arXiv subjects

Zhonghua Lu

Publications and source records attributed to Zhonghua Lu.

6 recordsLinked to original sources

arXiv2026

DeepTCM1.0: A Multi-Expert AI Agent for Deciphering Mechanisms of Chinese Herbal Formulae Based on General Large Language Models

Background: Mechanistic elucidation of traditional Chinese medicine (TCM) compound formulas remains a central challenge in the modernization of TCM. Conventional approaches, including data mining and network pharmacology, are insufficient for achieving deep integration between classical TCM theory and modern scientific research. In addition, direct question-answering using general-purpose artificial intelligence large language models is limited by inadequate adaptation to TCM theoretical frameworks and susceptibility to reasoning hallucinations. Consequently, there is an urgent need to develop intelligent analytical methods aligned with the holistic principles of TCM. Objective: To establish a multi-expert intelligent agent framework integrating classical TCM theory with modern life sciences, thereby enabling systematic and interpretable mechanistic analysis of TCM compound formulas, with Guizhi Decoction serving as a representative validation case. Methods: The DeepTCM1.0 framework was constructed based on the general-purpose large language model DeepSeek V3.2. It adopts a three-tier collaborative architecture and a three-round iterative quality-control workflow, simulating the collaborative analytical process of 11 interdisciplinary intelligent agents. The framework was applied to the mechanistic interpretation of Guizhi Decoction from the dual perspectives of classical traditional Chinese medicine theory and modern scientific research. Framework performance was comprehensively evaluated through double-blind five-dimensional scoring, intraclass correlation coefficient (ICC) reliability testing, Mann-Whitney U tests, and effect size analysis. The evaluation employed four independent large language models as evaluators, each conducting five rounds of repeated scoring on five anonymized reports, resulting in a total of 100 independent scoring assessments.

cs.CL↗

arXiv2025

FlashMP: Fast Discrete Transform-Based Solver for Preconditioning Maxwell's Equations on GPUs

Efficiently solving large-scale linear systems is a critical challenge in electromagnetic simulations, particularly when using the Crank-Nicolson Finite-Difference Time-Domain (CN-FDTD) method. Existing iterative solvers are commonly employed to handle the resulting sparse systems but suffer from slow convergence due to the ill-conditioned nature of the double-curl operator. Approximate preconditioners, like Successive Over-Relaxation (SOR) and Incomplete LU decomposition (ILU), provide insufficient convergence, while direct solvers are impractical due to excessive memory requirements. To address this, we propose FlashMP, a novel preconditioning system that designs a subdomain exact solver based on discrete transforms. FlashMP provides an efficient GPU implementation that achieves multi-GPU scalability through domain decomposition. Evaluations on AMD MI60 GPU clusters (up to 1000 GPUs) show that FlashMP reduces iteration counts by up to 16x and achieves speedups of 2.5x to 4.9x compared to baseline implementations in state-of-the-art libraries such as Hypre. Weak scalability tests show parallel efficiencies up to 84.1%.

cs.DC↗

arXiv2025

HRFT: Mining High-Frequency Risk Factor Collections End-to-End via Transformer

In quantitative trading, transforming historical stock data into interpretable, formulaic risk factors enhances the identification of market volatility and risk. Despite recent advancements in neural networks for extracting latent risk factors, these models remain limited to feature extraction and lack explicit, formulaic risk factor designs. By viewing symbolic mathematics as a language where valid mathematical expressions serve as meaningful "sentences" we propose framing the task of mining formulaic risk factors as a language modeling problem. In this paper, we introduce an end to end methodology, Intraday Risk Factor Transformer (IRFT), to directly generate complete formulaic risk factors, including constants. We use a hybrid symbolic numeric vocabulary where symbolic tokens represent operators and stock features, and numeric tokens represent constants. We train a Transformer model on high frequency trading (HFT) datasets to generate risk factors without relying on a predefined skeleton of operators. It determines the general form of the stock volatility law, including constants. We refine the predicted constants using the Broyden Fletcher Goldfarb Shanno (BFGS) algorithm to mitigate non linear issues. Compared to the ten approaches in SRBench, an active benchmark for symbolic regression (SR), IRFT achieves a 30% higher investment return on the HS300 and SP500 datasets, while achieving inference times that are orders of magnitude faster than existing methods in HF risk factor mining tasks.

