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Zhiyuan Zhu

Publications and source records attributed to Zhiyuan Zhu.

25 records · Page 2Linked to original sources

MReg: A Novel Regression Model with MoE-based Video Feature Mining for Mitral Regurgitation Diagnosis

Color Doppler echocardiography is a crucial tool for diagnosing mitral regurgitation (MR). Recent studies have explored intelligent methods for MR diagnosis to minimize user dependence and improve accuracy. However, these approaches often fail to align with clinical workflow and may lead to suboptimal accuracy and interpretability. In this study, we introduce an automated MR diagnosis model (MReg) developed on the 4-chamber cardiac color Doppler echocardiography video (A4C-CDV). It follows comprehensive feature mining strategies to detect MR and assess its severity, considering clinical realities. Our contribution is threefold. First, we formulate the MR diagnosis as a regression task to capture the continuity and ordinal relationships between categories. Second, we design a feature selection and amplification mechanism to imitate the sonographer's diagnostic logic for accurate MR grading. Third, inspired by the Mixture-of-Experts concept, we introduce a feature summary module to extract the category-level features, enhancing the representational capacity for more accurate grading. We trained and evaluated our proposed MReg on a large in-house A4C-CDV dataset comprising 1868 cases with three graded regurgitation labels. Compared to other weakly supervised video anomaly detection and supervised classification methods, MReg demonstrated superior performance in MR diagnosis. Our code is available at: https://github.com/cskdstz/MReg.

cs.CV↗

Hierarchical Corpus-View-Category Refinement for Carotid Plaque Risk Grading in Ultrasound

Accurate carotid plaque grading (CPG) is vital to assess the risk of cardiovascular and cerebrovascular diseases. Due to the small size and high intra-class variability of plaque, CPG is commonly evaluated using a combination of transverse and longitudinal ultrasound views in clinical practice. However, most existing deep learning-based multi-view classification methods focus on feature fusion across different views, neglecting the importance of representation learning and the difference in class features. To address these issues, we propose a novel Corpus-View-Category Refinement Framework (CVC-RF) that processes information from Corpus-, View-, and Category-levels, enhancing model performance. Our contribution is four-fold. First, to the best of our knowledge, we are the foremost deep learning-based method for CPG according to the latest Carotid Plaque-RADS guidelines. Second, we propose a novel center-memory contrastive loss, which enhances the network's global modeling capability by comparing with representative cluster centers and diverse negative samples at the Corpus level. Third, we design a cascaded down-sampling attention module to fuse multi-scale information and achieve implicit feature interaction at the View level. Finally, a parameter-free mixture-of-experts weighting strategy is introduced to leverage class clustering knowledge to weight different experts, enabling feature decoupling at the Category level. Experimental results indicate that CVC-RF effectively models global features via multi-level refinement, achieving state-of-the-art performance in the challenging CPG task.

cs.CV↗

TCSinger 2: Customizable Multilingual Zero-shot Singing Voice Synthesis

Customizable multilingual zero-shot singing voice synthesis (SVS) has various potential applications in music composition and short video dubbing. However, existing SVS models overly depend on phoneme and note boundary annotations, limiting their robustness in zero-shot scenarios and producing poor transitions between phonemes and notes. Moreover, they also lack effective multi-level style control via diverse prompts. To overcome these challenges, we introduce TCSinger 2, a multi-task multilingual zero-shot SVS model with style transfer and style control based on various prompts. TCSinger 2 mainly includes three key modules: 1) Blurred Boundary Content (BBC) Encoder, predicts duration, extends content embedding, and applies masking to the boundaries to enable smooth transitions. 2) Custom Audio Encoder, uses contrastive learning to extract aligned representations from singing, speech, and textual prompts. 3) Flow-based Custom Transformer, leverages Cus-MOE, with F0 supervision, enhancing both the synthesis quality and style modeling of the generated singing voice. Experimental results show that TCSinger 2 outperforms baseline models in both subjective and objective metrics across multiple related tasks. Singing voice samples are available at https://aaronz345.github.io/TCSinger2Demo/.

eess.AS↗

FetalFlex: Anatomy-Guided Diffusion Model for Flexible Control on Fetal Ultrasound Image Synthesis

