arXiv subjects

Zhenxing Xu

Publications and source records attributed to Zhenxing Xu.

7 recordsLinked to original sources

arXiv2026

Fly0: Persistent Metric Anchoring for Zero-Shot Aerial Vision-Language Navigation

Current Visual-Language Navigation (VLN) methodologies face a trade-off between semantic understanding and control precision. While Multimodal Large Language Models (MLLMs) offer superior reasoning, deploying them as low-level controllers leads to high latency, trajectory oscillations, and poor generalization due to weak geometric grounding. To address these limitations, we propose Fly0, a framework that decouples semantic reasoning from geometric planning. The proposed method operates through a three-stage pipeline: (1) an MLLM-driven module for grounding natural language instructions into 2D pixel coordinates; (2) a geometric projection module that utilizes depth data to localize targets in 3D space; and (3) a geometric planner that generates collision-free trajectories. This mechanism enables robust navigation even when visual contact is lost. By eliminating the need for continuous inference, Fly0 reduces computational overhead and improves system stability. Extensive experiments in simulation and real-world environments demonstrate that Fly0 outperforms state-of-the-art baselines, improving the Success Rate by over 20\% and reducing Navigation Error (NE) by approximately 50\% in unstructured environments. Our code is available at https://github.com/xuzhenxing1/Fly0.

cs.RO↗

arXiv2026

Rethinking Efficiency in Neural Combinatorial Optimization: Batched Preference Optimization with Mamba

We study efficiency as a first-class objective in Neural Combinatorial Optimization (NCO) and present ECO, an efficient learning framework that combines batched preference optimization with a Mamba backbone. Instead of tightly interleaving every policy update with on-policy rollouts, ECO decouples trajectory generation from gradient updates through two stages: supervised warm-up on pre-computed solutions and iterative Direct Preference Optimization (DPO) on batched candidate sets generated by the current policy. We pair this learning pipeline with a mixed Mamba encoder-decoder that reduces memory growth on long sequences and improves hardware utilization. A local-search-guided bootstrapping strategy is further used during training to widen preference margins and stabilize iterative improvement. Importantly, local search is only used to construct stronger preference pairs during training and is never invoked at inference time. On TSP and CVRP, ECO achieves the strongest overall performance among the compared neural baselines while also delivering clear advantages in memory usage and throughput. We provide additional analysis on memory scaling, throughput, and the contribution of each design component.

cs.LG↗

arXiv2026

AutoEP: LLMs-Driven Automation of Hyperparameter Evolution for Metaheuristic Algorithms

Dynamically configuring algorithm hyperparameters is a fundamental challenge in computational intelligence. While learning-based methods offer automation, they suffer from prohibitive sample complexity and poor generalization. We introduce AutoEP, a novel framework that bypasses training entirely by leveraging Large Language Models (LLMs) as zero-shot reasoning engines for algorithm control. AutoEP's core innovation lies in a tight synergy between two components: (1) an online Exploratory Landscape Analysis (ELA) module that provides real-time, quantitative feedback on the search dynamics, and (2) a multi-LLM reasoning chain that interprets this feedback to generate adaptive hyperparameter strategies. This approach grounds high-level reasoning in empirical data, mitigating hallucination. Evaluated on three distinct metaheuristics across diverse combinatorial optimization benchmarks, AutoEP consistently outperforms state-of-the-art tuners, including neural evolution and other LLM-based methods. Notably, our framework enables open-source models like Qwen3-30B to match the performance of GPT-4, demonstrating a powerful and accessible new paradigm for automated hyperparameter design. Our code is available at https://github.com/YiZheZhang12/AutoEP.

cs.AI↗

arXiv2025

TrialCompass: Visual Analytics for Enhancing the Eligibility Criteria Design of Clinical Trials

Eligibility criteria play a critical role in clinical trials by determining the target patient population, which significantly influences the outcomes of medical interventions. However, current approaches for designing eligibility criteria have limitations to support interactive exploration of the large space of eligibility criteria. They also ignore incorporating detailed characteristics from the original electronic health record (EHR) data for criteria refinement. To address these limitations, we proposed TrialCompass, a visual analytics system integrating a novel workflow, which can empower clinicians to iteratively explore the vast space of eligibility criteria through knowledge-driven and outcome-driven approaches. TrialCompass supports history-tracking to help clinicians trace the evolution of their adjustments and decisions when exploring various forms of data (i.e., eligibility criteria, outcome metrics, and detailed characteristics of original EHR data) through these two approaches. This feature can help clinicians comprehend the impact of eligibility criteria on outcome metrics and patient characteristics, which facilitates systematic refinement of eligibility criteria. Using a real-world dataset, we demonstrated the effectiveness of TrialCompass in providing insights into designing eligibility criteria for septic shock and sepsis-associated acute kidney injury. We also discussed the research prospects of applying visual analytics to clinical trials.

