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Zipei Wang

Publications and source records attributed to Zipei Wang.

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Volumetric Radiology AI in the Era of Multimodal Large Language Models

Advances in multimodal large language models (MLLMs) are extending radiological artificial intelligence (AI) beyond task-specific image analysis toward multimodal understanding and reasoning. Volumetric radiology, however, presents a fundamental representational mismatch: clinical interpretation often requires full-volume spatial context and acquisition-dependent quantitative information, whereas current MLLMs are commonly conditioned on selected two-dimensional (2D) images, compressed visual representations, or report-derived text. Reliable volumetric radiology AI therefore requires representations that preserve task-relevant three-dimensional (3D) information and systems that can access, verify, and integrate this information across clinical workflows. In this Review, we examine more than 200 publications through July 2026. We organize the literature around volumetric representation and multimodal understanding at the model level, agentic orchestration at the system level, and their links to clinical applications and evaluation. We review volumetric foundation models, language alignment and compression strategies, and agentic systems that extend MLLMs through planning, tools, memory, and workflow interaction. We distinguish settings in which selected 2D views or report-mediated reasoning may suffice from those that warrant native volumetric modeling. We also introduce a Claim-Design-Validation framework to assess whether technical, workflow, and clinical claims are matched by appropriate design and validation. Across the literature, native volumetric modeling and agentic capabilities depend on the spatial, quantitative, contextual, and workflow requirements of the intended task. Clinical credibility requires faithful volumetric representation, traceable system behavior, claim-aligned validation, and clearly defined human oversight in realistic workflows.

cs.AI

Towards Autonomous and Auditable Medical Imaging Model Development

Large language model (LLM) agents are beginning to automate machine learning engineering (MLE) by coupling planning, code execution, debugging, and empirical feedback. Translating this capability to medical imaging remains difficult because each task imposes modality-specific experimentation and strict requirements for validation protocols and prediction artifacts. Here we introduce AMID, an autonomous multi-agent framework for medical imaging model development. AMID first proposes Data-Conditioned Method Planning, which refines coarse task-level search spaces into executable, parallelizable method lanes grounded in task-specific data analysis and runnable medical-imaging resources. It then develops Verification-Guided Two-Stage Optimization, moving from broad early exploration of diverse method lanes to selective exploitation of promising candidates while enforcing strict verification of validation protocols, metric computation, and prediction artifacts throughout the optimization. Across 20 medical imaging challenge tasks spanning diverse modalities and prediction types, AMID outperformed evaluated general-purpose MLE systems and, on several tasks, approached or matched strong human-designed challenge solutions. These results suggest that AMID can turn task-specific medical imaging model development from bespoke manual engineering into an agentic workflow for producing high-performing and auditable model artifacts across heterogeneous tasks.

cs.CV

Synergizing Discriminative Exemplars and Self-Refined Experience for MLLM-based In-Context Learning in Medical Diagnosis

General Multimodal Large Language Models (MLLMs) often underperform in capturing domain-specific nuances in medical diagnosis, trailing behind fully supervised baselines. Although fine-tuning provides a remedy, the high costs of expert annotation and massive computational overhead limit its scalability. To bridge this gap without updating the weights of the pre-trained backbone of the MLLM, we propose a Clinician Mimetic Workflow. This is a novel In-Context Learning (ICL) framework designed to synergize Discriminative Exemplar Coreset Selection (DECS) and Self-Refined Experience Summarization (SRES). Specifically, DECS simulates a clinician's ability to reference "anchor cases" by selecting discriminative visual coresets from noisy data at the computational level; meanwhile, SRES mimics the cognition and reflection in clinical diagnosis by distilling diverse rollouts into a dynamic textual Experience Bank. Extensive evaluation across all 12 datasets of the MedMNIST 2D benchmark demonstrates that our method outperforms zero-shot general and medical MLLMs. Simultaneously, it achieves performance levels comparable to fully supervised vision models and domain-specific fine-tuned MLLMs, setting a new benchmark for parameter-efficient medical in-context learning. Our code is available at an anonymous repository: https://anonymous.4open.science/r/Synergizing-Discriminative-Exemplars-and-Self-Refined-Experience-ED74.

cs.CV

MLLM-Enhanced Face Forgery Detection: A Vision-Language Fusion Solution

Reliable face forgery detection algorithms are crucial for countering the growing threat of deepfake-driven disinformation. Previous research has demonstrated the potential of Multimodal Large Language Models (MLLMs) in identifying manipulated faces. However, existing methods typically depend on either the Large Language Model (LLM) alone or an external detector to generate classification results, which often leads to sub-optimal integration of visual and textual modalities. In this paper, we propose VLF-FFD, a novel Vision-Language Fusion solution for MLLM-enhanced Face Forgery Detection. Our key contributions are twofold. First, we present EFF++, a frame-level, explainability-driven extension of the widely used FaceForensics++ (FF++) dataset. In EFF++, each manipulated video frame is paired with a textual annotation that describes both the forgery artifacts and the specific manipulation technique applied, enabling more effective and informative MLLM training. Second, we design a Vision-Language Fusion Network (VLF-Net) that promotes bidirectional interaction between visual and textual features, supported by a three-stage training pipeline to fully leverage its potential. VLF-FFD achieves state-of-the-art (SOTA) performance in both cross-dataset and intra-dataset evaluations, underscoring its exceptional effectiveness in face forgery detection.

cs.CV

Image Deconvolution with Deep Image and Kernel Priors

Image deconvolution is the process of recovering convolutional degraded images, which is always a hard inverse problem because of its mathematically ill-posed property. On the success of the recently proposed deep image prior (DIP), we build an image deconvolution model with deep image and kernel priors (DIKP). DIP is a learning-free representation which uses neural net structures to express image prior information, and it showed great success in many energy-based models, e.g. denoising, super-resolution, inpainting. Instead, our DIKP model uses such priors in image deconvolution to model not only images but also kernels, combining the ideas of traditional learning-free deconvolution methods with neural nets. In this paper, we show that DIKP improve the performance of learning-free image deconvolution, and we experimentally demonstrate this on the standard benchmark of six standard test images in terms of PSNR and visual effects.

cs.CV