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Zhijie Bao

Publications and source records attributed to Zhijie Bao.

5 recordsLinked to original sources

ObGynLongBench: Revealing the Evidence-to-EHR Gap in Longitudinal EHR Decision-Making

The application of large language models (LLMs) to personalized medical assistants has garnered growing interest. However, existing medical benchmarks largely rely on static question answering with pre-selected evidence, leaving unclear whether LLMs can make reliable clinical decisions from real longitudinal electronic health records (EHRs). To bridge this gap, we introduce ObGynLongBench, a rule-grounded long-context EHR benchmark for obstetric and gynecologic decision-making, comprising 1,500 clinical decision-point cases from 976 real pregnancy EHR histories and traceable rules. Each case is anchored to a patient, a pregnancy-timeline point, and a pre-decision information boundary, enabling Evidence-only, Visit-level EHR, and History-level EHR evaluation. Evaluating 17 LLMs reveals a substantial Evidence-to-EHR Gap: models perform well when evidence is directly provided, but accuracy drops when evidence must be extracted from same-day records or full pre-decision EHR histories. Further analyses identify evidence utilization as a key bottleneck: performance decreases with longer EHR contexts and more complex evidence requirements, and earlier failures often predict later failures within the same patient history. Finally, active-search agents perform best among EHR access strategies, highlighting patient-specific evidence utilization as a central challenge for reliable personalized medical assistants. Resources are available at https://github.com/xiangjun2003/ObgynLongbench.

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MedRCube: A Multidimensional Framework for Fine-Grained and In-Depth Evaluation of MLLMs in Medical Imaging

The potential of Multimodal Large Language Models (MLLMs) in domain of medical imaging raise the demands of systematic and rigorous evaluation frameworks that are aligned with the real-world medical imaging practice. Existing practices that report single or coarse-grained metrics are lack the granularity required for specialized clinical support and fail to assess the reliability of reasoning mechanisms. To address this, we propose a paradigm shift toward multidimensional, fine-grained and in-depth evaluation. Based on a two-stage systematic construction pipeline designed for this paradigm, we instantiate it with MedRCube. We benchmark 33 MLLMs, \textit{Lingshu-32B} achieve top-tier performance. Crucially, MedRCube exposes a series of pronounced insights inaccessible under prior evaluation settings. Furthermore, we introduce a credibility evaluation subset to quantify reasoning credibility, uncover a highly significant positive association between shortcut behavior and diagnostic task performance, raising concerns for clinically trustworthy deployment. The resources of this work can be found at https://github.com/F1mc/MedRCube.

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Strong Reasoning Isn't Enough: Evaluating Evidence Elicitation in Interactive Diagnosis

Interactive medical consultation requires an agent to proactively elicit missing clinical evidence under uncertainty. Yet existing evaluations largely remain static or outcome-centric, neglecting the evidence-gathering process. In this work, we propose an interactive evaluation framework that explicitly models the consultation process using a simulated patient and a \rev{simulated reporter} grounded in atomic evidences. Based on this representation, we introduce Information Coverage Rate (ICR) to quantify how completely an agent uncovers necessary evidence during interaction. To support systematic study, we build EviMed, an evidence-based benchmark spanning diverse conditions from common complaints to rare diseases, and evaluate 10 models with varying reasoning abilities. We find that strong diagnostic reasoning does not guarantee effective information collection, and this insufficiency acts as a primary bottleneck limiting performance in interactive settings. To address this, we propose REFINE, a strategy that leverages diagnostic verification to guide the agent in proactively resolving uncertainties. Extensive experiments demonstrate that REFINE consistently outperforms baselines across diverse datasets and facilitates effective model collaboration, enabling smaller agents to achieve superior performance under strong reasoning supervision. Our code can be found at https://github.com/NanshineLoong/EID-Benchmark .

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PIORS: Personalized Intelligent Outpatient Reception based on Large Language Model with Multi-Agents Medical Scenario Simulation

In China, receptionist nurses face overwhelming workloads in outpatient settings, limiting their time and attention for each patient and ultimately reducing service quality. In this paper, we present the Personalized Intelligent Outpatient Reception System (PIORS). This system integrates an LLM-based reception nurse and a collaboration between LLM and hospital information system (HIS) into real outpatient reception setting, aiming to deliver personalized, high-quality, and efficient reception services. Additionally, to enhance the performance of LLMs in real-world healthcare scenarios, we propose a medical conversational data generation framework named Service Flow aware Medical Scenario Simulation (SFMSS), aiming to adapt the LLM to the real-world environments and PIORS settings. We evaluate the effectiveness of PIORS and SFMSS through automatic and human assessments involving 15 users and 15 clinical experts. The results demonstrate that PIORS-Nurse outperforms all baselines, including the current state-of-the-art model GPT-4o, and aligns with human preferences and clinical needs. Further details and demo can be found at https://github.com/FudanDISC/PIORS

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DISC-MedLLM: Bridging General Large Language Models and Real-World Medical Consultation

We propose DISC-MedLLM, a comprehensive solution that leverages Large Language Models (LLMs) to provide accurate and truthful medical response in end-to-end conversational healthcare services. To construct high-quality Supervised Fine-Tuning (SFT) datasets, we employ three strategies: utilizing medical knowledge-graphs, reconstructing real-world dialogues, and incorporating human-guided preference rephrasing. These datasets are instrumental in training DISC-MedLLM, surpassing existing medical LLMs in both single-turn and multi-turn consultation scenarios. Extensive experimental results demonstrate the effectiveness of the proposed model in bridging the gap between general language models and real-world medical consultation. Additionally, we release the constructed dataset and model weights to further contribute to research and development. Further details and resources can be found at https://github.com/FudanDISC/DISC-MedLLM

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