Zhirong Xu | Searcharxiv

arXiv2026

Clinician-Friendly Foundation Models for Ophthalmic Image Diagnostics without Fine-Tuning or Technical Barriers

Artificial intelligence (AI) shows remarkable potential in medical imaging diagnostics, yet most current models require retraining when applied across different clinical settings, limiting their scalability. We developed GlobeReady, a deployment-oriented platform powered by the RetiGlobe foun- dation model and local feature augmentation. RetiGlobe was pretrained in two stages: 1) self-supervised learning using DINOv2 on 38 million synthetic ophthalmic images, and 2) contrastive learning using CLIP on 475,845 real image-text pairs spanning diverse ethnicities, imaging devices, and geographic regions worldwide. We evaluate GlobeReady on 488,448 ophthalmic images, including color fundus photographs (CFPs) and optical coherence tomography scans, from multi-centres in China, Singapore, Vietnam and the UK. Prospective testing included usability assessment with 31 ophthalmologists. Exploratory analyses evaluated domain generalisability, Bayesian uncertainty quantification, out-of-distribution (OOD) detection, and feature-based case retrieval.

cs.CV↗

arXiv2022

AMCAD: Adaptive Mixed-Curvature Representation based Advertisement Retrieval System

Graph embedding based retrieval has become one of the most popular techniques in the information retrieval community and search engine industry. The classical paradigm mainly relies on the flat Euclidean geometry. In recent years, hyperbolic (negative curvature) and spherical (positive curvature) representation methods have shown their superiority to capture hierarchical and cyclic data structures respectively. However, in industrial scenarios such as e-commerce sponsored search platforms, the large-scale heterogeneous query-item-advertisement interaction graphs often have multiple structures coexisting. Existing methods either only consider a single geometry space, or combine several spaces manually, which are incapable and inflexible to model the complexity and heterogeneity in the real scenario. To tackle this challenge, we present a web-scale Adaptive Mixed-Curvature ADvertisement retrieval system (AMCAD) to automatically capture the complex and heterogeneous graph structures in non-Euclidean spaces. Specifically, entities are represented in adaptive mixed-curvature spaces, where the types and curvatures of the subspaces are trained to be optimal combinations. Besides, an attentive edge-wise space projector is designed to model the similarities between heterogeneous nodes according to local graph structures and the relation types. Moreover, to deploy AMCAD in Taobao, one of the largest ecommerce platforms with hundreds of million users, we design an efficient two-layer online retrieval framework for the task of graph based advertisement retrieval. Extensive evaluations on real-world datasets and A/B tests on online traffic are conducted to illustrate the effectiveness of the proposed system.

cs.IR↗