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Zhenwei Shi

Publications and source records attributed to Zhenwei Shi.

102 records · Page 6Linked to original sources

WSSS4LUAD: Grand Challenge on Weakly-supervised Tissue Semantic Segmentation for Lung Adenocarcinoma

Lung cancer is the leading cause of cancer death worldwide, and adenocarcinoma (LUAD) is the most common subtype. Exploiting the potential value of the histopathology images can promote precision medicine in oncology. Tissue segmentation is the basic upstream task of histopathology image analysis. Existing deep learning models have achieved superior segmentation performance but require sufficient pixel-level annotations, which is time-consuming and expensive. To enrich the label resources of LUAD and to alleviate the annotation efforts, we organize this challenge WSSS4LUAD to call for the outstanding weakly-supervised semantic segmentation (WSSS) techniques for histopathology images of LUAD. Participants have to design the algorithm to segment tumor epithelial, tumor-associated stroma and normal tissue with only patch-level labels. This challenge includes 10,091 patch-level annotations (the training set) and over 130 million labeled pixels (the validation and test sets), from 87 WSIs (67 from GDPH, 20 from TCGA). All the labels were generated by a pathologist-in-the-loop pipeline with the help of AI models and checked by the label review board. Among 532 registrations, 28 teams submitted the results in the test phase with over 1,000 submissions. Finally, the first place team achieved mIoU of 0.8413 (tumor: 0.8389, stroma: 0.7931, normal: 0.8919). According to the technical reports of the top-tier teams, CAM is still the most popular approach in WSSS. Cutmix data augmentation has been widely adopted to generate more reliable samples. With the success of this challenge, we believe that WSSS approaches with patch-level annotations can be a complement to the traditional pixel annotations while reducing the annotation efforts. The entire dataset has been released to encourage more researches on computational pathology in LUAD and more novel WSSS techniques.

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Dual-Branched Spatio-temporal Fusion Network for Multi-horizon Tropical Cyclone Track Forecast

Tropical cyclone (TC) is an extreme tropical weather system and its trajectory can be described by a variety of spatio-temporal data. Effective mining of these data is the key to accurate TCs track forecasting. However, existing methods face the problem that the model complexity is too high or it is difficult to efficiently extract features from multi-modal data. In this paper, we propose the Dual-Branched spatio-temporal Fusion Network (DBF-Net) -- a novel multi-horizon tropical cyclone track forecasting model which fuses the multi-modal features efficiently. DBF-Net contains a TC features branch that extracts temporal features from 1D inherent features of TCs and a pressure field branch that extracts spatio-temporal features from reanalysis 2D pressure field. Through the encoder-decoder-based architecture and efficient feature fusion, DBF-Net can fully mine the information of the two types of data, and achieve good TCs track prediction results. Extensive experiments on historical TCs track data in the Northwest Pacific show that our DBF-Net achieves significant improvement compared with existing statistical and deep learning TCs track forecast methods.

cs.LG↗

Lung Cancer Diagnosis Using Deep Attention Based on Multiple Instance Learning and Radiomics

Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification problem, which does not reflect clinical practice, where clinicians diagnose a patient based on a set of images of nodules, instead of one specific nodule. Besides, the low interpretability of the output provided by these methods presents an important barrier for their adoption. In this article, we treat lung cancer diagnosis as a multiple instance learning (MIL) problem in order to better reflect the diagnosis process in the clinical setting and for the higher interpretability of the output. We chose radiomics as the source of input features and deep attention-based MIL as the classification algorithm.The attention mechanism provides higher interpretability by estimating the importance of each instance in the set for the final diagnosis.In order to improve the model's performance in a small imbalanced dataset, we introduce a new bag simulation method for MIL.The results show that our method can achieve a mean accuracy of 0.807 with a standard error of the mean (SEM) of 0.069, a recall of 0.870 (SEM 0.061), a positive predictive value of 0.928 (SEM 0.078), a negative predictive value of 0.591 (SEM 0.155) and an area under the curve (AUC) of 0.842 (SEM 0.074), outperforming other MIL methods.Additional experiments show that the proposed oversampling strategy significantly improves the model's performance. In addition, our experiments show that our method provides an indication of the importance of each nodule in determining the diagnosis, which combined with the well-defined radiomic features, make the results more interpretable and acceptable for doctors and patients.

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Semantic decoupled representation learning for remote sensing image change detection

Contemporary transfer learning-based methods to alleviate the data insufficiency in change detection (CD) are mainly based on ImageNet pre-training. Self-supervised learning (SSL) has recently been introduced to remote sensing (RS) for learning in-domain representations. Here, we propose a semantic decoupled representation learning for RS image CD. Typically, the object of interest (e.g., building) is relatively small compared to the vast background. Different from existing methods expressing an image into one representation vector that may be dominated by irrelevant land-covers, we disentangle representations of different semantic regions by leveraging the semantic mask. We additionally force the model to distinguish different semantic representations, which benefits the recognition of objects of interest in the downstream CD task. We construct a dataset of bitemporal images with semantic masks in an effortless manner for pre-training. Experiments on two CD datasets show our model outperforms ImageNet pre-training, in-domain supervised pre-training, and several recent SSL methods.

