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Zhen Jin

Publications and source records attributed to Zhen Jin.

At least 19 recordsLinked to original sources

Time-varying Interaction Graph ODE for Dynamic Graph Representation Learning

Graph neural Ordinary Differential Equations (ODE) combine neural ODE with the message passing mechanism of Graph Neural Networks (GNN), providing a continuous-time modeling method for graph representation learning. However, in dynamic graph scenarios, existing graph neural ODEs typically employ a unified message passing mechanism, assuming that inter-node interactions share the same message passing function at any time, which makes it challenging to capture the diversity and time-varying nature of inter-node interaction patterns. To address this, we propose Time-varying Interaction Graph Ordinary Differential Equations (TI-ODE). The core idea of TI-ODE is to decompose the evolution function of a graph ODE into a set of learnable interaction basis functions, where each basis function corresponds to a distinct type of inter-node interaction. These basis functions are dynamically combined through time-dependent learnable weights, enabling inter-node interaction patterns to adaptively evolve over time. Experimental results on six dynamic graph datasets demonstrate that TI-ODE consistently outperforms existing methods and achieves state-of-the-art performance on attribute prediction tasks, and experiments on the \textit{Covid} dataset further verify the interpretability and generalizability of our TI-ODE. Furthermore, we demonstrate both theoretically and empirically that TI-ODE exhibits superior robustness compared to models utilizing a unified message-passing mechanism.

cs.LG

AugServe: Adaptive Request Scheduling for Augmented Large Language Model Inference Serving

As augmented large language models (LLMs) with external tools become increasingly popular in web applications, improving augmented LLM inference serving efficiency and optimizing service-level objectives (SLOs) are critical for enhancing user experience. To achieve this, inference systems must maximize request handling within latency constraints, referred to as increasing effective throughput. However, existing systems face two major challenges: (i) reliance on first-come-first-served (FCFS) scheduling causes severe head-of-line blocking, leading to queuing delays exceeding the SLOs for many requests; and (ii) static batch token limit, which fails to adapt to fluctuating loads and hardware conditions. Both of these factors degrade effective throughput and service quality. This paper presents AugServe, an efficient inference framework designed to reduce queueing latency and enhance effective throughput for augmented LLM inference services. The core idea of AugServe is a two-stage adaptive request scheduling strategy. Specifically, AugServe combines the inference features of augmented LLM requests to optimize the order of scheduling decisions (stage I). These decisions are continuously refined with runtime information (stage II), adapting to both request characteristics and system capabilities. In addition, AugServe dynamically adjusts the token batching mechanism based on hardware status and real-time load, further enhancing throughput performance. Experimental results show that AugServe achieves 4.7x and 3.3x higher effective throughput than vLLM and InferCept, while reducing time-to-first-token (TTFT) by up to 96.3% and 95.0%, respectively.

cs.CL

Source Detection in Hypergraph Epidemic Dynamics using a Higher-Order Dynamic Message Passing Algorithm

Source detection is crucial for capturing the dynamics of real-world infectious diseases and informing effective containment strategies. Most existing approaches to source detection focus on conventional pairwise networks, whereas recent efforts on both mathematical modeling and analysis of contact data suggest that higher-order (e.g., group) interactions among individuals may both account for a large fraction of infection events and change our understanding of how epidemic spreading proceeds in empirical populations. In the present study, we propose a message-passing algorithm, called the HDMPN, for source detection for a stochastic susceptible-infectious dynamics on hypergraphs. By modulating the likelihood maximization method by the fraction of infectious neighbors, HDMPN aims to capture the influence of higher-order structures and do better than the conventional likelihood maximization. We numerically show that, in most cases, HDMPN outperforms benchmarks including the likelihood maximization method without modification.

physics.soc-ph

First experimental proof of PET imaging based on multi-anode MCP-PMTs with Cherenkov radiator-integrated window

