arXiv subjects

Ziwei Zhao

Publications and source records attributed to Ziwei Zhao.

35 records · Page 2Linked to original sources

arXiv2024

Robust evaluation of vaccine effects based on estimation of vaccine efficacy curve

Background: The Cox model and its extensions assuming proportional hazards is widely used to estimate vaccine efficacy (VE). In the typical situation that VE wanes over time, the VE estimates are not only sensitive to study duration and timing of vaccine delivery in relation to disease seasonality but also biased in the presence of sample attrition. Furthermore, estimates of vaccine impact such as number of cases averted (NCA) are sensitive to background disease incidence and timing of vaccine delivery. Comparison of the estimates between trials with different features can be misleading. Methods: We propose estimation of VE as a function of time in the Cox model framework, using the area under the VE curve as a summary measure of VE, and extension of the method to estimate vaccine impact. We use simulations and re-analysis of a RTS,S/AS01 malaria vaccine trial dataset to demonstrate their properties and applications. Results: Simulation under scenarios with different trial duration, magnitude of sample attrition and timing of vaccine delivery, all assuming vaccine protection wanes over time, demonstrated the problems of conventional methods assuming proportional hazard, robustness and unbiasedness of the proposed methods, and comparability of the proposed estimates of vaccine efficacy and impact across trials with different features. Furthermore, the proposed NCA estimators are informative in determining the optimal vaccine delivery strategy in regions with highly seasonal disease transmission. Conclusions: The proposed method based on estimation of vaccine efficacy trajectory provides a robust, unbiased, and flexible approach to evaluate vaccine effects.

stat.AP↗

arXiv2024

Ego-Exo4D: Understanding Skilled Human Activity from First- and Third-Person Perspectives

We present Ego-Exo4D, a diverse, large-scale multimodal multiview video dataset and benchmark challenge. Ego-Exo4D centers around simultaneously-captured egocentric and exocentric video of skilled human activities (e.g., sports, music, dance, bike repair). 740 participants from 13 cities worldwide performed these activities in 123 different natural scene contexts, yielding long-form captures from 1 to 42 minutes each and 1,286 hours of video combined. The multimodal nature of the dataset is unprecedented: the video is accompanied by multichannel audio, eye gaze, 3D point clouds, camera poses, IMU, and multiple paired language descriptions -- including a novel "expert commentary" done by coaches and teachers and tailored to the skilled-activity domain. To push the frontier of first-person video understanding of skilled human activity, we also present a suite of benchmark tasks and their annotations, including fine-grained activity understanding, proficiency estimation, cross-view translation, and 3D hand/body pose. All resources are open sourced to fuel new research in the community. Project page: http://ego-exo4d-data.org/

cs.CV↗

arXiv2024

Efficient automatic segmentation for multi-level pulmonary arteries: The PARSE challenge

Efficient automatic segmentation of multi-level (i.e. main and branch) pulmonary arteries (PA) in CTPA images plays a significant role in clinical applications. However, most existing methods concentrate only on main PA or branch PA segmentation separately and ignore segmentation efficiency. Besides, there is no public large-scale dataset focused on PA segmentation, which makes it highly challenging to compare the different methods. To benchmark multi-level PA segmentation algorithms, we organized the first \textbf{P}ulmonary \textbf{AR}tery \textbf{SE}gmentation (PARSE) challenge. On the one hand, we focus on both the main PA and the branch PA segmentation. On the other hand, for better clinical application, we assign the same score weight to segmentation efficiency (mainly running time and GPU memory consumption during inference) while ensuring PA segmentation accuracy. We present a summary of the top algorithms and offer some suggestions for efficient and accurate multi-level PA automatic segmentation. We provide the PARSE challenge as open-access for the community to benchmark future algorithm developments at \url{https://parse2022.grand-challenge.org/Parse2022/}.

eess.IV↗

arXiv2024

Case-Enhanced Vision Transformer: Improving Explanations of Image Similarity with a ViT-based Similarity Metric

This short paper presents preliminary research on the Case-Enhanced Vision Transformer (CEViT), a similarity measurement method aimed at improving the explainability of similarity assessments for image data. Initial experimental results suggest that integrating CEViT into k-Nearest Neighbor (k-NN) classification yields classification accuracy comparable to state-of-the-art computer vision models, while adding capabilities for illustrating differences between classes. CEViT explanations can be influenced by prior cases, to illustrate aspects of similarity relevant to those cases.

cs.CV↗

arXiv2024

Knowledge-driven AI-generated data for accurate and interpretable breast ultrasound diagnoses