cs.CV↗

Feedback Refined Local-Global Network for Super-Resolution of Hyperspectral Imagery

With the development of deep learning technology, multi-spectral image super-resolution methods based on convolutional neural network have recently achieved great progress. However, the single hyperspectral image super-resolution remains a challenging problem due to the high-dimensional and complex spectral characteristics of hyperspectral data, which make it difficult to simultaneously capture spatial and spectral information. To deal with this issue, we propose a novel Feedback Refined Local-Global Network (FRLGN) for the super-resolution of hyperspectral image. To be specific, we develop a new Feedback Structure and a Local-Global Spectral Block to alleviate the difficulty in spatial and spectral feature extraction. The Feedback Structure can transfer the high-level information to guide the generation process of low-level feature, which is achieved by a recurrent structure with finite unfoldings. Furthermore, in order to effectively use the high-level information passed back, a Local-Global Spectral Block is constructed to handle the feedback connections. The Local-Global Spectral Block utilizes the feedback high-level information to correct the low-level feature from local spectral bands and generates powerful high-level representations among global spectral bands. By incorporating the Feedback Structure and Local-Global Spectral Block, the FRLGN can fully exploit spatial-spectral correlations among spectral bands and gradually reconstruct high-resolution hyperspectral images. The source code of FRLGN is available at https://github.com/tangzhenjie/FRLGN.

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PDBL: Improving Histopathological Tissue Classification with Plug-and-Play Pyramidal Deep-Broad Learning

Histopathological tissue classification is a fundamental task in pathomics cancer research. Precisely differentiating different tissue types is a benefit for the downstream researches, like cancer diagnosis, prognosis and etc. Existing works mostly leverage the popular classification backbones in computer vision to achieve histopathological tissue classification. In this paper, we proposed a super lightweight plug-and-play module, named Pyramidal Deep-Broad Learning (PDBL), for any well-trained classification backbone to further improve the classification performance without a re-training burden. We mimic how pathologists observe pathology slides in different magnifications and construct an image pyramid for the input image in order to obtain the pyramidal contextual information. For each level in the pyramid, we extract the multi-scale deep-broad features by our proposed Deep-Broad block (DB-block). We equipped PDBL in three popular classification backbones, ShuffLeNetV2, EfficientNetb0, and ResNet50 to evaluate the effectiveness and efficiency of our proposed module on two datasets (Kather Multiclass Dataset and the LC25000 Dataset). Experimental results demonstrate the proposed PDBL can steadily improve the tissue-level classification performance for any CNN backbones, especially for the lightweight models when given a small among of training samples (less than 10%), which greatly saves the computational time and annotation efforts.

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Multi-Layer Pseudo-Supervision for Histopathology Tissue Semantic Segmentation using Patch-level Classification Labels

Tissue-level semantic segmentation is a vital step in computational pathology. Fully-supervised models have already achieved outstanding performance with dense pixel-level annotations. However, drawing such labels on the giga-pixel whole slide images is extremely expensive and time-consuming. In this paper, we use only patch-level classification labels to achieve tissue semantic segmentation on histopathology images, finally reducing the annotation efforts. We proposed a two-step model including a classification and a segmentation phases. In the classification phase, we proposed a CAM-based model to generate pseudo masks by patch-level labels. In the segmentation phase, we achieved tissue semantic segmentation by our proposed Multi-Layer Pseudo-Supervision. Several technical novelties have been proposed to reduce the information gap between pixel-level and patch-level annotations. As a part of this paper, we introduced a new weakly-supervised semantic segmentation (WSSS) dataset for lung adenocarcinoma (LUAD-HistoSeg). We conducted several experiments to evaluate our proposed model on two datasets. Our proposed model outperforms two state-of-the-art WSSS approaches. Note that we can achieve comparable quantitative and qualitative results with the fully-supervised model, with only around a 2\% gap for MIoU and FwIoU. By comparing with manual labeling, our model can greatly save the annotation time from hours to minutes. The source code is available at: \url{https://github.com/ChuHan89/WSSS-Tissue}.

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Geographical Knowledge-driven Representation Learning for Remote Sensing Images

The proliferation of remote sensing satellites has resulted in a massive amount of remote sensing images. However, due to human and material resource constraints, the vast majority of remote sensing images remain unlabeled. As a result, it cannot be applied to currently available deep learning methods. To fully utilize the remaining unlabeled images, we propose a Geographical Knowledge-driven Representation learning method for remote sensing images (GeoKR), improving network performance and reduce the demand for annotated data. The global land cover products and geographical location associated with each remote sensing image are regarded as geographical knowledge to provide supervision for representation learning and network pre-training. An efficient pre-training framework is proposed to eliminate the supervision noises caused by imaging times and resolutions difference between remote sensing images and geographical knowledge. A large scale pre-training dataset Levir-KR is proposed to support network pre-training. It contains 1,431,950 remote sensing images from Gaofen series satellites with various resolutions. Experimental results demonstrate that our proposed method outperforms ImageNet pre-training and self-supervised representation learning methods and significantly reduces the burden of data annotation on downstream tasks such as scene classification, semantic segmentation, object detection, and cloud / snow detection. It demonstrates that our proposed method can be used as a novel paradigm for pre-training neural networks. Codes will be available on https://github.com/flyakon/Geographical-Knowledge-driven-Representaion-Learning.