Improving the coincidence time resolution (CTR) of time-of-flight positron emission tomography (TOF-PET) systems to achieve a higher signal-to-noise ratio (SNR) gain or even direct positron emission imaging (dPEI) is of paramount importance for many advanced new clinical applications of PET imaging. This places higher demands on the timing performance of all aspects of PET systems. One effective approach is to use microchannel plate photomultiplier tubes (MCP-PMTs) for prompt Cherenkov photon detection. In this study, we developed a dual-module Cherenkov PET imaging experimental platform, utilising our proprietary 8 * 8-anode Cherenkov radiator-integrated window MCP-PMTs in combination with custom-designed multi-channel electronics, and designed a specific calibration and correction method for the platform. Using this platform, a CTR of 103 ps FWHM was achieved. We overcame the limitations of single-anode detectors in previous experiments, significantly enhanced imaging efficiency and achieved module-level Cherenkov PET imaging for the first time. Imaging experiments involving radioactive sources and phantoms of various shapes and types were conducted, which preliminarily validated the feasibility and advancement of this imaging method. In addition, the effects of normalisation correction and the interaction probability between the gamma rays and the MCP on the images and experimental results were analysed and verified.

physics.ins-det

Design & Optimization of the HV divider for JUNO 20-inch PMT

The Jiangmen Underground Observatory (JUNO) is a 20-kton liquid scintillator detector that employs 20,000 20-inch photomultiplier tubes (PMTs) as photon sensors, with 5,000 dynode-PMTs from HAMAMATSU Photonics K.K. (HPK), and 15,000 MCP-PMTs from North Night Vision Technology (NNVT) installed in pure water. JUNO aims to provide long-lasting and the best performance operation by utilizing a high-transparency liquid scintillator, high detection efficiency PMTs, and specially designed electronics including water-proof potting for the high voltage (HV) dividers of PMTs. In this paper, we present a summary of the design and optimization of HV dividers for both types of 20-inch PMTs, which includes collection efficiency, charge resolution, HV divider current, pulse shape, and maximum amplitude restriction. We have developed and finalized four schemes of the HV divider for different scenarios, including the final version selected by JUNO. All 20,000 20-inch PMTs have successfully undergone production and burning tests.

physics.ins-det

High-performance and Scalable Software-based NVMe Virtualization Mechanism with I/O Queues Passthrough

NVMe(Non-Volatile Memory Express) is an industry standard for solid-state drives (SSDs) that has been widely adopted in data centers. NVMe virtualization is crucial in cloud computing as it allows for virtualized NVMe devices to be used by virtual machines (VMs), thereby improving the utilization of storage resources. However, traditional software-based solutions have flexibility benefits but often come at the cost of performance degradation or high CPU overhead. On the other hand, hardware-assisted solutions offer high performance and low CPU usage, but their adoption is often limited by the need for special hardware support or the requirement for new hardware development. In this paper, we propose LightIOV, a novel software-based NVMe virtualization mechanism that achieves high performance and scalability without consuming valuable CPU resources and without requiring special hardware support. LightIOV can support thousands of VMs on each server. The key idea behind LightIOV is NVMe hardware I/O queues passthrough, which enables VMs to directly access I/O queues of NVMe devices, thus eliminating virtualization overhead and providing near-native performance. Results from our experiments show that LightIOV can provide comparable performance to VFIO, with an IOPS of 97.6%-100.2% of VFIO. Furthermore, in high-density VMs environments, LightIOV achieves 31.4% lower latency than SPDK-Vhost when running 200 VMs, and an improvement of 27.1% in OPS performance in real-world applications.

