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Zhen Lei

Publications and source records attributed to Zhen Lei.

At least 19 recordsLinked to original sources

Graph-structured joint-embedding prediction for single-cell transcriptomics

Single-cell transcriptomes are sparse, unordered measurements of coordinated biological activity, yet many self-supervised models define their learning target at the level of individual genes or reconstructed expression values. Here we introduce GB-JEPA, a joint-embedding predictive architecture in which graph-connected gene blocks form the latent prediction units. A student encoder observes the genes outside each target block, whereas an exponential-moving-average teacher represents the full observed gene set. Teacher states are aggregated within a block before the prediction error is evaluated, converting thousands of sparse gene-level targets into a small collection of intermediate-scale latent targets. The graph therefore serves not only as prior information, but also as a mechanism for controlling the structure, scale and predictability of self-supervision. We evaluate the resulting frozen cell representations through objective diagnostics, cell-state annotation, continuous-expression and pathway probes, perturbation-response prediction, computational measurements and direct biological interrogation. This study presents a graph-structured route for adapting JEPA learning to molecular observations and a general framework for designing prediction units from relationships native to a biological modality.

cs.LG↗

Vision Tomography: Towards Portable 3D Bidirectional Face-Skull Inference from Visual Data

Traditional computed tomography (CT) can capture paired 3D face and skull geometry, but it remains costly, fixed in location, and exposes patients to radiation. For applications such as remote diagnostics, digital healthcare, forensic identification, missing-person investigation, and archaeological analysis, there is an urgent need for a portable, safe, and accessible solution to capture 3D skull geometry. In this work, we introduce Vision Tomography (VT), a concept and framework capable of reconstructing paired 3D face-skull geometry from various visual modalities, and also enabling joint manipulation of 3D facial and skull geometry. To achieve this, we first construct a dataset of over 200 samples, where each case includes a CT-based skull, a CT-based face, and a high-fidelity textured face scan. Secondly, we propose a novel dense ray matching registration method that ensures topological consistency across face, skull, and their tissue correspondences. Building on this registration, we introduce the 3D Bidirectional Face-Skull Morphable Model (BFSM) as the foundation of Vision Tomography, which enables shape inference between the face and skull through a shared coefficient space, while also modeling tissue thickness variation to support one-to-many facial reconstructions from the same skull, reflecting individual facial changes such as age or body fat. Finally, we demonstrate the effectiveness of Vision Tomography across various forensic and medical applications, including paired 3D face-skull reconstruction from images or sketches and predicting surgical outcomes with joint face-skull editing. Extensive experiments confirm the robustness and accuracy of our method. Vision Tomography is available at https://github.com/wang-zidu/BFSM

cs.CV↗

From Suppression to Repair: Mitigating Object Hallucination in Large Vision-Language Models via Localized Distribution Alignment

Object hallucination remains a major obstacle for large vision-language models (LVLMs) to generate reliable content. An intuitive mitigation strategy is to suppress hallucination-related components in hidden representations. However, these components may also contain useful information, and suppressing them can weaken the model's multimodal capabilities. In this paper, we propose ResOT, a training-free method that repairs representations at inference time through localized distribution alignment. Specifically, ResOT projects dominant hallucinated directions away from the faithful subspace, forming a low-dimensional residual subspace for intervention. Within this subspace, ResOT uses Gaussian optimal transport (OT) to align the hallucinated distribution with the faithful one. The resulting map defines repair targets with minimal changes to the original representations. At inference, ResOT adaptively controls how far each token state moves toward its OT target. Experiments on three representative LVLMs show that ResOT substantially reduces object hallucination while improving image caption quality and multimodal performance across multiple benchmarks. Code will be released.

