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Zhihong Zhu

Publications and source records attributed to Zhihong Zhu.

At least 19 recordsLinked to original sources

RAGCell: Retrieval-Augmented Generation as Supervision for Versatile Single-cell Analysis

Single-cell foundation models (scFMs) are transforming computational biology by enabling generalizable, task-agnostic representations for versatile single-cell analysis. Despite their progress in facilitating rapid deployment for downstream tasks, off-the-shelf scFMs still have some overlooked concerns: (I) (Pretraining Cost.) Pretrain-based scFMs necessitate pretraining on a vast volume of cells, rendering it draining resources in applications. (II) (Heterogeneous Gap.) Large Language Models (LLM)-based scFMs ignore the tremendous heterogeneous gap between LLM textual and raw cellular spaces, leading to insufficient capability when facing downstream tasks. To this end, we introduce RAGCell, a versatile single-cell analysis framework that achieves a double-win in both cost-effectiveness and high performance. The success of RAGCell lies in two key aspects: Leveraging LLMs to construct cell-level and feature-level knowledge databases, which serve as supervision signals for training the cell model and significantly reduce the training cost ($>$pretrain-based scFMs). Aligning cell representations with text embeddings from the bi-level knowledge databases, enabling knowledge transfer from textual spaces to cellular spaces and effectively mitigating the heterogeneous gap ($>$LLM-based scFMs). Through extensive experiments on six downstream single-cell analysis tasks, we demonstrate that RAGCell achieves outstanding performance compared to state-of-the-art scFMs while operating at less than $\sim$1/10 the cost of pretrain-based scFMs.

q-bio.GN↗

ReflectRL: Learning from Golden Negative Trajectories via Reflective-to-Direct Reasoning

On-policy training has emerged as a powerful post-training paradigm for improving the reasoning capabilities of large language models, and is often enhanced by golden trajectories from stronger expert models. However, when the expert fails on harder problems, existing trajectory-guided methods lose their main source of supervision, and these failed trajectories are typically discarded as negative samples. We argue that such failures, which we call Golden Negative Trajectories, can still provide valuable reasoning signals when treated not as demonstrations to imitate, but as flawed trajectories to reflect upon. We identify a Reflection Advantage: for hard problems, reflecting on a flawed trajectory can be easier and more effective than solving the problem directly from scratch. Motivated by this, we propose ReflectRL, a lightweight plug-and-play framework that learns from Golden Negative Trajectories during on-policy training. ReflectRL first uses these trajectories to elicit Reflective Reasoning, then applies Reflective-to-Direct Policy Transition to transfer the acquired reasoning behavior back to Direct Reasoning. Experiments across 9 benchmarks, 4 LLM backbones, and 4 on-policy training methods show that ReflectRL consistently improves reasoning performance with minimal overhead.

cs.AI↗

Orchestra-o1: Omnimodal Agent Orchestration

The recent success of agent swarms has shifted the paradigm of large language model (LLM)-based agents from single-agent workflows to multi-agent systems, highlighting the importance of agent orchestration for task decomposition and collaboration. However, existing orchestration frameworks are limited to a narrow set of modalities and struggle to generalize to more complex settings where heterogeneous modalities coexist and interact. This limitation becomes particularly pronounced in omnimodal scenarios, where tasks require the unified understanding and coordination of diverse inputs such as text, image, audio, and video. In this work, we propose Orchestra-o1, an omnimodal agent orchestration framework designed to support efficient agent collaboration across multiple modalities. Orchestra-o1 introduces a unified orchestration mechanism that enables modality-aware task decomposition, online sub-agent specialization, and parallel sub-task execution. This scalable design allows agent systems to effectively tackle complex real-world tasks involving heterogeneous information sources, surpassing the second-best approach by 10.3% accuracy on the OmniGAIA benchmark. Furthermore, we introduce decision-aligned group relative policy optimization (DA-GRPO), an efficient agentic reinforcement learning approach for training Orchestra-o1-8B, which also achieves state-of-the-art performance against all existing open-source omnimodal agents.