Data-driven deep learning models have shown great capabilities to assist radiologists in breast ultrasound (US) diagnoses. However, their effectiveness is limited by the long-tail distribution of training data, which leads to inaccuracies in rare cases. In this study, we address a long-standing challenge of improving the diagnostic model performance on rare cases using long-tailed data. Specifically, we introduce a pipeline, TAILOR, that builds a knowledge-driven generative model to produce tailored synthetic data. The generative model, using 3,749 lesions as source data, can generate millions of breast-US images, especially for error-prone rare cases. The generated data can be further used to build a diagnostic model for accurate and interpretable diagnoses. In the prospective external evaluation, our diagnostic model outperforms the average performance of nine radiologists by 33.5% in specificity with the same sensitivity, improving their performance by providing predictions with an interpretable decision-making process. Moreover, on ductal carcinoma in situ (DCIS), our diagnostic model outperforms all radiologists by a large margin, with only 34 DCIS lesions in the source data. We believe that TAILOR can potentially be extended to various diseases and imaging modalities.

eess.IV↗

arXiv2024

Knowledge Graph Pruning for Recommendation

Recent years have witnessed the prosperity of knowledge graph based recommendation system (KGRS), which enriches the representation of users, items, and entities by structural knowledge with striking improvement. Nevertheless, its unaffordable computational cost still limits researchers from exploring more sophisticated models. We observe that the bottleneck for training efficiency arises from the knowledge graph, which is plagued by the well-known issue of knowledge explosion. Recently, some works have attempted to slim the inflated KG via summarization techniques. However, these summarized nodes may ignore the collaborative signals and deviate from the facts that nodes in knowledge graph represent symbolic abstractions of entities from the real-world. To this end, in this paper, we propose a novel approach called KGTrimmer for knowledge graph pruning tailored for recommendation, to remove the unessential nodes while minimizing performance degradation. Specifically, we design an importance evaluator from a dual-view perspective. For the collective view, we embrace the idea of collective intelligence by extracting community consensus based on abundant collaborative signals, i.e. nodes are considered important if they attract attention of numerous users. For the holistic view, we learn a global mask to identify the valueless nodes from their inherent properties or overall popularity. Next, we build an end-to-end importance-aware graph neural network, which injects filtered knowledge to enhance the distillation of valuable user-item collaborative signals. Ultimately, we generate a pruned knowledge graph with lightweight, stable, and robust properties to facilitate the following-up recommendation task. Extensive experiments are conducted on three publicly available datasets to prove the effectiveness and generalization ability of KGTrimmer.

cs.IR↗

arXiv2024

When Box Meets Graph Neural Network in Tag-aware Recommendation

Last year has witnessed the re-flourishment of tag-aware recommender systems supported by the LLM-enriched tags. Unfortunately, though large efforts have been made, current solutions may fail to describe the diversity and uncertainty inherent in user preferences with only tag-driven profiles. Recently, with the development of geometry-based techniques, e.g., box embedding, diversity of user preferences now could be fully modeled as the range within a box in high dimension space. However, defect still exists as these approaches are incapable of capturing high-order neighbor signals, i.e., semantic-rich multi-hop relations within the user-tag-item tripartite graph, which severely limits the effectiveness of user modeling. To deal with this challenge, in this paper, we propose a novel algorithm, called BoxGNN, to perform the message aggregation via combination of logical operations, thereby incorporating high-order signals. Specifically, we first embed users, items, and tags as hyper-boxes rather than simple points in the representation space, and define two logical operations to facilitate the subsequent process. Next, we perform the message aggregation mechanism via the combination of logical operations, to obtain the corresponding high-order box representations. Finally, we adopt a volume-based learning objective with Gumbel smoothing techniques to refine the representation of boxes. Extensive experiments on two publicly available datasets and one LLM-enhanced e-commerce dataset have validated the superiority of BoxGNN compared with various state-of-the-art baselines. The code is released online

cs.IR↗

arXiv2024

Choroidal Vessel Segmentation on Indocyanine Green Angiography Images via Human-in-the-Loop Labeling

Human-in-the-loop (HITL) strategy has been recently introduced into the field of medical image processing. Indocyanine green angiography (ICGA) stands as a well-established examination for visualizing choroidal vasculature and detecting chorioretinal diseases. However, the intricate nature of choroidal vascular networks makes large-scale manual segmentation of ICGA images challenging. Thus, the study aims to develop a high-precision choroidal vessel segmentation model with limited labor using HITL framework. We utilized a multi-source ICGA dataset, including 55 degree view and ultra-widefield ICGA (UWF-ICGA) images for model development. The choroidal vessel network was pre-segmented by a pre-trained vessel segmentation model, and then manually modified by two ophthalmologists. Choroidal vascular diameter, density, complexity, tortuosity, and branching angle were automatically quantified based on the segmentation. We finally conducted four cycles of HITL. One hundred and fifty 55 degree view ICGA images were used for the first three cycles (50 images per cycle), and twenty UWF-ICGA images for the last cycle. The average time needed to manually correct a pre-segmented ICGA image per cycle reduced from 20 minutes to 1 minute. High segmentation accuracy has been achieved on both 55 degree view ICGA and UWF-ICGA images. Additionally, the multi-dimensional choroidal vascular parameters were significantly associated with various chorioretinal diseases. Our study not only demonstrated the feasibility of the HITL strategy in improving segmentation performance with reduced manual labeling, but also innovatively introduced several risk predictors for choroidal abnormalities.