cs.AR

Optimal control and comprehensive cost-effectiveness analysis for COVID-19

Cost-effectiveness analysis is a mode of determining both the cost and economic health outcomes of one or more control interventions. In this work, we have formulated a non-autonomous nonlinear deterministic model to study the control of COVID-19 to unravel the cost and economic health outcomes for the autonomous nonlinear model proposed for the Kingdom of Saudi Arabia. The optimal control model captures four time-dependent control functions, thus, $u_1$-practising physical or social distancing protocols; $u_2$-practising personal hygiene by cleaning contaminated surfaces with alcohol-based detergents; $u_3$-practising proper and safety measures by exposed, asymptomatic and symptomatic infected individuals; $u_4$-fumigating schools in all levels of education, sports facilities, commercial areas and religious worship centres. We proved the existence of the proposed optimal control model. The optimality system associated with the non-autonomous epidemic model is derived using Pontryagin's maximum principle. We have performed numerical simulations to investigate extensive cost-effectiveness analysis for fourteen optimal control strategies. Comparing the control strategies, we noticed that; Strategy 1 (practising physical or social distancing protocols) is the most cost-saving and most effective control intervention in Saudi Arabia in the absence of vaccination. But, in terms of the infection averted, we saw that strategy 6, strategy 11, strategy 12, and strategy 14 are just as good in controlling COVID-19.

math.OC

Detection of bistable structures via the Conley index and applications to biological systems

Bistability is a ubiquitous phenomenon in life sciences. In this paper, two kinds of bistable structures in dynamical systems are studied: One is two one-point attractors, another is a one-point attractor accompanied by a cycle attractor. By the Conley index theory, we prove that there exist other isolated invariant sets besides the two attractors, and also obtain the possible components and their configuration. Moreover, we find that there is always a separatrix or cycle separatrix, which separates the two attractors. Finally, the biological meanings and implications of these structures are given and discussed.

math.DS

An SIS epidemic model with vaccination in a dynamical contact network of mobile individuals with heterogeneous spatial constraints

Network-based epidemic models have been extensively employed to understand the spread of infectious diseases, but have generally overlooked the fact that most realistic networks are dynamical rather than static. In this paper, we study a susceptible-infected-susceptible epidemic model with vaccination in a dynamical contact network of moving individuals, where we regard mobile individuals as random walkers that are allowed to perform long-range jumps. Different from previous studies of epidemics in a random walk network with a constant interaction radius, we consider the scenario where the individuals have a heterogeneous distribution of interaction radius $r$ and infected individuals are vaccinated with a probability depending on the interaction radius distribution. We derive the basic reproduction number $\mathcal{R}_0$ and explore the stability of disease-free and endemic equilibria of the model. Both theoretical and simulation results reveal that the distribution of individual interaction radius has significant effects on the basic reproduction number and the epidemic prevalence. In general, the disease will break out more readily in the population with a more heterogeneous radius distribution; however resulting in a lower epidemic prevalence. Interestingly, the results suggest that an optimal vaccination intervention for disease prevention and control is achievable regardless of the radius distribution. Furthermore, some interesting results on the structure of the underlying contact network are shown to have strong correlation with the epidemic dynamics. This study provides potential implications for developing efficient containment measures against infectious disease while considering the spatial constraints of moving individuals.

physics.soc-ph

Epidemic spread in interconnected directed networks

In the real world, many complex systems interact with other systems. In addition, the intra- or inter-systems for the spread of information about infectious diseases and the transmission of infectious diseases are often not random, but with direction. Hence, in this paper, we build epidemic model based on an interconnected directed network, which can be considered as the generalization of undirected networks and bipartite networks. By using the mean-field approach, we establish the Susceptible-Infectious-Susceptible model on this network. We theoretically analyze the model, and obtain the basic reproduction number, which is also the generalization of the critical number corresponding to undirected or bipartite networks. And we prove the global stability of disease-free and endemic equilibria via the basic reproduction number as a forward bifurcation parameter. We also give a condition for epidemic prevalence only on a single subnetwork. Furthermore, we carry out numerical simulations, and find that the independence between each node's in- and out-degrees greatly reduce the impact of the network's topological structure on disease spread.

physics.soc-ph

Prevention of infectious diseases by public vaccination and individual protection