cs.CV↗

Talk Like You: Imitating How You Speak in Real-Time Talking Head Generation

In daily life, each person exhibits unique speaking habits, leading to subtle yet consistent lip-shape variations even when pronouncing the same word. Although recent talking head generation methods have achieved impressive visual fidelity and lip synchronization, they largely overlook user-specific customization, especially the motion patterns that characterize individual speaking habits. These habits are difficult to model and capture, as their motion patterns are highly fine-grained and often similar across individuals. As a result, many approaches produce overly uniform facial motions and fail to capture diverse, person-specific articulation patterns. To address this, we propose TalkLikeYou, an efficient framework that imitates how a target person speaks in talking head generation. Our method models habit in motion-space and achieves real-time performance through Flow Matching with only one sampling step during inference. We further adopt a two-stage imitation learning strategy to capture subtle distinctions between habits, allowing users to specify a target habit through either a preset style from the dataset or a reference video. In addition, we introduce a new metric PLAD that projects mouth motions onto representative articulation axes to evaluate imitation accuracy and generation diversity. Extensive experiments demonstrate that TalkLikeYou generates high-quality talking heads in real-time and significantly improves speaking habit imitation compared with prior methods. The code is available at: https://github.com/BQ-Wang0511/TalkLikeYou

cs.CV↗

Geometric Similarity in VLM Low-Level Vision Representations

Vision-language models (VLMs) have emerged as powerful candidates for universal vision backbones, with representative architectures including autoregressive (AR) models and diffusion transformers (DiTs). Yet, adapting them efficiently for all-in-one low-level image restoration remains a challenge. Crucially, the field lacks an understanding of how VLMs organize hidden-layer representations and whether these structurally distinct paradigms share a common geometric organization for pixel-level perception. Such shared organization is a prerequisite for building highly transferable, unified restoration VLMs and adapters. In this paper, we systematically investigate representational similarity across 24 low-level tasks spanning 5 categories. We propose GeoSim, a unified four-level framework that analyzes task-conditioned representations from global similarity, local geometry, sparse feature decomposition, and topological verification perspectives. Our formulation applies to the analysis of hidden states in AR models and feature maps in DiTs across same- and cross-task/model settings. Our results reveal the organizing principles of low-level visual representations while exposing their limits in cross-task and cross-model agreement. Ultimately, GeoSim provides an interpretability lens for probing latent transferability in low-level vision and diagnosing model limitations in task- or model-specific scenarios.

cs.CV↗

Object-Centric Conditioning for Visuomotor Flow Matching

Robot visuomotor policies are commonly formulated as autoregressive, diffusion-based, or more recently, flow matching models. Among them, Action-to-Action (A2A) flow matching improves inference efficiency by initializing generation from historical action priors rather than stochastic noise. However, stale historical motion patterns and entangled global visual representations can jointly reduce robustness under spatial out-of-distribution (OOD) shifts and visual distractors. In this work, we propose SlotFlow, an object-centric flow matching policy for robust visuomotor manipulation. SlotFlow decouples scene observations into semantic ("what") features and lightweight image-plane spatial ("where") cues to provide object-aware policy conditioning and current-state grounding. The semantic representation suppresses irrelevant background correlations, while the spatial cue improves adaptation to shifted object configurations. Extensive simulation and real-world experiments demonstrate improved robustness under visual distractors and severe spatial perturbations while preserving the low-step inference efficiency of A2A. Controlled initialization and perception ablations further identify object-centric grounding as a major source of the gains and show that it complements, rather than replaces, useful historical motion priors.

cs.RO↗

Finite-Time Blowup for Navier-Stokes with Smooth Forcing, Part I: Construction of Self-Similar Solutions with Admissible Stress and Flat Remainder