eess.IV↗

arXiv2024

DynLLM: When Large Language Models Meet Dynamic Graph Recommendation

Last year has witnessed the considerable interest of Large Language Models (LLMs) for their potential applications in recommender systems, which may mitigate the persistent issue of data sparsity. Though large efforts have been made for user-item graph augmentation with better graph-based recommendation performance, they may fail to deal with the dynamic graph recommendation task, which involves both structural and temporal graph dynamics with inherent complexity in processing time-evolving data. To bridge this gap, in this paper, we propose a novel framework, called DynLLM, to deal with the dynamic graph recommendation task with LLMs. Specifically, DynLLM harnesses the power of LLMs to generate multi-faceted user profiles based on the rich textual features of historical purchase records, including crowd segments, personal interests, preferred categories, and favored brands, which in turn supplement and enrich the underlying relationships between users and items. Along this line, to fuse the multi-faceted profiles with temporal graph embedding, we engage LLMs to derive corresponding profile embeddings, and further employ a distilled attention mechanism to refine the LLM-generated profile embeddings for alleviating noisy signals, while also assessing and adjusting the relevance of each distilled facet embedding for seamless integration with temporal graph embedding from continuous time dynamic graphs (CTDGs). Extensive experiments on two real e-commerce datasets have validated the superior improvements of DynLLM over a wide range of state-of-the-art baseline methods.

cs.IR↗

arXiv2024

EyeGPT: Ophthalmic Assistant with Large Language Models

Artificial intelligence (AI) has gained significant attention in healthcare consultation due to its potential to improve clinical workflow and enhance medical communication. However, owing to the complex nature of medical information, large language models (LLM) trained with general world knowledge might not possess the capability to tackle medical-related tasks at an expert level. Here, we introduce EyeGPT, a specialized LLM designed specifically for ophthalmology, using three optimization strategies including role-playing, finetuning, and retrieval-augmented generation. In particular, we proposed a comprehensive evaluation framework that encompasses a diverse dataset, covering various subspecialties of ophthalmology, different users, and diverse inquiry intents. Moreover, we considered multiple evaluation metrics, including accuracy, understandability, trustworthiness, empathy, and the proportion of hallucinations. By assessing the performance of different EyeGPT variants, we identify the most effective one, which exhibits comparable levels of understandability, trustworthiness, and empathy to human ophthalmologists (all Ps>0.05). Overall, ur study provides valuable insights for future research, facilitating comprehensive comparisons and evaluations of different strategies for developing specialized LLMs in ophthalmology. The potential benefits include enhancing the patient experience in eye care and optimizing ophthalmologists' services.

cs.CL↗

arXiv2023

Topology-Preserving Automatic Labeling of Coronary Arteries via Anatomy-aware Connection Classifier

Automatic labeling of coronary arteries is an essential task in the practical diagnosis process of cardiovascular diseases. For experienced radiologists, the anatomically predetermined connections are important for labeling the artery segments accurately, while this prior knowledge is barely explored in previous studies. In this paper, we present a new framework called TopoLab which incorporates the anatomical connections into the network design explicitly. Specifically, the strategies of intra-segment feature aggregation and inter-segment feature interaction are introduced for hierarchical segment feature extraction. Moreover, we propose the anatomy-aware connection classifier to enable classification for each connected segment pair, which effectively exploits the prior topology among the arteries with different categories. To validate the effectiveness of our method, we contribute high-quality annotations of artery labeling to the public orCaScore dataset. The experimental results on both the orCaScore dataset and an in-house dataset show that our TopoLab has achieved state-of-the-art performance.

eess.IV↗

arXiv2023

Mining Negative Temporal Contexts For False Positive Suppression In Real-Time Ultrasound Lesion Detection

During ultrasonic scanning processes, real-time lesion detection can assist radiologists in accurate cancer diagnosis. However, this essential task remains challenging and underexplored. General-purpose real-time object detection models can mistakenly report obvious false positives (FPs) when applied to ultrasound videos, potentially misleading junior radiologists. One key issue is their failure to utilize negative symptoms in previous frames, denoted as negative temporal contexts (NTC). To address this issue, we propose to extract contexts from previous frames, including NTC, with the guidance of inverse optical flow. By aggregating extracted contexts, we endow the model with the ability to suppress FPs by leveraging NTC. We call the resulting model UltraDet. The proposed UltraDet demonstrates significant improvement over previous state-of-the-arts and achieves real-time inference speed. We release the code, checkpoints, and high-quality labels of the CVA-BUS dataset in https://github.com/HaojunYu1998/UltraDet.

