arXiv subjects

Zhaohong Deng

Publications and source records attributed to Zhaohong Deng.

At least 19 recordsLinked to original sources

arXiv2026

Multi-Modal Generative Fuzzy System: Fuzzy Inference Guided Large Model Interactive Question Answering Framework

In Multimodal Question Answering (MQA), models are required to jointly encode and integrate heterogeneous information from multiple modalities, including text, images, and speech, to perform complex semantic reasoning and decision making. Despite recent advances, existing approaches, including traditional deep learning models and Large Models (LMs) or prompt-based frameworks, continue to face several critical challenges. First, modality bias arises from discrepancies in feature distributions across different modalities, which limits effective cross modal collaborative understanding. Second, many questions require knowledge drawn from multiple domains, introducing significant uncertainty. Third, current methods often rely on shallow semantic matching, resulting in limited reasoning depth an reduced interpretability. To address these issues, inspired by the traditional fuzzy system (FS) framework, we propose a fuzzy-inference-guided multimodal generative architecture termed the Multi-Modal Generative Fuzzy System (MMGFS). The main contributions of MMGFS are two folds. First, it alleviates modality bias through a multimodal collaborative rumination mechanism. Second, it introduces fuzzy rules and a multi-hop inference mechanism to support cross-domain knowledge fusion and hierarchical reasoning, thereby strengthening uncertainty modelling and deepening semantic understanding. We conduct comprehensive evaluations on open-domain question answering datasets, including MultimodalQA and WebQA, as well as domain-specific benchmarks, including BioMol-VQA and EHRxQA. Experimental results demonstrate that MMGFS consistently outperforms existing methods across multiple datasets. It effectively mitigates modality bias and question uncertainty while achieving superior performance in answer accuracy, consistency, and generalization.

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arXiv2026

A Novel TSK Fuzzy System Incorporating Multi-view Collaborative Transfer Learning for Personalized Epileptic EEG Detection

In clinical practice, electroencephalography (EEG) plays an important role in the diagnosis of epilepsy. EEG-based computer-aided diagnosis of epilepsy can greatly improve the ac-curacy of epilepsy detection while reducing the workload of physicians. However, there are many challenges in practical applications for personalized epileptic EEG detection (i.e., training of detection model for a specific person), including the difficulty in extracting effective features from one single view, the undesirable but common scenario of lacking sufficient training data in practice, and the no guarantee of identically distributed training and test data. To solve these problems, we propose a TSK fuzzy system-based epilepsy detection algorithm that integrates multi-view collaborative transfer learning. To address the challenge due to the limitation of single-view features, multi-view learning ensures the diversity of features by extracting them from different views. The lack of training data for building a personalized detection model is tackled by leveraging the knowledge from the source domain (reference scene) to enhance the performance of the target domain (current scene of interest), where mismatch of data distributions between the two domains is resolved with adaption technique based on maximum mean discrepancy. Notably, the transfer learning and multi-view feature extraction are performed at the same time. Furthermore, the fuzzy rules of the TSK fuzzy system equip the model with strong fuzzy logic inference capability. Hence, the proposed method has the potential to detect epileptic EEG signals effectively, which is demonstrated with the positive results from a large number of experiments on the CHB-MIT dataset.

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arXiv2025

Diffusion Fuzzy System: Fuzzy Rule Guided Latent Multi-Path Diffusion Modeling

Diffusion models have emerged as a leading technique for generating images due to their ability to create high-resolution and realistic images. Despite their strong performance, diffusion models still struggle in managing image collections with significant feature differences. They often fail to capture complex features and produce conflicting results. Research has attempted to address this issue by learning different regions of an image through multiple diffusion paths and then combining them. However, this approach leads to inefficient coordination among multiple paths and high computational costs. To tackle these issues, this paper presents a Diffusion Fuzzy System (DFS), a latent-space multi-path diffusion model guided by fuzzy rules. DFS offers several advantages. First, unlike traditional multi-path diffusion methods, DFS uses multiple diffusion paths, each dedicated to learning a specific class of image features. By assigning each path to a different feature type, DFS overcomes the limitations of multi-path models in capturing heterogeneous image features. Second, DFS employs rule-chain-based reasoning to dynamically steer the diffusion process and enable efficient coordination among multiple paths. Finally, DFS introduces a fuzzy membership-based latent-space compression mechanism to reduce the computational costs of multi-path diffusion effectively. We tested our method on three public datasets: LSUN Bedroom, LSUN Church, and MS COCO. The results show that DFS achieves more stable training and faster convergence than existing single-path and multi-path diffusion models. Additionally, DFS surpasses baseline models in both image quality and alignment between text and images, and also shows improved accuracy when comparing generated images to target references.