This paper gives a readable and accessible version of the profile-construction part of OpenAI's manuscript "Finite Time Blowup for Navier-Stokes". We regard OpenAI's work as a major advance on the Navier-Stokes Millennium Prize Problem. The profiles are smooth and axi-symmetric. Inserting them into the Navier-Stokes equations gives a residual consisting of a divergence-form term and a remainder vanishing to infinite order in $1-t$ on fixed similarity sectors. The associated stress and radial shear satisfy the admissible cone condition. The stress need not be small. We introduce a new linear model that provides a clearer explanation of the inner core construction. The cancellation by oscillatory pulses will be treated in the companion paper "Finite-Time Blowup for Navier-Stokes with Smooth Forcing, Part II: Residual Correction via Oscillatory Pulses".

math.AP↗

CellScientist: From Execution Feedback to Auditable Model-Revision Trajectories for Cellular Perturbation Prediction

Cellular perturbation-response modeling requires coordinated choices of representations, fusion mechanisms, objectives, and training procedures. Large language models (LLMs) can propose executable candidates, but unconstrained revision can produce invalid implementations, change task semantics, or discard useful components. We present CellScientist, a protocol-constrained workflow that converts execution and validation feedback into auditable model-revision trajectories. It records design states and outcomes, routes discrepancies to specific components, and applies local revisions under a fixed task contract. A matched-budget study fixes the candidate language, predictor, fitting, and evaluator: structured revision finds better held-out predictors at small budgets under two LLM backbones. Operational audits link history to fewer repeated proposals, contract checks to contained violations, and discrepancy routing to targeted repairs. Refits of two frozen designs on an independently acquired cohort evaluate external predictive utility. Open-workflow trajectories retain improvements, regressions, and failures, while transcriptomic and single-cell searches extend application to additional response spaces. CellScientist produces both a selected predictor and an inspectable record of its development. Project page: https://limengran98.github.io/CellScientist/.

cs.LG↗

VisionHOPE: Visual Backbones as Self-Modifying Learning Systems

Visual backbones have evolved from Convolutional Neural Networks (CNNs) with local aggregation to Vision Transformers (ViTs) with global interactions, State-Space Models (SSMs) with input-dependent state transitions, and Test-Time Training (TTT) layers that adapt an inner learner while processing an image. Across this progression, visual computation has become increasingly adaptive to each input, yet the rules governing that adaptation remain largely prescribed by the trained backbone. We introduce VisionHOPE, the first generic visual backbone formulated as a self-modifying learning system, in which what the model remembers and how it learns co-evolve within an image. Building on the self-referential construction of Nested Learning (NL), VisionHOPE realizes this co-evolution through five coupled memories that store content, generate key and value representations, and govern learning rate and retention. These memories evolve jointly as visual context accumulates along each scan. However, directly applying the unconstrained self-referential update to a visual backbone leads to instability. We therefore derive a stability-matched step-size control scheme that combines a soft cap on self-referential injection with a spectral clamp on the retained memory transition, and prove that the resulting memory dynamics are non-expansive along each scan. For two-dimensional feature maps, we adapt NL's chunk formulation by aligning chunks with image rows and columns across four directional scans. The proposed VisionHOPE achieves competitive results on ImageNet-1K, COCO, and ADE20K, establishing self-modifying learning systems as a practical foundation for general-purpose visual backbones. The code is available at https://github.com/PSRben/VisionHOPE.

cs.CV↗

SurgMotion: A Video-Native Foundation Model for Universal Understanding of Surgical Videos

While foundation models have advanced surgical video analysis, current approaches rely predominantly on pixel-level reconstruction objectives that waste model capacity on low-level visual details, such as smoke, specular reflections, and fluid motion, rather than semantic structures essential for surgical understanding. We present SurgMotion, a video-native foundation model that shifts the learning paradigm from pixel-level reconstruction to latent motion prediction. Built on the Video Joint Embedding Predictive Architecture (V-JEPA), SurgMotion introduces three key technical innovations tailored to surgical videos: (1) motion-guided latent masked prediction to prioritize semantically meaningful regions, (2) spatiotemporal affinity self-distillation to enforce relational consistency, and (3) spatiotemporal feature diversity regularization (SFDR) to prevent representation collapse in texture-sparse surgical scenes. To enable large-scale pretraining, we curate SurgMotion-15M, the largest surgical video dataset to date, comprising 3,658 hours of video from 50 sources across 13 anatomical regions. Extensive experiments across 17 benchmarks demonstrate that SurgMotion significantly outperforms state-of-the-art methods on surgical workflow recognition, achieving 14.6 percent improvement in F1 score on EgoSurgery and 10.3 percent on PitVis; on action triplet recognition with 39.54 percent mAP-IVT on CholecT50; as well as on skill assessment, polyp segmentation, and depth estimation. These results establish SurgMotion as a new standard for universal, motion-oriented surgical video understanding.