cs.CV↗

Remote Sensing Image Change Detection with Transformers

Modern change detection (CD) has achieved remarkable success by the powerful discriminative ability of deep convolutions. However, high-resolution remote sensing CD remains challenging due to the complexity of objects in the scene. Objects with the same semantic concept may show distinct spectral characteristics at different times and spatial locations. Most recent CD pipelines using pure convolutions are still struggling to relate long-range concepts in space-time. Non-local self-attention approaches show promising performance via modeling dense relations among pixels, yet are computationally inefficient. Here, we propose a bitemporal image transformer (BIT) to efficiently and effectively model contexts within the spatial-temporal domain. Our intuition is that the high-level concepts of the change of interest can be represented by a few visual words, i.e., semantic tokens. To achieve this, we express the bitemporal image into a few tokens, and use a transformer encoder to model contexts in the compact token-based space-time. The learned context-rich tokens are then feedback to the pixel-space for refining the original features via a transformer decoder. We incorporate BIT in a deep feature differencing-based CD framework. Extensive experiments on three CD datasets demonstrate the effectiveness and efficiency of the proposed method. Notably, our BIT-based model significantly outperforms the purely convolutional baseline using only 3 times lower computational costs and model parameters. Based on a naive backbone (ResNet18) without sophisticated structures (e.g., FPN, UNet), our model surpasses several state-of-the-art CD methods, including better than four recent attention-based methods in terms of efficiency and accuracy. Our code is available at https://github.com/justchenhao/BIT\_CD.

cs.CV↗

NeuralMagicEye: Learning to See and Understand the Scene Behind an Autostereogram

An autostereogram, a.k.a. magic eye image, is a single-image stereogram that can create visual illusions of 3D scenes from 2D textures. This paper studies an interesting question that whether a deep CNN can be trained to recover the depth behind an autostereogram and understand its content. The key to the autostereogram magic lies in the stereopsis - to solve such a problem, a model has to learn to discover and estimate disparity from the quasi-periodic textures. We show that deep CNNs embedded with disparity convolution, a novel convolutional layer proposed in this paper that simulates stereopsis and encodes disparity, can nicely solve such a problem after being sufficiently trained on a large 3D object dataset in a self-supervised fashion. We refer to our method as ``NeuralMagicEye''. Experiments show that our method can accurately recover the depth behind autostereograms with rich details and gradient smoothness. Experiments also show the completely different working mechanisms for autostereogram perception between neural networks and human eyes. We hope this research can help people with visual impairments and those who have trouble viewing autostereograms. Our code is available at \url{https://jiupinjia.github.io/neuralmagiceye/}.

cs.CV↗

Stylized Neural Painting

This paper proposes an image-to-painting translation method that generates vivid and realistic painting artworks with controllable styles. Different from previous image-to-image translation methods that formulate the translation as pixel-wise prediction, we deal with such an artistic creation process in a vectorized environment and produce a sequence of physically meaningful stroke parameters that can be further used for rendering. Since a typical vector render is not differentiable, we design a novel neural renderer which imitates the behavior of the vector renderer and then frame the stroke prediction as a parameter searching process that maximizes the similarity between the input and the rendering output. We explored the zero-gradient problem on parameter searching and propose to solve this problem from an optimal transportation perspective. We also show that previous neural renderers have a parameter coupling problem and we re-design the rendering network with a rasterization network and a shading network that better handles the disentanglement of shape and color. Experiments show that the paintings generated by our method have a high degree of fidelity in both global appearance and local textures. Our method can be also jointly optimized with neural style transfer that further transfers visual style from other images. Our code and animated results are available at \url{https://jiupinjia.github.io/neuralpainter/}.

cs.CV↗

Face-to-Parameter Translation for Game Character Auto-Creation

Character customization system is an important component in Role-Playing Games (RPGs), where players are allowed to edit the facial appearance of their in-game characters with their own preferences rather than using default templates. This paper proposes a method for automatically creating in-game characters of players according to an input face photo. We formulate the above "artistic creation" process under a facial similarity measurement and parameter searching paradigm by solving an optimization problem over a large set of physically meaningful facial parameters. To effectively minimize the distance between the created face and the real one, two loss functions, i.e. a "discriminative loss" and a "facial content loss", are specifically designed. As the rendering process of a game engine is not differentiable, a generative network is further introduced as an "imitator" to imitate the physical behavior of the game engine so that the proposed method can be implemented under a neural style transfer framework and the parameters can be optimized by gradient descent. Experimental results demonstrate that our method achieves a high degree of generation similarity between the input face photo and the created in-game character in terms of both global appearance and local details. Our method has been deployed in a new game last year and has now been used by players over 1 million times.

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