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Zhiqiang Shao

Publications and source records attributed to Zhiqiang Shao.

8 recordsLinked to original sources

A Disease-Centric Vision-Language Foundation Model for Precision Oncology in Kidney Cancer

The non-invasive assessment of increasingly incidentally discovered renal masses is a critical challenge in urologic oncology, where diagnostic uncertainty frequently leads to the overtreatment of benign or indolent tumors. In this study, we developed and validated RenalCLIP using a dataset of 27,866 CT scans from 8,809 patients across nine Chinese medical centers and the public TCIA cohort, a visual-language foundation model for characterization, diagnosis and prognosis of renal mass. The model was developed via a two-stage pre-training strategy that first enhances the image and text encoders with domain-specific knowledge before aligning them through a contrastive learning objective, to create robust representations for superior generalization and diagnostic precision. RenalCLIP achieved better performance and superior generalizability across 10 core tasks spanning the full clinical workflow of kidney cancer, including anatomical assessment, diagnostic classification, and survival prediction, compared with other state-of-the-art general-purpose CT foundation models. Especially, for complicated task like recurrence-free survival prediction in the TCIA cohort, RenalCLIP achieved a C-index of 0.726, representing a substantial improvement of approximately 20% over the leading baselines. Furthermore, RenalCLIP's pre-training imparted remarkable data efficiency; in the diagnostic classification task, it only needs 20% training data to achieve the peak performance of all baseline models even after they were fully fine-tuned on 100% of the data. Additionally, it achieved superior performance in report generation, image-text retrieval and zero-shot diagnosis tasks. Our findings establish that RenalCLIP provides a robust tool with the potential to enhance diagnostic accuracy, refine prognostic stratification, and personalize the management of patients with kidney cancer.

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Measure solutions to piston problem for compressible fluid flow of generalized chaplygin gas

We study the piston problem of the compressible fluid flow with the generalized Chaplygin gas. Depending on the inferential critical value of Mach number, we prove that, there exists an integral weak solution for the proceeding piston problem, consisting of a shock separating constant states ahead of the piston if Mach numbers less than this critical value, while a singular measure solution, with density containing a Dirac measure supported on the piston, shall be proposed to solve the proceeding piston problem if Mach numbers greater than or equal to the critical value. For the receding piston problem, rarefaction wave solution always exists when the piston recedes from the gas with any constant speed. Moreover, the occurrence of vacuum state and the convergence of solutions, as well as degeneration of equations are analyzed in the receding case as Mach number tends to infinity.

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Piston problem to the isentropic Euler equations for modified Chaplygin gas

In this paper, we solve constructively the piston problem for one-dimensional isentropic Euler equations of modified Chaplygin gas. In solutions, we prove rigorously the global existence and uniqueness of a shock wave separating constant states ahead of the piston when the piston pushed forward into the gas. It is quite different from the results of Chaplygin gas or generalized Chaplygin gas in which a Radon measure solution is constructed to deal with concentration of mass on the piston. When the piston pulled back from the gas, we strictly confirm only the first family rarefaction wave exists in front of the piston and the concentration will never occur. In addition, by studying the limiting behavior, we show that the piston solutions of modified Chaplygin gas equations tend to the piston solutions of generalized or pure Chaplygin gas equations as a single parameter of pressure state function vanishes.

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The pressureless limits of Riemann solutions to the Euler equations of one-dimensional compressible fluid flow with a source term

In this paper, we study the limits of Riemann solutions to the inhomogeneous Euler equations of one-dimensional compressible fluid flow as the adiabatic exponent $γ$ tends to one. Different from the homogeneous equations, the Riemann solutions of the inhomogeneous system are non self-similar. It is rigorously shown that, as $γ$ tends to one, any two-shock Riemann solution tends to a delta shock solution of the pressureless Euler system with a source term, and the intermediate density between the two shocks tends to a weighted $δ$-mesaure which forms the delta shock; while any two-rarefaction-wave Riemann solution tends to a two-contact-discontinuity solution of the pressureless Euler system with a source term, whose intermediate state between the two contact discontinuities is a vacuum state. Moreover, we also give some numerical results to confirm the theoretical analysis.

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Concentration of mass in the pressureless limit of the Euler equations of one-dimensional compressible fluid flow

In this paper, we study the limiting behavior of Riemann solutions to the Euler equations of one-dimensional compressible fluid flow as $γ$ tends to one. We show that the limit solution forms the delta wave to the pressureless Euler system of one-dimensional compressible fluid flow in the distribution sense. Some numerical results exhibiting the phenomena of concentration are also presented.

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Concentration in vanishing adiabatic exponent limit of solutions to the Aw-Rascle traffic model

In this paper, we study the phenomenon of concentration and the formation of delta shock wave in vanishing adiabatic exponent limit of Riemann solutions to the Aw-Rascle traffic model. It is proved that as the adiabatic exponent vanishes, the limit of solutions tends to a special delta-shock rather than the classical one to the zero pressure gas dynamics. In order to further study this problem, we consider a perturbed Aw-Rascle model and proceed to investigate the limits of solutions. We rigorously proved that, as $γ$ tends to one, any Riemann solution containing two shock waves tends to a delta-shock to the zero pressure gas dynamics in the distribution sense. Moreover, some representative numerical simulations are exhibited to confirm the theoretical analysis.

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Delta shocks in the relativistic full Euler equations for a Chaplygin gas

The relativistic full Euler equations for a Chaplygin gas are studied. The Riemann problem is solved constructively. There are two kinds of Riemann solutions, in which one consists of three contact discontinuities and the other involves a delta shock wave on which both state variables the rest mass density and the proper energy density simultaneously contain the Dirac delta functions. It is quite different from the previous ones on which only one state variable contains the Dirac delta function. The formation mechanism, generalized Rankine-Hugoniot relation and entropy condition are clarified for this type of delta shock wave. Under the generalized Rankine-Hugoniot relation and entropy condition, the existence and uniqueness of delta shock solutions are also established.

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Delta shocks and vacuum states for the isentropic magnetogasdynamics equations for Chaplygin gas as pressure and magnetic field vanish

This paper is concerned with the Riemann problem for the isentropic Chaplygin gas magnetogasdynamics equations and the formation of delta shocks and vacuum states as pressure and magnetic field vanish. Firstly, the Riemann problem of the isentropic magnetogasdynamics equations for Chaplygin gas is solved analytically. Secondly, it is rigorously proved that, as both the pressure and the magnetic field vanish, the Riemann solution containing two shock waves tends to a delta shock solution to the transport equations, and the intermediate density between the two shocks tends to a weighted $δ$-measure which forms the delta shock; while the Riemann solution containing two rarefaction waves tends to a two-contact-discontinuity solution to the transport equations, the termediate state between the two contact discontinuities is a vacuum state.

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