cs.CV↗

Relightable 3D Avatar Reconstruction with Semantic-Adaptive Motion-Illumination Responses

Reconstructing expressive and relightable 3D head avatars from monocular videos remains challenging in computer vision, as it requires accurate modeling of both non-rigid facial motion and illumination-dependent appearance. Existing Gaussian avatar methods commonly rely on globally coupled representations, in which Gaussian primitives share a unified motion or illumination response model. Such uniform modeling neglects the distinct motion patterns and material/reflectance properties of different facial semantic regions, thereby limiting fine-grained animation accuracy and reducing relighting plausibility. To address this limitation, we propose SAMIRA, a 3D Gaussian avatar framework for semantic-adaptive motion-illumination response modeling. For motion response modeling, the Semantic-Adaptive Motion Response module rasterizes current-to-reference mesh displacements into a topology-consistent UV space and leverages facial semantics to route displacement features through semantic-specific modulators, predicting localized Gaussian geometric residuals beyond coarse mesh binding. For illumination response modeling, the Semantic-Adaptive Illumination Response module learns compact diffuse and specular response factors for each facial region, allowing Gaussians in different regions to adapt their illumination responses to novel environment lighting. These response factors are incorporated into deferred physically based shading, providing a lightweight approximation of semantic-dependent illumination effects. Extensive experiments on self-reenactment, cross-reenactment, and relighting demonstrate that SAMIRA improves both fine-grained expression reconstruction and relighting realism over existing methods.

cs.CV↗

Global Well-posedness and Regularity of the Dynamical Prandtl Equation

In this paper, we study the dynamical Prandtl equation, which plays an important role in the study of the vanishing viscosity limit of the Navier--Stokes equations. Our focus is on the (Sobolev) well-posedness regime, where the given data satisfy a crucial monotonicity condition. In this case, local classical solutions have been constructed in the pioneering works of Oleinik \cite{O68,OS99}. More recently, global weak solutions were obtained in \cite{XZ04} by Xin and Zhang, and in \cite{XZZ24} by Xin, Zhang, and Zhao, where the uniqueness and interior H"older estimates of the solutions were established (in Crocco coordinates). Using a precise description of the fundamental solution to the Kolmogorov equation in the half-space, we first obtain the H"older regularity of local weak solutions up-to-boundary. We also provide a detailed proof of higher-order regularity estimates together with $W^{2,p}$ Sobolev estimates and $H^{s}$ hypoelliptic estimates, which are nontrivial. Up-to-boundary smoothness of solutions (in Crocco coordinates) is important in order to conclude the smoothness of the Prandtl solutions in the physical variables, even in the interior. It is also physically significant for applications to the Boundary Layer Theory where the dynamical Prandtl equation is essential. Using these smoothing estimates, we then prove the global existence and regularity of classical solutions to the dynamical Prandtl equation under monotonicity assumptions, which was listed by Oleinik and Samokhin in \cite{OS99} as one of the open problems. We also develop a self-contained local existence theory using weighted energy estimates and further expand the theory of global weak solutions. The main point is to incorporate all physical types of asymptotic matching of the boundary layer with the outer flow, which is expected to be useful for applications to the Navier--Stokes equations.