cs.CE↗

arXiv2025

Mining Intraday Risk Factor Collections via Hierarchical Reinforcement Learning based on Transferred Options

Traditional risk factors like beta, size/value, and momentum often lag behind market dynamics in measuring and predicting stock return volatility. Statistical models like PCA and factor analysis fail to capture hidden nonlinear relationships. Genetic programming (GP) can identify nonlinear factors but often lacks mechanisms for evaluating factor quality, and the resulting formulas are complex. To address these challenges, we propose a Hierarchical Proximal Policy Optimization (HPPO) framework for automated factor generation and evaluation. HPPO uses two PPO models: a high-level policy assigns weights to stock features, and a low-level policy identifies latent nonlinear relationships. The Pearson correlation between generated factors and return volatility serves as the reward signal. Transfer learning pre-trains the high-level policy on large-scale historical data, fine-tuning it with the latest data to adapt to new features and shifts. Experiments show the HPPO-TO algorithm achieves a 25\% excess return in HFT markets across China (CSI 300/800), India (Nifty 100), and the US (S\&P 500). Code and data are available at https://github.com/wencyxu/HRL-HF_risk_factor_set.

cs.CE↗

arXiv2025

Learning Explainable Stock Predictions with Tweets Using Mixture of Experts

Stock price movements are influenced by many factors, and alongside historical price data, tex-tual information is a key source. Public news and social media offer valuable insights into market sentiment and emerging events. These sources are fast-paced, diverse, and significantly impact future stock trends. Recently, LLMs have enhanced financial analysis, but prompt-based methods still have limitations, such as input length restrictions and difficulties in predicting sequences of varying lengths. Additionally, most models rely on dense computational layers, which are resource-intensive. To address these challenges, we propose the FTS- Text-MoE model, which combines numerical data with key summaries from news and tweets using point embeddings, boosting prediction accuracy through the integration of factual textual data. The model uses a Mixture of Experts (MoE) Transformer decoder to process both data types. By activating only a subset of model parameters, it reduces computational costs. Furthermore, the model features multi-resolution prediction heads, enabling flexible forecasting of financial time series at different scales. Experimental results show that FTS-Text-MoE outperforms baseline methods in terms of investment returns and Sharpe ratio, demonstrating its superior accuracy and ability to predict future market trends.

cs.CE↗

arXiv2020

CNNPruner: Pruning Convolutional Neural Networks with Visual Analytics

Convolutional neural networks (CNNs) have demonstrated extraordinarily good performance in many computer vision tasks. The increasing size of CNN models, however, prevents them from being widely deployed to devices with limited computational resources, e.g., mobile/embedded devices. The emerging topic of model pruning strives to address this problem by removing less important neurons and fine-tuning the pruned networks to minimize the accuracy loss. Nevertheless, existing automated pruning solutions often rely on a numerical threshold of the pruning criteria, lacking the flexibility to optimally balance the trade-off between model size and accuracy. Moreover, the complicated interplay between the stages of neuron pruning and model fine-tuning makes this process opaque, and therefore becomes difficult to optimize. In this paper, we address these challenges through a visual analytics approach, named CNNPruner. It considers the importance of convolutional filters through both instability and sensitivity, and allows users to interactively create pruning plans according to a desired goal on model size or accuracy. Also, CNNPruner integrates state-of-the-art filter visualization techniques to help users understand the roles that different filters played and refine their pruning plans. Through comprehensive case studies on CNNs with real-world sizes, we validate the effectiveness of CNNPruner.

cs.CV↗