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Zihan Nie

Publications and source records attributed to Zihan Nie.

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QuantumMind: Constraint-Grounded Agentic Reasoning for Speedup Analysis in Quantum Computing

Identifying a meaningful quantum speedup requires more than matching a classical problem to a familiar quantum primitive: the claim must preserve the task, respect access and output models, expose required promises, and remain within a defensible complexity scope. We present QuantumMind, an auditable agentic workflow for generating and conservatively screening quantum-acceleration hypotheses. A fixed sequence of typed, role-specialized actions formalizes the public task, analyzes structure and classical bottlenecks, matches a source-linked registry of quantum primitives and barriers, and constructs a scoped candidate scheme. A deterministic ten-check validator assigns the authoritative verdict; completed states are compiled into a Quantum Acceleration Evidence Graph and passed through a downward-only research screen that cannot strengthen the decision. We evaluate QuantumMind against seven task-adapted prompting and agentic controls on 582 identical open-discovery tasks. Under the frozen Open-Discovery Score (ODS), QuantumMind obtains 53.1 mean ODS, exceeding the strongest baseline by 17.3 points (48.2% relative), and wins 355 of 582 paired tasks against that baseline. It passes the graph audit on 99.8% of tasks, compared with 43.6% for the strongest baseline, and ranks first in all seven task families. The results indicate that typed state transitions and deterministic evidence control contribute beyond fluent generation alone.

cs.AI

ReMoE: Report-Guided Mixture-of-Experts for Multimodal OCT/OCTA Anomaly Detection

Multimodal medical anomaly detection identifies samples deviating from normal patterns, where scarce abnormal cases make normality modeling from normal data practical. In retinal Optical Coherence Tomography (OCT) and OCT Angiography (OCTA) anomaly detection, existing unsupervised methods rely on visual feature distributions, reconstruction residuals, or encoder-decoder discrepancies, making anomaly scores depend on appearance-level deviations, while multimodal normality also contains semantic organization described in normal medical reports. To this end, we propose Report-Guided Mixture-of-Experts (ReMoE), which distills normal report semantics into an image-to-text prior student, builds modality-aware priors, and uses Report-Guided Modality Modulation (RMM) to modulate features through mixture-of-experts routing. Experiments on a private OCT/OCTA dataset with paired normal reports and a public OCTA500-3MM setting using a fixed normal report demonstrate state-of-the-art performance.

cs.CV

CFR-Net:Collaborative Feature Refinement Network for Medical Image Anomaly Detection

Medical image anomaly detection remains challenging because networks pretrained on natural images often exhibit limited adaptability to medical images, where abnormal patterns appear as fine-grained local shifts, multi-scale contextual mismatches, and orientation-sensitive structural deviations. To address this, we propose the Collaborative Feature Refinement Network (CFR-Net), which combines shared teacher-student feature refinement before decoding with cross-space consistency after decoding. CFR-Net refines frozen teacher features and trainable student features using a Multi-Path Feature Refinement Module (MPFRM) with shared parameters, imposing common multi-path refinement rules on generic visual references and representations adapted to the medical domain, thereby mitigating domain discrepancy while modeling local, multi-scale, and orientation-sensitive feature characteristics. A variance-sensitive objective and dynamic ''homework set'' reorganization further support layer-adaptive consistency learning. Experiments on medical benchmarks show that CFR-Net achieves competitive anomaly classification and strong anomaly localization performance when trained on normal data.

cs.CV

Can Multimodal Large Language Models Understand OCT?

Optical coherence tomography (OCT) imaging is essential for the diagnosis and treatment of retinal diseases. Although multimodal large language models (MLLMs) have demonstrated considerable potential in medical image analysis, existing benchmarks largely reduce OCT understanding to coarse-grained disease classification or isolated visual question answering, leaving the complete cognitive process from visual perception to clinical reasoning insufficiently evaluated. To address this limitation, we introduce OCT-Bench, a comprehensive benchmark dedicated to OCT image understanding. OCT-Bench comprises 10,076 high-quality multiple-choice questions constructed from 4,137 OCT images across seven public datasets. Following the real-world clinical interpretation workflow, we establish a hierarchical capability taxonomy consisting of 20 fine-grained tasks across three dimensions: Perception, Cognition, and Reasoning. These tasks cover a broad range of capabilities, including imaging attributes, retinal anatomy, lesion characteristics, spatial relationships, disease assessment, therapeutic decision-making, and prognostic management. We systematically evaluate 20 representative MLLMs, including proprietary models, open-source general-purpose models, and medical-domain models. Experimental results demonstrate that current models remain substantially short of reliable OCT understanding. Moreover, neither medical-domain adaptation nor increased model scale consistently improves performance across capability levels. OCT-Bench enables comprehensive and fine-grained evaluation of MLLMs, providing a foundation for identifying capability bottlenecks and advancing clinically grounded OCT understanding.

cs.CV

FinSurvival: A Suite of Large Scale Survival Modeling Tasks from Finance

Survival modeling predicts the time until an event occurs and is widely used in risk analysis; for example, it's used in medicine to predict the survival of a patient based on censored data. There is a need for large-scale, realistic, and freely available datasets for benchmarking artificial intelligence (AI) survival models. In this paper, we derive a suite of 16 survival modeling tasks from publicly available transaction data generated by lending of cryptocurrencies in Decentralized Finance (DeFi). Each task was constructed using an automated pipeline based on choices of index and outcome events. For example, the model predicts the time from when a user borrows cryptocurrency coins (index event) until their first repayment (outcome event). We formulate a survival benchmark consisting of a suite of 16 survival-time prediction tasks (FinSurvival). We also automatically create 16 corresponding classification problems for each task by thresholding the survival time using the restricted mean survival time. With over 7.5 million records, FinSurvival provides a suite of realistic financial modeling tasks that will spur future AI survival modeling research. Our evaluation indicated that these are challenging tasks that are not well addressed by existing methods. FinSurvival enables the evaluation of AI survival models applicable to traditional finance, industry, medicine, and commerce, which is currently hindered by the lack of large public datasets. Our benchmark demonstrates how AI models could assess opportunities and risks in DeFi. In the future, the FinSurvival benchmark pipeline can be used to create new benchmarks by incorporating more DeFi transactions and protocols as the use of cryptocurrency grows.

q-fin.ST