Fetal ultrasound (US) examinations require the acquisition of multiple planes, each providing unique diagnostic information to evaluate fetal development and screening for congenital anomalies. However, obtaining a comprehensive, multi-plane annotated fetal US dataset remains challenging, particularly for rare or complex anomalies owing to their low incidence and numerous subtypes. This poses difficulties in training novice radiologists and developing robust AI models, especially for detecting abnormal fetuses. In this study, we introduce a Flexible Fetal US image generation framework (FetalFlex) to address these challenges, which leverages anatomical structures and multimodal information to enable controllable synthesis of fetal US images across diverse planes. Specifically, FetalFlex incorporates a pre-alignment module to enhance controllability and introduces a repaint strategy to ensure consistent texture and appearance. Moreover, a two-stage adaptive sampling strategy is developed to progressively refine image quality from coarse to fine levels. We believe that FetalFlex is the first method capable of generating both in-distribution normal and out-of-distribution abnormal fetal US images, without requiring any abnormal data. Experiments on multi-center datasets demonstrate that FetalFlex achieved state-of-the-art performance across multiple image quality metrics. A reader study further confirms the close alignment of the generated results with expert visual assessments. Furthermore, synthetic images by FetalFlex significantly improve the performance of six typical deep models in downstream classification and anomaly detection tasks. Lastly, FetalFlex's anatomy-level controllable generation offers a unique advantage for anomaly simulation and creating paired or counterfactual data at the pixel level. The demo is available at: https://dyf1023.github.io/FetalFlex/.

eess.IV↗

Drawing the Line: Enhancing Trustworthiness of MLLMs Through the Power of Refusal

Multimodal large language models (MLLMs) excel at multimodal perception and understanding, yet their tendency to generate hallucinated or inaccurate responses undermines their trustworthiness. Existing methods have largely overlooked the importance of refusal responses as a means of enhancing MLLMs reliability. To bridge this gap, we present the Information Boundary-aware Learning Framework (InBoL), a novel approach that empowers MLLMs to refuse to answer user queries when encountering insufficient information. To the best of our knowledge, InBoL is the first framework that systematically defines the conditions under which refusal is appropriate for MLLMs using the concept of information boundaries proposed in our paper. This framework introduces a comprehensive data generation pipeline and tailored training strategies to improve the model's ability to deliver appropriate refusal responses. To evaluate the trustworthiness of MLLMs, we further propose a user-centric alignment goal along with corresponding metrics. Experimental results demonstrate a significant improvement in refusal accuracy without noticeably compromising the model's helpfulness, establishing InBoL as a pivotal advancement in building more trustworthy MLLMs.

cs.CL↗

Recoil-ion momentum spectroscopy of photoionization of cold rubidium atoms in a strong laser field

We study photoionization of cold rubidium atoms in a strong infrared laser field using a magneto-optical trap (MOT) recoil ion momentum spectrometer. Three types of cold rubidium target are provided, operating in two-dimension (2D) MOT, 2D molasses, and 3D MOT with densities in the orders of $10^7$ atoms/cm$^3$, $10^8$ atoms/cm$^3$, and $10^9$ atoms/cm$^3$, respectively. The density profile and the temperature of 3D MOT are characterized using the absorption imaging and photoionization. The momentum distributions of Rb$^+$ created by absorption of two- or three-photon illuminate a dipole-like double-peak structure, in good agreement with the results in the strong field approximation. The yielding momentum resolution of $0.12 \pm 0.03$ a.u. is achieved in comparison with theoretical calculations, exhibiting the great prospects for the study of electron correlations in alkali metal atoms through interaction with strong laser pulses.

quant-ph↗

Dielectric response of soft mode in ferroelectric SrTiO3

We report far-infrared dielectric properties of powder form ferroelectric SrTiO3. Terahertz time-domain spectroscopy (THz-TDS) measurement reveals that the low-frequency dielectric response of SrTiO3 is a consequence of the lowest transverse optical (TO) soft mode TO1 at 2.70 THz (90.0 1/cm), which is directly verified by Raman spectroscopy. This result provides a better understanding of the relation of low-frequency dielectric function with the optical phonon soft mode for ferroelectric materials. Combining THz-TDS with Raman spectra, the overall low-frequency optical phonon response of SrTiO3 is presented in an extended spectral range from 6.7 1/cm to 1000.0 1/cm.

cond-mat.mtrl-sci↗