In the face of serious infectious diseases, governments endeavour to implement containment measures such as public vaccination at a macroscopic level. Meanwhile, individuals tend to protect themselves by avoiding contacts with infections at a microscopic level. However, a comprehensive understanding of how such combined strategy influences epidemic dynamics is still lacking. We study a susceptible-infected-susceptible epidemic model with imperfect vaccination on dynamic contact networks, where the macroscopic intervention is represented by random vaccination of the population and the microscopic protection is characterised by susceptible individuals rewiring contacts from infective neighbours. In particular, the model is formulated both in populations without and then with demographic effects. Using the pairwise approximation and the probability generating function approach, we investigate both dynamics of the epidemic and the underlying network. For populations without demography, the emerging degree correlations, bistable states, and oscillations demonstrate the combined effects of the public vaccination program and individual protective behavior. Compared to either strategy in isolation, the combination of public vaccination and individual protection is more effective in preventing and controlling the spread of infectious diseases by increasing both the invasion threshold and the persistence threshold. For populations with additional demographic factors, the integration between vaccination intervention and individual rewiring may promote epidemic spreading due to the birth effect. Moreover, the degree distributions of both networks in the steady state is closely related to the degree distribution of newborns, which leads to uncorrelated connectivity. All the results demonstrate the importance of both local protection and global intervention, as well as the demographic effects.

physics.soc-ph

Persistence, extinction and spatio-temporal synchronization of SIRS cellular automata models

Spatially explicit models have been widely used in today's mathematical ecology and epidemiology to study persistence and extinction of populations as well as their spatial patterns. Here we extend the earlier work--static dispersal between neighbouring individuals to mobility of individuals as well as multi-patches environment. As is commonly found, the basic reproductive ratio is maximized for the evolutionary stable strategy (ESS) on diseases' persistence in mean-field theory. This has important implications, as it implies that for a wide range of parameters that infection rate will tend maximum. This is opposite with present results obtained in spatial explicit models that infection rate is limited by upper bound. We observe the emergence of trade-offs of extinction and persistence on the parameters of the infection period and infection rate and show the extinction time having a linear relationship with respect to system size. We further find that the higher mobility can pronouncedly promote the persistence of spread of epidemics, i.e., the phase transition occurs from extinction domain to persistence domain, and the spirals' wavelength increases as the mobility increasing and ultimately, it will saturate at a certain value. Furthermore, for multi-patches case, we find that the lower coupling strength leads to anti-phase oscillation of infected fraction, while higher coupling strength corresponds to in-phase oscillation.

q-bio.PE

Complex dynamics of a Holling-type IV predator-prey model

In this paper, we focus on a spatial Holling-type IV predator-prey model which contains some important factors, such as diffusion, noise (random fluctuations) and external periodic forcing. By a brief stability and bifurcation analysis, we arrive at the Hopf and Turing bifurcation surface and derive the symbolic conditions for Hopf and Turing bifurcation in the spatial domain. Based on the stability and bifurcation analysis, we obtain spiral pattern formation via numerical simulation. Additionally, we study the model with colored noise and external periodic forcing. From the numerical results, we know that noise or external periodic forcing can induce instability and enhance the oscillation of the species, and resonant response. Our results show that modeling by reaction-diffusion equations is an appropriate tool for investigating fundamental mechanisms of complex spatiotemporal dynamics.

q-bio.PE

Spatiotemporal pattern formation of Beddington-DeAngelis-type predator-prey model

In this paper, we investigate the emergence of a predator-prey model with Beddington-DeAngelis-type functional response and reaction-diffusion. We derive the conditions for Hopf and Turing bifurcation on the spatial domain. Based on the stability and bifurcation analysis, we give the spatial pattern formation via numerical simulation, i.e., the evolution process of the model near the coexistence equilibrium point. We find that for the model we consider, pure Turing instability gives birth to the spotted pattern, pure Hopf instability gives birth to the spiral wave pattern, and both Hopf and Turing instability give birth to stripe-like pattern. Our results show that reaction-diffusion model is an appropriate tool for investigating fundamental mechanism of complex spatiotemporal dynamics. It will be useful for studying the dynamic complexity of ecosystems.

q-bio.PE

Resonance and frequency-locking phenomena in spatially extended phytoplankton-zooplankton system with additive noise and periodic forces

