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Zhenchao Tang

Publications and source records attributed to Zhenchao Tang.

8 recordsLinked to original sources

LLM-based Agents for Forecasting and Prediction: Methods, Training, Evaluation, and Applications

Large language models (LLMs) now support forecasting systems that combine language-based reasoning with temporal data, evidence retrieval, external tools, and iterative prediction. We investigate LLM-based forecasting agents, meaning systems in which a language model contributes to a scored prediction about a future or currently unobserved target. We organize architectures into three groups. Standalone LLM workflows operate on encoded time series or event context. Tool- and retrieval-augmented agents incorporate external evidence. Hybrid systems pair LLMs with statistical or foundation models. We then review training methods and evaluation protocols. We examine negative as well as positive evidence, including sensitivity to small input perturbations, ablations in which the LLM component does not improve accuracy, and benchmark gains that may reflect contamination instead of temporal reasoning. We cover applications in finance, weather, health, energy, and operations, and we summarize the benchmarks and datasets used for evaluation. The evidence indicates that measurement is a central limitation. Future work requires calibration under distribution shift, contamination-resistant live evaluation, explicit reporting of cost and accuracy together, and methods for handling feedback between deployed forecasts and the outcomes being forecast.

cs.AI

PertMind: Eliciting Emergent Biological Reasoning in LLM via Reinforcement Learning on Cellular Perturbation Data

Large language models can describe mechanisms, yet scalable post-training still depends on costly, manually curated biological reasoning traces. Here we show that cellular perturbation atlases can instead become reinforcement-learning environments, where measured gene responses provide computable rewards for biological reasoning. We introduce PertMind, which combines trusted-trajectory supervised initialization with gene-, pathway-, and format-level reinforcement signals. Trained only on forward perturbation-response prediction, PertMind improved response inference in unseen cellular contexts while retaining general language capabilities. It also transferred without task-specific post-training to reverse perturbation identification, double-perturbation reasoning, phenotypic-screen prioritization, and biological-process interpretation. PertMind further generated biological profiles that supported competitive gene, cell, and donor representations across multiscale downstream tasks. These results support the hypothesis that reinforcement on experimental endpoints can concentrate reusable biological strategies already accessible to pretrained models. More broadly, perturbation-derived reinforcement learning offers a scalable route for transforming expanding experimental atlases into training environments for general-purpose biological reasoning.

cs.LG

Branch-JEPA: Finite-Support Predictive Distributions for JEPA World Models

Joint-embedding predictive architectures (JEPAs) learn dynamics by predicting future observations in representation space. Yet most JEPA world models return one latent successor, even when hidden intent, partial observation, or stochastic dynamics make several futures plausible. We introduce Branch-JEPA, which replaces this point-valued transition with a context-weighted finite set of latent successors. Every branch is decoded independently, and the complete set is retained at inference. The architecture supports two complementary training regimes: specialization for recovering separated successors and full-set Energy-Score training for distributional fidelity. In a locked five-seed evaluation on the Argoverse~2 official validation split, full-set training improves trajectory Energy Score by $5.8$--$6.5\%$ and probability-weighted trajectory distance by $9.3$--$10.4\%$ over matched-$K{=}6$ assignment and transport objectives, while retaining $5.36$ endpoint-deduplicated effective branches. In a parameter-exact official-validation comparison, latent branching retains $10.3\%$ more effective modes and improves Energy Score, expected ADE, and Brier in all five paired seeds over branching only at the output decoder; every paired 95\% interval excludes zero. In an OGBench graph audit, Branch-JEPA increases teleport verified-route existence to $19.2\%$ versus $3.9\%$ for the MDN. Its raw-support advantage also persists with 29-D state and RGB observations. Together, latent branching preserves more distinct futures, while full-set scoring improves the quality of the resulting predictive distribution.

cs.AI

UnityShots: Memory-Driven Multi-Shot Audio-Video Generation with Boundary-Aware Gating

Generating a coherent multi-shot video requires structured cross-shot memory. Subject appearance, scene context, and speaker identity must persist across cuts. Existing approaches either train end-to-end over fixed-length sequences and cannot scale, generate shot-by-shot with memory banks that grow linearly, or orchestrate pretrained generators under an LLM planner without a multi-shot-aware backbone. We present UnityShots, a memory-driven multi-shot audio-video generation system built on LTX-2.3, trained on annotated cinematic and music-video shots. The video stream maintains two fixed-size slots, a long-term memory (LTM) slot anchored to the opening shot and a short-term memory (STM) slot holding the immediately preceding tail, both updated at every cut by a boundary-conditioned gate that fuses visual cut probability and beat-tracker signals. The audio stream injects a reference speaker token at every shot to preserve vocal timbre without a sliding audio bank. A discrete cut-type prior, learned through AdaLN, becomes an inference-time control knob over transition strength. We release a benchmark of $200$ multi-cultural multi-shot sequences spanning six ethnic regions and ten or more languages, with per-shot reference identities, reference audio, and per-boundary transition labels. Evaluated across I2V, T2V, and R2V conditioning modes, UnityShots leads open-source baselines on every cross-shot coherence metric and matches the strongest closed-source system on the multi-shot axes.