cs.CV↗

arXiv2022

PointScatter: Point Set Representation for Tubular Structure Extraction

This paper explores the point set representation for tubular structure extraction tasks. Compared with the traditional mask representation, the point set representation enjoys its flexibility and representation ability, which would not be restricted by the fixed grid as the mask. Inspired by this, we propose PointScatter, an alternative to the segmentation models for the tubular structure extraction task. PointScatter splits the image into scatter regions and parallelly predicts points for each scatter region. We further propose the greedy-based region-wise bipartite matching algorithm to train the network end-to-end and efficiently. We benchmark the PointScatter on four public tubular datasets, and the extensive experiments on tubular structure segmentation and centerline extraction task demonstrate the effectiveness of our approach. Code is available at https://github.com/zhangzhao2022/pointscatter.

cs.CV↗

arXiv2022

Check and Link: Pairwise Lesion Correspondence Guides Mammogram Mass Detection

Detecting mass in mammogram is significant due to the high occurrence and mortality of breast cancer. In mammogram mass detection, modeling pairwise lesion correspondence explicitly is particularly important. However, most of the existing methods build relatively coarse correspondence and have not utilized correspondence supervision. In this paper, we propose a new transformer-based framework CL-Net to learn lesion detection and pairwise correspondence in an end-to-end manner. In CL-Net, View-Interactive Lesion Detector is proposed to achieve dynamic interaction across candidates of cross views, while Lesion Linker employs the correspondence supervision to guide the interaction process more accurately. The combination of these two designs accomplishes precise understanding of pairwise lesion correspondence for mammograms. Experiments show that CL-Net yields state-of-the-art performance on the public DDSM dataset and our in-house dataset. Moreover, it outperforms previous methods by a large margin in low FPI regime.

cs.CV↗

arXiv2022

Ego4D: Around the World in 3,000 Hours of Egocentric Video

We introduce Ego4D, a massive-scale egocentric video dataset and benchmark suite. It offers 3,670 hours of daily-life activity video spanning hundreds of scenarios (household, outdoor, workplace, leisure, etc.) captured by 931 unique camera wearers from 74 worldwide locations and 9 different countries. The approach to collection is designed to uphold rigorous privacy and ethics standards with consenting participants and robust de-identification procedures where relevant. Ego4D dramatically expands the volume of diverse egocentric video footage publicly available to the research community. Portions of the video are accompanied by audio, 3D meshes of the environment, eye gaze, stereo, and/or synchronized videos from multiple egocentric cameras at the same event. Furthermore, we present a host of new benchmark challenges centered around understanding the first-person visual experience in the past (querying an episodic memory), present (analyzing hand-object manipulation, audio-visual conversation, and social interactions), and future (forecasting activities). By publicly sharing this massive annotated dataset and benchmark suite, we aim to push the frontier of first-person perception. Project page: https://ego4d-data.org/

cs.CV↗

arXiv2021

Applying the Case Difference Heuristic to Learn Adaptations from Deep Network Features

The case difference heuristic (CDH) approach is a knowledge-light method for learning case adaptation knowledge from the case base of a case-based reasoning system. Given a pair of cases, the CDH approach attributes the difference in their solutions to the difference in the problems they solve, and generates adaptation rules to adjust solutions accordingly when a retrieved case and new query have similar problem differences. As an alternative to learning adaptation rules, several researchers have applied neural networks to learn to predict solution differences from problem differences. Previous work on such approaches has assumed that the feature set describing problems is predefined. This paper investigates a two-phase process combining deep learning for feature extraction and neural network based adaptation learning from extracted features. Its performance is demonstrated in a regression task on an image data: predicting age given the image of a face. Results show that the combined process can successfully learn adaptation knowledge applicable to nonsymbolic differences in cases. The CBR system achieves slightly lower performance overall than a baseline deep network regressor, but better performance than the baseline on novel queries.

cs.AI↗

arXiv2019

FPGA-based Binocular Image Feature Extraction and Matching System

Image feature extraction and matching is a fundamental but computation intensive task in machine vision. This paper proposes a novel FPGA-based embedded system to accelerate feature extraction and matching. It implements SURF feature point detection and BRIEF feature descriptor construction and matching. For binocular stereo vision, feature matching includes both tracking matching and stereo matching, which simultaneously provide feature point correspondences and parallax information. Our system is evaluated on a ZYNQ XC7Z045 FPGA. The result demonstrates that it can process binocular video data at a high frame rate (640$\times$480 @ 162fps). Moreover, an extensive test proves our system has robustness for image compression, blurring and illumination.

cs.CV↗