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Zhijian Yang

Publications and source records attributed to Zhijian Yang.

At least 19 recordsLinked to original sources

Polarization-Conditioned Fourier-enhanced DeepONet for Electric Field Reconstruction from EFISH Measurements

Electric-field-induced second-harmonic generation (EFISH) is an established laser diagnostic for quantifying electric fields in plasmas, yet ensuring field accuracy remains challenging given the coherent, path-integrated nature of the signal. We address this via machine learning, developing a Polarization-Conditioned Fourier-enhanced Deep Operator Network (PC-FDON) -- a unified operator-learning model that reconstructs field profiles from EFISH measurements across both polarizations and various optical parameters. Its architecture incorporates three advances: (i) a Fourier-enhanced branch providing inductive bias for the Gouy phase shift and wave-vector mismatch; (ii) a polarization-conditioning branch encoding signal polarization via Feature-wise Linear Modulation (FiLM) and gated units, enabling one model to handle both polarizations; and (iii) a physics-informed loss enforcing self-consistency with the governing EFISH equation. Trained on data spanning multiple function families, polarization states, and phase-mismatch values, PC-FDON achieves promising reconstruction under noise-free, incomplete, and noisy inputs, with generalizability comparable to our previous polarization-specific model. Pointwise epistemic uncertainty estimates via Monte Carlo dropout reflect model confidence and enable out-of-distribution (OOD) detection through a location-dependent exceedance fraction metric. Validation is performed on realistic electrode configurations under both polarizations and varying Rayleigh ranges, including a simulated surface dielectric barrier discharge where the framework correctly flags OOD inputs, and experimental data showing good agreement with simulations. The architecture -- spectral inductive bias, conditional modulation, and dataset-specific uncertainty -- shows strong potential for broader application beyond plasma diagnostics.

physics.plasm-ph

WavesFM: Hierarchical Representation Learning for Longitudinal Wearable Sensor Waveforms

Wearable sensors enable the continuous acquisition of high-resolution physiological waveforms, such as photoplethysmography and accelerometry, under free-living conditions. However, inferring health-related phenotypes from these signals presents significant challenges due to high sampling frequencies, multimodal dependencies, and extreme sequence lengths (e.g., weeks of recordings), compounded by a scarcity of ground-truth labels. To address these challenges, existing self-supervised learning (SSL) methodologies typically follow two paradigms: (1) learning rich morphological representations from short waveform segments while collapsing longitudinal dynamics through simple aggregation, or (2) modeling behavioral patterns from coarse, hand-crafted features (e.g. heart rate, step counts) spanning longer horizons but foregoing subtle, predictive signatures in raw waveforms. To bridge this gap, we propose WavesFM, a foundation model utilizing a two-stage SSL framework for longitudinal physiological data. Specifically, we decompose the learning problem into two stages: first, a segment-level encoder is pretrained to extract local embeddings from short waveforms; subsequently, a temporal encoder is trained to model the sequence of these embeddings across a multi-day horizon. This hierarchical approach overcomes the computational complexity of high-resolution, long-sequence data, allowing the overall model to capture both local signal semantics and the complex circadian and inter-day variations governing physiological dynamics. Pretrained on over 6.8M hours (N=324k individuals) of recordings for the first stage and 5.3M hours (N=10k) for the second stage, WavesFM demonstrates superior performance across 58 diverse tasks spanning demographics, lifestyle, health conditions, and medications.

cs.LG

An Interpretable Operator-Learning Model for Electric Field Profile Reconstruction in Discharges Based on the EFISH Method

