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Zhixuan Ge

Publications and source records attributed to Zhixuan Ge.

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OrganLens: Organ-Specific Representation Learning for CT Foundation Models

A CT examination captures multiple organs, but many biomedical questions concern abnormalities, prognosis, or longitudinal change in a specific organ. These questions require a separate representation for each organ within the same CT volume. Existing CT foundation models commonly produce a single volume-level representation, while recent anatomy-aware methods either encode pre-separated organ volumes or explicitly disentangle images into organ token groups. The former may remove clinically relevant surrounding context, while the latter does not condition a shared encoder on a selected organ before its features are formed. We introduce OrganLens for organ-specific representation learning through self-supervision. An organ identity conditions a shared CT encoder, while organ-specific distillation and anatomy-mask supervision shape features for anatomy-weighted pooling into organ-specific representations. At inference, the shared model produces 11 organ-specific representations without external segmentation masks. We evaluate OrganLens on CT-RATE, RAD-ChestCT, INSPECT, and NLST across diverse acquisitions and downstream evaluations. Relative to CT-pretrained DINOv2, heart representations raise CT-RATE cardiomegaly AUROC from 0.910 to 0.953, while lung representations improve the Harrell C-index for NLST lung-cancer mortality by 14.2\%. The global representation reaches INSPECT Recall@10 of 33.09\% and 32.04\% for text-to-image and image-to-text retrieval, respectively. Across organ-related tasks, anatomically matched representations provide stronger task-relevant signal, while the global representation retains broad utility. OrganLens offers a scalable approach to organ-specific CT representation learning with a shared encoder. More broadly, it provides the medical research community with a reusable framework for studying organ-specific disease across cohorts and clinical endpoints.

cs.CV

Splatshot: 3D Face Avatar Generation from a Single Unconstrained Photo

Reconstructing a photorealistic 3D face avatar from a single unconstrained photograph is challenging: feed-forward 3D Gaussian Splatting (3DGS) models degrade on out-of-distribution inputs, while pretrained diffusion models produce high-fidelity images but lack multi-view consistency. We observe that these paradigms are fundamentally complementary: explicit 3D representations guarantee geometric consistency, whereas 2D diffusion priors ensure photorealism. Building on this, we propose SplatShot, a training-free framework that couples these representations directly within the denoising process. Given a base 3DGS face model and a single reference image, we jointly denoise all target views using a per-step 3D feedback loop. At each timestep, we predict clean images from the noisy latents, refit the 3DGS to these multi-view predictions, and back-propagate the photometric discrepancy between the 3DGS re-renderings and 2D predictions into the noise estimate. This steers the sampling trajectory toward strictly 3D-coherent, identity-faithful outputs. Experiments on diverse in-the-wild images demonstrate that SplatShot produces 3D avatars with superior identity preservation, photorealism, and multi-view consistency.

cs.CV

FastAvatar: Instant 3D Gaussian Splatting for Faces from Single Unconstrained Poses

We present FastAvatar, a fast and robust algorithm for single-image 3D face reconstruction using 3D Gaussian Splatting (3DGS). Given a single input image from an arbitrary pose, FastAvatar recovers a high-quality, full-head 3DGS avatar in approximately 3 seconds on a single NVIDIA A100 GPU. We use a two-stage design: a feed-forward encoder-decoder predicts coarse face geometry by regressing Gaussian structure from a pose-invariant identity embedding, and a lightweight test-time refinement stage then optimizes the appearance parameters for photorealistic rendering. This hybrid strategy combines the speed and stability of direct prediction with the accuracy of optimization, enabling strong identity preservation even under extreme input poses. FastAvatar achieves state-of-the-art reconstruction quality (24.01 dB PSNR, 0.91 SSIM) while running over 600x faster than existing per-subject optimization methods (e.g., FlashAvatar, GaussianAvatars, GASP). Once reconstructed, our avatars support photorealistic novel-view synthesis and FLAME-guided expression animation, enabling controllable reenactment from a single image. By jointly offering high fidelity, robustness to pose, and rapid reconstruction, FastAvatar significantly broadens the applicability of 3DGS-based facial avatars.

cs.CV