math.AP↗

Reduce the Artifacts Bias for More Generalizable AI-Generated Image Detection

As the misuse of AI-generated images grows, generalizable image detection techniques are urgently needed. Recent state-of-the-art (SOTA) methods adopt aligned training datasets to reduce content, size, and format biases, empowering models to capture robust forgery cues. A common strategy employs reconstruction techniques, e.g., VAE and DDIM, to construct aligned synthetic negatives. However, relying on a single reconstruction process yields a narrow and homogeneous artifact distribution, leaving forensic traces from other artifact-forming mechanisms underrepresented. To broaden artifact coverage without sacrificing alignment, we construct adversarial restoration-based negatives with SRGAN, whose learned upsampling and texture restoration yield traces complementary to VAE reconstruction while preserving content, size, and format. Directly mixing the two aligned fake domains is nontrivial because their artifact manifolds and optimization directions can conflict. We therefore propose Artifact-Complementary Expert Fusion (ACEF), a two-stage framework for robust AIGC detection. ACEF first constructs two artifact-specific experts via LoRA adaptation on a frozen foundation backbone. It then freezes them and introduces Layer-wise Artifact-Complementary Fusion (LACF) to integrate multi-layer source-specific and cross-artifact evidence through an adaptive gate. Extensive experiments on 13 diverse benchmarks demonstrate the effectiveness of our method.

cs.CV↗

MoE-Enhanced Explainable Deep Manifold Transformation for Complex Data Embedding and Visualization

Dimensionality reduction (DR) plays a crucial role in various fields, including data engineering and visualization, by simplifying complex datasets while retaining essential information. However, achieving both high DR accuracy and strong explainability remains a fundamental challenge, especially for users dealing with high-dimensional data. Traditional DR methods often face a trade-off between precision and transparency, where optimizing for performance can lead to reduced explainability, and vice versa. This limitation is especially prominent in real-world applications such as image, tabular, and text data analysis, where both accuracy and explainability are critical. To address these challenges, this work introduces the MoE-based Explainable Deep Manifold Transformation (DMT-ME). The proposed approach combines a geometry-aware hyperbolic mapper with Mixture of Experts (MoE) models, where sparse expert specialization provides the main representational gain and the hyperbolic component offers an additional refinement for structurally complex data. DMT-ME enhances DR accuracy primarily through MoE-based sparse routing and structure-aware matching, while also improving explainability by explicitly linking input data, embedding outcomes, and key features through the MoE structure. Extensive experiments demonstrate that DMT-ME consistently achieves superior performance in both DR accuracy and model explainability, making it a robust solution for complex data analysis. The code is available at https://github.com/zangzelin/code_dmtme.

cs.LG↗

General Probabilities of Causation with Causal Knowledge

Probabilities of causation (PoCs) characterize individual causal responses that cannot be directly observed and therefore generally require partial identification. Tian and Pearl first derived theoretically sharp bounds for binary PoCs, including the probability of necessity (PN), the probability of sufficiency (PS), and the probability of necessity and sufficiency (PNS). Mueller et al. subsequently tightened the bounds for binary PNS by incorporating causal information encoded in covariates and mediators. More recently, Li and Pearl, as well as Shu et al., extended PoCs to multivalued settings and derived corresponding theoretical bounds. These developments naturally raise the question of whether additional causal knowledge can further tighten the bounds in multivalued settings. This paper addresses this question by deriving tighter bounds for multivalued PoCs through the incorporation of causal information encoded in covariates and mediators. We illustrate the theoretical results with toy examples, while simulation studies further demonstrate that the proposed bounds are tighter than existing nonbinary bounds.

cs.AI↗

Evidence-Grounded Forensic Reasoning for Detecting and Grounding Multi-Modal Media Manipulation