Machine learning (ML) models have recently been used to reconstruct electric field distributions from EFISH signal profiles-the 'inverse EFISH problem'. This addresses the line-of-sight EFISH inaccuracy caused by the Gouy phase shift in focused beams. A key benefit of this approach is that the accuracy of the reconstructed profile can be directly checked via a 'forward transform' of the EFISH equation. Motivated by this latest success, the present study introduces a novel ML model with markedly improved performance. Based on a more powerful operator-learning architecture, it goes beyond the ANNs and CNNs employed previously. Termed Decoder-DeepONet (DDON), its main strength is learning function-to-function mappings, essential for recovering electric field profiles of unknown shape. The superior performance of DDON is exemplified via a comparison with our published CNN model and the feasibility of a classical mathematical method, as well as its application to both discharge simulations and experimental EFISH data from a nanosecond pulsed discharge. In almost all cases, the DDON model exhibits better generalizability, higher prediction accuracy, and wider applicability. Furthermore, the intrinsic nature of this operator-learning architecture renders it less sensitive to the exact location(s) of the acquired data, enabling electric field reconstruction even with seemingly 'incomplete' input profiles--an issue often accompanying poor signal sensitivity. We also employ Integrated Gradients (IG) to identify the signal regions most critical to reconstruction accuracy, providing guidance on the optimal sampling window for EFISH acquisition. Overall, we believe that the DDON model is a robust and comprehensive model which can be readily applied to reconstruct 'bell-shaped' electric field profiles with an existing axis of symmetry, especially in non-equilibrium plasmas.

physics.plasm-ph

Can NeRFs See without Cameras?

Neural Radiance Fields (NeRFs) have been remarkably successful at synthesizing novel views of 3D scenes by optimizing a volumetric scene function. This scene function models how optical rays bring color information from a 3D object to the camera pixels. Radio frequency (RF) or audio signals can also be viewed as a vehicle for delivering information about the environment to a sensor. However, unlike camera pixels, an RF/audio sensor receives a mixture of signals that contain many environmental reflections (also called "multipath"). Is it still possible to infer the environment using such multipath signals? We show that with redesign, NeRFs can be taught to learn from multipath signals, and thereby "see" the environment. As a grounding application, we aim to infer the indoor floorplan of a home from sparse WiFi measurements made at multiple locations inside the home. Although a difficult inverse problem, our implicitly learnt floorplans look promising, and enables forward applications, such as indoor signal prediction and basic ray tracing.

cs.CV

Decipher-MR: A Vision-Language Foundation Model for 3D MRI Representations

Magnetic Resonance Imaging is a critical imaging modality in clinical diagnosis and research, yet its complexity and heterogeneity hinder scalable, generalizable machine learning. Although foundation models have revolutionized language and vision tasks, their application to MRI remains constrained by data scarcity and narrow anatomical focus. We present Decipher-MR, a 3D MRI-specific vision-language foundation model trained on 200,000 MRI series from over 22,000 studies spanning diverse anatomical regions, sequences, and pathologies. Decipher-MR integrates self-supervised vision learning with report-guided text supervision to build robust representations for broad applications. To enable efficient use, Decipher-MR supports a modular design that enables tuning of lightweight, task-specific decoders attached to a frozen pretrained encoder. Following this setting, we evaluate Decipher-MR across disease classification, demographic prediction, anatomical localization, and cross-modal retrieval, demonstrating consistent improvements over existing foundation models and task-specific approaches. These results position Decipher-MR as a versatile foundation for MRI-based AI in clinical and research settings.

cs.CV

Dynamics for a viscoelastic beam equation with past history and nonlocal boundary dissipation

This article aims to study the long-time dynamics of the linear viscoelastic plate equation $\displaystyle{u_{tt}+Δ^2 u-\int_τ^tg(t-s)Δ^2u(s)ds=0}$ subject to nonlinear and nonlocal boundary conditions. This model, with $τ=0$, was first considered by Cavalcanti (Discrete Contin. Dyn. Syst., 8(3), 675-695, 2002), where results of global existence and uniform decay rates of energy have been established. In this work, by taking $τ=-\infty$, and considering the autonomous equivalent problem we prove that the dynamical system $(\mathcal{H},S_t)$ generated by the weak solutions has a compact global attractor $\mathfrak{A}$ (in the topology of the weak phase space $\mathcal{H}$), which in subcritical case has finite dimension and smoothness. Furthermore, when the force follows the {\it Hook Law}, we prove that $(\mathcal{H},S_t)$ possesses a (generalized) fractal exponential attractor $\mathfrak{A}_{\exp}$ with finite dimension in a space $\widetilde{\mathcal{H}}\supset\mathcal{H}$.