cs.AI↗

MMErroR: A Benchmark for Erroneous Reasoning in Vision-Language Models

Recent advances in Vision-Language Models (VLMs) have improved performance in multi-modal learning, raising the question of whether these models truly understand the content they process. Crucially, can VLMs detect when a reasoning process is wrong and identify its error type? To answer this, we present MMErroR, a multi-modal benchmark of 1997 samples, each embedding a single coherent reasoning error. These samples span 24 subdomains across six top-level domains, ensuring broad coverage and taxonomic richness. Unlike existing benchmarks that focus on answer correctness, MMErroR targets a process-level, error-centric evaluation that requires models to detect incorrect reasoning and classify the error type within both visual and linguistic contexts. We evaluate 12 representative VLMs, and even the best model, Gemini-3-Pro-Preview, classifies the error correctly in only 66.65\% of cases, underscoring the challenge of identifying erroneous reasoning. Furthermore, the ability to accurately identify errors offers valuable insights into the capabilities of multi-modal models. Project Page: https://mmerror-benchmark.github.io

cs.CV↗

Recent Advances in Multimodal Affective Computing: An NLP Perspective

Multimodal affective computing has gained increasing attention due to its broad applications in understanding human behavior and intentions, particularly in text-centric multimodal scenarios. Existing research spans diverse tasks, modalities, and modeling paradigms, yet lacks a unified perspective. In this survey, we systematically review recent advances from an NLP perspective, focusing on four representative tasks: multimodal sentiment analysis (MSA), multimodal emotion recognition in conversation (MERC), multimodal aspect-based sentiment analysis (MABSA), and multimodal multi-label emotion recognition (MMER). We present a unified view by comparing task formulations, benchmark datasets, and evaluation protocols, and by organizing representative methods into key paradigms, including multitask learning, pre-trained models, knowledge enhancement, and contextual modeling. We further extend the discussion to related directions, such as facial, acoustic, and physiological modalities, as well as emotion cause analysis. Finally, we highlight key challenges and outline promising future directions. To facilitate further research, we release a curated repository of relevant works and resources \footnote{https://anonymous.4open.science/r/Multimodal-Affective-Computing-Survey-9819}.

cs.CL↗

MME-Emotion: A Holistic Evaluation Benchmark for Emotional Intelligence in Multimodal Large Language Models

Recent advances in multimodal large language models (MLLMs) have catalyzed transformative progress in affective computing, enabling models to exhibit emergent emotional intelligence. Despite substantial methodological progress, current emotional benchmarks remain limited, as it is still unknown: (a) the generalization abilities of MLLMs across distinct scenarios, and (b) their reasoning capabilities to identify the triggering factors behind emotional states. To bridge these gaps, we present \textbf{MME-Emotion}, a systematic benchmark that assesses both emotional understanding and reasoning capabilities of MLLMs, enjoying \textit{scalable capacity}, \textit{diverse settings}, and \textit{unified protocols}. As the largest emotional intelligence benchmark for MLLMs, MME-Emotion contains over 6,000 curated video clips with task-specific questioning-answering (QA) pairs, spanning broad scenarios to formulate eight emotional tasks. It further incorporates a holistic evaluation suite with hybrid metrics for emotion recognition and reasoning, analyzed through a multi-agent system framework. Through a rigorous evaluation of 20 advanced MLLMs, we uncover both their strengths and limitations, yielding several key insights: \ding{182} Current MLLMs exhibit unsatisfactory emotional intelligence, with the best-performing model achieving only $39.3\%$ recognition score and $56.0\%$ Chain-of-Thought (CoT) score on our benchmark. \ding{183} Generalist models (\emph{e.g.}, Gemini-2.5-Pro) derive emotional intelligence from generalized multimodal understanding capabilities, while specialist models (\emph{e.g.}, R1-Omni) can achieve comparable performance through domain-specific post-training adaptation. By introducing MME-Emotion, we hope that it can serve as a foundation for advancing MLLMs' emotional intelligence in the future.

cs.CV↗

UPETrack: Unidirectional Position Estimation for Tracking Occluded Deformable Linear Objects

Real-time state tracking of Deformable Linear Objects (DLOs) is critical for enabling robotic manipulation of DLOs in industrial assembly, medical procedures, and daily-life applications. However, the high-dimensional configuration space, nonlinear dynamics, and frequent partial occlusions present fundamental barriers to robust real-time DLO tracking. To address these limitations, this study introduces UPETrack, a geometry-driven framework based on Unidirectional Position Estimation (UPE), which facilitates tracking without the requirement for physical modeling, virtual simulation, or visual markers. The framework operates in two phases: (1) visible segment tracking is based on a Gaussian Mixture Model (GMM) fitted via the Expectation Maximization (EM) algorithm, and (2) occlusion region prediction employing UPE algorithm we proposed. UPE leverages the geometric continuity inherent in DLO shapes and their temporal evolution patterns to derive a closed-form positional estimator through three principal mechanisms: (i) local linear combination displacement term, (ii) proximal linear constraint term, and (iii) historical curvature term. This analytical formulation allows efficient and stable estimation of occluded nodes through explicit linear combinations of geometric components, eliminating the need for additional iterative optimization. Experimental results demonstrate that UPETrack surpasses two state-of-the-art tracking algorithms, including TrackDLO and CDCPD2, in both positioning accuracy and computational efficiency.