In this paper, we present a spatial version of phytoplankton-zooplankton model that includes some important factors such as external periodic forces, noise, and diffusion processes. The spatially extended phytoplankton-zooplankton system is from the original study by Scheffer [M Scheffer, Fish and nutrients interplay determines algal biomass: a minimal model, Oikos \textbf{62} (1991) 271-282]. Our results show that the spatially extended system exhibit a resonant patterns and frequency-locking phenomena. The system also shows that the noise and the external periodic forces play a constructive role in the Scheffer's model: first, the noise can enhance the oscillation of phytoplankton species' density and format a large clusters in the space when the noise intensity is within certain interval. Second, the external periodic forces can induce 4:1 and 1:1 frequency-locking and spatially homogeneous oscillation phenomena to appear. Finally, the resonant patterns are observed in the system when the spatial noises and external periodic forces are both turned on. Moreover, we found that the 4:1 frequency-locking transform into 1:1 frequency-locking when the noise intensity increased. In addition to elucidating our results outside the domain of Turing instability, we provide further analysis of Turing linear stability with the help of the numerical calculation by using the Maple software. Significantly, oscillations are enhanced in the system when the noise term presents. These results indicate that the oceanic plankton bloom may partly due to interplay between the stochastic factors and external forces instead of deterministic factors. These results also may help us to understand the effects arising from undeniable subject to random fluctuations in oceanic plankton bloom.

q-bio.PE

Emergence of spatiotemporal chaos driven by far-field breakup of spiral waves in the plankton ecological systems

Alexander B. Medvinsky \emph{et al} [A. B. Medvinsky, I. A. Tikhonova, R. R. Aliev, B.-L. Li, Z.-S. Lin, and H. Malchow, Phys. Rev. E \textbf{64}, 021915 (2001)] and Marcus R. Garvie \emph{et al} [M. R. Garvie and C. Trenchea, SIAM J. Control. Optim. \textbf{46}, 775-791 (2007)] shown that the minimal spatially extended reaction-diffusion model of phytoplankton-zooplankton can exhibit both regular, chaotic behavior, and spatiotemporal patterns in a patchy environment. Based on that, the spatial plankton model is furtherly investigated by means of computer simulations and theoretical analysis in the present paper when its parameters would be expected in the case of mixed Turing-Hopf bifurcation region. Our results show that the spiral waves exist in that region and the spatiotemporal chaos emerge, which arise from the far-field breakup of the spiral waves over large ranges of diffusion coefficients of phytoplankton and zooplankton. Moreover, the spatiotemporal chaos arising from the far-field breakup of spiral waves does not gradually involve the whole space within that region. Our results are confirmed by means of computation spectra and nonlinear bifurcation of wave trains. Finally, we give some explanations about the spatially structured patterns from the community level.

nlin.PS

Spatiotemporal complexity of a ratio-dependent predator-prey system

In this paper, we investigate the emergence of a ratio-dependent predator-prey system with Michaelis-Menten-type functional response and reaction-diffusion. We derive the conditions for Hopf, Turing and Wave bifurcation on a spatial domain. Furthermore, we present a theoretical analysis of evolutionary processes that involves organisms distribution and their interaction of spatially distributed population with local diffusion. The results of numerical simulations reveal that the typical dynamics of population density variation is the formation of isolated groups, i.e., stripelike or spotted or coexistence of both. Our study shows that the spatially extended model has not only more complex dynamic patterns in the space, but also chaos and spiral waves. It may help us better understand the dynamics of an aquatic community in a real marine environment.

q-bio.PE

Spatial organization and evolutional period of the epidemic model using cellular automata

We investigate epidemic models with spatial structure based on the cellular automata method. The construction of the cellular automata is from the study by Weimar and Boon about the reaction-diffusion equations [Phys. Rev. E 49, 1749 (1994)]. Our results show that the spatial epidemic models exhibit the spontaneous formation of irregular spiral waves at large scales within the domain of chaos. Moreover, the irregular spiral waves grow stably. The system also shows a spatial period-2 structure at one dimension outside the domain of chaos. It is interesting that the spatial period-2 structure will break and transform into a spatial synchronous configuration in the domain of chaos. Our results confirm that populations embed and disperse more stably in space than they do in nonspatial counterparts.

nlin.CG