math.AP

Novel constants based on the generalization of Von Neumann-Jordan constant

We introduce a new geometric constant based on a generalization of the parallelogram law, and study its properties as well as some relationships with other well-known geometric constants. A sufficient condition for normal structure is presented. Next, we introduce a constant and calculate its value in a specific space. Furthermore, we introduce another new constant and investigate some of its basic properties.

math.FA

Enhancing SAM with Efficient Prompting and Preference Optimization for Semi-supervised Medical Image Segmentation

Foundational models such as the Segment Anything Model (SAM) are gaining traction in medical imaging segmentation, supporting multiple downstream tasks. However, such models are supervised in nature, still relying on large annotated datasets or prompts supplied by experts. Conventional techniques such as active learning to alleviate such limitations are limited in scope and still necessitate continuous human involvement and complex domain knowledge for label refinement or establishing reward ground truth. To address these challenges, we propose an enhanced Segment Anything Model (SAM) framework that utilizes annotation-efficient prompts generated in a fully unsupervised fashion, while still capturing essential semantic, location, and shape information through contrastive language-image pretraining and visual question answering. We adopt the direct preference optimization technique to design an optimal policy that enables the model to generate high-fidelity segmentations with simple ratings or rankings provided by a virtual annotator simulating the human annotation process. State-of-the-art performance of our framework in tasks such as lung segmentation, breast tumor segmentation, and organ segmentation across various modalities, including X-ray, ultrasound, and abdominal CT, justifies its effectiveness in low-annotation data scenarios.

cs.CV

Generative models of MRI-derived neuroimaging features and associated dataset of 18,000 samples

Availability of large and diverse medical datasets is often challenged by privacy and data sharing restrictions. For successful application of machine learning techniques for disease diagnosis, prognosis, and precision medicine, large amounts of data are necessary for model building and optimization. To help overcome such limitations in the context of brain MRI, we present GenMIND: a collection of generative models of normative regional volumetric features derived from structural brain imaging. GenMIND models are trained on real brain imaging regional volumetric measures from the iSTAGING consortium, which encompasses over 40,000 MRI scans across 13 studies, incorporating covariates such as age, sex, and race. Leveraging GenMIND, we produce and offer 18,000 synthetic samples spanning the adult lifespan (ages 22-90 years), alongside the model's capability to generate unlimited data. Experimental results indicate that samples generated from GenMIND agree with the distributions obtained from real data. Most importantly, the generated normative data significantly enhance the accuracy of downstream machine learning models on tasks such as disease classification. Data and models are available at: https://huggingface.co/spaces/rongguangw/GenMIND.

q-bio.QM

Dimensional Neuroimaging Endophenotypes: Neurobiological Representations of Disease Heterogeneity Through Machine Learning

Machine learning has been increasingly used to obtain individualized neuroimaging signatures for disease diagnosis, prognosis, and response to treatment in neuropsychiatric and neurodegenerative disorders. Therefore, it has contributed to a better understanding of disease heterogeneity by identifying disease subtypes that present significant differences in various brain phenotypic measures. In this review, we first present a systematic literature overview of studies using machine learning and multimodal MRI to unravel disease heterogeneity in various neuropsychiatric and neurodegenerative disorders, including Alzheimer disease, schizophrenia, major depressive disorder, autism spectrum disorder, multiple sclerosis, as well as their potential in transdiagnostic settings. Subsequently, we summarize relevant machine learning methodologies and discuss an emerging paradigm which we call dimensional neuroimaging endophenotype (DNE). DNE dissects the neurobiological heterogeneity of neuropsychiatric and neurodegenerative disorders into a low dimensional yet informative, quantitative brain phenotypic representation, serving as a robust intermediate phenotype (i.e., endophenotype) largely reflecting underlying genetics and etiology. Finally, we discuss the potential clinical implications of the current findings and envision future research avenues.