cs.RO↗

Turb-L1: Achieving Long-term Turbulence Tracing By Tackling Spectral Bias

Accurately predicting the long-term evolution of turbulence is crucial for advancing scientific understanding and optimizing engineering applications. However, existing deep learning methods face significant bottlenecks in long-term autoregressive prediction, which exhibit excessive smoothing and fail to accurately track complex fluid dynamics. Our extensive experimental and spectral analysis of prevailing methods provides an interpretable explanation for this shortcoming, identifying Spectral Bias as the core obstacle. Concretely, spectral bias is the inherent tendency of models to favor low-frequency, smooth features while overlooking critical high-frequency details during training, thus reducing fidelity and causing physical distortions in long-term predictions. Building on this insight, we propose Turb-L1, an innovative turbulence prediction method, which utilizes a Hierarchical Dynamics Synthesis mechanism within a multi-grid architecture to explicitly overcome spectral bias. It accurately captures cross-scale interactions and preserves the fidelity of high-frequency dynamics, enabling reliable long-term tracking of turbulence evolution. Extensive experiments on the 2D turbulence benchmark show that Turb-L1 demonstrates excellent performance: (I) In long-term predictions, it reduces Mean Squared Error (MSE) by $80.3\%$ and increases Structural Similarity (SSIM) by over $9\times$ compared to the SOTA baseline, significantly improving prediction fidelity. (II) It effectively overcomes spectral bias, accurately reproducing the full enstrophy spectrum and maintaining physical realism in high-wavenumber regions, thus avoiding the spectral distortions or spurious energy accumulation seen in other methods.

cs.LG↗

Rethinking Facial Expression Recognition in the Era of Multimodal Large Language Models: Benchmark, Datasets, and Beyond

Multimodal Large Language Models (MLLMs) have revolutionized numerous research fields, including computer vision and affective computing. As a pivotal challenge in this interdisciplinary domain, facial expression recognition (FER) has evolved from separate, domain-specific models to more unified approaches. One promising avenue to unify FER tasks is converting conventional FER datasets into visual question-answering (VQA) formats, enabling the direct application of powerful generalist MLLMs for inference. However, despite the success of cutting-edge MLLMs in various tasks, their performance on FER tasks remains largely unexplored. To address this gap, we provide FERBench, a systematic benchmark that incorporates 20 state-of-the-art MLLMs across four widely used FER datasets. Our results reveal that, while MLLMs exhibit good classification performance, they still face significant limitations in reasoning and interpretability. To this end, we introduce post-training strategies aimed at enhancing the facial expression reasoning capabilities of MLLMs. Specifically, we curate two high-quality and large-scale datasets: UniFER-CoT-230K for cold-start initialization and UniFER-RLVR-360K for reinforcement learning with verifiable rewards (RLVR), respectively. Building upon them, we develop a unified and interpretable FER foundation model termed UniFER-7B, which outperforms many open-sourced and closed-source generalist MLLMs (e.g., Gemini-2.5-Pro and Qwen2.5-VL-72B).

cs.CV↗

Spatiotemporal Forecasting as Planning: A Model-Based Reinforcement Learning Approach with Generative World Models

To address the dual challenges of inherent stochasticity and non-differentiable metrics in physical spatiotemporal forecasting, we propose Spatiotemporal Forecasting as Planning (SFP), a new paradigm grounded in Model-Based Reinforcement Learning. SFP constructs a novel Generative World Model to simulate diverse, high-fidelity future states, enabling an "imagination-based" environmental simulation. Within this framework, a base forecasting model acts as an agent, guided by a beam search-based planning algorithm that leverages non-differentiable domain metrics as reward signals to explore high-return future sequences. These identified high-reward candidates then serve as pseudo-labels to continuously optimize the agent's policy through iterative self-training, significantly reducing prediction error and demonstrating exceptional performance on critical domain metrics like capturing extreme events.