cs.HC↗

arXiv2022

Multimodal Machine Learning in Precision Health

As machine learning and artificial intelligence are more frequently being leveraged to tackle problems in the health sector, there has been increased interest in utilizing them in clinical decision-support. This has historically been the case in single modal data such as electronic health record data. Attempts to improve prediction and resemble the multimodal nature of clinical expert decision-making this has been met in the computational field of machine learning by a fusion of disparate data. This review was conducted to summarize this field and identify topics ripe for future research. We conducted this review in accordance with the PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) extension for Scoping Reviews to characterize multi-modal data fusion in health. We used a combination of content analysis and literature searches to establish search strings and databases of PubMed, Google Scholar, and IEEEXplore from 2011 to 2021. A final set of 125 articles were included in the analysis. The most common health areas utilizing multi-modal methods were neurology and oncology. However, there exist a wide breadth of current applications. The most common form of information fusion was early fusion. Notably, there was an improvement in predictive performance performing heterogeneous data fusion. Lacking from the papers were clear clinical deployment strategies and pursuit of FDA-approved tools. These findings provide a map of the current literature on multimodal data fusion as applied to health diagnosis/prognosis problems. Multi-modal machine learning, while more robust in its estimations over unimodal methods, has drawbacks in its scalability and the time-consuming nature of information concatenation.

cs.LG↗

arXiv2019

Identifying Sub-Phenotypes of Acute Kidney Injury using Structured and Unstructured Electronic Health Record Data with Memory Networks

Acute Kidney Injury (AKI) is a common clinical syndrome characterized by the rapid loss of kidney excretory function, which aggravates the clinical severity of other diseases in a large number of hospitalized patients. Accurate early prediction of AKI can enable in-time interventions and treatments. However, AKI is highly heterogeneous, thus identification of AKI sub-phenotypes can lead to an improved understanding of the disease pathophysiology and development of more targeted clinical interventions. This study used a memory network-based deep learning approach to discover AKI sub-phenotypes using structured and unstructured electronic health record (EHR) data of patients before AKI diagnosis. We leveraged a real world critical care EHR corpus including 37,486 ICU stays. Our approach identified three distinct sub-phenotypes: sub-phenotype I is with an average age of 63.03$ \pm 17.25 $ years, and is characterized by mild loss of kidney excretory function (Serum Creatinine (SCr) $1.55\pm 0.34$ mg/dL, estimated Glomerular Filtration Rate Test (eGFR) $107.65\pm 54.98$ mL/min/1.73$m^2$). These patients are more likely to develop stage I AKI. Sub-phenotype II is with average age 66.81$ \pm 10.43 $ years, and was characterized by severe loss of kidney excretory function (SCr $1.96\pm 0.49$ mg/dL, eGFR $82.19\pm 55.92$ mL/min/1.73$m^2$). These patients are more likely to develop stage III AKI. Sub-phenotype III is with average age 65.07$ \pm 11.32 $ years, and was characterized moderate loss of kidney excretory function and thus more likely to develop stage II AKI (SCr $1.69\pm 0.32$ mg/dL, eGFR $93.97\pm 56.53$ mL/min/1.73$m^2$). Both SCr and eGFR are significantly different across the three sub-phenotypes with statistical testing plus postdoc analysis, and the conclusion still holds after age adjustment.

cs.LG↗

arXiv2019

Evaluating the Portability of an NLP System for Processing Echocardiograms: A Retrospective, Multi-site Observational Study

While natural language processing (NLP) of unstructured clinical narratives holds the potential for patient care and clinical research, portability of NLP approaches across multiple sites remains a major challenge. This study investigated the portability of an NLP system developed initially at the Department of Veterans Affairs (VA) to extract 27 key cardiac concepts from free-text or semi-structured echocardiograms from three academic medical centers: Weill Cornell Medicine, Mayo Clinic and Northwestern Medicine. While the NLP system showed high precision and recall measurements for four target concepts (aortic valve regurgitation, left atrium size at end systole, mitral valve regurgitation, tricuspid valve regurgitation) across all sites, we found moderate or poor results for the remaining concepts and the NLP system performance varied between individual sites.

cs.CL↗