars including 48 blazars in the quiescent state and 21 blazars in the flaring state. We investigate the correlation between the TeV luminosity, which has been compensated for attenuation from extragalactic background light, and the synchrotron peak frequency. We note that there is no correlation between TeV luminosity and peak frequency in the quiescent state and a strong anti-correlation in the flaring state for the observed value. However, there is a strong positive correlation in both the quiescent state and the flaring state for the intrinsic value. This indicates that the blazar sequence is shown in the flaring state rather than in the quiescent state for the observed value and the blazar sequence is not present in both two states after removing the beaming effect. In addition, to confirm whether the beaming effect results in the blazar sequence, we compare the \textit{Fermi} $γ$-ray luminosity between the quiescent state and the flaring state. We find the \textit{Fermi} $γ$-ray luminosity in the flaring state is greater than that in the quiescent state and the Doppler factor in the flaring state is greater. We suggest the blazar sequence in the flaring state may be due to the stronger beaming effect.

astro-ph.HE↗