cs.LG↗

Partitioner Guided Modal Learning Framework

Multimodal learning benefits from multiple modal information, and each learned modal representations can be divided into uni-modal that can be learned from uni-modal training and paired-modal features that can be learned from cross-modal interaction. Building on this perspective, we propose a partitioner-guided modal learning framework, PgM, which consists of the modal partitioner, uni-modal learner, paired-modal learner, and uni-paired modal decoder. Modal partitioner segments the learned modal representation into uni-modal and paired-modal features. Modal learner incorporates two dedicated components for uni-modal and paired-modal learning. Uni-paired modal decoder reconstructs modal representation based on uni-modal and paired-modal features. PgM offers three key benefits: 1) thorough learning of uni-modal and paired-modal features, 2) flexible distribution adjustment for uni-modal and paired-modal representations to suit diverse downstream tasks, and 3) different learning rates across modalities and partitions. Extensive experiments demonstrate the effectiveness of PgM across four multimodal tasks and further highlight its transferability to existing models. Additionally, we visualize the distribution of uni-modal and paired-modal features across modalities and tasks, offering insights into their respective contributions.

cs.CL↗

Searching for topological semi-complete bandgap in elastic truss lattices

Gapless topological phases have attracted significant interest across both quantum and classical systems owing to their novel physics and promising applications. However, the search for ideal gapless topological nodes inside a clear bandgap is still lacking in elastic systems. The degenerate points are always hidden in the trivial bulk bands due to the intricate elastic modes involved. Here, we find a topological semi-complete bandgap in a three-dimensional elastic truss lattice by tuning a supporting rod, which exhibits a complete bandgap except for the inevitable topological degenerate points. Furthermore, we experimentally map the topological semi-complete bandgap and the inside nontrivial surface state arcs with a scanning laser vibrometer. The introduced scheme provides a systematic approach for the idealization of semi-complete bandgaps and thus may significantly advance the practical utility of topological phases in mechanical engineering domains.

cond-mat.mes-hall↗

Photonic chiral bulk transports manipulated by boundary freedom in three-dimensional meta-crystals

In topological physics, one of the most intriguing phenomena is the presence of topological boundary states, accurately predicted by the well-established bulk-edge correspondence. For example, in three-dimensional Weyl semimetals, Fermi arcs emerge to connect projected Weyl points on the surface due to inheriting the bulk-edge correspondence from the integer quantum Hall effect. However, limited attention has been paid to exploring the reverse mechanism in topological crystals. In this study, we propose that boundaries can serve as an alternative degree of freedom to manipulate topological bulk transports. We analytically and experimentally validate our concept using a finite-thickness photonic meta-crystal that supports bulk nodal lines, with its zeroth modes exhibiting opposite chiral bulk transports under different boundary conditions. Notably, the mirror symmetry remains preserved across both configurations. These findings are applicable to other topological systems, providing new insights into systems with varied boundary conditions and offering the potential for the design of more compact and spatially efficient topological photonic devices.

cond-mat.mes-hall↗

XMeCap: Meme Caption Generation with Sub-Image Adaptability

Humor, deeply rooted in societal meanings and cultural details, poses a unique challenge for machines. While advances have been made in natural language processing, real-world humor often thrives in a multi-modal context, encapsulated distinctively by memes. This paper poses a particular emphasis on the impact of multi-images on meme captioning. After that, we introduce the \textsc{XMeCap} framework, a novel approach that adopts supervised fine-tuning and reinforcement learning based on an innovative reward model, which factors in both global and local similarities between visuals and text. Our results, benchmarked against contemporary models, manifest a marked improvement in caption generation for both single-image and multi-image memes, as well as different meme categories. \textsc{XMeCap} achieves an average evaluation score of 75.85 for single-image memes and 66.32 for multi-image memes, outperforming the best baseline by 6.75\% and 8.56\%, respectively. This research not only establishes a new frontier in meme-related studies but also underscores the potential of machines in understanding and generating humor in a multi-modal setting.

cs.CV↗

Polarization-Independent Zero Directional Scattering Without Geometric Symmetries