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arXiv2025

GAMA: A General Anonymizing Multi-Agent System for Privacy Preservation Enhanced by Domain Rules and Disproof Mechanism

With the rapid advancement of Large Language Models (LLMs), LLM-based agents exhibit exceptional abilities in understanding and generating natural language, enabling human-like collaboration and information transmission in LLM-based Multi-Agent Systems (MAS). High-performance LLMs are often hosted on web servers in public cloud environments. When tasks involve private data, MAS cannot securely utilize these LLMs without implementing the agentic privacy-preserving mechanism. To address this challenge, we propose a General Anonymizing Multi-Agent System (GAMA), which divides the agents' workspace into private and public spaces, ensuring privacy through a structured anonymization mechanism. In the private space, agents handle sensitive data, while in the public web space, only anonymized data is utilized. GAMA incorporates two key modules to mitigate semantic loss caused by anonymization: Domain-Rule-based Knowledge Enhancement (DRKE) and Disproof-based Logic Enhancement (DLE). We evaluate GAMA on two general question-answering datasets, a public privacy leakage benchmark, and two customized question-answering datasets related to privacy. The results demonstrate that GAMA outperforms existing baselines on the evaluated datasets in terms of both task accuracy and privacy preservation metrics.

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arXiv2025

XAgents: A Framework for Interpretable Rule-Based Multi-Agents Cooperation

Extracting implicit knowledge and logical reasoning abilities from large language models (LLMs) has consistently been a significant challenge. The advancement of multi-agent systems has further en-hanced the capabilities of LLMs. Inspired by the structure of multi-polar neurons (MNs), we propose the XAgents framework, an in-terpretable multi-agent cooperative framework based on the IF-THEN rule-based system. The IF-Parts of the rules are responsible for logical reasoning and domain membership calculation, while the THEN-Parts are comprised of domain expert agents that generate domain-specific contents. Following the calculation of the member-ship, XAgetns transmits the task to the disparate domain rules, which subsequently generate the various responses. These re-sponses are analogous to the answers provided by different experts to the same question. The final response is reached at by eliminat-ing the hallucinations and erroneous knowledge of the LLM through membership computation and semantic adversarial genera-tion of the various domain rules. The incorporation of rule-based interpretability serves to bolster user confidence in the XAgents framework. We evaluate the efficacy of XAgents through a com-parative analysis with the latest AutoAgents, in which XAgents demonstrated superior performance across three distinct datasets. We perform post-hoc interpretable studies with SHAP algorithm and case studies, proving the interpretability of XAgent in terms of input-output feature correlation and rule-based semantics.

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arXiv2025

XAgents: A Unified Framework for Multi-Agent Cooperation via IF-THEN Rules and Multipolar Task Processing Graph

The rapid advancement of Large Language Models (LLMs) has significantly enhanced the capabilities of Multi-Agent Systems (MAS) in supporting humans with complex, real-world tasks. However, MAS still face challenges in effective task planning when handling highly complex tasks with uncertainty, often resulting in misleading or incorrect outputs that hinder task execution. To address this, we propose XAgents, a unified multi-agent cooperative framework built on a multipolar task processing graph and IF-THEN rules. XAgents uses the multipolar task processing graph to enable dynamic task planning and handle task uncertainty. During subtask processing, it integrates domain-specific IF-THEN rules to constrain agent behaviors, while global rules enhance inter-agent collaboration. We evaluate the performance of XAgents across three distinct datasets, demonstrating that it consistently surpasses state-of-the-art single-agent and multi-agent approaches in both knowledge-typed and logic-typed question-answering tasks. The codes for XAgents are available at: https://github.com/AGI-FHBC/XAgents.

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arXiv2025

Modeling enzyme temperature stability from sequence segment perspective

Developing enzymes with desired thermal properties is crucial for a wide range of industrial and research applications, and determining temperature stability is an essential step in this process. Experimental determination of thermal parameters is labor-intensive, time-consuming, and costly. Moreover, existing computational approaches are often hindered by limited data availability and imbalanced distributions. To address these challenges, we introduce a curated temperature stability dataset designed for model development and benchmarking in enzyme thermal modeling. Leveraging this dataset, we present the \textit{Segment Transformer}, a novel deep learning framework that enables efficient and accurate prediction of enzyme temperature stability. The model achieves state-of-the-art performance with an RMSE of 24.03, MAE of 18.09, and Pearson and Spearman correlations of 0.33, respectively. These results highlight the effectiveness of incorporating segment-level representations, grounded in the biological observation that different regions of a protein sequence contribute unequally to thermal behavior. As a proof of concept, we applied the Segment Transformer to guide the engineering of a cutinase enzyme. Experimental validation demonstrated a 1.64-fold improvement in relative activity following heat treatment, achieved through only 17 mutations and without compromising catalytic function.