cs.CV

Aligning LLMs with Biomedical Knowledge using Balanced Fine-Tuning

Engineering LLMs to accelerate life sciences research requires a robust alignment with biomedical knowledge. We observe that biomedical text exhibits a fundamentally different uncertainty structure from general text: dense low-confidence runs encode epistemic knowledge gaps (dense causal chains, rare entities) rather than the sparse aleatoric stylistic variation typical of general text. Based on this discovery, we propose Balanced Fine-Tuning (BFT), a dual-scale post-training method that combines group-normalized token reweighting with sequence-level reallocation toward knowledge-dense samples exhibiting dense epistemic uncertainty. Across medical evaluation, biological reasoning, sparse-reward RL, and biological representation tasks, BFT provides more consistent gains than SFT and DFT under a shared training setup. When replacing the default closed-source backbones in GeneAgent (GPT-4o) and VCWorld (Gemini-2.5-Flash), the BFT-aligned 70B model delivers stronger performance across biological process reasoning and chemical perturbation prediction. Critically, all BFT variants further improve after subsequent GRPO with sparse rewards, while SFT and DFT degrade, suggesting that epistemic-aware post-training provides a more robust policy initialization. Beyond text generation, BFT-aligned LLMs produce more accurate and professional biomedical profile texts; after encoding these profiles with a text embedding model, the resulting representations support gene-level, cell-level, and perturbation-response tasks, suggesting that BFT-enhanced generation can facilitate biological representation and, in turn, broader biomedical downstream tasks.

cs.LG

Controllable Layer Decomposition for Reversible Multi-Layer Image Generation

This work presents Controllable Layer Decomposition (CLD), a method for achieving fine-grained and controllable multi-layer separation of raster images. In practical workflows, designers typically generate and edit each RGBA layer independently before compositing them into a final raster image. However, this process is irreversible: once composited, layer-level editing is no longer possible. Existing methods commonly rely on image matting and inpainting, but remain limited in controllability and segmentation precision. To address these challenges, we propose two key modules: LayerDecompose-DiT (LD-DiT), which decouples image elements into distinct layers and enables fine-grained control; and Multi-Layer Conditional Adapter (MLCA), which injects target image information into multi-layer tokens to achieve precise conditional generation. To enable a comprehensive evaluation, we build a new benchmark and introduce tailored evaluation metrics. Experimental results show that CLD consistently outperforms existing methods in both decomposition quality and controllability. Furthermore, the separated layers produced by CLD can be directly manipulated in commonly used design tools such as PowerPoint, highlighting its practical value and applicability in real-world creative workflows. Our project is available at https://monkek123king.github.io/CLD_page/.

cs.GR

ConsistentID: Portrait Generation with Multimodal Fine-Grained Identity Preserving

Diffusion-based technologies have made significant strides, particularly in personalized and customized facialgeneration. However, existing methods face challenges in achieving high-fidelity and detailed identity (ID)consistency, primarily due to insufficient fine-grained control over facial areas and the lack of a comprehensive strategy for ID preservation by fully considering intricate facial details and the overall face. To address these limitations, we introduce ConsistentID, an innovative method crafted for diverseidentity-preserving portrait generation under fine-grained multimodal facial prompts, utilizing only a single reference image. ConsistentID comprises two key components: a multimodal facial prompt generator that combines facial features, corresponding facial descriptions and the overall facial context to enhance precision in facial details, and an ID-preservation network optimized through the facial attention localization strategy, aimed at preserving ID consistency in facial regions. Together, these components significantly enhance the accuracy of ID preservation by introducing fine-grained multimodal ID information from facial regions. To facilitate training of ConsistentID, we present a fine-grained portrait dataset, FGID, with over 500,000 facial images, offering greater diversity and comprehensiveness than existing public facial datasets. % such as LAION-Face, CelebA, FFHQ, and SFHQ. Experimental results substantiate that our ConsistentID achieves exceptional precision and diversity in personalized facial generation, surpassing existing methods in the MyStyle dataset. Furthermore, while ConsistentID introduces more multimodal ID information, it maintains a fast inference speed during generation.

cs.CV

Multimodal Identification of Alzheimer's Disease: A Review

Alzheimer's disease is a progressive neurological disorder characterized by cognitive impairment and memory loss. With the increasing aging population, the incidence of AD is continuously rising, making early diagnosis and intervention an urgent need. In recent years, a considerable number of teams have applied computer-aided diagnostic techniques to early classification research of AD. Most studies have utilized imaging modalities such as magnetic resonance imaging (MRI), positron emission tomography (PET), and electroencephalogram (EEG). However, there have also been studies that attempted to use other modalities as input features for the models, such as sound, posture, biomarkers, cognitive assessment scores, and their fusion. Experimental results have shown that the combination of multiple modalities often leads to better performance compared to a single modality. Therefore, this paper will focus on different modalities and their fusion, thoroughly elucidate the mechanisms of various modalities, explore which methods should be combined to better harness their utility, analyze and summarize the literature in the field of early classification of AD in recent years, in order to explore more possibilities of modality combinations.

eess.IV