As the characteristic feature of generalized Kerker effect in Mie theory, directional scattering elimination has been playing a pivotal role in nanophotonics and many other photonic disciplines, such as singular optics and topological photonics. Generally, zero directional scattering can be obtained only for a specific incident polarization, and to make it fully independent of arbitrary polarizations would require scatterers that exhibit geometric (\textit{e.g.} mirror) symmetries. Here we revisit the generalized Kerker effect and directional scattering elimination from the perspective of not the conventional electromagnetic multipoles, but rather quasi-normal modes supported by non-Hermitian systems. We reveal how to obtain zero directional scattering that is independent of arbitrary incident polarizations, even for scattering structures that do not exhibit the required geometric symmetries. Such geometric symmetry-free and polarization-independent responses are made accessible through a synchronous exploitation of electromagnetic reciprocity and geometric phase. Our discovery can stimulate fundamental explorations and practical applications in not only photonics, but also many other wave physics branches where scattering and geometric phase are pervasive.

physics.optics↗

COMAE: COMprehensive Attribute Exploration for Zero-shot Hashing

Zero-shot hashing (ZSH) has shown excellent success owing to its efficiency and generalization in large-scale retrieval scenarios. While considerable success has been achieved, there still exist urgent limitations. Existing works ignore the locality relationships of representations and attributes, which have effective transferability between seeable classes and unseeable classes. Also, the continuous-value attributes are not fully harnessed. In response, we conduct a COMprehensive Attribute Exploration for ZSH, named COMAE, which depicts the relationships from seen classes to unseen ones through three meticulously designed explorations, i.e., point-wise, pair-wise and class-wise consistency constraints. By regressing attributes from the proposed attribute prototype network, COMAE learns the local features that are relevant to the visual attributes. Then COMAE utilizes contrastive learning to comprehensively depict the context of attributes, rather than instance-independent optimization. Finally, the class-wise constraint is designed to cohesively learn the hash code, image representation, and visual attributes more effectively. Experimental results on the popular ZSH datasets demonstrate that COMAE outperforms state-of-the-art hashing techniques, especially in scenarios with a larger number of unseen label classes.

cs.CV↗

CellVerse: Do Large Language Models Really Understand Cell Biology?

Recent studies have demonstrated the feasibility of modeling single-cell data as natural languages and the potential of leveraging powerful large language models (LLMs) for understanding cell biology. However, a comprehensive evaluation of LLMs' performance on language-driven single-cell analysis tasks still remains unexplored. Motivated by this challenge, we introduce CellVerse, a unified language-centric question-answering benchmark that integrates four types of single-cell multi-omics data and encompasses three hierarchical levels of single-cell analysis tasks: cell type annotation (cell-level), drug response prediction (drug-level), and perturbation analysis (gene-level). Going beyond this, we systematically evaluate the performance across 14 open-source and closed-source LLMs ranging from 160M to 671B on CellVerse. Remarkably, the experimental results reveal: (1) Existing specialist models (C2S-Pythia) fail to make reasonable decisions across all sub-tasks within CellVerse, while generalist models such as Qwen, Llama, GPT, and DeepSeek family models exhibit preliminary understanding capabilities within the realm of cell biology. (2) The performance of current LLMs falls short of expectations and has substantial room for improvement. Notably, in the widely studied drug response prediction task, none of the evaluated LLMs demonstrate significant performance improvement over random guessing. CellVerse offers the first large-scale empirical demonstration that significant challenges still remain in applying LLMs to cell biology. By introducing CellVerse, we lay the foundation for advancing cell biology through natural languages and hope this paradigm could facilitate next-generation single-cell analysis.

q-bio.QM↗

Audio-text Retrieval with Transformer-based Hierarchical Alignment and Disentangled Cross-modal Representation

Most existing audio-text retrieval (ATR) approaches typically rely on a single-level interaction to associate audio and text, limiting their ability to align different modalities and leading to suboptimal matches. In this work, we present a novel ATR framework that leverages two-stream Transformers in conjunction with a Hierarchical Alignment (THA) module to identify multi-level correspondences of different Transformer blocks between audio and text. Moreover, current ATR methods mainly focus on learning a global-level representation, missing out on intricate details to capture audio occurrences that correspond to textual semantics. To bridge this gap, we introduce a Disentangled Cross-modal Representation (DCR) approach that disentangles high-dimensional features into compact latent factors to grasp fine-grained audio-text semantic correlations. Additionally, we develop a confidence-aware (CA) module to estimate the confidence of each latent factor pair and adaptively aggregate cross-modal latent factors to achieve local semantic alignment. Experiments show that our THA effectively boosts ATR performance, with the DCR approach further contributing to consistent performance gains.

cs.SD↗