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arXiv2025

DRIMV_TSK: An Interpretable Surgical Evaluation Model for Incomplete Multi-View Rectal Cancer Data

A reliable evaluation of surgical difficulty can improve the success of the treatment for rectal cancer and the current evaluation method is based on clinical data. However, more data about rectal cancer can be collected with the development of technology. Meanwhile, with the development of artificial intelligence, its application in rectal cancer treatment is becoming possible. In this paper, a multi-view rectal cancer dataset is first constructed to give a more comprehensive view of patients, including the high-resolution MRI image view, pressed-fat MRI image view, and clinical data view. Then, an interpretable incomplete multi-view surgical evaluation model is proposed, considering that it is hard to obtain extensive and complete patient data in real application scenarios. Specifically, a dual representation incomplete multi-view learning model is first proposed to extract the common information between views and specific information in each view. In this model, the missing view imputation is integrated into representation learning, and second-order similarity constraint is also introduced to improve the cooperative learning between these two parts. Then, based on the imputed multi-view data and the learned dual representation, a multi-view surgical evaluation model with the TSK fuzzy system is proposed. In the proposed model, a cooperative learning mechanism is constructed to explore the consistent information between views, and Shannon entropy is also introduced to adapt the view weight. On the MVRC dataset, we compared it with several advanced algorithms and DRIMV_TSK obtained the best results.

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arXiv2025

Fuzzy Rule-based Differentiable Representation Learning

Representation learning has emerged as a crucial focus in machine and deep learning, involving the extraction of meaningful and useful features and patterns from the input data, thereby enhancing the performance of various downstream tasks such as classification, clustering, and prediction. Current mainstream representation learning methods primarily rely on non-linear data mining techniques such as kernel methods and deep neural networks to extract abstract knowledge from complex datasets. However, most of these methods are black-box, lacking transparency and interpretability in the learning process, which constrains their practical utility. To this end, this paper introduces a novel representation learning method grounded in an interpretable fuzzy rule-based model. Specifically, it is built upon the Takagi-Sugeno-Kang fuzzy system (TSK-FS) to initially map input data to a high-dimensional fuzzy feature space through the antecedent part of the TSK-FS. Subsequently, a novel differentiable optimization method is proposed for the consequence part learning which can preserve the model's interpretability and transparency while further exploring the nonlinear relationships within the data. This optimization method retains the essence of traditional optimization, with certain parts of the process parameterized corresponding differentiable modules constructed, and a deep optimization process implemented. Consequently, this method not only enhances the model's performance but also ensures its interpretability. Moreover, a second-order geometry preservation method is introduced to further improve the robustness of the proposed method. Extensive experiments conducted on various benchmark datasets validate the superiority of the proposed method, highlighting its potential for advancing representation learning methodologies.

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arXiv2024

Generative Fuzzy System for Sequence Generation

Generative Models (GMs), particularly Large Language Models (LLMs), have garnered significant attention in machine learning and artificial intelligence for their ability to generate new data by learning the statistical properties of training data and creating data that resemble the original. This capability offers a wide range of applications across various domains. However, the complex structures and numerous model parameters of GMs make the input-output processes opaque, complicating the understanding and control of outputs. Moreover, the purely data-driven learning mechanism limits GM's ability to acquire broader knowledge. There remains substantial potential for enhancing the robustness and generalization capabilities of GMs. In this work, we introduce the fuzzy system, a classical modeling method that combines data and knowledge-driven mechanisms, to generative tasks. We propose a novel Generative Fuzzy System framework, named GenFS, which integrates the deep learning capabilities of GM with the interpretability and dual-driven mechanisms of fuzzy systems. Specifically, we propose an end-to-end GenFS-based model for sequence generation, called FuzzyS2S. A series of experimental studies were conducted on 12 datasets, covering three distinct categories of generative tasks: machine translation, code generation, and summary generation. The results demonstrate that FuzzyS2S outperforms the Transformer in terms of accuracy and fluency. Furthermore, it exhibits better performance on some datasets compared to state-of-the-art models T5 and CodeT5.

cs.AI↗

arXiv2024

EMOCPD: Efficient Attention-based Models for Computational Protein Design Using Amino Acid Microenvironment