Fake news increasingly relies on cross-modal image-text forgeries, making transparent and verifiable reasoning chains an urgent need for Detecting and Grounding Multi-Modal Media Manipulation (DGM4). Existing methods produce black-box detection results without any decision rationale, limiting their reliability in forensic practice. Multi-modal Large Language Models (MLLMs) offer a natural path toward explainability, but applying them to DGM4 raises two difficulties. First, models tend to generate explanations disconnected from predicted evidence locations, producing unverified attribution. Second, enforcing evidence-conclusion consistency requires active optimization, yet uniform training signals fail to distinguish localization tokens from classification tokens, making multi-head joint training unreliable. We propose a multi-modal manipulation detector based on an Evidence-Grounded Forensic Reasoning (EFR) framework. EFR introduces an Anchor-and-Verify reasoning chain that enforces modality-isolated perception before cross-modal comparison, with conclusion coordinates as explicit anchors to which downstream evidence must spatially correspond. A verifiable reward system then enforces evidence-conclusion consistency during training, while a Modality-Decoupled Advantage (MDA) routing mechanism mitigats credit misassignment across prediction tasks. Experiments show that EFR achieves state-of-the-art performance while producing structured forensic reasoning records that explicitly bind explanations to evidence.

cs.CV↗

Private Face Recognition Training Dataset Publication via Identity-Decoupled and Geometry-Preserving Face Distillation

Publishing private face recognition~(FR) training datasets is privacy-sensitive because faces expose identity information. Private FR training dataset publication mitigates this risk by releasing protected proxies as substitutes for private training faces. However, training FR models with such data introduces an identity paradox: \emph{the identity cues that make released faces useful for recognition supervision are also the cues that make them linkable to real individuals.} A protected face should be decoupled from the original identity, yet still behave as a reliable identity sample for training. Removing these cues too aggressively may destroy the class structure needed for recognition learning, whereas preserving them too faithfully may increase source-identity linkability. We argue that this paradox stems from conflating source-aligned identity semantics with recognition-useful proxy identity geometry. The former should be suppressed to reduce linkage to private individuals, while the latter should be preserved for FR learning. Based on this insight, we propose \textbf{Private Face Distillation}, an identity-decoupling and geometry-preserving framework. It uses Orthogonal Geometry Preservation to construct decoupled proxy identities from private identity representations while maintaining hyperspherical geometry, and Relational Topology Alignment to preserve identity relations for recognition learning. Experiments across multiple domain-shifted FR scenarios show that Private Face Distillation achieves stronger utility than the evaluated publication baselines. On IJB-C surveillance, it improves $\mathrm{TAR}@\mathrm{FAR}{=}1\text{e-}{3}$ by 3.94\% over the baseline while reducing source-identity linkability. These results suggest that private FR training dataset publication should decouple source-identity correspondence while preserving proxy identity geometry.

cs.CV↗

Self-Supervised Skill Optimization

Agent skills provide frozen large language model (LLM) agents with reusable procedural guidance, and recent work shows that such skills can be optimized with ground-truth (GT) feedback. Many applications, however, lack GT labels, task scores, rewards, or reliable task-specific evaluators. We therefore introduce Self-Supervised Skill Optimization (SSO), a comparative framework that learns a reusable skill from unlabeled task instances alone. At each step, SSO runs the current skill on an unlabeled batch, uses a subset of the resulting executions to generate complete skill probes, and runs the probes on the same batch. An LLM judge compares the resulting answers, trajectories, artifacts, or terminal states. A separate behavior extractor identifies behavioral differences without seeing the judge's decisions. SSO uses these decisions to aggregate evidence for and against the observed behaviors across instances. It then ranks the behaviors by the resulting evidence and renders a new complete skill from the highest-ranked behaviors. The update is accepted only if the new skill outperforms the current one on an unlabeled validation set. SSO outperforms existing GT-free prompt optimizers on both closed-ended and open-ended tasks. On closed-ended benchmarks, it approaches and sometimes exceeds the strongest GT-based skill optimizer without using any GT feedback.

cs.CL↗