arXiv subjects

Zhidong Cao

Publications and source records attributed to Zhidong Cao.

5 recordsLinked to original sources

arXiv2026

DongYuan: An LLM-Based Framework for Integrative Chinese and Western Medicine Spleen-Stomach Disorders Diagnosis

The clinical burden of spleen-stomach disorders is substantial. While large language models (LLMs) offer new potential for medical applications, they face three major challenges in the context of integrative Chinese and Western medicine (ICWM): a lack of high-quality data, the absence of models capable of effectively integrating the reasoning logic of traditional Chinese medicine (TCM) syndrome differentiation with that of Western medical (WM) disease diagnosis, and the shortage of a standardized evaluation benchmark. To address these interrelated challenges, we propose DongYuan, an ICWM spleen-stomach diagnostic framework. Specifically, three ICWM datasets (SSDF-Syndrome, SSDF-Dialogue, and SSDF-PD) were curated to fill the gap in high-quality data for spleen-stomach disorders. We then developed SSDF-Core, a core diagnostic LLM that acquires robust ICWM reasoning capabilities through a two-stage training regimen of supervised fine-tuning. tuning (SFT) and direct preference optimization (DPO), and complemented it with SSDF-Navigator, a pluggable consultation navigation model designed to optimize clinical inquiry strategies. Additionally, we established SSDF-Bench, a comprehensive evaluation benchmark focused on ICWM diagnosis of spleen-stomach disorders. Experimental results demonstrate that SSDF-Core significantly outperforms 12 mainstream baselines on SSDF-Bench. DongYuan lays a solid methodological foundation and provides practical technical references for the future development of intelligent ICWM diagnostic systems.

cs.CL↗

arXiv2021

Impacts of export restrictions on the global personal protective equipment trade network during COVID-19

The COVID-19 pandemic has caused a dramatic surge in demand for personal protective equipment (PPE) worldwide. Many countries have imposed export restrictions on PPE to ensure the sufficient domestic supply. The surging demand and export restrictions cause shortage contagions on the global PPE trade network. Here, we develop an integrated network model, which integrates a metapopulation model and a threshold model, to investigate the shortage contagion patterns. The metapopulation model captures disease contagion across countries. The threshold model captures the shortage contagion on the global PPE trade network. Results show that, the shortage contagion patterns are mainly decided by top exporters. Export restrictions exacerbate the shortages of PPE and cause the shortage contagion to transmit even faster than the disease contagion. Besides, export restrictions lead to ineffective and inefficient allocation of PPE around the world, which has no benefits for the world to fight against the pandemic.

physics.soc-ph↗

arXiv2020

Optimal vaccination program for two infectious diseases with cross immunity

There are often multiple diseases with cross immunity competing for vaccination resources. Here we investigate the optimal vaccination program in a two-layer Susceptible-Infected-Removed (SIR) model, where two diseases with cross immunity spread in the same population, and vaccines for both diseases are available. We identify three scenarios of the optimal vaccination program, which prevents the outbreaks of both diseases at the minimum cost. We analytically derive a criterion to specify the optimal program based on the costs for different vaccines.

q-bio.PE↗

arXiv2020

Effect of heterogeneous risk perception on information diffusion, behavior change, and disease transmission

Motivated by the importance of individual differences in risk perception and behavior change in people's responses to infectious disease outbreaks (particularly the ongoing COVID-19 pandemic), we propose a heterogeneous Disease-Behavior-Information (hDBI) transmission model, in which people's risk of getting infected is influenced by information diffusion, behavior change, and disease transmission. We use both a mean-field approximation and Monte Carlo simulations to analyze the dynamics of the model. Information diffusion influences behavior change by allowing people to be aware of the disease and adopt self-protection, and subsequently affects disease transmission by changing the actual infection rate. Results show that (a) awareness plays a central role in epidemic prevention; (b) a reasonable fraction of "over-reacting" nodes are needed in epidemic prevention; (c) R0 has different effects on epidemic outbreak for cases with and without asymptomatic infection; (d) social influence on behavior change can remarkably decrease the epidemic outbreak size. This research indicates that the media and opinion leaders should not understate the transmissibility and severity of diseases to ensure that people could become aware of the disease and adopt self-protection to protect themselves and the whole population.

physics.soc-ph↗

arXiv2018

Flexible Attributed Network Embedding

Network embedding aims to find a way to encode network by learning an embedding vector for each node in the network. The network often has property information which is highly informative with respect to the node's position and role in the network. Most network embedding methods fail to utilize this information during network representation learning. In this paper, we propose a novel framework, FANE, to integrate structure and property information in the network embedding process. In FANE, we design a network to unify heterogeneity of the two information sources, and define a new random walking strategy to leverage property information and make the two information compensate. FANE is conceptually simple and empirically powerful. It improves over the state-of-the-art methods on Cora dataset classification task by over 5%, more than 10% on WebKB dataset classification task. Experiments also show that the results improve more than the state-of-the-art methods as increasing training size. Moreover, qualitative visualization show that our framework is helpful in network property information exploration. In all, we present a new way for efficiently learning state-of-the-art task-independent representations in complex attributed networks. The source code and datasets of this paper can be obtained from https://github.com/GraphWorld/FANE.

cs.SI↗