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Ziquan Zhu

Publications and source records attributed to Ziquan Zhu.

6 recordsLinked to original sources

CPR: Chained Perceptual Refinement for Coarse-to-Fine Medical Image Classification

High resolution medical images contain fine grained, spatially sparse cues that are critical for diagnosis, yet preserving full resolution incurs substantial computational and memory costs. Most deep models process images uniformly, leading to redundant computation or loss of diagnostic detail under downsampling. We propose Chained Perceptual Refinement, CPR, a coarse to fine framework that formulates medical image analysis as a sequential global to local decision process. Starting from a low resolution global view, CPR dynamically predicts the location and spatial extent of refinement regions, extracts high resolution evidence from the original image, and incrementally integrates it with global context. By keeping the backbone input size fixed while contracting the perceptual field, CPR preserves diagnostic fidelity with constant peak GPU memory. Extensive experiments on five medical imaging datasets and multiple backbone architectures demonstrate that CPR consistently outperforms both fixed resolution and multi scale state of the art baselines, achieving improvements of up to 2.27 percentage points over the second best method. It also achieves up to a 19.6 fold reduction in GFLOPs at matched accuracy, establishing a superior accuracy and efficiency trade off for high resolution medical image analysis. The code is available on GitHub.

cs.CV

Confusion-Aware Spectral Regularizer for Long-Tailed Recognition

Long-tailed image classification remains a long-standing challenge, as real-world data typically follow highly imbalanced distributions where a few head classes dominate and many tail classes contain only limited samples. This imbalance biases feature learning toward head categories and leads to significant degradation on rare classes. Although recent studies have proposed re-sampling, re-weighting, and decoupled learning strategies, the improvement on the most underrepresented classes still remains marginal compared with overall accuracy. In this work, we present a confusion-centric perspective for long-tailed recognition that explicitly focuses on worst-class generalization. We first establish a new theoretical framework of class-specific error analysis, which shows that the worst-class error can be tightly upper-bounded by the spectral norm of the frequency-weighted confusion matrix and a model-dependent complexity term. Guided by this insight, we propose the Confusion-Aware Spectral Regularizer (CAR) that minimizes the spectral norm of the confusion matrix during training to reduce inter-class confusion and enhance tail-class generalization. To enable stable and efficient optimization, CAR integrates a Differentiable Confusion Matrix Surrogate and an EMA-based Confusion Estimator to maintain smooth and low-variance estimates across mini-batches. Extensive experiments across multiple long-tailed benchmarks demonstrates that CAR substantially improves both worst-class accuracy and overall performance. When combined with ConCutMix augmentation, CAR consistently surpasses exisiting state-of-the-art long-tailed learning methods under both the training-from-scratch setting (by 2.37% ~ 4.83%) and the fine-tuning-from-pretrained setting (by 2.42% ~ 4.17%) across ImageNet-LT, CIFAR100-LT, and iNaturalist datasets.

cs.CE

Dual-Kernel Adapter: Expanding Spatial Horizons for Data-Constrained Medical Image Analysis

Adapters have become a widely adopted strategy for efficient fine-tuning of large pretrained models, particularly in resource-constrained settings. However, their performance under extreme data scarcity, common in medical imaging due to high annotation costs, privacy regulations, and fragmented datasets, remains underexplored. In this work, we present the first comprehensive study of adapter-based fine-tuning for large pretrained models in low-data medical imaging scenarios. We find that, contrary to their promise, conventional adapters can degrade performance under severe data constraints, performing even worse than simple linear probing when trained on less than 1% of the corresponding training data. Through systematic analysis, we identify a sharp reduction in Effective Receptive Field (ERF) as a key factor behind this degradation. Motivated by these findings, we propose the Dual-Kernel Adapter (DKA), a lightweight module that expands spatial context via large-kernel convolutions while preserving local detail with small-kernel counterparts. Extensive experiments across diverse classification and segmentation benchmarks show that DKA significantly outperforms existing adapter methods, establishing new leading results in both data-constrained and data-rich regimes.

cs.CE

LKA: Large Kernel Adapter for Enhanced Medical Image Classification

Despite the notable success of current Parameter-Efficient Fine-Tuning (PEFT) methods across various domains, their effectiveness on medical datasets falls short of expectations. This limitation arises from two key factors: (1) medical images exhibit extensive anatomical variation and low contrast, necessitating a large receptive field to capture critical features, and (2) existing PEFT methods do not explicitly address the enhancement of receptive fields. To overcome these challenges, we propose the Large Kernel Adapter (LKA), designed to expand the receptive field while maintaining parameter efficiency. The proposed LKA consists of three key components: down-projection, channel-wise large kernel convolution, and up-projection. Through extensive experiments on various datasets and pre-trained models, we demonstrate that the incorporation of a larger kernel size is pivotal in enhancing the adaptation of pre-trained models for medical image analysis. Our proposed LKA outperforms 11 commonly used PEFT methods, surpassing the state-of-the-art by 3.5% in top-1 accuracy across five medical datasets.

cs.CE

SPAM: Spike-Aware Adam with Momentum Reset for Stable LLM Training

Large Language Models (LLMs) have demonstrated exceptional performance across diverse tasks, yet their training remains highly resource-intensive and susceptible to critical challenges such as training instability. A predominant source of this instability stems from gradient and loss spikes, which disrupt the learning process, often leading to costly interventions like checkpoint recovery and experiment restarts, further amplifying inefficiencies. This paper presents a comprehensive investigation into gradient spikes observed during LLM training, revealing their prevalence across multiple architectures and datasets. Our analysis shows that these spikes can be up to $1000\times$ larger than typical gradients, substantially deteriorating model performance. To address this issue, we propose Spike-Aware Adam with Momentum Reset SPAM, a novel optimizer designed to counteract gradient spikes through momentum reset and spike-aware gradient clipping. Extensive experiments, including both pre-training and fine-tuning, demonstrate that SPAM consistently surpasses Adam and its variants across various tasks, including (1) LLM pre-training from 60M to 1B, (2) 4-bit LLM pre-training,(3) reinforcement learning, and (4) Time Series Forecasting. Additionally, SPAM facilitates memory-efficient training by enabling sparse momentum, where only a subset of momentum terms are maintained and updated. When operating under memory constraints, SPAM outperforms state-of-the-art memory-efficient optimizers such as GaLore and Adam-Mini. Our work underscores the importance of mitigating gradient spikes in LLM training and introduces an effective optimization strategy that enhances both training stability and resource efficiency at scale. Code is available at https://github.com/TianjinYellow/SPAM-Optimizer.git

cs.LG

TBDLNet: a network for classifying multidrug-resistant and drug-sensitive tuberculosis

This paper proposes applying a novel deep-learning model, TBDLNet, to recognize CT images to classify multidrug-resistant and drug-sensitive tuberculosis automatically. The pre-trained ResNet50 is selected to extract features. Three randomized neural networks are used to alleviate the overfitting problem. The ensemble of three RNNs is applied to boost the robustness via majority voting. The proposed model is evaluated by five-fold cross-validation. Five indexes are selected in this paper, which are accuracy, sensitivity, precision, F1-score, and specificity. The TBDLNet achieves 0.9822 accuracy, 0.9815 specificity, 0.9823 precision, 0.9829 sensitivity, and 0.9826 F1-score, respectively. The TBDLNet is suitable for classifying multidrug-resistant tuberculosis and drug-sensitive tuberculosis. It can detect multidrug-resistant pulmonary tuberculosis as early as possible, which helps to adjust the treatment plan in time and improve the treatment effect.

eess.IV