Computational protein design (CPD) refers to the use of computational methods to design proteins. Traditional methods relying on energy functions and heuristic algorithms for sequence design are inefficient and do not meet the demands of the big data era in biomolecules, with their accuracy limited by the energy functions and search algorithms. Existing deep learning methods are constrained by the learning capabilities of the networks, failing to extract effective information from sparse protein structures, which limits the accuracy of protein design. To address these shortcomings, we developed an Efficient attention-based Models for Computational Protein Design using amino acid microenvironment (EMOCPD). It aims to predict the category of each amino acid in a protein by analyzing the three-dimensional atomic environment surrounding the amino acids, and optimize the protein based on the predicted high-probability potential amino acid categories. EMOCPD employs a multi-head attention mechanism to focus on important features in the sparse protein microenvironment and utilizes an inverse residual structure to optimize the network architecture. The proposed EMOCPD achieves over 80% accuracy on the training set and 68.33% and 62.32% accuracy on two independent test sets, respectively, surpassing the best comparative methods by over 10%. In protein design, the thermal stability and protein expression of the predicted mutants from EMOCPD show significant improvements compared to the wild type, effectively validating EMOCPD's potential in designing superior proteins. Furthermore, the predictions of EMOCPD are influenced positively, negatively, or have minimal impact based on the content of the 20 amino acids, categorizing amino acids as positive, negative, or neutral. Research findings indicate that EMOCPD is more suitable for designing proteins with lower contents of negative amino acids.

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arXiv2023

A Robust Multilabel Method Integrating Rule-based Transparent Model, Soft Label Correlation Learning and Label Noise Resistance

Model transparency, label correlation learning and the robust-ness to label noise are crucial for multilabel learning. However, few existing methods study these three characteristics simultaneously. To address this challenge, we propose the robust multilabel Takagi-Sugeno-Kang fuzzy system (R-MLTSK-FS) with three mechanisms. First, we design a soft label learning mechanism to reduce the effect of label noise by explicitly measuring the interactions between labels, which is also the basis of the other two mechanisms. Second, the rule-based TSK FS is used as the base model to efficiently model the inference relationship be-tween features and soft labels in a more transparent way than many existing multilabel models. Third, to further improve the performance of multilabel learning, we build a correlation enhancement learning mechanism based on the soft label space and the fuzzy feature space. Extensive experiments are conducted to demonstrate the superiority of the proposed method.

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arXiv2023

Graph Fuzzy System: Concepts, Models and Algorithms

Fuzzy systems (FSs) have enjoyed wide applications in various fields, including pattern recognition, intelligent control, data mining and bioinformatics, which is attributed to the strong interpretation and learning ability. In traditional application scenarios, FSs are mainly applied to model Euclidean space data and cannot be used to handle graph data of non-Euclidean structure in nature, such as social networks and traffic route maps. Therefore, development of FS modeling method that is suitable for graph data and can retain the advantages of traditional FSs is an important research. To meet this challenge, a new type of FS for graph data modeling called Graph Fuzzy System (GFS) is proposed in this paper, where the concepts, modeling framework and construction algorithms are systematically developed. First, GFS related concepts, including graph fuzzy rule base, graph fuzzy sets and graph consequent processing unit (GCPU), are defined. A GFS modeling framework is then constructed and the antecedents and consequents of the GFS are presented and analyzed. Finally, a learning framework of GFS is proposed, in which a kernel K-prototype graph clustering (K2PGC) is proposed to develop the construction algorithm for the GFS antecedent generation, and then based on graph neural network (GNNs), consequent parameters learning algorithm is proposed for GFS. Specifically, three different versions of the GFS implementation algorithm are developed for comprehensive evaluations with experiments on various benchmark graph classification datasets. The results demonstrate that the proposed GFS inherits the advantages of both existing mainstream GNNs methods and conventional FSs methods while achieving better performance than the counterparts.

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arXiv2023

Multi-Label Takagi-Sugeno-Kang Fuzzy System

Multi-label classification can effectively identify the relevant labels of an instance from a given set of labels. However,the modeling of the relationship between the features and the labels is critical to the classification performance. To this end, we propose a new multi-label classification method, called Multi-Label Takagi-Sugeno-Kang Fuzzy System (ML-TSK FS), to improve the classification performance. The structure of ML-TSK FS is designed using fuzzy rules to model the relationship between features and labels. The fuzzy system is trained by integrating fuzzy inference based multi-label correlation learning with multi-label regression loss. The proposed ML-TSK FS is evaluated experimentally on 12 benchmark multi-label datasets. 1 The results show that the performance of ML-TSK FS is competitive with existing methods in terms of various evaluation metrics, indicating that it is able to model the feature-label relationship effectively using fuzzy inference rules and enhances the classification performance.

