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Zhou Yuan

Publications and source records attributed to Zhou Yuan.

4 recordsLinked to original sources

HuBMAP Data Portal: a resource for multimodal spatial and single-cell data of healthy human tissues

The NIH Human BioMolecular Atlas Program (HuBMAP) Data Portal (https://portal.hubmapconsortium.org/) serves as a comprehensive repository for multimodal, multi-scale spatial and single-cell data from healthy human tissues. As of August 2026, the portal hosts 9,316 public datasets from 26 data types spanning 29 organ classes across 501 donors. Portal infrastructure and user interfaces support data search and discovery, visualization, and analysis directly in web browsers. These capabilities include metadata- and data-driven search, collaborative Workspaces with access to high-performance compute, and interactive Vitessce visualizations across non-spatial, 2D, and 3D spatial datasets. Data-type-specific uniform processing pipelines and rigorous quality control processes ensure comparability of results across laboratories, organs, and donors, while externally processed community-contributed datasets provide complementary perspectives. Here we describe portal functionality, infrastructure, and design, and highlight its role as a platform for large-scale spatial single-cell research across diverse data types, organs, and scales.

q-bio.QM

Advancing DRL Agents in Commercial Fighting Games: Training, Integration, and Agent-Human Alignment

Deep Reinforcement Learning (DRL) agents have demonstrated impressive success in a wide range of game genres. However, existing research primarily focuses on optimizing DRL competence rather than addressing the challenge of prolonged player interaction. In this paper, we propose a practical DRL agent system for fighting games named Shūkai, which has been successfully deployed to Naruto Mobile, a popular fighting game with over 100 million registered users. Shūkai quantifies the state to enhance generalizability, introducing Heterogeneous League Training (HELT) to achieve balanced competence, generalizability, and training efficiency. Furthermore, Shūkai implements specific rewards to align the agent's behavior with human expectations. Shūkai's ability to generalize is demonstrated by its consistent competence across all characters, even though it was trained on only 13% of them. Additionally, HELT exhibits a remarkable 22% improvement in sample efficiency. Shūkai serves as a valuable training partner for players in Naruto Mobile, enabling them to enhance their abilities and skills.

cs.AI

Dynamic Interference Minimization Routing Game for On-Demand Cognitive Pilot Channel

In this paper, we introduce a distributed dynamic routing algorithm for secondary users (SUs) to minimize their interference with the primary users (PUs) in multi-hop cognitive radio (CR) networks. We use the medial axis with a relaxation factor as a reference path which is contingent on the states of the PUs. Along the axis, we construct a hierarchical structure for multiple sources to reach cognitive pilot channel (CPC) base stations. We use a temporal and spatial dynamic non-cooperative game to model the interactions among SUs as well as their influences from PUs in the multi-hop structure of the network. A multi-stage fictitious play learning is used for distributed routing in multi-hop CR networks. We obtain a set of mixed (behavioral) Nash equilibrium strategies of the dynamic game in closed form by backward induction. The proposed algorithm minimizes the overall interference and the average packet delay along the routing path from SU nodes to CPC base stations in an optimal and distributed manner

cs.GT

Theoretical Analysis of Cyclic Frequency Domain Noise and Feature Detection for Cognitive Radio Systems

In cognitive radio systems, cyclostationary feature detection plays an important role in spectrum sensing, especially in low SNR cases. To configure the detection threshold under a certain noise level and a pre-set miss detection probability Pf, it's important to derive the theoretical distribution of the observation variable. In this paper, noise distribution in cyclic frequency domain has been studied and Generalized Extreme Value (GEV) distribution is found to be a precise match. Maximum likelihood estimation is applied to estimate the parameters of GEV. Monte Carlo simulation has been carried out to show that the simulated ROC curve is coincided with the theoretical ROC curve, which proves the efficiency of the theoretical distribution model.

cs.IT