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Zhiyu Ye

Publications and source records attributed to Zhiyu Ye.

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MCSeg: Pre-training and Fine-tuning Volumetric Pyramid Transformer for Multi-modal Cardiac Image Segmentation

Automatic cardiac image segmentation is pivotal for diagnosing and treating cardiac diseases. In this work, we introduce MCSeg, a volumetric transformer-based network tailored for multi-modal cardiac segmentation. To overcome the architectural mismatch inherent in existing hybrid networks, we propose a novel Scaling Feature Pyramid (SFP). Unlike conventional skip connections, the SFP effectively bridges the single-scale 3D Vision Transformer (ViT) encoder and the multi-scale CNN decoder by transforming the ViT's output into a hierarchical feature pyramid, ensuring that global contextual information is effectively leveraged. For the training paradigm, the ViT encoder first undergoes self-supervised pre-training via masked image modeling. Subsequently, the network is fine-tuned on downstream tasks, during which a regional mutual information (RMI) loss is integrated to improve boundary segmentation accuracy. In experiments, MCSeg consistently outperforms eleven SOTA methods on CT dataset ImageCHD, multi-modal dataset MM-WHS, MRI dataset HVSMR-2.0 and MSD Heart, highlighting the effectiveness of our MCSeg for multi-modal cardiac segmentation tasks. Furthermore, MCSeg's superior performance in few-shot experiment showcases its significant potential in adapting to limited data scenarios. Codes and pre-trained ViT-B weights are open-sourced at https://openi.pcl.ac.cn/OpenMedIA/MCSeg

cs.CV

A multicenter benchmark and clinically structured metric for coronary CTA report generation

Reliable evaluation of automated coronary computed tomography angiography (CCTA) report generation requires standardized multicentre benchmarks and clinically structured metrics. We established a four-centre benchmark comprising 3,021 CCTA series from 818 patient-report pairs to evaluate seven open-source three-dimensional vision-language models. We developed CSM$_{\text{CCTA}}$, a clinically structured metric for CCTA report evaluation, with patient-, vessel-, and segment-level variables defined according to clinical guidelines. Report pairs are compared at the finest shared anatomical level, and the contributions of different clinical components are weighted based on expert assessments. We estimated these weights using 70 expert-scored cases and evaluated clinical alignment in a non-overlapping set of 30 cases. CSM$_{\text{CCTA}}$ showed a strong correlation with radiologist scores (Pearson's $r=0.97$, $p<0.001$), exceeding the next-best metric, FORTE ($r=0.70$), by 0.27, and agreed with expert preferences in 115 of 160 pairwise comparisons (71.9\%). Under controlled perturbations, CSM$_{\text{CCTA}}$ remained stable to clinically equivalent wording and decreased monotonically with progressive information omission. In the multicenter benchmark, the CCTA-trained C2RG model achieved the highest CSM$_{\text{CCTA}}$ scores across all four hospitals, although its performance remained far from optimal. In contrast, CCTA-irrelevant reports accounted for up to 98.7\% of the outputs from generalist models. Together, the benchmark provides a standardized setting for model comparison, while CSM$_{\text{CCTA}}$ enables clinically structured evaluation of finding agreement and anatomical specificity. These results support a more clinically aligned and anatomically resolved approach to evaluating CCTA report generation. Code is available at https://openi.pcl.ac.cn/OpenMedIA/CSM_CCTA.

cs.CV

Efficient Universal Models for Medical Image Segmentation via Weakly Supervised In-Context Learning

Universal models for medical image segmentation, such as interactive and in-context learning (ICL) models, offer strong generalization but require extensive annotations. Interactive models need repeated user prompts for each image, while ICL relies on dense, pixel-level labels. To address this, we propose Weakly Supervised In-Context Learning (WS-ICL), a new ICL paradigm that leverages weak prompts (e.g., bounding boxes or points) instead of dense labels for context. This approach significantly reduces annotation effort by eliminating the need for fine-grained masks and repeated user prompting for all images. We evaluated the proposed WS-ICL model on three held-out benchmarks. Experimental results demonstrate that WS-ICL achieves performance comparable to regular ICL models at a significantly lower annotation cost. In addition, WS-ICL is highly competitive even under the interactive paradigm. These findings establish WS-ICL as a promising step toward more efficient and unified universal models for medical image segmentation. Our code and model are publicly available at https://github.com/jiesihu/Weak-ICL.

cs.CV

Towards Robust In-Context Learning for Medical Image Segmentation via Data Synthesis

The rise of In-Context Learning (ICL) for universal medical image segmentation has introduced an unprecedented demand for large-scale, diverse datasets for training, exacerbating the long-standing problem of data scarcity. While data synthesis offers a promising solution, existing methods often fail to simultaneously achieve both high data diversity and a domain distribution suitable for medical data. To bridge this gap, we propose \textbf{SynthICL}, a novel data synthesis framework built upon domain randomization. SynthICL ensures realism by leveraging anatomical priors from real-world datasets, generates diverse anatomical structures to cover a broad data distribution, and explicitly models inter-subject variations to create data cohorts suitable for ICL. Extensive experiments on four held-out datasets validate our framework's effectiveness, showing that models trained with our data achieve performance gains of up to 63\% in average Dice and substantially enhanced generalization to unseen anatomical domains. Our work helps mitigate the data bottleneck for ICL-based segmentation, paving the way for robust models. Our code and the generated dataset are publicly available at https://github.com/jiesihu/Neuroverse3D.

cs.CV

Improving Medical Report Generation with Adapter Tuning and Knowledge Enhancement in Vision-Language Foundation Models

Medical report generation demands automatic creation of coherent and precise descriptions for medical images. However, the scarcity of labelled medical image-report pairs poses formidable challenges in developing large-scale neural networks capable of harnessing the potential of artificial intelligence, exemplified by large language models. This study builds upon the state-of-the-art vision-language pre-training and fine-tuning approach, BLIP-2, to customize general large-scale foundation models. Integrating adapter tuning and a medical knowledge enhancement loss, our model significantly improves accuracy and coherence. Validation on the dataset of ImageCLEFmedical 2023 demonstrates our model's prowess, achieving the best-averaged results against several state-of-the-art methods. Significant improvements in ROUGE and CIDEr underscore our method's efficacy, highlighting promising outcomes for the rapid medical-domain adaptation of the vision-language foundation models in addressing challenges posed by data scarcity.

cs.CV