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arXiv2023

Multi-view Fuzzy Representation Learning with Rules based Model

Unsupervised multi-view representation learning has been extensively studied for mining multi-view data. However, some critical challenges remain. On the one hand, the existing methods cannot explore multi-view data comprehensively since they usually learn a common representation between views, given that multi-view data contains both the common information between views and the specific information within each view. On the other hand, to mine the nonlinear relationship between data, kernel or neural network methods are commonly used for multi-view representation learning. However, these methods are lacking in interpretability. To this end, this paper proposes a new multi-view fuzzy representation learning method based on the interpretable Takagi-Sugeno-Kang (TSK) fuzzy system (MVRL_FS). The method realizes multi-view representation learning from two aspects. First, multi-view data are transformed into a high-dimensional fuzzy feature space, while the common information between views and specific information of each view are explored simultaneously. Second, a new regularization method based on L_(2,1)-norm regression is proposed to mine the consistency information between views, while the geometric structure of the data is preserved through the Laplacian graph. Finally, extensive experiments on many benchmark multi-view datasets are conducted to validate the superiority of the proposed method.

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arXiv2023

Deep Image Feature Learning with Fuzzy Rules

The methods of extracting image features are the key to many image processing tasks. At present, the most popular method is the deep neural network which can automatically extract robust features through end-to-end training instead of hand-crafted feature extraction. However, the deep neural network currently faces many challenges: 1) its effectiveness is heavily dependent on large datasets, so the computational complexity is very high; 2) it is usually regarded as a black box model with poor interpretability. To meet the above challenges, a more interpretable and scalable feature learning method, i.e., deep image feature learning with fuzzy rules (DIFL-FR), is proposed in the paper, which combines the rule-based fuzzy modeling technique and the deep stacked learning strategy. The method progressively learns image features through a layer-by-layer manner based on fuzzy rules, so the feature learning process can be better explained by the generated rules. More importantly, the learning process of the method is only based on forward propagation without back propagation and iterative learning, which results in the high learning efficiency. In addition, the method is under the settings of unsupervised learning and can be easily extended to scenes of supervised and semi-supervised learning. Extensive experiments are conducted on image datasets of different scales. The results obviously show the effectiveness of the proposed method.

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arXiv2023

Dual Representation Learning for One-Step Clustering of Multi-View Data

Multi-view data are commonly encountered in data mining applications. Effective extraction of information from multi-view data requires specific design of clustering methods to cater for data with multiple views, which is non-trivial and challenging. In this paper, we propose a novel one-step multi-view clustering method by exploiting the dual representation of both the common and specific information of different views. The motivation originates from the rationale that multi-view data contain not only the consistent knowledge between views but also the unique knowledge of each view. Meanwhile, to make the representation learning more specific to the clustering task, a one-step learning framework is proposed to integrate representation learning and clustering partition as a whole. With this framework, the representation learning and clustering partition mutually benefit each other, which effectively improve the clustering performance. Results from extensive experiments conducted on benchmark multi-view datasets clearly demonstrate the superiority of the proposed method.

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arXiv2023

Cooperation Learning Enhanced Colonic Polyp Segmentation Based on Transformer-CNN Fusion

Traditional segmentation methods for colonic polyps are mainly designed based on low-level features. They could not accurately extract the location of small colonic polyps. Although the existing deep learning methods can improve the segmentation accuracy, their effects are still unsatisfied. To meet the above challenges, we propose a hybrid network called Fusion-Transformer-HardNetMSEG (i.e., Fu-TransHNet) in this study. Fu-TransHNet uses deep learning of different mechanisms to fuse each other and is enhanced with multi-view collaborative learning techniques. Firstly, the Fu-TransHNet utilizes the Transformer branch and the CNN branch to realize the global feature learning and local feature learning, respectively. Secondly, a fusion module is designed to integrate the features from two branches. The fusion module consists of two parts: 1) the Global-Local Feature Fusion (GLFF) part and 2) the Dense Fusion of Multi-scale features (DFM) part. The former is built to compensate the feature information mission from two branches at the same scale; the latter is constructed to enhance the feature representation. Thirdly, the above two branches and fusion modules utilize multi-view cooperative learning techniques to obtain their respective weights that denote their importance and then make a final decision comprehensively. Experimental results showed that the Fu-TransHNet network was superior to the existing methods on five widely used benchmark datasets. In particular, on the ETIS-LaribPolypDB dataset containing many small-target colonic polyps, the mDice obtained by Fu-TransHNet were 12.4% and 6.2% higher than the state-of-the-art methods HardNet-MSEG and TransFuse-s, respectively.

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