cs.LG

Sampling via Föllmer Flow

We introduce a novel unit-time ordinary differential equation (ODE) flow called the preconditioned Föllmer flow, which efficiently transforms a Gaussian measure into a desired target measure at time 1. To discretize the flow, we apply Euler's method, where the velocity field is calculated either analytically or through Monte Carlo approximation using Gaussian samples. Under reasonable conditions, we derive a non-asymptotic error bound in the Wasserstein distance between the sampling distribution and the target distribution. Through numerical experiments on mixture distributions in 1D, 2D, and high-dimensional spaces, we demonstrate that the samples generated by our proposed flow exhibit higher quality compared to those obtained by several existing methods. Furthermore, we propose leveraging the Föllmer flow as a warmstart strategy for existing Markov Chain Monte Carlo (MCMC) methods, aiming to mitigate mode collapses and enhance their performance. Finally, thanks to the deterministic nature of the Föllmer flow, we can leverage deep neural networks to fit the trajectory of sample evaluations. This allows us to obtain a generator for one-step sampling as a result.

stat.ME

A Continuum Model for Dislocation Climb

Dislocation climb plays an important role in understanding plastic deformation of metallic materials at high temperature. In this paper, we present a continuum formulation for dislocation climb velocity based on densities of dislocations. The obtained continuum formulation is an accurate approximation of the Green's function based discrete dislocation dynamics method (Gu et al. J. Mech. Phys. Solids 83:319-337, 2015). The continuum dislocation climb formulation has the advantage of accounting for both the long-range effect of vacancy bulk diffusion and that of the Peach-Koehler climb force, and the two longrange effects are canceled into a short-range effect (integral with fast-decaying kernel) and in some special cases, a completely local effect. This significantly simplifies the calculation in the Green's function based discrete dislocation dynamics method, in which a linear system has to be solved over the entire system for the long-range effect of vacancy diffusion and the long-range Peach-Koehler climb force has to be calculated. This obtained continuum dislocation climb velocity can be applied in any available continuum dislocation dynamics frameworks. We also present numerical validations for this continuum climb velocity and simulation examples for implementation in continuum dislocation dynamics frameworks.

cond-mat.mtrl-sci

Applications of Generative Adversarial Networks in Neuroimaging and Clinical Neuroscience

Generative adversarial networks (GANs) are one powerful type of deep learning models that have been successfully utilized in numerous fields. They belong to a broader family called generative methods, which generate new data with a probabilistic model by learning sample distribution from real examples. In the clinical context, GANs have shown enhanced capabilities in capturing spatially complex, nonlinear, and potentially subtle disease effects compared to traditional generative methods. This review appraises the existing literature on the applications of GANs in imaging studies of various neurological conditions, including Alzheimer's disease, brain tumors, brain aging, and multiple sclerosis. We provide an intuitive explanation of various GAN methods for each application and further discuss the main challenges, open questions, and promising future directions of leveraging GANs in neuroimaging. We aim to bridge the gap between advanced deep learning methods and neurology research by highlighting how GANs can be leveraged to support clinical decision making and contribute to a better understanding of the structural and functional patterns of brain diseases.

cs.LG

Gene-SGAN: a method for discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering

Disease heterogeneity has been a critical challenge for precision diagnosis and treatment, especially in neurologic and neuropsychiatric diseases. Many diseases can display multiple distinct brain phenotypes across individuals, potentially reflecting disease subtypes that can be captured using MRI and machine learning methods. However, biological interpretability and treatment relevance are limited if the derived subtypes are not associated with genetic drivers or susceptibility factors. Herein, we describe Gene-SGAN - a multi-view, weakly-supervised deep clustering method - which dissects disease heterogeneity by jointly considering phenotypic and genetic data, thereby conferring genetic correlations to the disease subtypes and associated endophenotypic signatures. We first validate the generalizability, interpretability, and robustness of Gene-SGAN in semi-synthetic experiments. We then demonstrate its application to real multi-site datasets from 28,858 individuals, deriving subtypes of Alzheimer's disease and brain endophenotypes associated with hypertension, from MRI and SNP data. Derived brain phenotypes displayed significant differences in neuroanatomical patterns, genetic determinants, biological and clinical biomarkers, indicating potentially distinct underlying neuropathologic processes, genetic drivers, and susceptibility factors. Overall, Gene-SGAN is broadly applicable to disease subtyping and endophenotype discovery, and is herein tested on disease-related, genetically-driven neuroimaging phenotypes.

q-bio.QM

New Geometric Constant Related to the P-angle Function in Banach Spaces

In this paper, combined with the P-angle function of Banach spaces and the geometric constants that can characterize Hilbert spaces, the new angular geometric constant is defined. Firstly, this paper explores the basic properties of the new constant and obtains some inequalities with significant geometric constants. Then according to the derived inequalities, this paper studies the relationship between the new constant and the geometric properties of Banach spaces. Furthermore, the necessary and sufficient condition for uniform non-squareness, and the sufficient conditions for uniform convexity, the normal structure and the fixed point property will be established.

math.FA

Surreal-GAN:Semi-Supervised Representation Learning via GAN for uncovering heterogeneous disease-related imaging patterns

A plethora of machine learning methods have been applied to imaging data, enabling the construction of clinically relevant imaging signatures of neurological and neuropsychiatric diseases. Oftentimes, such methods don't explicitly model the heterogeneity of disease effects, or approach it via nonlinear models that are not interpretable. Moreover, unsupervised methods may parse heterogeneity that is driven by nuisance confounding factors that affect brain structure or function, rather than heterogeneity relevant to a pathology of interest. On the other hand, semi-supervised clustering methods seek to derive a dichotomous subtype membership, ignoring the truth that disease heterogeneity spatially and temporally extends along a continuum. To address the aforementioned limitations, herein, we propose a novel method, termed Surreal-GAN (Semi-SUpeRvised ReprEsentAtion Learning via GAN). Using cross-sectional imaging data, Surreal-GAN dissects underlying disease-related heterogeneity under the principle of semi-supervised clustering (cluster mappings from normal control to patient), proposes a continuously dimensional representation, and infers the disease severity of patients at individual level along each dimension. The model first learns a transformation function from normal control (CN) domain to the patient (PT) domain with latent variables controlling transformation directions. An inverse mapping function together with regularization on function continuity, pattern orthogonality and monotonicity was also imposed to make sure that the transformation function captures necessarily meaningful imaging patterns with clinical significance. We first validated the model through extensive semi-synthetic experiments, and then demonstrate its potential in capturing biologically plausible imaging patterns in Alzheimer's disease (AD).

cs.LG

New geometric constants of isosceles orthogonal type

Based on the parallelogram law and isosceles orthogonality, we define a new orthogonal geometric constant. We first discuss some basic properties of this new constant. Next, we consider the relation between the constant and the uniformly non-square property. Moreover, a generalized constant is also introduced and some basic properties are presented. It is shown that, for a normed space, the constant value is equal to 1 if and only if the norm can be induced by the inner product. Finally, we verify that this constant is closely related to the well-known geometric constants through some inequalities.

math.FA

Subtyping brain diseases from imaging data

The imaging community has increasingly adopted machine learning (ML) methods to provide individualized imaging signatures related to disease diagnosis, prognosis, and response to treatment. Clinical neuroscience and cancer imaging have been two areas in which ML has offered particular promise. However, many neurologic and neuropsychiatric diseases, as well as cancer, are often heterogeneous in terms of their clinical manifestations, neuroanatomical patterns or genetic underpinnings. Therefore, in such cases, seeking a single disease signature might be ineffectual in delivering individualized precision diagnostics. The current chapter focuses on ML methods, especially semi-supervised clustering, that seek disease subtypes using imaging data. Work from Alzheimer Disease and its prodromal stages, psychosis, depression, autism, and brain cancer are discussed. Our goal is to provide the readers with a broad overview in terms of methodology and clinical applications.

cs.LG